Cited by 456Diet and metabolism studiesFatty Acid Research and HealthCoconut Research and Applications

The DOI matches its Crossref record; 86 of the 86 references it cites were found in a registry or an index.

Medium-chain triglycerides

Marten, Berit, Pfeuffer, Maria, Schrezenmeir, Jürgen·2006·International Dairy Journal

DOI 10.1016/j.idairyj.2006.06.015

Open this paper in CoChat — free account

Abstract

Medium-chain fatty acids (MCFAs) comprise saturated fatty acids with 6-10 carbons. Besides synthetic medium-chain triglyceride (MCT) oils there are natural sources, like coconut oil and dairy fat. Compared with long-chain fatty acids (LCFAs), the chemical and physical properties of MCFAs show substantial metabolic differences. MCFAs do not require binding to proteins such as fatty-acid binding protein, fatty acid transport protein, and/or fatty acid translocase (FAT, homolog to human platelet CD36). MCFAs are a preferred source of energy (β-oxidation). MCFAs are also incorporated into adipose tissue triglycerides, and may influence adipose tissue and other systemic functions more substantially than previously assumed. MCTs reduce fat mass, through down-regulation of adipogenic genes as well as peroxisome proliferator activated receptor-γ. Recent studies confirmed the potential of MCFAs to reduce body weight and particularly body fat. This effect was not transient. MCFAs reduce lipoprotein secretion and attenuate postprandial triglyceride response. It was, however, frequently observed that MCTs increase fasting cholesterol and triglyceride levels. But, given in moderate amounts, in diets with moderate fat supply, MCFAs may actually reduce fasting lipid levels more than oils rich in mono- or polyunsaturated fatty acids. The same is true for glucose levels. MCTs improved several features contributing to enhanced insulin sensitivity. Under certain in vitro conditions, MCTs exert…

Integrity signals

Registry

Crossref · 10.1016/j.idairyj.2006.06.015

Cites

86 of 86 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials
Mensink, R. P., Zock, P. L., Kester, A. D., & Katan, M. B. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.5.1146 · Cited by 2,811
Medium-chain triglycerides: an update
Bach, A., & Babayan, V. (1982) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/36.5.950 · Cited by 1,151
The Composition of Bovine Milk Lipids: January 1995 to December 2000
Jensen, R. G. (2002) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(02)74079-4 · Cited by 1,123
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
Aitman, T. J., Glazier, A. M., Wallace, C. A., Cooper, L. D., Norsworthy, P. J., Wahid, F. N., Al-Majali, K., Trembling, P. M., Mann, C. J., Shoulders, C. C., et al. (1999) · Nature Genetics · doi:10.1038/5013 · Cited by 733
Dietary fat, insulin sensitivity and the metabolic syndrome
Riccardi, G., Giacco, R., & Rivellese, A. A. (2004) · Clinical Nutrition · doi:10.1016/j.clnu.2004.02.006 · Cited by 634
Review of the toxicologic properties of medium-chain triglycerides
Traul, K. A., Driedger, A., Ingle, D. L., & Nakhasi, D. K. (2000) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(99)00106-4 · Cited by 429
Medium chain fatty acid metabolism and energy expenditure: obesity treatment implications.
Papamandjaris, A. A., Macdougall, D., & Jones, P. (1998) · Life Science · doi:10.1016/s0024-3205(97)01143-0 · Cited by 387
Medium chain triglycerides and structured lipids
Babayan, V. K. (1987) · Lipids · doi:10.1007/bf02537271 · Cited by 372
Physiological Effects of Medium-Chain Triglycerides: Potential Agents in the Prevention of Obesity
St‐Onge, M., & Jones, P. J. H. (2002) · Journal of Nutrition · doi:10.1093/jn/132.3.329 · Cited by 369
Postprandial lipoprotein metabolism and atherosclerosis.
Karpe, F. (1999) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1999.00548.x · Cited by 360

