APOE polymorphism and its effect on plasma C-reactive protein levels in a large general population sample

A simple salting out procedure for extracting DNA from human nucleated cells

Miller, S. A., Dykes, D. D., & Polesky, H. F. (1988) · Nucleic Acids Research · doi:10.1093/nar/16.3.1215 · Cited by 20,341 · see citing works

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

Mahley, R. W. (1988) · Science · doi:10.1126/science.3283935 · Cited by 4,028 · see citing works

Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.

Hixson, J., & Vernier, D. (1990) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43176-1 · Cited by 2,933 · see citing works

Apolipoprotein E polymorphism and atherosclerosis.

Davignon, J., Gregg, R. E., & Sing, C. F. (1988) · Arteriosclerosis: An Official Journal of the American Heart Association, Inc. · doi:10.1161/01.atv.8.1.1 · Cited by 1,981 · see citing works

Genetically elevated C-reactive protein and ischemic vascular disease

Zacho, J., Tybjærg-Hansen, A., Jensen, J. S., Grande, P., Sillesen, H., & Nordestgaard, B. G. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0707402 · Cited by 839 · see citing works

C-Reactive Protein as a Cardiovascular Risk Factor

Lagrand, W. K., Visser, C. A., Hermens, W. T., Niessen, H. W. M., Verheugt, F. W. A., Wolbink, G., & Hack, C. E. (1999) · Circulation · doi:10.1161/01.cir.100.1.96 · Cited by 833 · see citing works

What Does Minor Elevation of C-Reactive Protein Signify?

Kushner, I., Rzewnicki, D., & Samols, D. R. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.06.057 · Cited by 372 · see citing works

C‐reactive protein and coronary heart disease: a critical review

Casas, J. P., Shah, T., Hingorani, A. D., Danesh, J., & Pepys, M. B. (2008) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2008.02015.x · Cited by 365 · see citing works

Determinants of cardiovascular disease and other non-communicable diseases in Central and Eastern Europe: Rationale and design of the HAPIEE study

Peasey, A., Bobák, M., Kubínová, R., Malyutina, S. K., Pająk, A., Tamošiūnas, A., Pikhart, H., Nicholson, A., & Marmot, M. G. (2006) · BMC Public Health · doi:10.1186/1471-2458-6-255 · Cited by 357 · see citing works

Loci Related to Metabolic-Syndrome Pathways Including LEPR,HNF1A, IL6R, and GCKR Associate with Plasma C-Reactive Protein: The Women's Genome Health Study

Ridker, P. M., Paré, G., Parker, A. N., Zee, R. Y. L., Danik, J. S., Buring, J. E., Kwiatkowski, D. J., Cook, N. R., Miletich, J. P., & Chasman, D. I. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.03.015 · Cited by 342 · see citing works

Impact of apoE genotype on oxidative stress, inflammation and disease risk

Jofre‐Monseny, L., Minihane, A. M., & Rimbach, G. H. (2008) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200700322 · Cited by 319 · see citing works

Apolipoprotein E polymorphism in a Danish population compared to findings in 45 other study populations around the world

Gerdes, L. U., Klausen, I. C., Sihm, I., Færgeman, O., & Vogler, G. P. (1992) · Genetic Epidemiology · doi:10.1002/gepi.1370090302 · Cited by 316 · see citing works

Inflammatory biomarkers and risks of myocardial infarction, stroke, diabetes, and total mortality: Implications for longevity

Ridker, P. M. (2007) · Nutrition Reviews · doi:10.1301/nr.2007.dec.s253-s259 · Cited by 264 · see citing works

Association of Common <i>CRP</i> Gene Variants with CRP Levels and Cardiovascular Events

Miller, D. T., Zee, R. Y. L., Suk Danik, J., Kozlowski, P., Chasman, D. I., Lazarus, R., Cook, N. R., Ridker, P. M., & Kwiatkowski, D. J. (2005) · Annals of Human Genetics · doi:10.1111/j.1529-8817.2005.00210.x · Cited by 220 · see citing works

ApoE Plasma Levels and Risk of Cardiovascular Mortality in Old Age

Mooijaart, S. P., Berbée, J. F. P., van Heemst, D., Havekes, L. M., de Craen, A. J. M., Slagboom, P. E., Rensen, P. C. N., & Westendorp, R. G. J. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030176 · Cited by 129 · see citing works

Inflammatory Biomarkers and Risks of Myocardial Infarction, Stroke, Diabetes, and Total Mortality: Implications for Longevity

Ridker, P. M. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00372.x · Cited by 128 · see citing works

The apolipoprotein E polymorphism is associated with circulating C-reactive protein (the Ludwigshafen risk and cardiovascular health study)

März, W., Scharnagl, H., Hoffmann, M. M., Boehm, B. O., & Winkelmann, B. R. (2004) · European Heart Journal · doi:10.1016/j.ehj.2004.08.024 · Cited by 87 · see citing works

Review: Biology and relevance of C-reactive protein in cardiovascular and renal disease.

