Liability to substance use disorders: 1. Common mechanisms and manifestations

Vanyukov, Michael M; Tarter, Ralph E; Kirisci, Levent; Kirillova, Galina P; Maher, Brion S; Clark, Duncan B

doi:10.1016/j.neubiorev.2003.08.002

Cited by 205Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on BehaviorGambling Behavior and Treatments

Liability to substance use disorders: 1. Common mechanisms and manifestations

Vanyukov, Michael M, Tarter, Ralph E, Kirisci, Levent, Kirillova, Galina P, Maher, Brion S, Clark, Duncan B·2003·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2003.08.002

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Abstract

Variation in the risk for and severity of substance use disorders (SUD) in the population is caused by multiple organismic (genetic, biochemical, psychological) and environmental factors. Whereas drug- or drug-class-specific liability mechanisms exist, a substantial proportion of variance in the risk is shared between specific liabilities, reflecting mechanisms that determine common liability to SUD. Data from epidemiologic, clinical, psychological, physiological, biochemical, and family and genetic studies reviewed in this paper indicate the existence of mechanisms and characteristics shared in common by liabilities to SUD related to different drugs. These mechanisms can be conceptualized as common liability to SUD, a latent trait accounting for a substantial portion of variation in SUD risk and severity and determined by all factors influencing the probability of SUD development. An accompanying paper describes an approach to the quantitative estimation of this trait.

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A Developmental Perspective on Alcohol and Youths 16 to 20 Years of Age
Brown, S. A., McGue, M., Maggs, J., Schulenberg, J., Hingson, R., Swartzwelder, S., Martin, C., Chung, T., Tapert, S. F., Sher, K., et al. (2008) · Pediatrics · doi:10.1542/peds.2007-2243d · Cited by 612 · see citing works
A review of systems and networks of the limbic forebrain/limbic midbrain
Morgane, P. J., Galler, J. R., & Mokler, D. J. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.01.001 · Cited by 497 · see citing works
Early adolescent patterns of alcohol, cigarettes, and marijuana polysubstance use and young adult substance use outcomes in a nationally representative sample
Moss, H. B., Chen, C. M., & Yi, H. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.12.011 · Cited by 492 · see citing works
Impulsivity-related personality traits and adolescent alcohol use: A meta-analytic review
Stautz, K., & Cooper, A. J. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2013.03.003 · Cited by 486 · see citing works
Trajectories of Alcohol and Drug Use and Dependence From Adolescence to Adulthood: The Effects of Familial Alcoholism and Personality.
Chassin, L., Flora, D. B., & King, K. M. (2004) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.113.4.483 · Cited by 480 · see citing works
Behavioral Disinhibition and the Development of Early-Onset Addiction: Common and Specific Influences
Iacono, W. G., Malone, S. M., & McGue, M. (2008) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.4.022007.141157 · Cited by 554 · see citing works
Common liability to addiction and “gateway hypothesis”: Theoretical, empirical and evolutionary perspective
Vanyukov, M. M., Tarter, R. E., Kirillova, G. P., Kirisci, L., Reynolds, M., Kreek, M. J., Conway, K. P., Maher, B. S., Iacono, W. G., Bierut, L. J., et al. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2011.12.018 · Cited by 438 · see citing works
Neurobiology of addiction
Goodman, A. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.07.030 · Cited by 412 · see citing works
Genetic variation in components of dopamine neurotransmission impacts ventral striatal reactivity associated with impulsivity
Forbes, E. E., Brown, S. M., Kimak, M., Ferrell, R. E., Manuck, S. B., & Hariri, A. R. (2009) · Molecular Psychiatry · doi:10.1038/sj.mp.4002086 · Cited by 408 · see citing works
