Review of epidemiology and management of atrial fibrillation in developing countries
Abstract
Background Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia. In developing countries, AF is a growing public health problem with the epidemiologic transition from communicable to non-communicable diseases. However, relatively little is known about AF in the developing world. The aim of this review is to examine in developing countries the prevalence, associated medical conditions and management of AF.Methods A literature search was conducted via MEDLINE and EMBASE (1990-2012).Results Seventy studies were included in the review. The prevalence of AF in the general population ranged from 0.03% to 1.25%, while the prevalence of AF in hospital-based studies varied from 0.7% to 55.7%. Prevalence of AF in Africa was lower than in other regions. The most common conditions associated with AF were hypertension (10.3%-71.9%) and valvular heart disease (5.6%-66.3%). The prevalence of stroke in patients with AF ranged from 6.7% to 27%. The utilization of anticoagulants was highly variable (2.7%-72.7%). Approximately half of the patients with AF using warfarin had therapeutic International Normalized Ratios (INR). There was a high prevalence of use of rate control therapies (55.3%-87.3%).Conclusions The limited studies available suggest that in the developing world there is a significant prevalence of AF, which is predominantly associated with hypertension and valvular heart disease, and carries a risk of stroke. Highly variable use of anticoagulants may be related to different health care and socioeconomic settings. More studies are needed to improve understanding of the epidemiology and management of AF in developing countries.
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Metformin may even lower long-term stroke risk.
“and may even lower long-term stroke risk.”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [13]
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Flagged first, then by citations
Cited by
Sorted by citations
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
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- Authors
- Nguyen, T. N., Hilmer, S. N., & Cumming, R. G.
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Nguyen, Tu N.
- Venue
- International Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2013-09
- Volume
- 167
- Issue
- 6
- Pages
- 2412-2420
- ISSN
- 0167-5273 (ISSN-L)
- OpenAlex
- W1966629336
- Cited by
- 139
- References
- 118
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 4 · 2023: 15 · 2022: 8 · 2021: 20 · 2020: 13 · 2019: 10 · 2018: 11 · 2017: 13 · 2016: 13 · 2015: 7 · 2014: 10 · 2013: 7
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
- Keywords
- atrial fibrillation, developing countries, prevalence, hypertension, valvular heart disease, stroke risk, anticoagulation, warfarin, epidemiology, health care utilization
- MeSH terms
- Anticoagulants, Atrial Fibrillation, Developing Countries, Hospitalization, Humans, Warfarin, Disease Management
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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