The DOI matches its Crossref record; 150 of the 150 references it cites were found in a registry or an index.
Enzymatic hydrolysis and microbial fermentation: The most favorable biotechnological methods for the release of bioactive peptides
Open accessAbstract
Bioactive peptides are biomolecules derived from proteins. They contain anywhere from 2 to 20 amino acids and have different bioactivities. For example, they have antihypertensive activity, antioxidant activity, antimicrobial activity, etc. However, bioactive peptides are encrypted and inactive in the parental protein, so it is necessary to release them to show their bioactivity. For this, there are different methods, where biotechnological methods are highly favorable, highlighting enzymatic hydrolysis and microbial fermentation. The choice of the method to be used depends on different factors, which is why it is essential to know about the process, its principle, and its advantages and disadvantages. The process of peptide release is critical to generate various peptide sequences, which will produce different biological effects in the hydrolysate. This review focuses on providing extensive information on the enzymatic method and microbial fermentation to facilitate selecting the method that provides the most benefits.
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Cites
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Cited by
Ali, S. S., Al-Tohamy, R., Al-Zahrani, M., Schagerl, M., Kornaros, M., & Sun, J. (2025) · Microbial Cell Factories · doi:10.1186/s12934-025-02685-1 · Cited by 88
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Extraction methods, encapsulation techniques, and health benefits of astaxanthin
Panagiotakopoulos, I., & Nasopoulou, C. (2024) · Sustainability · doi:10.3390/su162410859 · Cited by 33
Microalgae-Derived Peptides: Exploring Bioactivities and Functional Food Innovations
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Metadata
- Authors
- Cruz-Casas, D. E., Aguilar, C. N., Ascacio-Valdés, J. A., Rodríguez-Herrera, R., Chávez-González, M. L., & Flores-Gallegos, A. C.
- Venue
- Food Chemistry: Molecular Sciences
- Publisher
- Elsevier BV
- Published
- 2021-12
- Volume
- 3
- Pages
- 100047
- ISSN
- 2666-5662 (ISSN-L)
- OpenAlex
- W3208158831
- Cited by
- 363
- References
- 150
- FWCI
- 13.28
- Type
- journal article
- Language
- en
- Open access
- gold
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- Cruz-Casas, D. E., Aguilar, C. N., Ascacio-Valdés, J. A., Rodríguez-Herrera, R., Chávez-González, M. L., & Flores-Gallegos, A. C. (2021). Enzymatic hydrolysis and microbial fermentation: The most favorable biotechnological methods for the release of bioactive peptides. Food Chemistry: Molecular Sciences. https://doi.org/10.1016/j.fochms.2021.100047
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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