Cognitive impulsivity in cocaine and heroin polysubstance abusers
Verdejo‐García, A., Perales, J. C., & Pérez-Garcı́a, M. (2006) · Addictive Behaviors · doi:10.1016/j.addbeh.2006.06.032 · Cited by 302 · see citing works
Developmental epidemiology of drug use and abuse in adolescence and young adulthood: Evidence of generalized risk
Palmer, R., Young, S., Hopfer, C., Corley, R., Stallings, M., Crowley, T., & Hewitt, J. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.01.012 · Cited by 292 · see citing works
Adolescent non-suicidal self-injury: A cross-national study of community samples from Italy, the Netherlands and the United States
Giletta, M., Scholte, R. H. J., Engels, R. C. M. E., Ciairano, S., & Prinstein, M. J. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.02.009 · Cited by 228 · see citing works
Alcohol, psychological dysregulation, and adolescent brain development
Clark, D. B., Thatcher, D. L., & Tapert, S. F. (2008) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00601.x · Cited by 222 · see citing works
Adolescent cannabis users at 24 years: trajectories to regular weekly use and dependence in young adulthood
Swift, W., Coffey, C., Carlin, J. B., Degenhardt, L. J., & Patton, G. C. (2008) · Addiction · doi:10.1111/j.1360-0443.2008.02246.x · Cited by 182 · see citing works
Risky behaviors, e-cigarette use and susceptibility of use among college students
Saddleson, M. L., Kozlowski, L. T., Giovino, G. A., Hawk, L. W., Murphy, J. M., MacLean, M. G., Goniewicz, M. L., Homish, G. G., Wrotniak, B. H., & Mahoney, M. C. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.01.001 · Cited by 178 · see citing works
The natural history of adolescent alcohol use disorders
Clark, D. B. (2004) · Addiction · doi:10.1111/j.1360-0443.2004.00851.x · Cited by 172 · see citing works
Predictors of Marijuana Use in Adolescents Before and After Licit Drug Use: Examination of the Gateway Hypothesis
Tarter, R. E., Vanyukov, M., Kirisci, L., Reynolds, M., & Clark, D. B. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.12.2134 · Cited by 164 · see citing works
The genetics of the opioid system and specific drug addictions
Levran, O., Yuferov, V. P., & Kreek, M. J. (2012) · Human Genetics · doi:10.1007/s00439-012-1172-4 · Cited by 143 · see citing works
The Relationship Between Tobacco and Cannabis Use: A Review
Lemyre, A., Poliakova, N., & Bélanger, R. E. (2018) · Substance Use & Misuse · doi:10.1080/10826084.2018.1512623 · Cited by 143 · see citing works
Acute and Non-acute Effects of Cannabis on Brain Functioning and Neuropsychological Performance
González, R. (2007) · Neuropsychology Review · doi:10.1007/s11065-007-9036-8 · Cited by 134 · see citing works
Longitudinal trajectories of sensation seeking, risk taking propensity, and impulsivity across early to middle adolescence
Collado, A., Felton, J. W., MacPherson, L., & Lejuez, C. W. (2014) · Addictive Behaviors · doi:10.1016/j.addbeh.2014.01.024 · Cited by 131 · see citing works
Impulsivity differences in recreational cannabis users and binge drinkers in a university population
Moreno, M., Estévez, Á. F., Basurto, F. Z., Montes, J. M. G., Gutiérrez-Ferre, V. E., Esteban, L., Sánchez-Santed, F., & Flores, P. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.02.011 · Cited by 129 · see citing works
Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in males
Cheng, C., Hong, C., Yu, Y. W. ‐., Chen, T., Wu, H., & Tsai, S. (2005) · Molecular Brain Research · doi:10.1016/j.molbrainres.2005.07.008 · Cited by 125 · see citing works
Sleep and circadian contributions to adolescent alcohol use disorder
Hasler, B. P., Soehner, A. M., & Clark, D. B. (2015) · Alcohol · doi:10.1016/j.alcohol.2014.06.010 · Cited by 123 · see citing works
Circadian Misalignment, Reward‐Related Brain Function, and Adolescent Alcohol Involvement