Westhuyzen, J., & Healy, H. G. (2000) · PubMed · Cited by 79 · see citing works

New and confirmatory evidence of an association between APOE genotype and baseline C-reactive protein in dyslipidemic individuals

Judson, R., Brain, C. W., Dain, B., Windemuth, A., Ruaño, G., & Reed, C. R. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.07.012 · Cited by 65 · see citing works

Qualitative and quantitative effects of APOE genetic variation on plasma C-reactive protein, LDL-cholesterol, and apoE protein

Chasman, D. I., Kozłowski, P., Zee, R. Y. L., Kwiatkowski, D. J., & Ridker, P. M. (2006) · Genes and Immunity · doi:10.1038/sj.gene.6364289 · Cited by 64 · see citing works

Inflammation and atherosclerosis

Shishehbor, M. H., & Bhatt, D. L. (2004) · Current Atherosclerosis Reports · doi:10.1007/s11883-004-0102-x · Cited by 63 · see citing works

APOE polymorphism is associated with risk of severe sepsis in surgical patients*

Moretti, E. W., Morris, R. W., Podgoreanu, M. V., Schwinn, D. A., Newman, M. F., Bennett, E. R., Moulin, V. G., Uzo, U., & Laskowitz, D. T. (2005) · Critical Care Medicine · doi:10.1097/01.ccm.0000186368.96146.fb · Cited by 62 · see citing works

C-reactive protein and rate of dementia in carriers and non carriers of Apolipoprotein APOE4 genotype

Haan, M. N., Aiello, A. E., West, N. A., & Jagust, W. J. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.04.020 · Cited by 62 · see citing works

Heritability of C‐Reactive Protein and Association with Apolipoprotein E Genotypes in Japanese Americans

Austin, M. A., Zhang, C., Humphries, S. E., Chandler, W. L., Talmud, P. J., Edwards, K. L., Leonetti, D. L., McNeely, M. J., & Fujimoto, W. Y. (2004) · Annals of Human Genetics · doi:10.1046/j.1529-8817.2004.00078.x · Cited by 60 · see citing works

Apolipoprotein E genotype is related to plasma levels of C‐reactive protein and lipids and to longevity in nonagenarians

Rontu, R., Ojala, P., Hervonen, A., Goebeler, S., Karhunen, P. J., Nikkilä, M. T., Kunnas, T. A., Jylhä, M. K., Eklund, C., Hurme, M., et al. (2006) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2006.02455.x · Cited by 55 · see citing works

Apolipoprotein E genotype and statins affect CRP levels through independent and different mechanisms: AGES-Reykjavik Study

Eiríksdóttir, G., Aspelund, T., Bjarnadottir, K., Olafsdottir, E., Launer, L. J., Harris, T. B., & Gudnason, V. G. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.12.012 · Cited by 55 · see citing works

Apolipoprotein E Genotype and Circulating Interleukin-10 Levels in Patients With Stable and Unstable Coronary Artery Disease

Tziakas, D. N., Chalikias, G. K., Antonoglou, C., Veletza, S. V., Tentes, I. K., Kortsaris, A. X., Hatseras, D., & Kaski, J. C. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.08.032 · Cited by 50 · see citing works

High Levels of Serum C‐Reactive Protein Are Associated with Greater Risk of All‐Cause Mortality, but Not Dementia, in the Oldest‐Old: Results from The 90+ Study

Kravitz, B. A., Corrada, M. M., & Kawas, C. H. (2009) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02169.x · Cited by 45 · see citing works

Apolipoprotein E-Mediated Immune Regulation in Sepsis

Kattan, O. M., Kasravi, F. B., Elford, E. L., Schell, M. T., & Harris, H. W. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.2.1399 · Cited by 44 · see citing works

Apolipoprotein E Genotype in Dyslipidemic Patients and Response of Blood Lipids and Inflammatory Markers to Alpha-Linolenic Acid

Paschos, G. K., Yiannakouris, N., Rallidis, L. S., Davies, I. G., Griffin, B. A., Panagiotakos, D. B., Skopouli, F. N., Votteas, V., & Zampelas, A. (2005) · Angiology · doi:10.1177/000331970505600107 · Cited by 44 · see citing works

Genetic determinants of C-reactive protein

Danik, J. S., & Ridker, P. M. (2007) · Current Atherosclerosis Reports · doi:10.1007/s11883-007-0019-2 · Cited by 41 · see citing works

Apolipoprotein E Gene Polymorphism in the Mongolian Population

Svobodová, H., Kučera, F., Štulc, T., Vrablı́k, M., Amartuvshin, B., Altannavch, T., & Češka, R. (2007) · Folia Biologica · doi:10.14712/fb2007053040138 · Cited by 40 · see citing works

Apolipoprotein E polymorphism and C-reactive protein in dyslipidemic middle-aged men

Mänttäri, M., Manninen, V., Palosuo, T., & Ehnholm, C. (2001) · Atherosclerosis · doi:10.1016/s0021-9150(01)00480-4 · Cited by 38 · see citing works

Heritability and Expression of C‐Reactive Protein in Type 2 Diabetes in the Diabetes Heart Study

Lange, L. A., Burdon, K. P., Langefeld, C. D., Liu, Y., Beck, S. R., Rich, S. S., Freedman, B. I., Brosnihan, K. B., Herrington, D. M., Wagenknecht, L. E., et al. (2006) · Annals of Human Genetics · doi:10.1111/j.1469-1809.2006.00280.x · Cited by 35 · see citing works

