The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Magnetic nanocellulose alginate hydrogel beads as potential drug delivery system
Abstract
Magnetic nanocellulose alginate hydrogel beads are produced from the assembly of alginate and magnetic nanocellulose (m-CNCs) as a potential drug delivery system. The m-CNCs were synthesized from cellulose nanocrystals (CNCs) that were isolated from rice husks (RH) by co-precipitation method and were incorporated into alginate-based hydrogel beads with the aim of enhancing mechanical strength and regulating drug release behavior. Ibuprofen was chosen as a model drug. The prepared CNCs, m-CNCs and the alginate hydrogel beads were characterized by various physicochemical techniques such as Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscope (SEM) and vibrating sample magnetometer studies (VSM). Besides the magnetic property, the presence of m-CNCs increased the integrity of the alginate hydrogel beads and the swelling percentage. The drug release study exhibited a controlled release profiles and based on the drug release data, the drug release mechanism was analyzed and discussed based on mathematical models such as Korsmeyer-Peppas and Peppas-Sahlin.
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Cites
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Cited by
Development of alginate-based hydrogels: Crosslinking strategies and biomedical applications
Tan, J., Luo, Y., Guo, Y., Zhou, Y., Liao, X., Li, D., Lai, X., & Liu, Y. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124275 · Cited by 308
Production of Nanocellulose and Its Applications in Drug Delivery: A Critical Review
Salimi, S., Sotudeh-Gharebagh, R., Zarghami, R., Chan, S. Y., & Yuen, K. H. (2019) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.9b02744 · Cited by 268
Recent advances in colon drug delivery systems
Arévalo-Pérez, R., Maderuelo, C., & Lanao, J. M. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.09.026 · Cited by 179
Nanocellulose in targeted drug delivery: A review of modifications and synergistic applications
Babaei-Ghazvini, A., Patel, R., Vafakish, B., Yazdi, A. F. A., & Acharya, B. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135200 · Cited by 68
Metadata
- Authors
- Supramaniam, J., Adnan, R., Mohd Kaus, N. H., & Bushra, R.
- Venue
- International Journal of Biological Macromolecules
- Publisher
- Elsevier BV
- Published
- 2018-10
- Volume
- 118
- Issue
- Pt A
- Pages
- 640-648
- ISSN
- 0141-8130 (ISSN-L)
- OpenAlex
- W2807876330
- Cited by
- 282
- References
- 39
- FWCI
- 7.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- Supramaniam, J., Adnan, R., Mohd Kaus, N. H., & Bushra, R. (2018). Magnetic nanocellulose alginate hydrogel beads as potential drug delivery system. International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2018.06.043
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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