Cannabis use and psychosocial adjustment in adolescence and young adulthood
Abstract
Aim: To examine the associations between frequency of cannabis use and psychosocial outcomes in adolescence/young adulthood. Design: A 21‐year longitudinal study of the health, development and adjustment of a birth cohort of 1265 New Zealand children. Measurements: Annual assessments of the frequency of cannabis use were obtained for the period from age 14–21 years, together with measures of psychosocial outcomes including property/violent crime, depression, suicidal ideation, suicide attempt and other illicit drug use. Findings: The frequency of cannabis use was associated significantly with all outcomes, and particularly other illicit drug use. Statistical control for confounding by both fixed and time‐dynamic factors substantially reduced the strength of association between cannabis use and outcome measures. Nevertheless, cannabis use remained significantly (P < 0.05) associated with all outcomes and particularly other illicit drug use, after adjustment for confounding. For the measures of crime, suicidal behaviours and other illicit drug use there was evidence of age related variation in the strength of association with cannabis use, with younger (14–15 years old) users being more affected by regular cannabis use than older (20–21 years old) regular users. However, the association between cannabis use and depression did not vary with age. Conclusions: Cannabis use, and particularly regular or heavy use, was associated with increased rates of a range of adjustment problems in adolescence/ young adulthood—other illicit drug use, crime, depression and suicidal behaviours—with these adverse effects being most evident for school‐aged regular users. The findings reinforce public health concerns about minimizing the use of cannabis among school‐aged populations.
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There is evidence that younger users of cannabis (aged 14 to 15 years) were at significantly higher risk of suicidal behaviors, although overall the association between cannabis use and depression did not vary with age.
“There is evidence that younger users of cannabis (aged 14 to 15 years) were at significantly higher risk of suicidal behaviors, although, overall, the association between cannabis use and depression did not vary with age 42”
From Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood (2019) · cites this paper as [42]
Non-compliance to treatment or deviation from treatment plan will not lead to exclusion of participants, based on the intention-to-treat principle.
“Based on the intention-to-treat principle, non-compliance to the treatment or deviation from the treatment plan will not lead to the exclusion of participants.44”
Cites
Longitudinal data analysis using generalized linear models
LIANG, K.-Y., & ZEGER, S. L. (1986) · Biometrika · doi:10.1093/biomet/73.1.13 · Cited by 18,550 · see citing works
Diagnostic and Statistical Manual of Mental Disorders
&NA; (1988) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-198802020-00022 · Cited by 12,603 · see citing works
Drake, M. M. (1988) · American Journal of Occupational Therapy · doi:10.5014/ajot.42.10.683b · Cited by 5,303 · see citing works
The theory and practice of econometrics
(1986) · Journal of Macroeconomics · doi:10.1016/0164-0704(86)90027-3 · Cited by 4,369 · see citing works
Econometric Models for Count Data with an Application to the Patents-R & D Relationship
Hausman, J., Hall, B. H., & Griliches, Z. (1984) · Econometrica · doi:10.2307/1911191 · Cited by 3,393 · see citing works
Diagnostic and Statistical Manual of Mental Disorders
Sciacca, F., Sharma, R., & Knipe, H. (2020) · Radiopaedia.org · doi:10.53347/rid-80880 · Cited by 2,394 · see citing works
Towards the assessment of adolescent problem drinking
White, H. R., & Labouvie, E. W. (1989) · Journal of Studies on Alcohol · doi:10.15288/jsa.1989.50.30 · Cited by 1,693 · see citing works
How Much Does Childhood Poverty Affect the Life Chances of Children?
Duncan, G. J., Yeung, W. J., Jeanne Brooks-gunn, B., & Smith, J. R. (1998) · American Sociological Review · doi:10.2307/2657556 · Cited by 1,616 · see citing works
Structure of problem behavior in adolescence and young adulthood.
Donovan, J. E., & Jessor, R. (1985) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.53.6.890 · Cited by 1,292 · see citing works
Kandel, D. B., Yamaguchi, K., & Chen, K. (1992) · Journal of Studies on Alcohol · doi:10.15288/jsa.1992.53.447 · Cited by 1,039 · see citing works
Structure of problem behavior in adolescence and young adulthood.
Donovan, J. E., & Jessor, R. (1985) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.53.6.890 · Cited by 935 · see citing works
The Theory and Practice of Econometrics.