Negative and independent influence of apolipoprotein E on C-reactive protein (CRP) concentration in obese adults. Potential anti-inflammatory role of apoE in vivo

Bach‐Ngohou, K., Nazih, H., Nazih‐Sanderson, F., Zaïr, Y., Carrer, D. L., Krempf, M., & Bard, J. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801833 · Cited by 29 · see citing works

Apolipoprotein E e4 allele affects risk of hyperhomocysteinemia in the elderly

Ravaglia, G., Forti, P., Maioli, F., Chiappelli, M., Montesi, F., Bianchin, M., Licastro, F., & Patterson, C. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.6.1473 · Cited by 27 · see citing works

Apolipoprotein E Mutants, Hyperlipidemia and Arteriosclerosis

Utermann, G. (1985) · Drugs Affecting Lipid Metabolism VIII · doi:10.1007/978-1-4613-2459-1_14 · Cited by 24 · see citing works

ApoE Polymorphism Is Associated With C‐Reactive Protein in Low‐HDL Family Members and in Normolipidemic Subjects

Kahri, J., Soro‐Paavonen, A., Ehnholm, C., & Taskinen, M. (2006) · Mediators of Inflammation · doi:10.1155/mi/2006/12587 · Cited by 20 · see citing works

Variable Expression of Hypercholesterolemia in Apolipoprotein E2* (Arg136®Cys) Heterozygotes

Hubacek, J. A., Piťha, J., Stávek, P., Schmitz, G., & Poledne, R. (2000) · Physiological Research · doi:10.33549/physiolres.930000.49.307 · Cited by 19 · see citing works

Association of high sensitive C-reactive protein with apolipoprotein E polymorphism in children and young adults: The Cardiovascular Risk in Young Finns Study

Grönroos, P. E., Raitakari, O. T., Kähönen, M. A. P., Hutri‐Kähönen, N., Marniemi, J., Viikari, J. S. A., & Lehtimäki, T. J. (2007) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2008.033 · Cited by 17 · see citing works

Heritability of serum hs-CRP concentration and 5-year changes in the Stanislas family study: association with apolipoprotein E alleles

Berrahmoune, H., Herbeth, B., Siest, G., & Visvikis‐Siest, S. (2007) · Genes and Immunity · doi:10.1038/sj.gene.6364395 · Cited by 15 · see citing works

Inflammatory Marker Expression and Its Implication in Korean Ischemic Stroke Patients

Park, S. Y., Kim, M. H., Kang, S. Y., Suh, J. T., & Lee, W. I. (2007) · Annals of Laboratory Medicine · doi:10.3343/kjlm.2007.27.3.197 · Cited by 15 · see citing works

Apolipoprotein E genotype and sex influence C-reactive protein levels regardless of exercise training status

Angelopoulos, T. J., Miles, M. P., Lowndes, J., Sivo, S. A., Seip, R. L., Pescatello, L. S., Zoeller, R. F., Visich, P. S., Gordon, P. M., Moyna, N. M., et al. (2008) · Metabolism · doi:10.1016/j.metabol.2008.04.013 · Cited by 6 · see citing works

Apolipoprotein E Arg136→Cys mutation and hyperlipidemia in a large central European population sample

Hubacek, J. A., Peasey, A., Pikhart, H., Adámková, V., Stávek, P., Marmot, M. G., Bobák, M., & Kubínová, R. (2007) · Clinica Chimica Acta · doi:10.1016/j.cca.2007.10.009 · Cited by 5 · see citing works

Apolipoprotein CI, and not apolipoprotein E, polymorphism affects plasma levels of C-reactive protein?

Hubacek, J. A., Stávek, P., Adámková, V., Lánská, V., & Škodová, Z. (2005) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2005.04.006 · Cited by 3 · see citing works

Recent Advancements in Pathogenesis, Diagnostics and Treatment of Alzheimer’s Disease

Khan, S., Barve, K. H., & Kumar, M. S. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200528142429 · Cited by 820 · see citing works

<i><i>Bifidobacterium infantis</i></i>35624 modulates host inflammatory processes beyond the gut

Groeger, D., O’Mahony, L., Murphy, E. F., Bourke, J. F., Dinan, T. G., Kiely, B., Shanahan, F., & Quigley, E. M. M. (2013) · Gut Microbes · doi:10.4161/gmic.25487 · Cited by 448 · see citing works

Genome‐wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

Deelen, J., Beekman, M., Uh, H., Helmer, Q., Kuningas, M., Christiansen, L., Kremer, D., van der Breggen, R., Suchiman, H. E. D., Lakenberg, N., et al. (2011) · Aging Cell · doi:10.1111/j.1474-9726.2011.00705.x · Cited by 280 · see citing works

Effect of quercetin on traits of the metabolic syndrome, endothelial function and inflammation in men with different APOE isoforms

Pfeuffer, M., Auinger, A., Bley, U., Kraus-Stojanowic, I., Laue, C., Winkler, P., Rüfer, C. E., Frank, J., Boesch‐Saadatmandi, C., Rimbach, G. H., et al. (2011) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2011.08.010 · Cited by 182 · see citing works

Genetic associations for two biological age measures point to distinct aging phenotypes

Kuo, C., Pilling, L. C., Liu, Z., Atkins, J. L., & Levine, M. E. (2021) · Aging Cell · doi:10.1111/acel.13376 · Cited by 172 · see citing works

Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer’s disease

Brosseron, F., Traschütz, A., Widmann, C. N., Kummer, M. P., Tacik, P., Santarelli, F., Jessen, F., & Heneka, M. T. (2018) · Alzheimer's Research &amp; Therapy · doi:10.1186/s13195-018-0353-3 · Cited by 113 · see citing works

ApoE genotype: from geographic distribution to function and responsiveness to dietary factors

Egert, S., Rimbach, G. H., & Huebbe, P. (2012) · Proceedings of The Nutrition Society · doi:10.1017/s0029665112000249 · Cited by 95 · see citing works

Systemic inflammation as a predictor of brain aging: Contributions of physical activity, metabolic risk, and genetic risk

Corlier, F. W., Hafzalla, G. W., Faskowitz, J., Kuller, L. H., Becker, J. T., López, O. L., Thompson, P. M., & Braskie, M. N. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2017.12.027 · Cited by 94 · see citing works

Multivariate Protein Signatures of Pre-Clinical Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Plasma Proteome Dataset

Johnstone, D. M., Milward, E. A., Berretta, R. E., Moscato, P., & Initiative, A. D. N. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034341 · Cited by 82 · see citing works

The Role of Sleep and Sleep Disorders in the Development, Diagnosis, and Management of Neurocognitive Disorders

Miller, M. A. (2015) · Frontiers in Neurology · doi:10.3389/fneur.2015.00224 · Cited by 73 · see citing works

Elevated salivary C-reactive protein predicted by low cardio-respiratory fitness and being overweight in African children : cardiovascular topic

Naidoo, T., Konkol, K. F., Biccard, B. M., DuBose, K. D., & McKune, A. J. (2012) · Cardiovascular journal of South Africa/Cardiovascular journal of Southern Africa · doi:10.5830/cvja-2012-058 · Cited by 53 · see citing works

C-reactive protein (CRP) gene polymorphisms, CRP levels and risk of incident essential hypertension: findings from an observational cohort of Han Chinese

Kong, H., Qian, Y., Tang, X., Zhang, J., Gao, P., Zhang, Y., & Zhu, D. (2012) · Hypertension Research · doi:10.1038/hr.2012.89 · Cited by 41 · see citing works

C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia

Fernandes, A. S., Tábuas‐Pereira, M., Duro, D., Lima, M., Gens, H., Santiago, B., Durães, J., Almeida, M. R., Leitão, M. J., Baldeiras, I., et al. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.111004 · Cited by 36 · see citing works

Association of salivary C-reactive protein with the obesity measures and markers in children

Selvaraju, V., Babu, J. R., & Geetha, T. (2019) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s211624 · Cited by 35 · see citing works

Inflammation in Alzheimer’s Disease: Do Sex and APOE Matter?

Duarte‐Guterman, P., Initiative, O. B. O. T. A. D. N., Albert, A., Inkster, A. M., Barha, C. K., & Galea, L. A. M. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200982 · Cited by 30 · see citing works

C-reactive protein and familial risk for dementia

Silverman, J. M., Schmeidler, J., Beeri, M. S., Rosendorff, C., Sano, M. C., Grossman, H. T., Carrión‐Baralt, J. R., Bespalova, I. N., West, R. K., & Haroutunian, V. H. (2012) · Neurology · doi:10.1212/wnl.0b013e3182698c89 · Cited by 30 · see citing works

Associations of apolipoprotein E and low‐density lipoprotein receptor‐related protein 5 polymorphisms with dyslipidemia and generalized aggressive periodontitis in a C hinese population

Gao, H., Tian, Y., Meng, H., Hou, J., Xu, L., Zhang, L., Shi, D., Lu, R., Feng, X., Wang, X., et al. (2014) · Journal of Periodontal Research · doi:10.1111/jre.12237 · Cited by 28 · see citing works

Associations between APOE Genotypes and Disease Susceptibility, Joint Damage and Lipid Levels in Patients with Rheumatoid Arthritis

Mæhlen, M. T., Provan, S. A., de Rooy, D. P. C., Mil, A. H. M. V. D. H., Krabben, A., Saxne, T., Lindqvist, E., Semb, A. G., Uhlig, T., van der Heijde, D. M. F. M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060970 · Cited by 27 · see citing works

Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers

Martiskainen, H., Takalo, M., Solomon, A., Stančáková, A., Marttinen, M., Natunen, T., Haapasalo, A., Herukka, S., Kuusisto, J., Soininen, H. S., et al. (2018) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.639 · Cited by 25 · see citing works

Salivary Amylase Gene Copy Number Is Associated with the Obesity and Inflammatory Markers in Children

Selvaraju, V., Venkatapoorna, C. M. K., Babu, J. R., & Geetha, T. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s251359 · Cited by 24 · see citing works

APOE – a genetic marker of comorbidity in subjects with morbid obesity

Farup, P. G., Rootwelt, H., & Hestad, K. A. (2020) · BMC Medical Genetics · doi:10.1186/s12881-020-01082-2 · Cited by 24 · see citing works

Porphyromonas gingivalis Conditioned Medium Induces Amyloidogenic Processing of the Amyloid-β Protein Precursor upon in vitro Infection of SH-SY5Y Cells

