Probiotic therapy with Saccharomyces boulardii for heart failure patients: A randomized, double-blind, placebo-controlled pilot trial
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Increased FMO3 expression is associated with decreased kidney function in mice.
“another recent study also observed increased FMO3 expression associated with decreased kidney function in mice, suggesting genetic impact on plasma TMAO variability in specific settings such as decreased renal function205.”
From Dietary metabolism, the gut microbiome, and heart failure (2019) · cites this paper as [205]
Cites
Endotoxin and immune activation in chronic heart failure: a prospective cohort study
Niebauer, J., Volk, H.-D., Kemp, M., Dominguez, M., Schumann, R. R., Rauchhaus, M., Poole-Wilson, P. A., Coats, A. J., & Anker, S. D. (1999) · The Lancet · doi:10.1016/s0140-6736(98)09286-1 · Cited by 877 · see citing works
Khalesi, S., Sun, J., Buys, N., & Jayasinghe, R. (2014) · Hypertension · doi:10.1161/hypertensionaha.114.03469 · Cited by 516 · see citing works
Inflammatory Cytokines in Heart Failure: Mediators and Markers
Gullestad, L. L., Ueland, T., Vinge, L. E., Finsen, A. V., Yndestad, A., & Aukrust, P. (2012) · Cardiology · doi:10.1159/000338166 · Cited by 350 · see citing works
Intestinal microbiota determine severity of myocardial infarction in rats
Lam, V., Su, J., Koprowski, S. L., Hsu, A., Tweddell, J. S., Rafiee, P., Gross, G. J., Salzman, N. H., & Baker, J. E. (2012) · The FASEB Journal · doi:10.1096/fj.11-197921 · Cited by 338 · see citing works
Gan, X. T., Ettinger, G., Huang, C. X., Burton, J. P., Haist, J. V., Rajapurohitam, V., Sidaway, J. E., Martin, G., Gloor, G. B., Swann, J. R., et al. (2014) · Circulation: Heart Failure · doi:10.1161/circheartfailure.113.000978 · Cited by 329 · see citing works
The importance of the gastrointestinal system in the pathogenesis of heart failure
Krack, A., Sharma, R., Figulla, H. R., & Anker, S. D. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi389 · Cited by 280 · see citing works
Sandek, A., Bjarnason, I., Volk, H., Crane, R., Meddings, J., Niebauer, J., Kalra, P., Buhner, S., Herrmann, R., Springer, J., et al. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2010.12.016 · Cited by 241 · see citing works
Selective Intestinal Decontamination in Advanced Chronic Heart Failure: A Pilot Trial
Conraads, V. M., Jorens, P. G., Clerck, L. S. D., van Saene, H. K., Ieven, M. M., Bosmans, J. M., Schuerwegh, A. J., Bridts, C. H., Wuyts, F. L., Stevens, W. J., et al. (2004) · European Journal of Heart Failure · doi:10.1016/j.ejheart.2003.12.004 · Cited by 110 · see citing works
LIN, P.-P., Hsieh, Y.-M., Kuo, W., et al. (2013) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2013.1524 · Cited by 63 · see citing works
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Dietary metabolism, the gut microbiome, and heart failure
Tang, W. H. W., Li, D. Y., & Hazen, S. L. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0108-7 · Cited by 789 · see citing works
Intersections Between Microbiome and Heart Failure: Revisiting the Gut Hypothesis
Nagatomo, Y., & Tang, W. H. W. (2015) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2015.09.017 · Cited by 259 · see citing works
The effect of probiotics on inflammatory biomarkers: A meta-analysis of randomized clinical trials
Milajerdi, A., Mousavi, S. M., Sadeghi, A., Salari-Moghaddam, A., Parohan, M., Larijani, B., & Esmaillzadeh, A. (2020) · European Journal of Nutrition · doi:10.1007/s00394-019-01931-8 · Cited by 123 · see citing works
- Authors
- Costanza, A. C., Moscavitch, S. D., Faria Neto, H. C. C., & Mesquita, E. T.
- Affiliations
- Universidade Federal Fluminense (BR)
- Instituto Oswaldo Cruz (BR)
- Corresponding author
- Moscavitch, Samuel D.
- Venue
- International Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2015-01
- Volume
- 179
- Pages
- 348-350
- ISSN
- 0167-5273 (ISSN-L)
- OpenAlex
- W1980567421
- Cited by
- 182
- References
- 9
- Citations by year
- 2026: 7 · 2025: 24 · 2024: 28 · 2023: 28 · 2022: 29 · 2021: 17 · 2020: 16 · 2019: 17 · 2018: 6 · 2017: 5 · 2016: 3 · 2015: 2
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- International Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Arca - Repositório Institucional da Fiocruz (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- Saccharomyces boulardii, probiotics, heart failure, gut microbiota, inflammation, cardiac remodeling, TNF-α, interleukin-6, adhesion molecules
- MeSH terms
- Double-Blind Method, Heart Failure, Humans, Pilot Projects, Saccharomyces, Probiotics
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