Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets

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Cellular senescence in liver fibrosis: Implications for age-related chronic liver diseases

Udomsinprasert, W., Sobhonslidsuk, A., Jittikoon, J., Honsawek, S., & Chaikledkaew, U. (2021) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2021.1992385 · Cited by 40 · see citing works

H3K18 lactylation accelerates liver fibrosis progression through facilitating SOX9 transcription.

Wu, S., Li, J., & Zhan, Y.-T. (2024) · Experimental Cell Research · doi:10.1016/j.yexcr.2024.114135 · Cited by 42 · see citing works

Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells

Li, Z.-B., Jiang, L., Ni, J., Xu, Y.-H., Liu, F., Liu, W., Wang, S.-G., Liu, Z., & Wang, C.-Y. (2023) · Acta Pharmacologica Sinica · doi:10.1038/s41401-022-01044-9 · Cited by 36 · see citing works

Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2

Ban, D., Hua, S., Zhang, W., Shen, C., Miao, X., & Liu, W. (2019) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-019-0179-4 · Cited by 36 · see citing works

The Phenylethanol Glycoside Liposome Inhibits PDGF-Induced HSC Activation via Regulation of the FAK/PI3K/Akt Signaling Pathway

Zhang, S.-L., Ma, L., Zhao, J., You, S., Ma, X., Ye, X., & Liu, T. (2019) · Molecules · doi:10.3390/molecules24183282 · Cited by 35 · see citing works

S100 Proteins in Fatty Liver Disease and Hepatocellular Carcinoma

Delangre, E., Oppliger, E., Berkcan, S., Gjorgjieva, M., de Sousa, M. C., & Foti, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911030 · Cited by 34 · see citing works

Evaluation of Pancreatic Fibrosis Grading by Multiparametric Quantitative Magnetic Resonance Imaging

Liu, C., Shi, Y., Lan, G., Xu, Y., & Yang, F. (2021) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.27626 · Cited by 33 · see citing works

Sequential delivery for hepatic fibrosis treatment based on carvedilol loaded star-like nanozyme

Lü, Q., Zhou, Y., Xu, M., Liang, X., Jing, H., Wang, X., & Li, N. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.11.033 · Cited by 32 · see citing works

Therapeutic implications of targeting autophagy and TGF-β crosstalk for the treatment of liver fibrosis

Siapoush, S., Rezaei, R., Alavifard, H., Hatami, B., Zali, M. R., Vosough, M., Lorzadeh, S., Łoś, M., Baghaei, K., & Ghavami, S. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.121894 · Cited by 32 · see citing works

Ion Channels Orchestrate Pancreatic Ductal Adenocarcinoma Progression and Therapy

Hofschröer, V., Najder, K., Rugi, M., Bouazzi, R., Cozzolino, M., Arcangeli, A., Panyi, G., & Schwab, A. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.586599 · Cited by 31 · see citing works

Galectin-3 and Severity of Liver Fibrosis in Metabolic Dysfunction-Associated Fatty Liver Disease

Sotoudeheian, M. (2024) · Protein and Peptide Letters · doi:10.2174/0109298665301698240404061300 · Cited by 32 · see citing works

Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage

Jiang, Y., Hou, L., Dou, J., Xuan, M., Cui, Z., Lian, L., Nan, J., & Wu, Y. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.155145 · Cited by 29 · see citing works

Antifibrotic effect of methylated quercetin derivatives on TGFβ-induced hepatic stellate cells

Ganbold, M., Shimamoto, Y., Ferdousi, F., Tominaga, K., & Isoda, H. (2019) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2019.100678 · Cited by 28 · see citing works

Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation

Li, X., Chen, R., Kemper, S., & Brigstock, D. R. (2020) · Cells · doi:10.3390/cells9020290 · Cited by 28 · see citing works

Paeoniflorin modulates oxidative stress, inflammation and hepatic stellate cells activation to alleviate CCl4-induced hepatic fibrosis by upregulation of heme oxygenase-1 in mice

Wang, T., Zhou, X., Kuang, G., Jiang, R., Guo, X., Wu, S., Wan, J., & Yin, L. (2021) · Journal of Pharmacy and Pharmacology · doi:10.1093/jpp/rgaa042 · Cited by 28 · see citing works

