Cited by 234Autophagy in Disease and TherapyCellular transport and secretionCalcium signaling and nucleotide metabolism

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Regulation of autophagy by phosphatidylinositol 3‐phosphate

Burman, Chloe, Ktistakis, Nicholas T.·2010·FEBS Letters

DOI 10.1016/j.febslet.2010.01.011

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Abstract

The simple phosphoinositide phosphatidylinositol 3‐phosphate (PI(3)P) has been known to have important functions in endocytic and phagocytic traffic, and to be required for the autophagic pathway. In all of these settings, PI(3)P appears to create platforms that serve to recruit specific effectors for membrane trafficking events. In autophagy, PI(3)P may form the platform for autophagosome biogenesis.

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Authors: Burman, C., & Ktistakis, N. T.
Affiliations: Babraham Institute (GB)
Corresponding author: Ktistakis, Nicholas T.
ORCID: Ktistakis, Nicholas T.
Venue: FEBS Letters
Publisher: Wiley
Published: 2010-01-13
Volume: 584
Issue: 7
Pages: 1302-1312
ISSN: 0014-5793 (ISSN-L)
1873-3468
DOI: 10.1016/j.febslet.2010.01.011
OpenAlex: W2031697171
Cited by: 234
References: 115
Citations by year: 2026: 10 · 2025: 10 · 2024: 10 · 2023: 17 · 2022: 14 · 2021: 17 · 2020: 14 · 2019: 23 · 2018: 9 · 2017: 21 · 2016: 28 · 2015: 10 · 2014: 11 · 2013: 10 · 2012: 16
FWCI: 1.45
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: FEBS Letters (publishedVersion)
PubMed (publishedVersion)
Funders: Biotechnology and Biological Sciences Research Council (BBS/E/B/00001221)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Calcium signaling and nucleotide metabolism
Keywords: autophagy, phosphatidylinositol 3-phosphate, autophagosome formation, membrane trafficking, endocytosis, phagocytosis, phosphoinositide signaling
MeSH terms: Animals, Autophagy, Humans, Phagocytosis, Signal Transduction, Protein Structure, Tertiary, Phosphatidylinositol Phosphates, Phosphatidylinositol 3-Kinases

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Regulation of autophagy by phosphatidylinositol 3‐phosphate

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