Cited by 139Atrial Fibrillation Management and OutcomesAcute Ischemic Stroke ManagementCardiovascular and Diving-Related Complications

Review of epidemiology and management of atrial fibrillation in developing countries

Nguyen, Tu N., Hilmer, Sarah N., Cumming, Robert G.·2013·International Journal of Cardiology

Abstract

Background Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia. In developing countries, AF is a growing public health problem with the epidemiologic transition from communicable to non-communicable diseases. However, relatively little is known about AF in the developing world. The aim of this review is to examine in developing countries the prevalence, associated medical conditions and management of AF.Methods A literature search was conducted via MEDLINE and EMBASE (1990-2012).Results Seventy studies were included in the review. The prevalence of AF in the general population ranged from 0.03% to 1.25%, while the prevalence of AF in hospital-based studies varied from 0.7% to 55.7%. Prevalence of AF in Africa was lower than in other regions. The most common conditions associated with AF were hypertension (10.3%-71.9%) and valvular heart disease (5.6%-66.3%). The prevalence of stroke in patients with AF ranged from 6.7% to 27%. The utilization of anticoagulants was highly variable (2.7%-72.7%). Approximately half of the patients with AF using warfarin had therapeutic International Normalized Ratios (INR). There was a high prevalence of use of rate control therapies (55.3%-87.3%).Conclusions The limited studies available suggest that in the developing world there is a significant prevalence of AF, which is predominantly associated with hypertension and valvular heart disease, and carries a risk of stroke. Highly variable use of anticoagulants may be related to different health care and socioeconomic settings. More studies are needed to improve understanding of the epidemiology and management of AF in developing countries.

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Crossref · 10.1016/j.ijcard.2013.01.184

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Authors
Nguyen, T. N., Hilmer, S. N., & Cumming, R. G.
Affiliations
The University of Sydney (AU)
Corresponding author
Nguyen, Tu N.
Venue
International Journal of Cardiology
Publisher
Elsevier BV
Published
2013-09
Volume
167
Issue
6
Pages
2412-2420
ISSN
0167-5273 (ISSN-L)
OpenAlex
W1966629336
Cited by
139
References
118
Citations by year
2026: 2 · 2025: 5 · 2024: 4 · 2023: 15 · 2022: 8 · 2021: 20 · 2020: 13 · 2019: 10 · 2018: 11 · 2017: 13 · 2016: 13 · 2015: 7 · 2014: 10 · 2013: 7
FWCI
2.11
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
Keywords
atrial fibrillation, developing countries, prevalence, hypertension, valvular heart disease, stroke risk, anticoagulation, warfarin, epidemiology, health care utilization
MeSH terms
Anticoagulants, Atrial Fibrillation, Developing Countries, Hospitalization, Humans, Warfarin, Disease Management

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