Comparative analysis of various temporary computer-aided design/computer-aided manufacturing polymethyl methacrylate crown materials based on color stability, flexural strength, and surface roughness: An in vitro study

Shenoy, A. D., Rajaraman, V., & Maiti, S. (2022) · Journal of Advanced Pharmaceutical Technology amp Research · doi:10.4103/japtr.japtr_119_22 · Cited by 27 · see citing works

Serum chitinase-3-like protein 1 is a biomarker of liver fibrosis in patients with chronic hepatitis B in China

Jin, X., Fu, B., Wu, Z., Zheng, X., Hu, J., Jin, L., & Tang, L. (2020) · Hepatobiliary & pancreatic diseases international · doi:10.1016/j.hbpd.2020.05.009 · Cited by 26 · see citing works

Exosomal microRNA-618 derived from mesenchymal stem cells attenuate the progression of hepatic fibrosis by targeting Smad4

Sun, C., Shi, C., Duan, X., Zhang, Y., & Wang, B. (2022) · Bioengineered · doi:10.1080/21655979.2021.2023799 · Cited by 25 · see citing works

Bone marrow mesenchymal stem cells inhibit hepatic fibrosis via the AABR07028795.2/rno-miR-667-5p axis

Feng, Y., Li, Y., Xu, M., Meng, H., Dai, C., Yao, Z., & Lin, N. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-03069-7 · Cited by 25 · see citing works

Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis in rats: Possible role of SIRT1/Nrf2/HO-1 pathway

Abu-Risha, S. E.-S., Sokar, S. S., Elbohoty, H. R., & El‐Sisi, A. E. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.109750 · Cited by 26 · see citing works

Light-triggered NO-releasing nanoparticles for treating mice with liver fibrosis

Liang, H., Li, Z., Ren, Z., Jia, Q., Guo, L., Li, S., Zhang, H., Hu, S., Zhu, D., Shen, D., et al. (2020) · Nano Research · doi:10.1007/s12274-020-2833-6 · Cited by 25 · see citing works

Irisin Regulates the Functions of Hepatic Stellate Cells

Dong, H. N., Park, S. Y., Le, C. T., Choi, D.-H., & Cho, E.-H. (2020) · Endocrinology and Metabolism · doi:10.3803/enm.2020.658 · Cited by 23 · see citing works

Research progress of natural compounds in anti-liver fibrosis by affecting autophagy of hepatic stellate cells

Shu, Y., Liu, X., Huang, H., Wen, Q., & Shu, J. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06171-w · Cited by 23 · see citing works

MicroRNA-195-3p promotes hepatic stellate cell activation and liver fibrosis by suppressing PTEN expression

Wang, A., Bu, F., Li, J., Zhang, Y., Jia, P., You, H., Wu, S., Wu, Y., Zhu, S., Huang, C. Z., et al. (2021) · Toxicology Letters · doi:10.1016/j.toxlet.2021.11.014 · Cited by 23 · see citing works

Clinical application of deep learning and radiomics in hepatic disease imaging: a systematic scoping review

Wang, L., Zhang, L., Jiang, B., Zhao, K., Zhang, Y., & Xie, X. (2022) · British Journal of Radiology · doi:10.1259/bjr.20211136 · Cited by 23 · see citing works

Advantages and challenges in nanomedicines for chronic liver diseases: A hepatologist's perspectives

Ezhilarasan, D. (2021) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173832 · Cited by 22 · see citing works

Interaction of non‑parenchymal hepatocytes in the process of hepatic fibrosis (Review)

Cheng, Q.-N., Yang, X. Y., Wu, J., Ai, W., & Ni, Y. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12003 · Cited by 22 · see citing works

Possible roles of Golgi protein-73 in liver diseases

Liu, M., Huang, L. H., Wu, J., Zhang, H., Ai, W., & Zhang, R. (2022) · Annals of Hepatology · doi:10.1016/j.aohep.2022.100720 · Cited by 22 · see citing works

Relaxin in hepatic fibrosis: What is known and where to head?