Davidson, J., Judge, G. G., Griffiths, W. E., Hill, R. C., & Lee, T.-C. (1981) · Economica · doi:10.2307/2553707 · Cited by 890 · see citing works
Pharmacology and effects of cannabis: A brief review
Ashton, C. (2001) · British Journal of Psychiatry · doi:10.1192/bjp.178.2.101 · Cited by 868 · see citing works
FERGUSSON, D. M., WOODWARD, L. J., & HORWOOD, L. J. (2000) · Psychological Medicine · doi:10.1017/s003329179900135x · Cited by 832 · see citing works
Self-citationHall, W., & Solowij, N. (1998) · The Lancet · doi:10.1016/s0140-6736(98)05021-1 · Cited by 778 · see citing works
THE COMPOSITE INTERNATIONAL DIAGNOSTIC INTERVIEW (CIDI)
Robins, L. N. (1994) · IX World Congress of Psychiatry · doi:10.1142/9789814440912_0056 · Cited by 574 · see citing works
Early onset cannabis use and psychosocial adjustment in young adults
Fergusson, D. M., & Horwood, L. J. (1997) · Addiction · doi:10.1111/j.1360-0443.1997.tb03198.x · Cited by 493 · see citing works
Self-citationThe Consequences in Young Adulthood of Adolescent Drug Involvement
Kandel, D. B. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800080032005 · Cited by 484 · see citing works
Psychiatric effects of cannabis
Johns, A. (2001) · The British Journal of Psychiatry · doi:10.1192/bjp.178.2.116 · Cited by 472 · see citing works
Adolescent substance abuse: a review of the past 10 years.
Weinberg, N. Z., Rahdert, E., Colliver, J., & Glantz, M. (1998) · Journal of the American Academy of Child and Adolescent Psychiatry · doi:10.1097/00004583-199803000-00009 · Cited by 427 · see citing works
Fergusson, D. M., & Horwood, L. J. (2001) · Australian & New Zealand Journal of Psychiatry · doi:10.1046/j.1440-1614.2001.00902.x · Cited by 423 · see citing works
Self-citationPsychosocial Correlates of Marijuana Use and Problem Drinking in a National Sample of Adolescents
Jessor, R., Chase, J. A., & Donovan, J. E. (1980) · American Journal of Public Health · doi:10.2105/ajph.70.6.604 · Cited by 351 · see citing works
Does cannabis use encourage other forms of illicit drug use?
Fergusson, D. M., & Horwood, L. J. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.9545053.x · Cited by 321 · see citing works
Self-citationLongitudinal study of co-occurring psychiatric disorders and substance use.
BROOK, J. S., COHEN, P., & BROOK, D. W. (1998) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199803000-00018 · Cited by 308 · see citing works
A longitudinal study of cannabis use and mental health from adolescence to early adulthood
McGee, R. O., Williams, S., Poulton, R., & Moffitt, T. E. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.9544912.x · Cited by 298 · see citing works
The Christchurch Child Development Study: a review of epidemiological findings
Fergusson, D. M., Horwood, L. J., Shannon, F. T., & Lawton, J. M. (1989) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.1989.tb00382.x · Cited by 290 · see citing works
Self-citationSelf-reported delinquency: Results from an instrument for New Zealand
Moffitt, T. E., & Silva, P. A. (1988) · Australian & New Zealand Journal of Criminology · doi:10.1177/000486588802100405 · Cited by 283 · see citing works
Prospective Childhood Predictors of Deviant Peer Affiliations in Adolescence
Fergusson, D. M., & Horwood, L. J. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00475 · Cited by 268 · see citing works
Self-citationHousework, Fixed Effects, and Wages of Married Workers
Hersch, J., & Stratton, L. S. (1997) · The Journal of Human Resources · doi:10.2307/146216 · Cited by 239 · see citing works
The risks for late adolescence of early adolescent marijuana use
Brook, J. S., Balka, E. B., & Whiteman, M. (1999) · American Journal of Public Health · doi:10.2105/ajph.89.10.1549 · Cited by 225 · see citing works
Feeling bad: exploring sources of distress among pre-adolescent children.