Kanagasingam, S., von Ruhland, C. J., Welbury, R. R., Chukkapalli, S. S., & Singhrao, S. K. (2022) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-220029 · Cited by 24 · see citing works

Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study

Low, A., Su, L., Stefaniak, J. D., Mak, E., Dounavi, M., Terrera, G. M., Ritchie, K. A., Ritchie, C. W., Markus, H. S., & O'Brien, J. T. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.10.029 · Cited by 23 · see citing works

Apolipoprotein ɛ4-Associated Protection Against Pediatric Enteric Infections Is a Survival Advantage in Pre-Industrial Populations

Smith, C. J., & Ashford, J. W. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-221218 · Cited by 22 · see citing works

Longitudinal association of Apolipoprotein E polymorphism with lipid profile, type 2 diabetes and metabolic syndrome: Results from a 15 year follow-up study

Pitchika, A., Markus, M. R. P., Schipf, S., Teumer, A., der Auwera, S. V., Nauck, M. A., Dörr, M., Felix, S. B., Grabe, H. J., Völzke, H., et al. (2022) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2022.109778 · Cited by 21 · see citing works

Identification of circulating proteins associated with general cognitive function among middle-aged and older adults

Tin, A., Fohner, A. E., Yang, Q., Brody, J. A., Davies, G., Yao, J., Liu, D., Caro, I., Lindbohm, J. V., Duggan, M. R., et al. (2023) · Communications Biology · doi:10.1038/s42003-023-05454-1 · Cited by 20 · see citing works

Few serum proteins mediate APOE’s association with dementia

Royall, D. R., Al-Rubaye, S., Bishnoi, R. J., & Palmer, R. F. (2017) · PLoS ONE · doi:10.1371/journal.pone.0172268 · Cited by 20 · see citing works

Interactive effects of C-reactive protein levels on the association between APOE variants and triglyceride levels in a Taiwanese population

Wu, S., Hsu, L., Teng, M., Lin, J.-F., Chou, H., Lee, M., Yi-ming, W., Su, C.-W., & Ko, Y. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0262-z · Cited by 20 · see citing works

Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study

Lutz, M. W., Casanova, R., Saldana, S. J., Kuchibhatla, M. N., Plassman, B. L., & Hayden, K. M. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.10.028 · Cited by 19 · see citing works

APOE Genotypes Modulate Inflammation Independently of Their Effect on Lipid Metabolism

Marin, M. C., Cenarro, A., Marco-Benedí, V., Bea, A. M., Mateo‐Gállego, R., Moreno‐Franco, B., Ordovás, J. M., Laclaustra, M., Civeira, F., & Lamíquiz-Moneo, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112947 · Cited by 19 · see citing works

Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations

Hong, E. P., Kim, D. H., Suh, J., & Park, J. W. (2014) · Hypertension Research · doi:10.1038/hr.2014.56 · Cited by 19 · see citing works

Apolipoprotein E genetic variants interact with Mediterranean diet to modulate postprandial hypertriglyceridemia in coronary heart disease patients: CORDIOPREV study

Gómez-Delgado, F., Alcala-Diaz, J. F., Leon‐Acuña, A., López-Moreno, J., Delgado‐Lista, J., Gomez‐Marin, B., Roncero‐Ramos, I., Yubero‐Serrano, E. M., Rangel-Zúñiga, O. A., Vals‐Delgado, C., et al. (2019) · European Journal of Clinical Investigation · doi:10.1111/eci.13146 · Cited by 18 · see citing works

Chronically raised C-reactive protein is inversely associated with cortical β-amyloid in older adults with subjective memory complaints

Hooper, C., Barreto, P. D. S., Cantet, C., Cesari, M., Payoux, P., Salabert, A., & Vellas, B. J. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.04.014 · Cited by 16 · see citing works

Apolipoprotein E (APOE) ε4 moderates the relationship between c-reactive protein, cognitive functioning, and white matter integrity

Wooten, T., Brown, E. M., Sullivan, D. R., Logue, M. W., Fortier, C. B., Fonda, J. R., Degutis, J. M., Salat, D. H., McGlinchey, R. E., Milberg, W., et al. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.02.016 · Cited by 15 · see citing works

Insights into the pleiotropic relationships between chronic back pain and inflammation-related musculoskeletal conditions: rheumatoid arthritis and osteoporotic abnormalities

Kasher, M., Williams, F. M. K., Freidin, M. B., Cherny, S. S., Malkin, I., CHARGE Inflammation Working Group, & Livshits, G. (2022) · Pain · doi:10.1097/j.pain.0000000000002728 · Cited by 15 · see citing works

APOE4 Copy Number-Dependent Proteomic Changes in the Cerebrospinal Fluid1

Berger, M., Cooter, M., Roesler, A. S., Chung, S., Park, J., Modliszeski, J. L., VanDusen, K. W., Thompson, J. W., Moseley, M. A., Devinney, M. J., et al. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200747 · Cited by 15 · see citing works

Periodontitis as a Risk Factor for Alzheimer’s Disease: The Experimental Journey So Far, with Hope of Therapy

Harding, A., Kanagasingam, S., Welbury, R. R., & Singhrao, S. K. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-96881-6_13 · Cited by 14 · see citing works

Impact of hs-CRP concentration on brain structure alterations and cognitive trajectory in Alzheimer’s disease