Ezhilarasan, D. (2021) · Biochimie · doi:10.1016/j.biochi.2021.06.001 · Cited by 21 · see citing works

Traf2 and NCK Interacting Kinase Is a Critical Regulator of Procollagen I Trafficking and Hepatic Fibrogenesis in Mice

Buchl, S. C., Hanquier, Z., Haak, A. J., Thomason, Y. M., Huebert, R. C., Shah, V. H., & Maiers, J. L. (2021) · Hepatology Communications · doi:10.1002/hep4.1835 · Cited by 20 · see citing works

α-Lipoic acid modulates liver fibrosis: A cross talk between TGF-β1, autophagy, and apoptosis

El-Maadawy, W. H., Hammam, O. A., el-Din, S. H. S., & El-Lakkany, N. M. (2019) · Human & Experimental Toxicology · doi:10.1177/0960327119891212 · Cited by 19 · see citing works

Preclinical liver toxicity models: Advantages, limitations and recommendations

Ezhilarasan, D., Karthikeyan, S., Najimi, M., Paramasivan, V., Bhavani, G., & Rani, M. J. (2024) · Toxicology · doi:10.1016/j.tox.2024.154020 · Cited by 19 · see citing works

Retinoids in Stellate Cells: Development, Repair, and Regeneration

Carmona, R., Barrena, S., & Muñoz‐Chápuli, R. (2019) · Journal of Developmental Biology · doi:10.3390/jdb7020010 · Cited by 18 · see citing works

Vitamin A - modified Betulin polymer micelles with hepatic targeting capability for hepatic fibrosis protection

Liu, X., Li, D., Li, T. Y., Wu, Y., Piao, J. S., & Piao, M. G. (2022) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2022.106189 · Cited by 18 · see citing works

Regulation of SIRT1-TLR2/TLR4 pathway in cell communication from macrophages to hepatic stellate cells contribute to alleviates hepatic fibrosis by Luteoloside

Xiu, M.-X., Zhao, Y., Wang, X., Yuan, S., Qin, B.-F., Sun, J., Cui, L., & Song, J. (2022) · Acta Histochemica · doi:10.1016/j.acthis.2022.151989 · Cited by 19 · see citing works

Unraveling the pathophysiologic role of galectin‐3 in chronically injured liver

Ezhilarasan, D. (2023) · Journal of Cellular Physiology · doi:10.1002/jcp.30956 · Cited by 18 · see citing works

Vanillic acid alleviates liver fibrosis through inhibiting autophagy in hepatic stellate cells via the MIF/CD74 signaling pathway

Qin, L., Tan, J., Lv, X., & Zhang, J. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115673 · Cited by 18 · see citing works

GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition

Bestion, E., Jílková, Z. M., Mège, J., Novello, M., Kurma, K., Pour, S. T. A., Lalmanach, G., Vanderlynden, L., Fizanne, L., Bassissi, F., et al. (2020) · Therapeutic Advances in Chronic Disease · doi:10.1177/2040622320942042 · Cited by 18 · see citing works

Metabolic Alterations in Spheroid-Cultured Hepatic Stellate Cells

Fujisawa, K., Takami, T., Sasai, N., Matsumoto, T., Yamamoto, N., & Sakaida, I. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21103451 · Cited by 18 · see citing works

Deciphering the possible reciprocal loop between hepatic stellate cells and cancer cells in the tumor microenvironment of the liver

Ezhilarasan, D., & Najimi, M. (2023) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2022.103902 · Cited by 17 · see citing works

Nanoparticle formulation of mycophenolate mofetil achieves enhanced efficacy against hepatocellular carcinoma by targeting tumour‐associated fibroblast

Yang, Z., Zhang, L., Zhu, H. H., Zhou, K., Wang, H., Wang, Y., Su, R., Guo, D., Zhou, L., Xu, X., et al. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16434 · Cited by 17 · see citing works

Hepatocellular Interactions of Potential Nutraceuticals in the Management of Inflammatory NAFLD

Ezhilarasan, D., & Kulanthaivel, L. (2024) · Cell Biochemistry and Function · doi:10.1002/cbf.4112 · Cited by 17 · see citing works

