Mechanisms of solute release from porous hydrophilic polymers
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When n = 0.45 release order refers to be Fickian, but when 0.45<n<1, the release mechanism is termed as non-Fickian.
“When n = 0.45 release order refers to be Fickian, but when 0.45<n<1, the release mechanism is termed as non-Fickian.”
Cites
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- Authors
- Korsmeyer, R. W., Gurny, R., Doelker, E., Buri, P., & Peppas, N. A.
- Affiliations
- Purdue University West Lafayette (US)
- University of Geneva (CH)
- Corresponding author
- Peppas, Nikolaos A.
- ORCID
- Peppas, Nikolaos A.
- Venue
- International Journal of Pharmaceutics
- Publisher
- Elsevier BV
- Published
- 1983-05
- Volume
- 15
- Issue
- 1
- Pages
- 25-35
- ISSN
- 0378-5173 (ISSN-L)
- OpenAlex
- W1977072597
- Cited by
- 5,258
- References
- 12
- Citations by year
- 2026: 384 · 2025: 307 · 2024: 295 · 2023: 308 · 2022: 317 · 2021: 304 · 2020: 340 · 2019: 275 · 2018: 243 · 2017: 272 · 2016: 249 · 2015: 246 · 2014: 276 · 2013: 240 · 2012: 234
- FWCI
- 4.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Pharmaceutics (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Drug Solubulity and Delivery Systems
- Keywords
- solute release, polyvinyl alcohol, degree of hydrolysis, poly(N-vinyl-2-pyrrolidone), polyethylene glycol, potassium chloride, phenylpropanolamine hydrochloride, bovine serum albumin, release profile, polymer swelling, polymer dissolution, drug release mechanism
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