Zhang, Y., Tatewaki, Y., Nakase, T., Liu, Y., Tomita, N., Thyreau, B., Zheng, H., Muranaka, M., Takano, Y., Nagasaka, T., et al. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1227325 · Cited by 14 · see citing works

C-reactive protein levels and risk of disabling dementia with and without stroke in Japanese: The Circulatory Risk in Communities Study (CIRCS)

Chei, C., Yamagishi, K., Ikeda, A., Noda, H., Maruyama, M., Cui, R., Imano, H., Kiyama, M., Kitamura, A., Asada, T., et al. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.07.036 · Cited by 13 · see citing works

Family Member Deaths in Childhood Predict Systemic Inflammation in Late Life

Norton, M. C., Hatch, D., Munger, R. G., & Smith, K. R. (2017) · Biodemography and Social Biology · doi:10.1080/19485565.2017.1281099 · Cited by 13 · see citing works

APOEPolymorphism Is Associated with C-reactive Protein Levels but Not with White Blood Cell Count: Dong-gu Study and Namwon Study

Yun, Y.-W., Kweon, S., Choi, J.-S., Rhee, J.-A., Lee, Y. H., Nam, H., Jeong, S., Park, K.-S., Ryu, S. Y., Choi, S.-W., et al. (2015) · Journal of Korean Medical Science · doi:10.3346/jkms.2015.30.7.860 · Cited by 12 · see citing works

Statin use moderates APOE's and CRP's associations with dementia and is associated with lesser dementia severity in ε4 carriers

Royall, D. R., Palmer, R. F., & Initiative, A. D. N. (2023) · Alzheimer s & Dementia · doi:10.1002/alz.13543 · Cited by 11 · see citing works

Quantile-dependent expressivity of serum C-reactive protein concentrations in family sets

Williams, P. T. (2021) · PeerJ · doi:10.7717/peerj.10914 · Cited by 10 · see citing works

The mediating role of systemic inflammation and moderating role of racialization in disparities in incident dementia

Tejera, C. H., Ware, E. B., Hicken, M. T., Kobayashi, L. C., Wang, H., Adkins‐Jackson, P. A., Blostein, F., Zawistowski, M., Mukherjee, B., & Bakulski, K. M. (2024) · Communications Medicine · doi:10.1038/s43856-024-00569-w · Cited by 10 · see citing works

Analysis of the Potential Role of Apolipoprotein E Polymorphism in Genetic Predisposition to Spontaneous Abortion

Rynekrová, J., Kašparová, D., Adámková, V., Fait, T., & Hubacek, J. A. (2011) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2011.01071.x · Cited by 10 · see citing works

Association of Apolipoprotein E Polymorphism with Adipokines and Cardiovascular Disease Risk in Rheumatoid Arthritis Patients

Chen, Y., Chen, P., Chang, C., Lin, C., Chen, H., Lan, J., Chang, S., & Chen, D. (2020) · Life · doi:10.3390/life10120330 · Cited by 9 · see citing works

Heterogeneous effects of genetic risk for Alzheimer’s disease on the phenome

Wu, H. M., Goate, A., & O’Reilly, P. F. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01518-0 · Cited by 8 · see citing works

Apolipoprotein E variants correlate with the clinical presentation of paediatric inflammatory bowel disease: A cross-sectional study

Glapa-Nowak, A., Szczepanik, M., Iwańczak, B. M., Kwiecień, J., Szaflarska‐Popławska, A., Grzybowska‐Chlebowczyk, U., Osiecki, M., Dziekiewicz, M., Stawarski, A., Kierkuś, J., et al. (2021) · World Journal of Gastroenterology · doi:10.3748/wjg.v27.i14.1483 · Cited by 7 · see citing works

On a Western diet, APOE ɛ4 is associated with low innate immune sensing, but not APOE ɛ3

Dose, J., Schloesser, A., Torres, G. G., Venkatesh, G., Häsler, R., Flachsbart, F., Lieb, W., Nebel, A., Rimbach, G. H., & Huebbe, P. (2018) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.05.033 · Cited by 6 · see citing works

Genetic pleiotropy underpinning adiposity and inflammation in self-identified Hispanic/Latino populations

Anwar, M. Y., Baldassari, A., Polikowsky, H. G., Sitlani, C. M., Highland, H. M., Chami, N., Chen, H., Graff, M., Howard, A. G., Jung, S. Y., et al. (2022) · BMC Medical Genomics · doi:10.1186/s12920-022-01352-3 · Cited by 5 · see citing works

Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population

Алексеевна, М. О., Kholmatova, K., Постоева, А. В., Николаевна, К. Г., Malyutina, S. K., & Kudryavtsev, A. V. (2023) · Biomolecules · doi:10.3390/biom13050835 · Cited by 5 · see citing works

Does Apolipoprotein E genotype affect cardiovascular risk in subjects with acromegaly?

