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Cited by 567

The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.

microRNA biogenesis and function in plants

Open access
Chen, Xuemei·2005·FEBS Letters

Abstract

A microRNA (miRNA) is a 21–24 nucleotide RNA product of a non‐protein‐coding gene. Plants, like animals, have a large number of miRNA‐encoding genes in their genomes. The biogenesis of miRNAs in Arabidopsis is similar to that in animals in that miRNAs are processed from primary precursors by at least two steps mediated by RNAse III‐like enzymes and that the miRNAs are incorporated into a protein complex named RISC. However, the biogenesis of plant miRNAs consists of an additional step, i.e., the miRNAs are methylated on the ribose of the last nucleotide by the miRNA methyltransferase HEN1. The high degree of sequence complementarity between plant miRNAs and their target mRNAs has facilitated the bioinformatic prediction of miRNA targets, many of which have been subsequently validated. Plant miRNAs have been predicted or confirmed to regulate a variety of processes, such as development, metabolism, and stress responses. A large category of miRNA targets consists of genes encoding transcription factors that play important roles in patterning the plant form.

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Metadata

Authors
Chen, X.
Venue
FEBS Letters
Publisher
Wiley
Published
2005-08-09
Volume
579
Issue
26
Pages
5923-5931
ISSN
  • 0014-5793 (ISSN-L)
  • 1873-3468
OpenAlex
W2017020642
Cited by
567
References
109
FWCI
29.06
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: microRNA biogenesis and function in plants. https://app.cochat.ai/papers/10.1016/j.febslet.2005.07.071
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Chen, X. (2005). microRNA biogenesis and function in plants. FEBS Letters. https://doi.org/10.1016/j.febslet.2005.07.071

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.