Show all 85 references

Sorted by citations

Items 401–456 of 456

Optimization of Hydrocolloid Levels in Medium-Chain Triglyceride-Enriched Soymilk by Response Surface Methodology
Villones, I. T. Y., & Dumelod, B. D. (2020) · International Electronic Conference on Foods (Foods) · doi:10.3390/foods_2020-07815 · Cited by 1
Polysaccharides of Biomedical Importance from Genetically Modified Microorganisms
Dass, R. S., Anand, K. R., Saha, D., Dhinakar, J. E., & Thorat, P. A. (2021) · Springer eBooks · doi:10.1007/978-3-030-35734-4_38-1 · Cited by 1
Bioactive Lipids
Vázquez, L., Corzo‐Martínez, M., Arranz‐Martínez, P., Barroso, E., Reglero, G., & Torres, C. F. (2017) · Reference series in phytochemistry · doi:10.1007/978-3-319-54528-8_58-1 · Cited by 1
Nutraceuticals–Functional Foods for Improving Health and Preventing Disease
Zhao, J. H. (2012) · Pharmaceutical biotechnology · doi:10.1002/9783527632909.ch23 · Cited by 1
Modulatin of immune function by medium chain triglycerides
Kortekaas, S. P. M. (2013) · Utrecht University Repository (Utrecht University) · Cited by 1
HPLC Determination of Medium-Chain Fatty Acids in Human Plasma and Their Relationship with Homocysteine Concentration
園部, 千., Nakamura, M., Wada, M., & Nakashima, K. (2008) · BUNSEKI KAGAKU · doi:10.2116/bunsekikagaku.57.631 · Cited by 1
Development of paediatric dosage forms of furosemide using the problem structuring method of morphological analysis
Baghdadi, H. (2016) · London Met Repository (London Metropolitan University) · Cited by 1
Optimization of lipase-catalyzed synthesis of flaxseed oil-based structured lipids in non-conventional media
Khodadadi, M. (2012) · eScholarship@McGill (McGill) · doi:10.82308/51642 · Cited by 1
Calorie‐Reduced Lipids and Health
Shahidi, F., & Nguyen, L. V. (2020) · Wiley eBooks · doi:10.1002/047167849x.bio111 · Cited by 1
Milk quality – a future approach from a researcher’s point of view
R, A., Borge, G. I. A., Harstad, O. M., Haug, A., & Wetlesen, A. (2007) · Journal of Animal and Feed Sciences · doi:10.22358/jafs/74198/2007 · Cited by 1
Digestibilidade in vitro de micropartículas lipídicas sólidas contendo óleo de babaçu e determinação de bioacessibilidade de quercetina encapsulada
Pereira, C. P. (2015) · doi:10.11606/d.74.2015.tde-15052015-161500
PROFIL MEDIUM CHAIN FATTY ACIDS (MCFA) DAN SIFAT KIMIA MINYAK KELAPA (VIRGIN COCONUT OIL/VCO, MINYAK SIMPLAH, PLIEK U, KLENTIK, DAN KOPRA) DIBANDINGKAN DENGAN MINYAK SAWIT (MEDIUM CHAIN FATTY ACIDS (MCFA) PROFILE AND CHEMICAL PROPERTIES OF COCONUT OILS (VIRGIN COCONUT OIL/VCO, SIMPLAH OIL, PLIEK U OIL, KLENTIK OIL, AND COPRA OIL) COMPARE TO PALM OIL)
Arpi, N. (2013)
Specialty Products
Badotti, F., Gomes, F. C. O., & Rosa, C. A. (2012) · CRC Press eBooks · doi:10.1201/b12055-42
Desenvolvimento e avaliação da segurança e eficácia de nanoemulsão com cafeína com ação na HDLG
Freire, T. B. (2017) · doi:10.11606/d.9.2017.tde-01062017-162648
Determination of the Mutagenicity of Four Vegetable Oils After Heat Treatment
Okyere, G. O. (2013)
Energiebedarf, Nährstoffe, Nahrungsbestandteile, Verdauung, Resorption und Stoffwechsel
Kasper, H. (2014) · Elsevier eBooks · doi:10.1016/b978-3-437-42013-9.00001-4
How Low Do You Need to Go? Exploring the Variability in the Effects of Keto‐induction and Individual Outcomes From Low‐carbohydrate Diets
Harvey, C. (2019) · Tuwhera (Auckland University of Technology)
Role of bioactive lipids in metabolism of obese patients and prospects for their use in the postoperative period
А.Б., Ф., Ospanov, O. B., & Fursov, R. (2021) · Сибирский научный медицинский журнал · doi:10.18699/ssmj20210302
Nanomedicine via Freeze‐drying and Ice Templating
Zhang, H. (2018) · Wiley eBooks · doi:10.1002/9783527807390.ch8
Effect of Octyl Salicylate With Respect To the Physical Appearance of Mono/Di Caprylic and Capric Fatty Acids Formulations
(2016) · Journal of Pharmaceutical Research · doi:10.33140/jpr/01/01/00003
SOLVENT FREE ENZYMATIC TRANSESTERIFICATION FOR SYNTHESIS OF 1,3-DIFERULOYL-2-CAPRYL GLYCEROL FERULOYLATED DESIGNER LIPID INTENSIFIED USING SONICATION
Jadhav, H. B., Gogate, P. R., & Annapure, U. S. (2022) · Catalysis in Green Chemistry and Engineering · doi:10.1615/catalgreenchemeng.2022043648