Hasler, B. P., & Clark, D. B. (2013) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12003 · Cited by 120 · see citing works
Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts
Schwantes-An, T.-H. L., Zhang, J., Chen, L., Hartz, S. M., Culverhouse, R., Chen, X., Coon, H. H., Frank, J., Kamens, H. M., Konte, B., et al. (2015) · Behavior Genetics · doi:10.1007/s10519-015-9737-3 · Cited by 115 · see citing works
Does report of craving opioid medication predict aberrant drug behavior among chronic pain patients
Wasan, A. D., Butler, S. F., Budman, S. H., Fernandez, K., Weiss, R. D., Greenfield, S. F., & Jamison, R. N. (2009) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e318193a6c4 · Cited by 109 · see citing works
Gender Differences in Prevalence of Substance Use Disorders among Individuals with Lifetime Exposure to Substances: Results from a Large Representative Sample
Lev‐Ran, S., Strat, Y. L., Imtiaz, S., Rehm, J. T., & Foll, B. L. (2013) · American Journal on Addictions · doi:10.1111/j.1521-0391.2013.00321.x · Cited by 107 · see citing works
Mental health and music engagement: review, framework, and guidelines for future studies
Gustavson, D. E., Coleman, P. L., Iversen, J. R., MAES, H. H. M., Gordon, R. L., & Lense, M. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01483-8 · Cited by 126 · see citing works
Different lengths of times for progressions in adolescent substance involvement
Ridenour, T. A., Lanza, S. T., Donny, E. C., & Clark, D. B. (2006) · Addictive Behaviors · doi:10.1016/j.addbeh.2006.03.015 · Cited by 103 · see citing works
The P300 event-related brain potential as a neurobiological endophenotype for substance use disorders: a meta-analytic investigation
Euser, A. S., Arends, L. R., Evans, B. E., Greaves-Lord, K., Huizink, A. C., & Franken, I. H. A. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.09.002 · Cited by 100 · see citing works
Relation between cognitive distortions and neurobehavior disinhibition on the development of substance use during adolescence and substance use disorder by young adulthood: a prospective study
Kirisci, L., Tarter, R. E., Vanyukov, M. M., Reynolds, M., & Habeych, M. E. (2004) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2004.04.015 · Cited by 101 · see citing works
Neurobiological Processes in Adolescent Addictive Disorders
Schepis, T. S., Adinoff, B. H., & Rao, U. (2008) · American Journal on Addictions · doi:10.1080/10550490701756146 · Cited by 95 · see citing works
Revisiting the concepts of risk and protective factors for understanding the etiology and development of substance use and substance use disorders: implications for prevention
Sloboda, Z., Glantz, M. D., & Tarter, R. E. (2012) · Substance Use & Misuse · doi:10.3109/10826084.2012.663280 · Cited by 94 · see citing works
Self-citation
The etiologic, theory-based, ontogenetic hierarchical framework of alcohol use disorder: A translational systematic review of reviews.
Boness, C. L., Watts, A. L., Moeller, K. N., & Sher, K. J. (2021) · Psychological Bulletin · doi:10.1037/bul0000333 · Cited by 95 · see citing works
Moving Beyond Misuse and Diversion: The Urgent Need to Consider the Role of Iatrogenic Addiction in the Current Opioid Epidemic
Beauchamp, G. A., Winstanley, E. L., Ryan, S. A., & Lyons, M. S. (2014) · American Journal of Public Health · doi:10.2105/ajph.2014.302147 · Cited by 92 · see citing works
The impact of emotional stress early in life on adult voluntary ethanol intake-results of maternal separation in rats
Roman, E., & Nylander, I. (2005) · Stress · doi:10.1080/10253890500188666 · Cited by 92 · see citing works
Directional Effects of Anxiety and Depressive Disorders with Substance Use: a Review of Recent Prospective Research
Garey, L., Olofsson, H., Garza, T., Rogers, A. H., Kauffman, B. Y., & Zvolensky, M. J. (2020) · Current Addiction Reports · doi:10.1007/s40429-020-00321-z · Cited by 95 · see citing works
Measurement of the risk for substance use disorders: phenotypic and genetic analysis of an index of common liability
