The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Macrophage roles following myocardial infarction
Open accessAbstract
Following myocardial infarction (MI), circulating blood monocytes respond to chemotactic factors, migrate into the infarcted myocardium, and differentiate into macrophages. At the injury site, macrophages remove necrotic cardiac myocytes and apoptotic neutrophils; secrete cytokines, chemokines, and growth factors; and modulate phases of the angiogenic response. As such, the macrophage is a primary responder cell type that is involved in the regulation of post-MI wound healing at multiple levels. This review summarizes what is currently known about macrophage functions post-MI and borrows literature from other injury and inflammatory models to speculate on additional roles. Basic science and clinical avenues that remain to be explored are also discussed.
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Cites
New functions for the matrix metalloproteinases in cancer progression
Egeblad, M., & Werb, Z. (2002) · Nature Reviews Cancer · doi:10.1038/nrc745 · Cited by 6,108
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Visse, R., & Nagase, H. (2003) · Circulation Research · doi:10.1161/01.res.0000070112.80711.3d · Cited by 4,575
Secretory products of macrophages.
Nathan, C. F. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112815 · Cited by 2,615
Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960
The many faces of macrophage activation
Mosser, D. M. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.0602325 · Cited by 1,902 · cited 1×
“Because we now have true and reliable markers of macrophage activation (Table 1), studies that characterize activation patterns post-MI will be forthcoming [48].”
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
Duffield, J. S., Forbes, S. J., Constandinou, C. M., Clay, S., Partolina, M., Vuthoori, S., Wu, S., Lang, R., & Iredale, J. P. (2005) · Journal of Clinical Investigation · doi:10.1172/jci200522675 · Cited by 1,649
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“• Can macrophages be used to target drug therapy to the MI site? Several groups have proposed using macrophages to target drug delivery, and whether this strategy will be effective remains to be determined [6,90,95,165,166].”
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Cited by
Macrophage plasticity and polarization in tissue repair and remodelling
Mantovani, A., Biswas, S. K., Galdiero, M. R., Sica, A., & Locati, M. (2013) · The Journal of Pathology · doi:10.1002/path.4133 · Cited by 2,384
Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease
Fan, D., Takawale, A., Lee, J., & Kassiri, Z. (2012) · Fibrogenesis & Tissue Repair · doi:10.1186/1755-1536-5-15 · Cited by 814
Jung, M., Ma, Y., Iyer, R. P., DeLeon-Pennell, K. Y., Yabluchanskiy, A., Garrett, M. R., & Lindsey, M. L. (2017) · Basic Research in Cardiology · doi:10.1007/s00395-017-0622-5 · Cited by 452
Self-citationUse of Mesenchymal Stem Cells for Therapy of Cardiac Disease
Karantalis, V., & Hare, J. M. (2015) · Circulation Research · doi:10.1161/circresaha.116.303614 · Cited by 425
Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair
Harel-Adar, T., Mordechai, T. B., Amsalem, Y., Feinberg, M. S., Leor, J., & Cohen, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015623108 · Cited by 362
Metadata
- Authors
- Lambert, J. M., Lopez, E. F., & Lindsey, M. L.
- Venue
- International Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2008-11
- Volume
- 130
- Issue
- 2
- Pages
- 147-158
- ISSN
- 0167-5273 (ISSN-L)
- OpenAlex
- W1994029289
- Cited by
- 339
- References
- 13
- FWCI
- 9.90
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