The Safety and Feasibility of Mediterranean-Ketogenic Dietary Interventions on Gut Health in Parkinson’s Disease: A Protocol for an Open-label, Randomized, Crossover Design Clinical Trial (KIM Trial)Preprint
Keymanesh, S., Tosefsky, K. N., Lam, J. S. T., Metcalfe‐Roach, A., Uzelman, P., Sacheli, M., Tetzlaff, W., Cohen, T. R., Wellington, C. L., Finlay, B. B., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2626068/v1
The Efficacy of Medium-Chain Triglyceride on the Prognosis and Outcome of Suspected COVID-19 Outpatients: A Randomized Controlled Trial
Setayesh, M., Zahedi-Neyestani, A., Asadikaram, G., Tajadini, H., Moghadari, M., Shahesmaeili, A., Jafarinejad‐Farsangi, S., Hasheminasab, F. S., & Amiri‐Ardekani, E. (2023) · Majallah-i dānishgāh-i ̒ulum-i pizishkī-i Kirmān. · doi:10.34172/jkmu.2023.17
Grouping of short alkyl-chain branched carboxylic acids for developmental toxicity
Colnot, T., & Dekant, W. (2024) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2024.105662
Metabolic Fate and Bioavailability of Coconut Nutrients
Fernando, M. G., Chen, J., Eslick, S., Castro, C. B., Garg, M. L., & Martins, R. N. (2024) · Springer eBooks · doi:10.1007/978-981-97-3976-9_3
The three years’ experience of long and very long chain fatty acid analysis
Gök, G., Bal, C., Akbulut, E. D., Uzdoğan, A., Yılmaz, G., & Erel, Ö. (2024) · Turkish Journal of Clinics and Laboratory · doi:10.18663/tjcl.1458978
Medium chain triglyceride-ketogenic diet elevates fasting blood glucose, lipid profile and liver enzymes but protects against high fat diet-induced changes
Dubo, A. B., Ejim, C. E., Farrau, U., Wandima, S., Ojoh, S. E., Sulaiman, A. I., Sada, A., & Daudu, H. (2025) · Journal of Pharmacy and Allied Medicine · doi:10.58985/jpam.2025.v03i01.28
Bioactive Fatty Acids
Gao, B., & Yu, L. (2025) · Royal Society of Chemistry eBooks · doi:10.1039/9781837674046-00118
Desenvolvimento e avaliação da eficácia clínica de formulação tópica para pele com dermatoporose em pacientes sadios e diabéticos
Pinto, J. R. (2024) · doi:10.47749/t/unicamp.2024.1490788
Medium-chain triglycerides and fractions in drug delivery systems
Zulfakar, M. H., & Ibrahim, S. I. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-26657-7.00019-2
Intensified Tricaprin Synthesis Using Multifrequency Ultrasound and Its Application as a Topical Drug Delivery System for Fungal Infections
Khasgiwale, V. N., Waghmare, J. T., & Gogate, P. R. (2025) · Industrial & Engineering Chemistry Research · doi:10.1021/acs.iecr.5c02112
Coconut oil blends
D’Amico, A., Buzzanca, C., Pilla, N., Gabrielli, P., Durazzo, A., Lucarini, M., & Stefano, V. A. D. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-24849-8.00005-8
Dietary Medium-Chain Triglycerides (MCTs) enhanced growth performance of nursery-reared milkfish Chanos chanos (Forsskål, 1775)
Batilong, L. S., Traifalgar, R. F. M., Ranara, C. T. B., Tanay, D. D., del Castillo, C. S., & Lumayno, S. D. P. (2025) · Israeli Journal of Aquaculture - Bamidgeh · doi:10.46989/001c.151734
Additional file 1 of Reactor microbiome enriches vegetable oil with n-caproate and n-caprylate for potential functionalized feed additive production via extractive lactate-based chain elongation
Contreras-Dávila, C. A., Zuidema, N., Buisman, C. J. N., & Strik, D. P. B. T. B. (2021) · Figshare · doi:10.6084/m9.figshare.17133028
Additional file 1 of A multimodal analytical method to simultaneously determine monoacetyldiacylglycerols, medium and long chain triglycerides in biological samples during routine lipidomics
Manful, C. F., Pham, T. H., Spicer, H., & Thomas, R. H. (2022) · Figshare · doi:10.6084/m9.figshare.19746122
Frying Stability of Virgin Coconut Oil and Medium‐Chain Triglyceride Blends: A Comparative Analysis
Mayookha, V. P., Uvais, V. C. M., Ramkumar, S., Sharma, K. A., & Kumar, G. S. (2025) · Journal of the American Oil Chemists Society · doi:10.1002/aocs.70017
Associations of lipids with diseases in large cohort studies and randomized trials
Kaur, R. P., & Palagati, K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-19116-9.00040-3
Both the type and amount of triglycerides influence the bioavailability of fat-soluble vitamins in mice
Berthomé, A., Aoud, A. E., Marze, S., Sabran, C., Vairo, D., & Reboul, E. (2026) · Food & Function · doi:10.1039/d5fo03891j