Vaspin attenuates steatosis-induced fibrosis via GRP78 receptor by targeting AMPK signaling pathway

Abdolahi, A., Vahabzadeh, Z., Izadpanah, E., & Moloudi, M. R. (2022) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-021-00852-7 · Cited by 16 · see citing works

Adoptive transfer of regulatory T cells stimulated by Allogeneic Hepatic Stellate Cells mitigates liver injury in mice with concanavalin A-induced autoimmune hepatitis

Huang, H., & Deng, Z. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.02.147 · Cited by 16 · see citing works

Identification of linderalactone as a natural inhibitor of SHP2 to ameliorate CCl4-induced liver fibrosis

Zhang, Y., Cai, B., Li, Y., Xu, Y. J., Wang, Y., Zheng, L., Zheng, X., Yin, L., Chen, G., Wang, Y., et al. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1098463 · Cited by 15 · see citing works

Role of sirtuins in liver diseases

Ezhilarasan, D., & Najimi, M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814118-2.00005-7 · Cited by 15 · see citing works

Tripartite motif protein 52 (TRIM52) promoted fibrosis in LX‐2 cells through PPM1A‐mediated Smad2/3 pathway

Zhou, J., Lan, Q., Li, W., Yang, L., You, J., Zhang, Y., & Ni, W. (2019) · Cell Biology International · doi:10.1002/cbin.11206 · Cited by 15 · see citing works

Effects of autophagy inhibition by chloroquine on hepatic stellate cell activation in CCl4‐induced acute liver injury mouse model

Le, T. V., Dinh, N. B. T., Dang, T. M., Phan, N. L.-C., Dang, L. T. T., Grassi, G., Holterman, A., Le, H. M., & Truong, N. H. (2021) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.15726 · Cited by 14 · see citing works

Estrogen receptor 1 signaling in hepatic stellate cells designates resistance to liver fibrosis

Li, T., Wang, G., Zhao, H., Liu, F., Deng, Z., Chen, D., Zhou, X., Cao, Y., Fu, W., Zhang, H., et al. (2025) · Cell Discovery · doi:10.1038/s41421-025-00783-3 · Cited by 13 · see citing works

Unlocking the potential of Mesenchymal stem cells in liver Fibrosis: Insights into the impact of autophagy and aging

Tao, H., Liu, Q., Zeng, A., & Song, L. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110497 · Cited by 13 · see citing works

Stress and Liver Fibrogenesis

Hanquier, Z., Misra, J., Baxter, R., & Maiers, J. L. (2023) · American Journal Of Pathology · doi:10.1016/j.ajpath.2023.06.006 · Cited by 13 · see citing works

Flavonoids-based nanomedicines for the treatment of liver fibrosis: A recent progress

Harini, K. S., & Ezhilarasan, D. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105467 · Cited by 13 · see citing works

DZNep, an inhibitor of the histone methyltransferase EZH2, suppresses hepatic fibrosis through regulating miR-199a-5p/SOCS7 pathway

Ding, R., Zheng, J., Li, N., Cheng, Q., Zhu, M., Wang, Y., Zhou, X., Zhang, Z., & Shi, G. (2021) · PeerJ · doi:10.7717/peerj.11374 · Cited by 13 · see citing works

Role of ferroptosis in fibrosis diseases

Sun, Z., Zou, X., Bao, M., Huang, Z., Lou, Y., Zhang, Y., & Huang, P. C. (2023) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2023.04.024 · Cited by 14 · see citing works

Discovery and evaluation of phenacrylanilide derivatives as novel potential anti-liver fibrosis agents

Lin, Y., Xue, T., Su, X., Liu, Z., Liu, H., Tan, Z., Gan, C., Xie, Y., & Ye, T. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114685 · Cited by 12 · see citing works

CaM/CaMKII mediates activation and proliferation of hepatic stellate cells regulated by ASIC1a

Liu, H., Lu, W., Hong, H.-Q., Li, M., Ye, M.-P., Rao, Q.-F., Kong, J.-L., Luan, S., Huang, Y., Hu, Q., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.996667 · Cited by 12 · see citing works