Vanyukov, M. M., Kirisci, L., Moss, L., Tarter, R. E., Reynolds, M. D., Maher, B. S., Kirillova, G. P., Ridenour, T., & Clark, D. B. (2009) · Behavior Genetics · doi:10.1007/s10519-009-9269-9 · Cited by 88 · see citing works
Restless Sleep and Variable Sleep Timing During Late Childhood Accelerate the Onset of Alcohol and Other Drug Involvement
Hasler, B. P., Kirisci, L., & Clark, D. B. (2016) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2016.77.649 · Cited by 87 · see citing works
Common and drug-specific genetic influences on subjective effects to alcohol, tobacco and marijuana use
Haberstick, B. C., Zeiger, J. S., Corley, R. P., Hopfer, C. J., Stallings, M. C., Rhee, S. H., & Hewitt, J. K. (2010) · Addiction · doi:10.1111/j.1360-0443.2010.03129.x · Cited by 82 · see citing works
PTSD contributes to teen and young adult cannabis use disorders
Cornelius, J. R., Kirisci, L., Reynolds, M., Clark, D. B., Hayes, J., & Tarter, R. (2010) · Addictive Behaviors · doi:10.1016/j.addbeh.2009.09.007 · Cited by 80 · see citing works
“Logistic regression demonstrated that the development of CUDwas associatedwith PTSD, deviance of peers, the TLI, AfricanAmerican race, male gender, household SES, and being an offspring of a SUD+father.”
BackgroundInfluential
Evidence of increased activation underlying cognitive control in ecstasy and cannabis users
Roberts, G. M. P., & Garavan, H. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.04.192 · Cited by 80 · see citing works
Characterizing substance use and mental health profiles of cigar, blunt, and non-blunt marijuana users from the National Survey of Drug Use and Health
Cohn, A. M., Johnson, A. L., Ehlke, S. J., & Villanti, A. C. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.12.017 · Cited by 79 · see citing works
Liability to substance use disorders: 2. A measurement approach
Vanyukov, M. M., Kirisci, L., Tarter, R. E., Simkevitz, H. F., Kirillova, G. P., Maher, B. S., & Clark, D. B. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.08.003 · Cited by 77 · see citing works
Racial and ethnic trends and correlates of non-medical use of prescription opioids among adolescents in the United States 2004–2013
Vaughn, M. G., Nelson, E. J., Salas‐Wright, C. P., Qian, Z. M., & Schootman, M. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.11.003 · Cited by 76 · see citing works
Developmental trajectory classes in substance use disorder etiology.
Kirisci, L., Tarter, R. E., Mezzich, A. C., & Vanyukov, M. M. (2007) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.21.3.287 · Cited by 72 · see citing works
Meta-analysis of depression and substance use and impairment among cocaine users
Conner, K. R., Pinquart, M., & Holbrook, A. P. (2008) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.05.005 · Cited by 72 · see citing works
Population‐level patterns and mental health and substance use correlates of alcohol, marijuana, and tobacco use and co‐use in US young adults and adults: Results from the population assessment for tobacco and health
Cohn, A. M., Johnson, A. L., Rose, S. W., Pearson, J., Villanti, A. C., & Stanton, C. A. (2018) · American Journal on Addictions · doi:10.1111/ajad.12766 · Cited by 72 · see citing works
Do Pain Patients at High Risk for Substance Misuse Experience More Pain?: A Longitudinal Outcomes Study
Jamison, R. N., Link, C. L., & Marceau, L. D. (2009) · Pain Medicine · doi:10.1111/j.1526-4637.2009.00679.x · Cited by 70 · see citing works
Genetic Etiology of the Common Liability to Drug Dependence: Evidence of Common and Specific Mechanisms for DSM-IV Dependence Symptoms
Palmer, R., Button, T. M., Rhee, S., Corley, R., Young, S., Stallings, M., Hopfer, C., & Hewitt, J. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2011.12.015 · Cited by 68 · see citing works
Decline in Genetic Influence on th Co-Occurrence of Alcohol, Marijuana, and Nicotine Dependence Symptoms from Age 14 to 29?
