Anesthesia mode for cesarean delivery and maternal-infant bonding: a single-center cross-sectional study
Abstract
Background Mother-infant bonding is central to early infant development and maternal well-being. The mode of anesthesia for cesarean delivery may influence maternal recovery, early contact with the newborn, and the postpartum psychological experience. This study aimed to assess the association between mode of anesthesia for cesarean delivery and mother-infant bonding, and its relationship with risk of postpartum depression and early anxiety symptoms. Methods In this cross-sectional study, women were recruited 1 to 3 days after cesarean delivery at Soroka University Medical Center. Eligible participants had delivered a live-born singleton term infant. During hospitalization, participants completed validated questionnaires assessing mother-infant bonding, risk for postpartum depression, and early postpartum anxiety symptoms. Outcomes were compared between women who underwent cesarean delivery under general anesthesia and those who received neuraxial anesthesia. Multivariable logistic regression was used to examine whether anesthesia mode was independently associated with impaired bonding. Results A total of 366 women were included, of whom 96 underwent cesarean delivery under general anesthesia and 270 under neuraxial anesthesia. No significant between-group differences were found in mother-infant bonding outcomes. The impaired-bonding difference was borderline but not statistically significant. Risk for postpartum depression and early postpartum anxiety symptoms was low and comparable between groups. After adjustment for potential confounders, anesthesia mode was not independently associated with impaired mother-infant bonding. Conclusion In this cohort, anesthesia mode for cesarean delivery was not independently associated with impaired early mother-infant bonding. Risk for postpartum depression and early anxiety symptoms did not differ significantly between groups.
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Cites
Guidelines for the process of cross-cultural adaptation of self-report measures
Beaton, D. E., Bombardier, C., Guillemin, F., & Ferraz, M. B. (2000) · Spine · doi:10.1097/00007632-200012150-00014 · Cited by 14,542 · see citing works
ACOG Committee Opinion No. 757: Screening for Perinatal Depression
(2018) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000002927 · Cited by 771 · see citing works
The Postpartum Bonding Questionnaire: a validation
Brockington, I. F., Fraser, C., & Wilson, D. (2006) · Archives of Women's Mental Health · doi:10.1007/s00737-006-0132-1 · Cited by 568 · see citing works
Correlates of prenatal and postnatal mother-to-infant bonding quality: A systematic review
Tichelman, E., Westerneng, M., Witteveen, A. B., van Baar, A. L., van der Horst, H. E., de Jonge, A., Berger, M. Y., Schellevis, F. G., Burger, H., & Peters, L. L. (2019) · PLOS ONE · doi:10.1371/journal.pone.0222998 · Cited by 224 · see citing works
The validity of the Arabic Edinburgh Postnatal Depression Scale
Ghubash, R., Abou‐Saleh, M. T., & Daradkeh, T. K. (1997) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/bf00789142 · Cited by 192 · see citing works
Hakanen, H., Flykt, M. S., Sinervä, E., Nolvi, S., Kataja, E., Pelto, J., Karlsson, H., Karlsson, L., & Korja, R. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.06.048 · Cited by 125 · see citing works
Wittkowski, A., Vatter, S., Muhinyi, A., Garrett, C., & Henderson, M. (2020) · Clinical Psychology Review · doi:10.1016/j.cpr.2020.101906 · Cited by 121 · see citing works
Characteristics of women with different perinatal depression trajectories
Wikman, A., Axfors, C., Iliadis, S. I., Cox, J., Fransson, E., & Skalkidou, A. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24390 · Cited by 118 · see citing works
Grisbrook, M.-A., Dewey, D., Cuthbert, C. A., McDonald, S., Ntanda, H. N., Giesbrecht, G. F., & Letourneau, N. L. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19084900 · Cited by 99 · see citing works
Benton, M., Salter, A., Tape, N., Wilkinson, C., & Turnbull, D. (2019) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-019-2687-7 · Cited by 91 · see citing works
