The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Dynamics of Cdc42 network embodies a Turing‐type mechanism of yeast cell polarity
Open accessAbstract
Complex biochemical networks can be understood by identifying their principal regulatory motifs and mode of action. We model the early phase of budding yeast cellular polarization and show that the biochemical processes in the presumptive bud site comprise a Turing‐type mechanism. The roles of the prototypical activator and substrate are played by GTPase Cdc42 in its active and inactive states, respectively. We demonstrate that the nucleotide cycling of Cdc42 converts cellular energy into a stable cluster of activated Cdc42. This energy drives a continuous membrane‐cytoplasmic exchange of the cluster components to counteract diffusive spread of the cluster. This exchange explains why only one bud forms per cell cycle, because the winner‐takes‐all competition of candidate sites inevitably selects a single site.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The chemical basis of morphogenesis
Turing, A. M. (1952) · Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences · doi:10.1098/rstb.1952.0012 · Cited by 11,733
Global analysis of protein expression in yeast
Ghaemmaghami, S., Huh, W.-K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., & Weissman, J. S. (2003) · Nature · doi:10.1038/nature02046 · Cited by 3,750
Mathematical handbook for scientists and engineers
Korn, G. A. (1961) · Cited by 3,428
RHO GTPASES: Biochemistry and Biology
Jaffe, A. B., & Hall, A. (2005) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.020604.150721 · Cited by 3,009
Thermodynamic Theory of Structure, Stability and Fluctuations
Glansdorff, P., Prigogine, I., & Hill, R. N. (1973) · American Journal of Physics · doi:10.1119/1.1987158 · Cited by 2,973
Rabs and their effectors: achieving specificity in membrane traffic
Grosshans, B. L., Ortiz, D., & Novick, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601617103 · Cited by 1,005
Feinberg, M. (1987) · Chemical Engineering Science · doi:10.1016/0009-2509(87)80099-4 · Cited by 744
Ayscough, K. R., Stryker, J., Pokala, N., Sanders, M., Crews, P., & Drubin, D. G. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.2.399 · Cited by 735
Differential Localization of Rho Gtpases in Live Cells
Michaelson, D., Silletti, J., Murphy, G., D'Eustachio, P., Rush, M., & Philips, M. R. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.1.111 · Cited by 679
Roles of Rho-family GTPases in cell polarisation and directional migration
Fukata, M., Nakagawa, M., & Kaibuchi, K. (2003) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(03)00097-8 · Cited by 485
Cited by
Signalling ballet in space and time
Kholodenko, B. N., Hancock, J. F., & Kolch, W. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2901 · Cited by 614
Houk, A. R., Jilkine, A., Mejean, C. O., Boltyanskiy, R., Dufresne, E. R., Angenent, S. B., Altschuler, S. J., Wu, L. F., & Weiner, O. D. (2012) · Cell · doi:10.1016/j.cell.2011.10.050 · Cited by 565
Endocytosis and signaling: Cell logistics shape the eukaryotic cell plan
Sigismund, S., Confalonieri, S., Ciliberto, A., Polo, S., Scita, G., & Di Fiore, P. P. (2012) · Physiological Reviews · doi:10.1152/physrev.00005.2011 · Cited by 338
Cell Polarization and Cytokinesis in Budding Yeast
Bi, E., & Park, H.-O. (2012) · Genetics · doi:10.1534/genetics.111.132886 · Cited by 305
Bement, W. M., Leda, M., Moe, A. M., Kita, A. M., Larson, M. E., Golding, A. E., Pfeuti, C., Su, K.-C., Miller, A. L., Goryachev, A. B., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3251 · Cited by 299
Self-citation
Metadata
- Authors
- Goryachev, A. B., & Pokhilko, A. V.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2008-03-31
- Volume
- 582
- Issue
- 10
- Pages
- 1437-1443
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W1985482228
- Cited by
- 327
- References
- 58
- FWCI
- 5.71
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Dynamics of Cdc42 network embodies a Turing‐type mechanism of yeast cell polarity. https://app.cochat.ai/papers/10.1016/j.febslet.2008.03.029
- The paper
- Goryachev, A. B., & Pokhilko, A. V. (2008). Dynamics of Cdc42 network embodies a Turing‐type mechanism of yeast cell polarity. FEBS Letters. https://doi.org/10.1016/j.febslet.2008.03.029
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