Vrieze, S., Hicks, B. M., Iacono, W., & McGue, M. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.11081268 · Cited by 69 · see citing works
Subjective effects for alcohol, tobacco, and marijuana association with cross-drug outcomes
Zeiger, J. S., Haberstick, B. C., Corley, R. P., Ehringer, M. A., Crowley, T. J., Hewitt, J. K., Hopfer, C. J., Stallings, M. C., Young, S. E., & Rhee, S. H. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.02.014 · Cited by 65 · see citing works
Drug Addiction and Stress-Response Genetic Variability: Association Study in African Americans: Stress-Response Genes and Drug Addiction
Levran, O., Randesi, M., Li, Y., Rotrosen, J., Ott, J., Adelson, M., & Jeanne Kreek, M. (2014) · Annals of Human Genetics · doi:10.1111/ahg.12064 · Cited by 62 · see citing works
Underage alcohol use: summary of developmental processes and mechanisms: ages 16-20.
Brown, S. A., McGue, M., Maggs, J. L., Schulenberg, J. E., Hingson, R., Swartzwelder, S. H., Martin, C. S., Chung, T. A., Tapert, S. F., Sher, K. J., et al. (2009) · Europe PMC (PubMed Central) · Cited by 61 · see citing works
Index of the Transmissible Common Liability to Addiction: Heritability and Prospective Associations with Substance Abuse and Related Outcomes
Hicks, B. M., Iacono, W., & McGue, M. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2011.12.017 · Cited by 62 · see citing works
Detection of youth at high risk for substance use disorders: A longitudinal study.
Kirisci, L., Vanyukov, M. M., & Tarter, R. E. (2005) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.19.3.243 · Cited by 60 · see citing works
Prediction of Cannabis Use Disorder between Boyhood and Young Adulthood: Clarifying the Phenotype and Environtype
Kirisci, L., Tarter, R. E., Mezzich, A. C., Ridenour, T. A., Reynolds, M., & Vanyukov, M. M. (2009) · American Journal on Addictions · doi:10.1080/10550490802408829 · Cited by 58 · see citing works
Nicotinic acetylcholine receptors: upregulation, age‐related effects and associations with drug use
Melroy-Greif, W. E., Stitzel, J. A., & Ehringer, M. A. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12251 · Cited by 54 · see citing works
Predictors of onset of cannabis and other drug use in male young adults: results from a longitudinal study
Haug, S., López-Núñez, C., Becker, J., Gmel, G. E., & Schaub, M. P. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-1202 · Cited by 55 · see citing works
The MAOA promoter polymorphism, disruptive behavior disorders, and early onset substance use disorder: gene–environment interaction
Vanyukov, M. M., Maher, B. S., Devlin, B., Kirillova, G. P., Kirisci, L., Yu, L.-M., & Ferrell, R. E. (2007) · Psychiatric Genetics · doi:10.1097/ypg.0b013e32811f6691 · Cited by 56 · see citing works
Progression to regular heroin use: Examination of patterns, predictors, and consequences
Woodcock, E. A., Lundahl, L. H., Stoltman, J. J. K., & Greenwald, M. K. (2015) · Addictive Behaviors · doi:10.1016/j.addbeh.2015.02.014 · Cited by 53 · see citing works
Measuring Addiction Propensity and Severity: The Need for a New Instrument
Conway, K., Levy, J., Vanyukov, M., Chandler, R. K., Rutter, J., Swan, G., & Neale, M. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.03.011 · Cited by 51 · see citing works
Adolescents' self-defined tobacco use status, marijuana use, and tobacco dependence
Okoli, C. T. C., Richardson, C. G., Ratner, P. A., & Johnson, J. L. (2008) · Addictive Behaviors · doi:10.1016/j.addbeh.2008.05.008 · Cited by 52 · see citing works
The Genetically Informed Neurobiology of Addiction (GINA) model
Bogdan, R., Hatoum, A. S., Johnson, E. C., & Arpana Agrawal, A. (2022) · Nature reviews. Neuroscience · doi:10.1038/s41583-022-00656-8 · Cited by 54 · see citing works
The AVPR1A Gene and Substance Use Disorders: Association, Replication, and Functional Evidence
Maher, B. S., Vladimirov, V. I., Latendresse, S. J., Thiselton, D. L., McNamee, R. L., Kang, M., Bigdeli, T. B., Chen, X., Riley, B. P., Hettema, J. M., et al. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.02.023 · Cited by 49 · see citing works