Lewis, C. E., Siegel, J. M., & Lewis, M. A. (1984) · American Journal of Public Health · doi:10.2105/ajph.74.2.117 · Cited by 200 · see citing works
Improving Self-Reported Measures of Delinquency
Elliott, D. S., & Huizinga, D. H. (1989) · Springer eBooks · doi:10.1007/978-94-009-1001-0_8 · Cited by 199 · see citing works
Unemployment and psychosocial adjustment in young adults: causation or selection?
Fergusson, D. M., Horwood, L. J., & Woodward, L. J. (2001) · Social Science & Medicine · doi:10.1016/s0277-9536(00)00344-0 · Cited by 193 · see citing works
Self-citationMiller, S., Lochman, J. E., Coie, J. D., Terry, R., & Hyman, C. (1998) · Research on Child and Adolescent Psychopathology · doi:10.1023/a:1022676302865 · Cited by 147 · see citing works
Recent trends in the prevalence and secondary prevention of Down's syndrome
Stone, D. H., Rosenberg, K., & Womersley, J. (1989) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.1989.tb00379.x · Cited by 138 · see citing works
Fergusson, D. M., & Horwood, L. J. (1996) · Research on Child and Adolescent Psychopathology · doi:10.1007/bf01441485 · Cited by 136 · see citing works
Self-citationAlcohol abuse and crime: a fixed‐effects regression analysis
Fergusson, D. M., & Horwood, L. J. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.951015257.x · Cited by 129 · see citing works
Self-citationCannabis use and dependence in a New Zealand birth cohort.
Fergusson, D. M., & Horwood, L. J. (2000) · PubMed · Cited by 112 · see citing works
Self-citationCannabis use and public health: assessing the burden
Hall, W., & Babor, T. F. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.9544851.x · Cited by 90 · see citing works
Panel Analysis for Qualitative Variables
Hamerle, A., & Ronning, G. (1995) · Springer eBooks · doi:10.1007/978-1-4899-1292-3_8 · Cited by 88 · see citing works
Stability of Psychological Symptoms: Drug Use Consequences and Intervening Processes
Johnson, R. J., & Kaplan, H. B. (1990) · Journal of Health and Social Behavior · doi:10.2307/2136892 · Cited by 85 · see citing works
Greenfield, T. K., & Weisner, C. M. (2003) · Addiction · doi:10.1046/j.1360-0443.1995.9033616.x · Cited by 71 · see citing works
Prevalence and correlates of cannabis use and dependence in young New Zealanders.
Poulton, R., Brooke, M., Moffitt, T. E., Stanton, W. R., & Silva, P. A. (1997) · PubMed · Cited by 69 · see citing works
Childhood psychopathology retrospectively assessed among adults with early onset major depression
Alpert, J. E., Maddocks, A., Rosenbaum, J. F., & Fava, M. (1994) · Journal of Affective Disorders · doi:10.1016/0165-0327(94)90025-6 · Cited by 60 · see citing works
Multiple Drug Use Considered in the Light of the Stepping-Stone Hypothesis
Cohen, H. (1972) · International Journal of the Addictions · doi:10.3109/10826087209026759 · Cited by 43 · see citing works
Patterns of cannabis use among 13-14 year old New Zealanders.
Fergusson, D. M., Lynskey, M. T., & Horword, L. J. (1993) · PubMed · Cited by 22 · see citing works
Self-citationSubstance use and personal adjustment among disadvantaged teenagers: A six-month prospective study
Luthar, S. S., & Cushing, G. (1997) · Journal of Youth and Adolescence · doi:10.1007/s10964-005-0007-1 · Cited by 16 · see citing works
NEUROPSYCHOLOGICAL FUNCTIONING IN SUBSTANCE-DEPENDENT PATIENTS
Paraherakis, A. M., Charney, D. A., & Gill, K. J. (2001) · Substance Use & Misuse · doi:10.1081/ja-100102625 · Cited by 16 · see citing works
Crime, illegal drug use and social control in the transition from school to work
Hartnagel, T. F. (1997) · Criminal Behaviour and Mental Health · doi:10.1002/cbm.192 · Cited by 12 · see citing works
Cannabis as a gateway drug: comments on Fergusson & Horwood (2000).
Midanik, L. T. (2001) · PubMed · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review.
