Cited by 65Atrial Fibrillation Management and OutcomesCardiac Arrhythmias and TreatmentsCardiac electrophysiology and arrhythmias

Vagal atrial fibrillation: What is it and should we treat it?

Carpenter, Alexander, Frontera, Antonio, Bond, Richard, Duncan, Edward, Thomas, Glyn·2015·International Journal of Cardiology

Abstract

Vagal atrial fibrillation (AF) remains an under-recognised entity, affecting younger patients often with structurally normal hearts. Although there remains no universal definition or diagnostic criteria, in this review we describe recognised triggers and associated features, including a well-established association with athletic training. We explore potential mechanisms, including the role of the autonomic nervous system and ganglionated plexi in initiating and maintaining arrhythmia. We discuss the limited evidence base addressing the question of progression to persistent AF, and debate the merits of anti-arrhythmic treatment, as well as uncertainty regarding the risk of stroke. Differences in suggested pharmacological therapy are highlighted and as is the emerging promise of radiofrequency catheter ablation as a therapeutic option. As we recognise the emerging burden of vagal AF, we hope to explore the important similarities and differences crucial to developing our understanding of the disorder, and highlight some significant questions which remain unanswered.

Integrity signals

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Crossref · 10.1016/j.ijcard.2015.08.108

Cites

137 of 137 references verified0 citation errors · 0 not checkable

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  • Exercise-related increases in sympathetic tone in endurance athletes could also be predisposing factors for AF.

    “Exercise-related increases in sympathetic tone in endurance athletes could also be predisposing factors for AF [58,59].”

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Authors
Carpenter, A., Frontera, A., Bond, R., Duncan, E., & Thomas, G.
Affiliations
University Hospitals Bristol NHS Foundation Trust (GB)
Corresponding author
Carpenter, Alexander
Venue
International Journal of Cardiology
Publisher
Elsevier BV
Published
2015-12
Volume
201
Pages
415-421
ISSN
0167-5273 (ISSN-L)
OpenAlex
W1797686712
Cited by
65
References
137
Citations by year
2026: 6 · 2025: 7 · 2024: 4 · 2023: 6 · 2022: 8 · 2021: 6 · 2020: 8 · 2019: 7 · 2018: 4 · 2017: 4 · 2016: 5
FWCI
0.75
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords
paroxysmal atrial fibrillation, sports training, autonomic nervous system, ganglionated plexi, arrhythmia triggers, antiarrhythmic therapy, stroke risk, radiofrequency catheter ablation, structurally normal heart
MeSH terms
Anti-Arrhythmia Agents, Atrial Fibrillation, Humans, Risk Factors, Vagus Nerve, Treatment Outcome, Catheter Ablation

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