Roxarsone inhibits hepatic stellate cell activation and ameliorates liver fibrosis by blocking TGF-β1/Smad signaling pathway

Li, T., Su, X., Chen, L.-L., Zhang, W., Zhang, J., Wang, Y., & Xu, W. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109527 · Cited by 12 · see citing works

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

Setyawati, D. R., Sekaringtyas, F. C., Pratiwi, R. D., Rosyidah, A., Azhar, R., Gustini, N., Syahputra, G., Rosidah, I., Mardliyati, E., Tarwadi, et al. (2024) · Beilstein Journal of Nanotechnology · doi:10.3762/bjnano.15.89 · Cited by 12 · see citing works

Lead compounds with the potentials for the treatment of chronic liver diseases

Ezhilarasan, D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817890-4.00012-3 · Cited by 12 · see citing works

Nanomedicine for Hepatic Fibrosis

Ezhilarasan, D., & Rajeshkumar, S. (2020) · Springer eBooks · doi:10.1007/978-981-15-0391-7_2 · Cited by 12 · see citing works

IOX1 protects from TGF‑β induced fibrosis in LX‑2 cells via the regulation of extracellular matrix protein expression

Tian, T., Xie, R., Ding, K., Han, B., Yang, Q., & Yang, X. Y. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.9611 · Cited by 11 · see citing works

Hsp47 acts as a bridge between NLRP3 inflammasome and hepatic stellate cells activation in arsenic-induced liver fibrosis

Yuan, W., Qiu, T., Yao, X., Wu, C., Shi, Y., Wang, N., Zhang, J., Jiang, L., Liu, X., Yang, G., et al. (2022) · Toxicology Letters · doi:10.1016/j.toxlet.2022.07.816 · Cited by 11 · see citing works

UEG Week 2019 Poster Presentations

Jaeger, M.-C., Guiraud, L., Rolland, C., Rolland, C., Belot, A., Sebbag, M., Bermúdez‐Humarán, L. G., Langella, P., Vergnolle, N., & Deraison, C. (2019) · United European Gastroenterology Journal · doi:10.1177/2050640619854671 · Cited by 11 · see citing works

The effect of vitamin D supplementation on the progression of fibrosis in patients with chronic liver disease

Chen, T., Zuo, X., Wang, S., Yu, P., Yuan, J., Wei, S., Chen, J., Sun, Y., Gao, Y., & Li, X. (2020) · Medicine · doi:10.1097/md.0000000000020296 · Cited by 9 · see citing works

Anti-fibrotic effect of intravenous umbilical cord-derived mesenchymal stem cells (UC-MSCs) injection in experimental rats induced liver fibrosis

Sungkar, T., Putra, A. B., Lindarto, D., & Sembiring, R. J. (2020) · Medicinski Glasnik · doi:10.17392/1211-21 · Cited by 9 · see citing works

Lagerstroemia speciosa (L.) Pers., ethanolic leaves extract attenuates dapsone-induced liver inflammation in rats

Singh, T. R., & Ezhilarasan, D. (2021) · Drug and Chemical Toxicology · doi:10.1080/01480545.2021.1945079 · Cited by 9 · see citing works

11β‑hydroxysteroid dehydrogenase‑1 is associated with the activation of hepatic stellate cells in the development of hepatic fibrosis

Xiao, W., Lu, M.-H., Rong, P., Zhang, H., Gong, J., Peng, Y., Gong, H., & Liu, Z. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.11423 · Cited by 8 · see citing works

miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα

Ma, H., Wang, X., Liu, X., Wang, C., Gao, X., & Niu, J. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.841248 · Cited by 8 · see citing works

Extraction, characterization, and anticancer potential of extracellular polymeric substances from marine actinobacteria of Streptomyces species

Noufal, Z. M., Sivaperumal, P., & Elumalai, P. (2022) · Journal of Advanced Pharmaceutical Technology amp Research · doi:10.4103/japtr.japtr_331_22 · Cited by 8 · see citing works

The potential health benefits and mechanisms of sesame lignans in age-related diseases