Moore, T. H., Zammit, S., Lingford-Hughes, A., Barnes, T. R., Jones, P. B., Burke, M., & Lewis, G. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61162-3 · Cited by 2,224 · see citing works
Gobbi, G., Atkin, T., Zytynski, T., Wang, S., Askari, S., Boruff, J., Ware, M., Marmorstein, N., Cipriani, A., Dendukuri, N., et al. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.4500 · Cited by 914 · see citing works
Macleod, J., Oakes, R., Copello, A., Crome, I., Egger, M., Hickman, M., Oppenkowski, T., Stokes-Lampard, H., & Smith, G. D. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16200-4 · Cited by 639 · see citing works
Lev-Ran, S., Roerecke, M., Le Foll, B., George, T. P., McKenzie, K., & Rehm, J. (2014) · Psychological Medicine · doi:10.1017/s0033291713001438 · Cited by 589 · see citing works
Exploring the association between cannabis use and depression.
Degenhardt, L., Hall, W., & Lynskey, M. (2003) · Addiction · doi:10.1046/j.1360-0443.2003.00437.x · Cited by 587 · see citing works
Cannabis dependence and psychotic symptoms in young people
FERGUSSON, D. M., HORWOOD, L. J., & SWAIN-CAMPBELL, N. R. (2003) · Psychological Medicine · doi:10.1017/s0033291702006402 · Cited by 415 · see citing works
Self-citationStress-related factors in cannabis use and misuse: Implications for prevention and treatment
Hyman, S. M., & Sinha, R. (2009) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2008.08.005 · Cited by 344 · see citing works
Wittchen, H.-U., Fröhlich, C., Behrendt, S., Günther, A., Rehm, J., Zimmermann, P., Lieb, R., & Perkonigg, A. (2007) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2006.12.013 · Cited by 311 · see citing works
Cannabis use and educational achievement: Findings from three Australasian cohort studies
Horwood, L. J., Fergusson, D. M., Hayatbakhsh, M. R., Najman, J. M., Coffey, C., Patton, G. C., Silins, E., & Hutchinson, D. M. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.03.008 · Cited by 302 · see citing works
Self-citationHaller, J., Varga, B., Ledent, C., Barna, I., & Freund, T. F. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03293.x · Cited by 284 · see citing works
Tests of causal linkages between cannabis use and psychotic symptoms
Fergusson, D. M., Horwood, L. J., & Ridder, E. M. (2005) · Addiction · doi:10.1111/j.1360-0443.2005.01001.x · Cited by 268 · see citing works
Self-citationTiffany, S. T., Friedman, L., Greenfield, S. F., Hasin, D. S., & Jackson, R. (2012) · Addiction · doi:10.1111/j.1360-0443.2011.03581.x · Cited by 236 · see citing works
Cannabis and psychiatric disorders: it is not only addiction
Leweke, F. M., & Koethe, D. (2008) · Addiction Biology · doi:10.1111/j.1369-1600.2008.00106.x · Cited by 213 · see citing works
A literature review and meta-analyses of cannabis use and suicidality
Borges, G., Bagge, C. L., & Orozco, R. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.02.007 · Cited by 214 · see citing works
Cannabis use during adolescent development: Susceptibility to psychiatric illness
Chadwick, B., Miller, M. L., & Hurd, Y. L. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00129 · Cited by 210 · see citing works
Global use of alcohol, drugs and tobacco
ANDERSON, P. (2006) · Drug and Alcohol Review · doi:10.1080/09595230600944446 · Cited by 151 · see citing works
Long lasting consequences of cannabis exposure in adolescence
Rubino, T., & Parolaro, D. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.02.003 · Cited by 152 · see citing works
Cannabis and the developing brain: Insights from behavior
Trezza, V., Cuomo, V., & Vanderschuren, L. J. M. J. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.01.058 · Cited by 131 · see citing works
Meier, M. H., Hill, M. L., Small, P. J., & Luthar, S. S. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.09.010 · Cited by 116 · see citing works
Cannabis and suicide: Longitudinal study
Price, C., Hemmingsson, T., Lewis, G., Zammit, S., & Allebeck, P. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.109.065227 · Cited by 97 · see citing works
Motivational and mindfulness intervention for young adult female marijuana users
de Dios, M. A., Herman, D. S., Britton, W. B., Hagerty, C. E., Anderson, B. J., & Stein, M. D. (2012) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2011.08.001 · Cited by 86 · see citing works
Harder, V. S., Stuart, E. A., & Anthony, J. C. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn184 · Cited by 76 · see citing works
“Is medical cannabis safe for my patients?” A practical review of cannabis safety considerations
MacCallum, C. A., Lo, L. A., & Boivin, M. (2021) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2021.05.002 · Cited by 71 · see citing works
Primary Prevention of Cannabis Use: A Systematic Review of Randomized Controlled Trials
Norberg, M. M., Kezelman, S., & Lim-Howe, N. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053187 · Cited by 68 · see citing works
Explaining the relationship between religiousness and substance use: Self-control matters.