Çetintaş, V. B., Zengi, A., Vardarli, A. T., Karadeniz, M., Ergonen, F., Küçükaslan, A. Ş., Tamsel, S., Kosova, B., Şahin, S. B., Saygılı, F., et al. (2011) · Endocrine · doi:10.1007/s12020-011-9585-8 · Cited by 4 · see citing works

Inflammation in Alzheimer’s disease: do sex and APOE matter?Preprint

Duarte‐Guterman, P., Albert, A., Inkster, A. M., Barha, C. K., Galea, L. A. M., & Initiative, O. B. O. T. A. D. N. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/741777 · Cited by 4 · see citing works

CASE REPORT OF A PATIENT WITH RARE P.ARG136CYS (APOE2*) MUTATION IN APOLIPOPROTEIN E GENE

Lisyova (2014) · OnLine Journal of Biological Sciences · doi:10.3844/ojbsci.2014.36.43 · Cited by 2 · see citing works

Lipoprotein glomerulopathy with markedly increased arterial stiffness successfully treated with a combination of fenofibrate and losartan: a case report

Kato, J., Okonogi, H., Kanzaki, G., Katsumata, H., Nakada, Y., Sagasaki, M., Komine, K., Ito, K., Saito, T., Matsunaga, A., et al. (2024) · BMC Nephrology · doi:10.1186/s12882-024-03612-z · Cited by 1 · see citing works

The association between APO-E genotype and inflammation and the risk of premature CHD in smokers versus non-smokers

Nath, D., Shivasekar, M., & Mohanakrishnan, V. V. (2024) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2024.155144 · Cited by 1 · see citing works

Stools from a human APOEe2 donor reduces amyloid and tau pathology and increases neuroinflammation in a 3xTg AD mouse model

Marizzoni, M., Tournier, B. B., Chevalier, C., Saleri, S., Lathuilière, A., Ceyzériat, K., Paquis, A., Park, R., Troesch, E., Cattaneo, A., et al. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1539067 · Cited by 1 · see citing works

Interactions of genetic and non-genetic factors on plasma hs-CRP concentration in a Korean community-based cohort study

Hong, E. P., Kim, D.-H., & Park, J. W. (2014) · Genes & Genomics · doi:10.1007/s13258-014-0240-7 · Cited by 1 · see citing works

The APOE ε2 allele is associated with increased plasma apolipoprotein E levels in patients with coronary artery disease

Pleva, L., Kušnierová, P., Plevová, P., Hilscherová, Š., Karpíšek, M., Zapletalová, J., Faldynová, L., Kovářová, P., & Kukla, P. (2017) · Cor et Vasa · doi:10.1016/j.crvasa.2016.11.011 · Cited by 1 · see citing works

A blood-based signature of cerebrospinal fluid A β 1–42 statusPreprint

Goudey, B., Fung, B. J., Schieber, C., Initiative, A. D. N., & Faux, N. G. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/190207 · Cited by 1 · see citing works

The Role of Diet, Erythrocyte Membrane Fatty Acid Composition, and Alzheimer's-related Genes in Systemic Inflammation in the Cache County Memory Study

Jalloun, R. A. (2021) · Digital Commons - USU (Utah State University) · doi:10.26076/4558-0376

Exploring the link between periodontal disese and general health issues

Singhrao, S. K., & Crean, S. J. (2010) · Faculty Dental Journal · doi:10.1308/204268510x12804170471061

Analysis of Methylation and Expression Profiles of CPT1-A and APOE Genes in Patients with NAFLD

Baranzehi, T. (2013) · Journal of Liver Disease & Transplantation · doi:10.4172/2325-9612.1000116

Peer Review #1 of "Quantile-dependent expressivity of serum C-reactive protein concentrations in family sets (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.10914v0.1/reviews/1

Peer Review #1 of "Quantile-dependent expressivity of serum C-reactive protein concentrations in family sets (v0.2)"

(2021) · PeerJ · doi:10.7287/peerj.10914v0.2/reviews/1

FRACTIONAL URIC ACID EXCRETION AND C-REACTIVE PROTEIN CONCENTRATION IN TYPE 2 DIABETES MELLITUS: THE INFLUENCE OF GLYCEMIC CONTROL

Ekaidem, E., I.S., I. S., ab, A., Udoh, U. H., I.F.c, I. F. C., Usoroh, U., & A.J.a, A. J. A. (2020) · International Journal of Research Publications · doi:10.47119/ijrp100571720201341

Peer Review #2 of "Quantile-dependent expressivity of serum C-reactive protein concentrations in family sets (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.10914v0.1/reviews/2

Peer Review #3 of "Quantile-dependent expressivity of serum C-reactive protein concentrations in family sets (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.10914v0.1/reviews/3

The inverse association between the apolipoprotein E ε4 allele and C‐reactive protein levels is stronger in persons with obesity and diabetes

Giil, L. M., Hanseth, S., Bojović, O., Nordrehaug, J. E., Ueland, P. M., Meyer, K., & Tell, G. S. (2023) · Scandinavian Journal of Immunology · doi:10.1111/sji.13323

Additional file 5 of Genetic pleiotropy underpinning adiposity and inflammation in self-identified Hispanic/Latino populations

Anwar, M. Y., Baldassari, A., Polikowsky, H. G., Sitlani, C. M., Highland, H. M., Chami, N., Chen, H., Graff, M., Howard, A. G., Jung, S. Y., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21077664

Effects of the interaction between seaweed consumption and the polygenic risk score on inflammation in Korean adults

Hong, G., & Shin, D. (2024) · Journal of Nutrition and Health · doi:10.4163/jnh.2024.57.2.211