Application of response surface methodology for the preparation of modified dry water and evaluation of its explosion suppression performance
Yan, Z., & Zhao, W. (2026) · Particulate Science And Technology · doi:10.1080/02726351.2026.2613001
Nutritional assessment and lipid profile in rats fed a diet supplemented with sunflower oil and coconut oil
Yazit, S. M., Soualem, Z., Meziane, R. K., & Chabane-Sari, D. (2026) · Studia Biologica · doi:10.30970/sbi.2001.864
Biodisponibilité nutritionnelle de systèmes colloïdaux riches en acides gras polyinsaturés : études in vivo et in vitro
Couëdelo, L. (2011) · theses.fr (ABES) · doi:10.70675/6c367a1fz2a27z4aa1z9889z4d82752e992f
Élaboration de nanocapsules par polymérisation radicalaire contrôlée à partir d’un tensioactif réactif dérivé du dextrane
Ramirez, L. M. F. (2016) · doi:10.70675/84e6b9e7z5832z4327za356z83a23347a254
Impact de l'acide octanoïque alimentaire sur l'octanoylation de la Ghréline, chez le rat
Lemarié, F. L. (2016) · doi:10.70675/e882787az2359z4f02z8225z49a146903f2e
Synthèse enzymatique de phospholipides structurés riches en DHA
Hubert, F. (2018) · theses.fr (ABES) · doi:10.70675/75d60b69z9498z4a37za5e0zf91da04c099f
Formulation of Personalized, Fortified Beverage Nanoemulsions for Space Exploration with Omega-3 Polyunsaturated Fatty Acids
Schmidt, S., Fisk, I. D., Yang, N., Saarela, M., & Hessel, V. (2026) · ACS Food Science & Technology · doi:10.1021/acsfoodscitech.5c01291
Effect of glucose on medium chain triglyceride induced ketosis in healthy adults in a randomized, double-blind, controlled study
Frenser, M., Fobker, M., Feuerborn, R., Marquardt, T., & Fischer, T. (2026) · Scientific Reports · doi:10.1038/s41598-026-47702-4
A novel SonoVap for efficient and rapid tricaprylin synthesis
Huang, C., Liu, C., & Zhang, Q. (2026) · Chemical Engineering and Processing - Process Intensification · doi:10.1016/j.cep.2026.110859
Substrate Protein Enrichment of Black Soldier Fly ( Hermetia illucens ) Larvae for Diets of Olive Flounder ( Paralichthys olivaceus )
Jeong, S.-M., Min, B. H., Bae, J., 김민기, Hur, S. W., Park, K., & Kim, K. (2026) · Aquaculture Nutrition · doi:10.1155/anu/4780779
Crystallization of the Coconut Oil at the Oil/Water Interface: Impact of Monoglycerides and Sodium Caseinate
Obuchi, R., Fukai, K., Kameyama, R., Miyamae, T., Kaneko, W., Isaka, T., & Hanazawa, T. (2026) · The Journal of Physical Chemistry C · doi:10.1021/acs.jpcc.6c02528
Sulfonated reduced graphene oxide as a reusable acid nanocatalyst for medium chain triglyceride production
Gigi, A. A., Anilkumar, K., & Ragavan, K. V. (2026) · Journal of the Indian Chemical Society · doi:10.1016/j.jics.2026.103008
Gastrointestinal issues predominate among side effects of medium-chain triglyceride consumption in humans
Scheller, M., Frenser, M., Valembois, J., & Fischer, T. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1829954
C8 medium chain triglycerides benefit energy metabolism and modulate inflammatory lipids in cats with chronic kidney disease
Gordon, B. N., Panickar, K. S., Hollar, R. L., Tavener, S. K., Jewell, D. E., & Jackson, M. I. (2026) · Journal of Animal Science · doi:10.1093/jas/skag193
Effect of Medium Chain Fatty Acids on Body Composition in Individuals with Overweight and Obesity: A Systematic Review and Meta‐Analysis
Minamida, M., Nakajima, H., Okada, H., Kuramoto, N., Nakanishi, N., Hamaguchi, M., & Fukui, M. (2026) · Obesity Reviews · doi:10.1111/obr.70230
Oil chain length modulates the microscopic interfacial digestion and physiological feedback of oil in water emulsions
Wang, X., Zhang, W., Shao, J., Xu, X., & Zhao, X. (2026) · Food Research International · doi:10.1016/j.foodres.2026.120920
Triacylglycerol fatty acid composition modulates ATGL regioselectivity and diacylglycerol outputPreprint
Egger, N. B., Züllig, T., Gruber, K. F., Gruber, C. C., Radner, F. P. W., & Sahrawat, A. S. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.09.757750
Nutraceutical potential of caprine milk products: Emerging cardiometabolic health perspectives
Hans, S., Sioriki, E., Demuru, M., Zabetakis, I., & Lordan, R. (2026) · Food and Humanity · doi:10.1016/j.foohum.2026.101587