Lehnig, F., Nagl, M., Stepan, H., Wagner, B., & Kersting, A. (2019) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-019-2426-0 · Cited by 80 · see citing works
Gilden, J., Molenaar, N. M., Smit, A. K., Hoogendijk, W. J. G., Rommel, A., Kamperman, A. M., & Bergink, V. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9072291 · Cited by 60 · see citing works
Neuraxial and general anaesthesia for caesarean section
Watson, S. E., Richardson, A. L., & Lucas, D. N. (2022) · Best practice & research. Clinical anaesthesiology · doi:10.1016/j.bpa.2022.04.007 · Cited by 56 · see citing works
Yoshida, T., Matsumura, K., Tsuchida, A., Hamazaki, K., & Inadera, H. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.11.005 · Cited by 35 · see citing works
Hailemeskel, H. S., Kebede, A. B., Fetene, M. T., & Dagnaw, F. T. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.893505 · Cited by 26 · see citing works
Klapper‐Goldstein, H., Pariente, G., Wainstock, T., Dekel, S., Binyamin, Y., Battat, T. L., Broder, O. W., Kosef, T., & Sheiner, E. (2024) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-024-07715-8 · Cited by 25 · see citing works
Self-citationBina, R., & Harrington, D. (2017) · Maternal and Child Health Journal · doi:10.1007/s10995-017-2345-5 · Cited by 24 · see citing works
Tokuda, N., Kobayashi, Y., Tanaka, H., Sawai, H., Shibahara, H., Takeshima, Y., Shima, M., Kamijima, M., Yamazaki, S., Ohya, Y., et al. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.05.056 · Cited by 16 · see citing works
Nitahara, K., Hidaka, N., Sakai, A., Kido, S., & Kato, K. (2020) · Journal of Perinatal Medicine · doi:10.1515/jpm-2019-0412 · Cited by 15 · see citing works
The association between epidural analgesia during labor and mother-infant bonding
Binyamin, Y., Wainstock, T., Sheiner, E., Battat, T. L., Reuveni, I., Leibson, T., & Pariente, G. (2022) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2022.110795 · Cited by 11 · see citing works
Self-citationSelçuki, N. F. T., Bahat, P. Y., Turan, G., Aksoy, U. M., Bağcı, K., & Özdemir, İ. (2022) · Acta bio-medica dell'Ateneo parmense/Acta biomedica · doi:10.23750/abm.v93i1.12137 · Cited by 6 · see citing works
Anderson, M. S., Baldwin, S., Rayment‐Jones, H., & Challacombe, F. L. (2025) · Midwifery · doi:10.1016/j.midw.2025.104630 · Cited by 4 · see citing works
Shebelsky, R., Sadi, W., Heesen, P., Aber, R. N., Fein, S., Iluz‐Freundlich, D., Shmueli, A., Azem, K., Tamayev, I. R., Binyamin, Y., et al. (2023) · Anaesthesia Critical Care & Pain Medicine · doi:10.1016/j.accpm.2023.101315 · Cited by 4 · see citing works
Self-citationKaramanou, A., Varela, P., Nanou, C., & Δελτσίδου, Ά. (2022) · Enfermería Intensiva (English ed ) · doi:10.1016/j.enfie.2021.07.002 · Cited by 4 · see citing works
Effect of ethnic origin and newborn gender on mother–infant bonding
Brami, H., Sheiner, E., Wainstock, T., Battat, T. L., Reuveni, I., Leibson, T., & Pariente, G. (2025) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-025-08003-9 · Cited by 1 · see citing works
Self-citationMOTHER-INFANT BONDING IN PATIENTS WITH BIPOLAR DISORDER
Alptekin, F. B., Güngör, B. B., Öztürk, N., & Aydın, N. (2022) · Nöro Psikiyatri Arşivi · doi:10.29399/npa.27896 · Cited by 1 · see citing works
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- Authors
- Azbarga, A., Wainstock, T., Binyamin, Y., Sheiner, E., Reuveni, I., & Pariente, G.
- Affiliations
- Ben-Gurion University of the Negev (IL)
- Tel Aviv University (IL)
- Corresponding author
- Binyamin, Yair
- Venue
- International Journal of Obstetric Anesthesia
- Publisher
- Elsevier BV
- Published
- 2026-11
- Volume
- 68
- Pages
- 105224
- ISSN
- 0959-289X (ISSN-L)
- OpenAlex
- W7165782614
- Cited by
- 1
- References
- 26
- Citations by year
- 2026: 1
- FWCI
- 9.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- International Journal of Obstetric Anesthesia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Health Sciences › Medicine › Surgery › Anesthesia and Pain Management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- cesarean section, mother-infant bonding, postpartum depression, postpartum anxiety, general anesthesia, neuraxial anesthesia, early postpartum period
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