DeWall, C. N., Pond, R. S., Carter, E. C., McCullough, M. E., Lambert, N. M., Fincham, F. D., & Nezlek, J. B. (2014) · Journal of Personality and Social Psychology · doi:10.1037/a0036853 · Cited by 68 · see citing works
Schaefer, J. D., Hamdi, N. R., Malone, S. M., Vrieze, S., Wilson, S., McGue, M., & Iacono, W. G. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2013180118 · Cited by 64 · see citing works
Trim, R. S., Meehan, B. T., King, K. M., & Chassin, L. (2007) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.21.1.97 · Cited by 62 · see citing works
Developmental Pathways to Substance Abuse
Mayes, L. C., & Suchman, N. E. (2015) · Developmental Psychopathology · doi:10.1002/9780470939406.ch16 · Cited by 54 · see citing works
Cannabis use and mental health-related quality of life among individuals with anxiety disorders
Lev-Ran, S., Le Foll, B., McKenzie, K., & Rehm, J. (2012) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2012.07.002 · Cited by 39 · see citing works
Otten, R., & Engels, R. C. M. E. (2013) · Addiction Biology · doi:10.1111/j.1369-1600.2011.00380.x · Cited by 34 · see citing works
Stein, M. D., Caviness, C. M., Morse, E. F., Grimone, K. R., Audet, D., Herman, D. S., Moitra, E., & Anderson, B. J. (2018) · Addiction · doi:10.1111/add.14026 · Cited by 33 · see citing works
Kava drinking associated with suicidal behaviour among young Kanaks using kava in New Caledonia.
Vignier, N., Lert, F., Salomon, C., & Hamelin, C. (2011) · Australian and New Zealand Journal of Public Health · doi:10.1111/j.1753-6405.2011.00737.x · Cited by 10 · see citing works
Chapter 4.5 The endocannabinoid system and anxiety responses
Bortolato, M., & Piomelli, D. (2008) · Handbook of Behavioral Neuroscience · doi:10.1016/s1569-7339(07)00014-8 · Cited by 7 · see citing works
Schmidt, K. L., Kowalski, A., Schweda, A., Dörrie, N., Skoda, E. M., Bäuerle, A., & Teufel, M. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-079098 · Cited by 3 · see citing works
“44 To perform the imputation, the SPSS multiple imputation module will be used.”
Method
- Authors
- Fergusson, D. M., Horwood, L. J., & Swain‐Campbell, N.
- Corresponding author
- Fergusson, David M.
- Venue
- Addiction
- Publisher
- Wiley
- Published
- 2002-08-30
- Volume
- 97
- Issue
- 9
- Pages
- 1123-1135
- ISSN
- 0965-2140 (ISSN-L)
- 1360-0443
- OpenAlex
- W2094076298
- Cited by
- 563
- References
- 50
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 6 · 2023: 15 · 2022: 13 · 2021: 14 · 2020: 37 · 2019: 12 · 2018: 23 · 2017: 19 · 2016: 31 · 2015: 32 · 2014: 52 · 2013: 17 · 2012: 33
- FWCI
- 10.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Addiction (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Research Foundation
- Lotto New Zealand
- Health Research Council of New Zealand
- Topics
- Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Keywords
- cannabis use, psychosocial adjustment, adolescence, early adulthood, illicit drug use, crime, violent crime, depression, suicidal ideation, suicide attempts, age effects, school-age adolescents, birth cohort
- MeSH terms
- Adolescent, Adult, Age Factors, Marijuana Abuse, Depressive Disorder, Humans, Longitudinal Studies, New Zealand, Regression Analysis, Risk Factors, Social Adjustment, Suicide, Attempted, Violence, Cohort Studies
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