Application of item response theory to quantify substance use disorder severity
Kirisci, L., Tarter, R. E., Vanyukov, M. M., Martin, C., Mezzich, A. C., & Brown, S. (2006) · Addictive Behaviors · doi:10.1016/j.addbeh.2006.03.033 · Cited by 48 · see citing works
Delay discounting differentiates pre-adolescents at high and low risk for substance use disorders based on family history
Dougherty, D. M., Charles, N. E., Mathias, C. W., Ryan, S. R., Olvera, R. L., Liang, Y., & Acheson, A. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.07.012 · Cited by 49 · see citing works
The Illustration-Based Assessment of Liability and EXposure to Substance use and Antisocial behavior © for Children
Ridenour, T. A., Clark, D. B., & Cottler, L. B. (2009) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990902998715 · Cited by 47 · see citing works
THC and CBD: Villain versus Hero? Insights into Adolescent Exposure
Pintori, N., Caria, F., Luca, M. A. D., & Miliano, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065251 · Cited by 48 · see citing works
Heritability of P300 amplitude development from adolescence to adulthood
Carlson, S. R., & Iacono, W. G. (2006) · Psychophysiology · doi:10.1111/j.1469-8986.2006.00450.x · Cited by 46 · see citing works
Menthol tobacco use is correlated with mental health symptoms in a national sample of young adults: implications for future health risks and policy recommendations
Cohn, A. M., Johnson, A. L., Hair, E. C., Rath, J. M., & Villanti, A. C. (2016) · Tobacco Induced Diseases · doi:10.1186/s12971-015-0066-3 · Cited by 45 · see citing works
Patterns of the co‐use of alcohol, marijuana, and emerging tobacco products in a national sample of young adults
Cohn, A. M., Johnson, A. L., Rath, J. M., & Villanti, A. C. (2016) · American Journal on Addictions · doi:10.1111/ajad.12456 · Cited by 44 · see citing works
Assessment of risk for substance use disorder consequent to consumption of illegal drugs: Psychometric validation of the neurobehavior disinhibition trait.
Mezzich, A. C., Tarter, R. E., Feske, U., Kirisci, L., McNamee, R. L., & Day, B. (2007) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.21.4.508 · Cited by 43 · see citing works
Common liability to drug addictions: Theory, research, practice
Vanyukov, M. M., & Ridenour, T. A. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.01.005 · Cited by 42 · see citing works
Identifying Childhood Characteristics that Underlie Pre-Morbid Risk for Substance Use Disorders: Socialization and Boldness
Hicks, B. M., Iacono, W., & McGue, M. (2013) · Development and Psychopathology · doi:10.1017/s0954579413000862 · Cited by 40 · see citing works
Testosterone Levels and Sexual Maturation Predict Substance Use Disorders in Adolescent Boys: A Prospective Study
Reynolds, M., Tarter, R. E., Kirisci, L., Kirillova, G. P., Brown, S., Clark, D. B., & Gavaler, J. S. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.008 · Cited by 39 · see citing works
Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence
Sun, Y., Chang, S., Liu, Z., Zhang, L., Wang, F., Yue, W., Sun, H., Ni, Z., Chang, X., Zhang, Y., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0497-y · Cited by 38 · see citing works
Does the “gateway” sequence increase prediction of cannabis use disorder development beyond deviant socialization? Implications for prevention practice and policy
Tarter, R. E., Kirisci, L., Mezzich, A. C., Ridenour, T. A., Fishbein, D. H., Horner, M. S., Reynolds, M., Kirillova, G. P., & Vanyukov, M. M. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.01.015 · Cited by 35 · see citing works
Could a continuous measure of individual transmissible risk be useful in clinical assessment of substance use disorder? Findings from the National Epidemiological Survey on Alcohol and Related Conditions
Ridenour, T. A., Kirisci, L., Tarter, R. E., & Vanyukov, M. M. (2011) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2011.05.018 · Cited by 32 · see citing works
Changes in Drug Use During Young Adulthood: The Effects of Parent Alcoholism and Transition Into Marriage.
