The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Micro-scale devices for transdermal drug delivery
Open accessAbstract
Skin makes an excellent site for drug and vaccine delivery due to easy accessibility, immuno-surveillance functions, avoidance of macromolecular degradation in the gastrointestinal tract and possibility of self-administration. However, macromolecular drug delivery across the skin is primarily accomplished using hypodermic needles, which have several disadvantages including accidental needle-sticks, pain and needle phobia. These limitations have led to extensive research and development of alternative methods for drug and vaccine delivery across the skin. This review focuses on the recent trends and developments in this field of micro-scale devices for transdermal macromolecular delivery. These include liquid jet injectors, powder injectors, microneedles and thermal microablation. The historical perspective, mechanisms of action, important design parameters, applications and challenges are discussed for each method.
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Cites
McAllister, D. V., Wang, P. M., Davis, S. P., Park, J.-H., Canatella, P. J., Allen, M. G., & Prausnitz, M. R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2331316100 · Cited by 859
Self-citationSilicon micromachined hollow microneedles for transdermal liquid transport
Gardeniers, H. J. G. E., Luttge, R., Berenschot, E. J. W., de Boer, M. J., Yeshurun, S. Y., Hefetz, M., van-t Oever, R., & van den Berg, A. (2003) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2003.820293 · Cited by 413
Cited by
Microneedles for drug and vaccine delivery
Kim, Y.-C., Park, J.-H., & Prausnitz, M. R. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.04.005 · Cited by 1,760
Self-citationAldawood, F. K., Andar, A., & Desai, S. (2021) · Polymers · doi:10.3390/polym13162815 · Cited by 499
Overcoming the skin permeation barrier: Challenges and opportunities
Vitorino, C., Sousa, J., & Pais, A. (2015) · Current Pharmaceutical Design · doi:10.2174/1381612821666150428124053 · Cited by 78
Miniaturized Needle Array‐Mediated Drug Delivery Accelerates Wound Healing
Samandari, M., Aghabaglou, F., Nuutila, K., Derakhshandeh, H., Zhang, Y., Endo, Y., Harris, S., Barnum, L., Kreikemeier‐Bower, C., Arab‐Tehrany, E., et al. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202001800 · Cited by 47
Functionalized Textile Based Therapy for the Treatment of Atopic Dermatitis
Wang, W., Hui, P., & Kan, C.-W. (2017) · Coatings · doi:10.3390/coatings7060082 · Cited by 22
Metadata
- Authors
- Arora, A., Prausnitz, M. R., & Mitragotri, S.
- Venue
- International Journal of Pharmaceutics
- Publisher
- Elsevier BV
- Published
- 2008-12
- Volume
- 364
- Issue
- 2
- Pages
- 227-236
- ISSN
- 0378-5173 (ISSN-L)
- OpenAlex
- W2159458195
- Cited by
- 464
- References
- 2
- FWCI
- 14.43
- Type
- journal article
- Language
- en
- Open access
- green
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- Arora, A., Prausnitz, M. R., & Mitragotri, S. (2008). Micro-scale devices for transdermal drug delivery. International Journal of Pharmaceutics. https://doi.org/10.1016/j.ijpharm.2008.08.032
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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