Cited by 257Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and SenescenceAging and Gerontology Research

Recent results: Biomarkers of aging

Johnson, Thomas E.·2006·Experimental Gerontology

Abstract

This communication reviews recent papers attempting to identify Biomarkers of Aging (BoA). A BoA is a biological parameter that will predict functional capability at some later age. Few, if any, BoA have been found and this review describes the recent search for BoA. Among others that have been put forward are IL6 and other markers of inflammation, allostatic load, and corticosterone, which have been described primarily in humans. Work in model systems as well as theoretical work are also reviewed.

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Crossref · 10.1016/j.exger.2006.09.006

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  • Elevated IL-6 is a stable indicator of poor COVID-19 outcomes and is among the most reliable ageing parameters.

    “elevated IL-6 has been an especially stable indicator of poor outcomes in patients with COVID-19, and studies have demonstrated that IL-6 is also among the most reliable ageing parameters69.”

    From SARS-CoV-2, COVID-19 and the aging immune system (2021) · cites this paper as [69]

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Authors
Johnson, T. E.
Affiliations
University of Colorado Boulder (US)
Corresponding author
Johnson, Thomas E.
Venue
Experimental Gerontology
Publisher
Elsevier BV
Published
2006-12
Volume
41
Issue
12
Pages
1243-1246
ISSN
0531-5565 (ISSN-L)
OpenAlex
W2134041267
Cited by
257
References
21
Citations by year
2026: 5 · 2025: 6 · 2024: 12 · 2023: 15 · 2022: 17 · 2021: 22 · 2020: 15 · 2019: 14 · 2018: 12 · 2017: 11 · 2016: 11 · 2015: 18 · 2014: 9 · 2013: 11 · 2012: 16
FWCI
3.29
Type
journal article
Language
en
Open access
closed
Locations
  • Experimental Gerontology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
  • Health Sciences › Medicine › Physiology › Telomeres, Telomerase, and Senescence
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Aging and Gerontology Research
Keywords
aging biomarkers, aging, functional capacity, interleukin-6, inflammation, allostatic load, corticosterone, model organisms
MeSH terms
Aged, Aging, Animals, Cognition Disorders, DNA, Mitochondrial, Humans, Socioeconomic Factors, Biomarkers, Interleukin-6, Cytokines, Telomere, Caenorhabditis elegans, Risk Assessment, Models, Animal

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