Flora, D. B., & Chassin, L. (2005) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.19.4.352 · Cited by 32 · see citing works
A Longitudinal Examination of the Relationships between Childhood Maltreatment and Patterns of Adolescent Substance Use among High‐Risk Adolescents
Shin, S. H. (2012) · American Journal on Addictions · doi:10.1111/j.1521-0391.2012.00255.x · Cited by 31 · see citing works
Explaining Excessive Weight Gain during Early Recovery from Addiction
Gottfredson, N. C., & Sokol, R. L. (2018) · Substance Use & Misuse · doi:10.1080/10826084.2018.1536722 · Cited by 31 · see citing works
Comorbidity and temporal relations of alcohol and cannabis use disorders from youth through adulthood
Duncan, S. C., Gau, J. M., Farmer, R. F., Seeley, J. R., Kosty, D. B., & Lewinsohn, P. M. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.01.025 · Cited by 36 · see citing works
Dysregulation as a correlate of cannabis use and problem use
Lopez-Vergara, H. I., Jackson, K. M., Meshesha, L. Z., & Metrik, J. (2019) · Addictive Behaviors · doi:10.1016/j.addbeh.2019.03.010 · Cited by 29 · see citing works
Novel Biological Insights Into the Common Heritable Liability to Substance Involvement: A Multivariate Genome-wide Association Study
Schoeler, T., Baldwin, J. R., Allegrini, A. G., Barkhuizen, W., McQuillin, A., Pirastu, N., Kutalik, Z., & Pingault, J. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.07.027 · Cited by 25 · see citing works
Onset, Comorbidity, and Predictors of Nicotine, Alcohol, and Marijuana Use Disorders Among North American Indigenous Adolescents
Hautala, D. S., Sittner, K. J., & Walls, M. L. (2018) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-018-0500-0 · Cited by 28 · see citing works
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Liability to substance use disorders: 2. A measurement approach
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Measurement of the risk for substance use disorders: phenotypic and genetic analysis of an index of common liability
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Authors: Vanyukov, M. M., Tarter, R. E., Kirisci, L., Kirillova, G. P., Maher, B. S., & Clark, D. B.
Affiliations: University of Pittsburgh (US)
Corresponding author: Vanyukov, Michael M
ORCID: Vanyukov, Michael M
Tarter, Ralph E
Kirisci, Levent
Maher, Brion S
Clark, Duncan B
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2003-10
Volume: 27
Issue: 6
Pages: 507-515
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2003.08.002
OpenAlex: W2000690643
Cited by: 205
References: 92
Citations by year: 2026: 2 · 2025: 5 · 2024: 1 · 2023: 8 · 2022: 9 · 2021: 7 · 2020: 9 · 2019: 11 · 2018: 13 · 2017: 6 · 2016: 9 · 2015: 15 · 2014: 13 · 2013: 9 · 2012: 22
FWCI: 1.05
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01da011922-05)
National Institute on Alcohol Abuse and Alcoholism (R01AA011637, K02AA000291, K02-AA00291)
National Institute on Drug Abuse (R01-DA011922, P50DA005605)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
Keywords: substance use disorders, latent traits, genetic susceptibility, environmental risk factors, biochemical factors, psychological factors
MeSH terms: Brain Chemistry, Disease Susceptibility, Humans, Phenotype, Risk Factors, Sex Factors, Social Environment, Causality, Precipitating Factors, Substance-Related Disorders, Genetic Predisposition to Disease

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Liability to substance use disorders: 1. Common mechanisms and manifestations

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