Bioinformatics insights into transcriptomic biomarkers for atopic dermatitis

Adikusuma, W., Mugiyanto, E., Irham, L. M., Firdayani, F., Listiana, S., Iresha, M. R., Masyita, A., Mazaya, M., & Alfian, R. (2025) · Journal of Research in Pharmacy · doi:10.12991/jrespharm.1693724

Immunomodulatory Effects of apoE on Colitis

Tan, D., Xu, B., & Zheng, T. (2025) · Springer eBooks · doi:10.1007/978-3-031-52641-1_64-1

Additional file 1 of Genetic pleiotropy underpinning adiposity and inflammation in self-identified Hispanic/Latino populations

Anwar, M. Y., Baldassari, A., Polikowsky, H. G., Sitlani, C. M., Highland, H. M., Chami, N., Chen, H.-H., Graff, M., Howard, A. G., Jung, S. Y., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21077652

Additional file 3 of Genetic pleiotropy underpinning adiposity and inflammation in self-identified Hispanic/Latino populations

Anwar, M. Y., Baldassari, A., Polikowsky, H. G., Sitlani, C. M., Highland, H. M., Chami, N., Chen, H.-H., Graff, M., Howard, A. G., Jung, S. Y., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21077658

Additional file 2 of Genetic pleiotropy underpinning adiposity and inflammation in self-identified Hispanic/Latino populations

Anwar, M. Y., Baldassari, A., Polikowsky, H. G., Sitlani, C. M., Highland, H. M., Chami, N., Chen, H.-H., Graff, M., Howard, A. G., Jung, S. Y., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21077655

Additional file 6 of Genetic pleiotropy underpinning adiposity and inflammation in self-identified Hispanic/Latino populations

Anwar, M. Y., Baldassari, A., Polikowsky, H. G., Sitlani, C. M., Highland, H. M., Chami, N., Chen, H.-H., Graff, M., Howard, A. G., Jung, S. Y., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21077667

Additional file 4 of Genetic pleiotropy underpinning adiposity and inflammation in self-identified Hispanic/Latino populations

Anwar, M. Y., Baldassari, A., Polikowsky, H. G., Sitlani, C. M., Highland, H. M., Chami, N., Chen, H.-H., Graff, M., Howard, A. G., Jung, S. Y., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21077661

APOE, Cardiovascular Surgery, and Cognitive Outcomes

Smith, C. J., Smith, R. S., & Perfetti, T. A. (2025) · Springer eBooks · doi:10.1007/978-3-031-52641-1_81-1

Persistent Sex Differences in Cardiovascular Disease Risk Factors: A Longitudinal Cohort Study in Youth With Type 1 Diabetes

Schweiger, D. Š., Mlinarič, Z., Macedoni, M., Giani, E., Plesnik, E., Hovnik, T., Kotnik, P., Dovč, K., Bratina, N., Battelino, T., et al. (2026) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2026.108391

Association of C-reactive protein with brain micro- and macro-structure among older adult men

Bell, T. R., Pearce, R. C., Puckett, O. K., Hagler, D. J., Dale, A. M., Elman, J. A., Fennema‐Notestine, C., Franz, C. E., Lyons, M. J., Panizzon, M. S., et al. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.106798

APOE, Cardiovascular Surgery, and Cognitive Outcomes

Smith, C. J., SMITH, R. S., & Perfetti, T. A. (2026) · Springer eBooks · doi:10.1007/978-3-031-96089-5_81

New and confirmatory evidence of an association between APOE genotype and baseline C-reactive protein in dyslipidemic individuals

Judson, R., Brain, C. W., Dain, B., Windemuth, A., Ruaño, G., & Reed, C. R. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.07.012 · Cited by 65 · see citing works

Qualitative and quantitative effects of APOE genetic variation on plasma C-reactive protein, LDL-cholesterol, and apoE protein

Chasman, D. I., Kozłowski, P., Zee, R. Y. L., Kwiatkowski, D. J., & Ridker, P. M. (2006) · Genes and Immunity · doi:10.1038/sj.gene.6364289 · Cited by 64 · see citing works

Apolipoprotein E polymorphism has no cross sectional association with C‐reactive protein levels in women

Lowndes, J., Zoeller, R. F., Moyna, N. M., Gordon, P. M., Visich, P. S., Pescatello, L. S., Miles, M. P., Seip, R. L., Thompson, P. D., & Angelopoulos, T. J. (2007) · The FASEB Journal · doi:10.1096/fasebj.21.6.a868-b · Cited by 1 · see citing works

Association of high sensitive C-reactive protein with apolipoprotein E polymorphism in children and young adults: The Cardiovascular Risk in Young Finns Study

Grönroos, P. E., Raitakari, O. T., Kähönen, M. A. P., Hutri‐Kähönen, N., Marniemi, J., Viikari, J. S. A., & Lehtimäki, T. J. (2007) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2008.033 · Cited by 17 · see citing works

Relationship Between Serum C-reactive protein Levels and Apolipoprotein E Gene Polymorphism: A Meta-AnalysisPreprint

Wang, L., Xiao-yin, H., He, Y., Zhang, L., Wang, R., & Shi, S. (2021) · Research Square · doi:10.21203/rs.3.rs-164103/v1