Li, Y., Chang, Y., Zhang, Y., Tu, W., Xu, F., Zhang, L., Wang, X., & Wang, L. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105360 · Cited by 7 · see citing works

Advances in antituberculosis drug-induced liver injury: Molecular mechanisms, genetic insights, and emerging animal-free prediction models

Yang, R., Zhu, J., Jin, X., Li, Y., Wang, D., & Chao, J. (2025) · Toxicology · doi:10.1016/j.tox.2025.154359 · Cited by 9 · see citing works

Ginsenoside AD-2 Ameliorating Lipopolysaccharide-Induced Activation in HSC-T6 Cells and Carbon Tetrachloride-Induced Hepatic Fibrosis in Mice via Regulation of VD-VDR Axis

Chen, Y., Lin, L., Yang, C., Li, T., Li, Y., Wang, J., Wu, Y., Zhao, Y., & Su, G. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c06804 · Cited by 7 · see citing works

Mechanism of annexin A1/N-formylpeptide receptor regulation of macrophage function to inhibit hepatic stellate cell activation through Wnt/β-catenin pathway

Fan, J., Luo, N., Liu, G.-F., Xu, X., Li, S., & Lv, X. (2023) · World Journal of Gastroenterology · doi:10.3748/wjg.v29.i22.3422 · Cited by 7 · see citing works

A meritorious integrated medical regimen for hepatic fibrosis and its complications via the systematic review and meta-analysis for Dahuang Zhechong pill-based therapy

Ye, Z., Huang, Q., She, Y., Hu, Y., Wu, M., Qin, K., Li, L., Zhang, C., Zuo, X., Wei, A., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.920062 · Cited by 7 · see citing works

HO‐1: An emerging target in fibrosis

Lu, C., Liu, Y., Ren, F., Zhang, H., Hou, Y., Zhang, H., Chen, Z., & Du, X. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31465 · Cited by 6 · see citing works

New advances of nanozymes for the diagnosis and treatment of digestive system diseases (Review)

Xie, D., Xie, L., Fang, C., Du, Z., Cao, Z., Su, C., & Huo, Y. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5617 · Cited by 6 · see citing works

FAM3B activates hepatic stellate cells to accelerate hepatic fibrosis by promoting glucose metabolism

Wei, W., Lin, C., Luo, S., Huang, J., Hu, R.-T., Li, J., Ma, H., Wei, J.-Z., Wang, C., Lim, C.-S.-Y., et al. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152703 · Cited by 6 · see citing works

Periplaneta americana extract attenuates hepatic fibrosis progression by inhibiting collagen synthesis and regulating the TGF-β1/Smad signaling pathway

Chen, Y., Zhao, Y., Yuan, L., He, Y., Yang, Y., & Xiao, P. (2023) · Folia Histochemica et Cytobiologica · doi:10.5603/fhc.94457 · Cited by 6 · see citing works

Deciphering the toxicological role of Porphyromonas gingivalis derived endotoxins in liver diseases

Ezhilarasan, D. (2021) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2021.103755 · Cited by 6 · see citing works

Clearance of activated stellate cells for hepatic fibrosis regression: Molecular basis and translational potential

Kong, D., Zhang, F., Zhang, Z., Lu, Y., & Zheng, S. (2012) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2012.10.002 · Cited by 47 · see citing works

Hepatic Stellate Cells as a Target for the Treatment of Liver Fibrosis

Bataller, R. A., & Brenner, D. A. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-17558 · Cited by 493 · see citing works

The progression for the therapy of liver fibrosis targeting to hepatic stellate cells

Zhang, X. (2003) · Zhongguo yaolixue tongbao

Hepatic stellate cells: a target for the treatment of liver fibrosis

Wu, J., & Zern, M. Α. (2000) · Journal of Gastroenterology · doi:10.1007/s005350070045 · Cited by 275 · see citing works

Modulating hepatic stellate cell senescence: A promising therapeutic strategy for liver fibrosis

Sharmila, M., Harini, K. S., & Ezhilarasan, D. (2026) · Hepatobiliary & pancreatic diseases international · doi:10.1016/j.hbpd.2026.04.006