Authors: Marten, B., Pfeuffer, M., & Schrezenmeir, J.
Corresponding author: Pfeuffer, Maria
ORCID: Schrezenmeir, Jürgen
Venue: International Dairy Journal
Publisher: Elsevier BV
Published: 2006-11
Volume: 16
Issue: 11
Pages: 1374-1382
ISSN: 0958-6946 (ISSN-L)
DOI: 10.1016/j.idairyj.2006.06.015
OpenAlex: W2010109211
Cited by: 456
References: 85
Citations by year: 2026: 16 · 2025: 20 · 2024: 22 · 2023: 28 · 2022: 43 · 2021: 39 · 2020: 47 · 2019: 28 · 2018: 26 · 2017: 36 · 2016: 34 · 2015: 17 · 2014: 11 · 2013: 21 · 2012: 15
FWCI: 5.27
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: International Dairy Journal (publishedVersion)
OpenAgrar (submittedVersion)
Topics: Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Life Sciences › Agricultural and Biological Sciences › Food Science › Coconut Research and Applications
Keywords: medium-chain triglycerides, medium-chain fatty acids, coconut oil, milk fat, fatty acid metabolism, adipose tissue, PPARγ, lipoprotein secretion, postprandial triglycerides, insulin sensitivity, glucose metabolism, pro-inflammatory effects, hepatotoxicity, intestinal injury, fat loss

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Medium-chain triglycerides

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks