Alternative activation of macrophages: Immune function and cellular biology

Alternative activation of macrophages

Gordon, S. (2003) · Nature Reviews Immunology · doi:10.1038/nri978 · Cited by 6,189

Monocyte and macrophage heterogeneity

Gordon, S., & Taylor, P. R. (2005) · Nature Reviews Immunology · doi:10.1038/nri1733 · Cited by 5,190

STATs and Gene Regulation

Darnell, J. E. (1997) · Science · doi:10.1126/science.277.5332.1630 · Cited by 3,979

Autophagy in Health and Disease: A Double-Edged Sword

Shintani, T., & Klionsky, D. J. (2004) · Science · doi:10.1126/science.1099993 · Cited by 2,559

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

Sallusto, F., Cella, M., Danieli, C., & Lanzavecchia, A. (1995) · The Journal of Experimental Medicine · doi:10.1084/jem.182.2.389 · Cited by 2,501

Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages

Gutierrez, M. G., Master, S. S., Singh, S. B., Taylor, G. A., Colombo, M. I., & Deretic, V. (2004) · Cell · doi:10.1016/j.cell.2004.11.038 · Cited by 2,252

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes.

Dalton, D., Pitts-Meek, S., Keshav, S., Figari, I., Bradley, A., & Stewart, T. (1993) · Science · doi:10.1126/science.8456300 · Cited by 2,015

Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation

Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960

Identification of the haemoglobin scavenger receptor

Kristiansen, M., Graversen, J. H., Jacobsen, C., Sonne, O., Hoffman, H.-J., Law, S. K. A., & Moestrup, S. K. (2001) · Nature · doi:10.1038/35051594 · Cited by 1,712

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

Kaplan, M. H., Schindler, U., Smiley, S. T., & Grusby, M. J. (1996) · Immunity · doi:10.1016/s1074-7613(00)80439-2 · Cited by 1,629

Modulation of macrophage polarization by level-1 Yo-Yo intermittent recovery test in young football players

Chiu, C.-J., Chi, C., Hsieh, H.-R., Huang, Y., Wu, H., & Chen, Y.-J. (2018) · Medicine · doi:10.1097/md.0000000000012739 · Cited by 2

Melatonina sintetizada por microglias de cerebelo em cultura regula o processo de fagocitose

dos Santos, A. A. (2015) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.41.2015.tde-17072015-153623 · Cited by 2

Stem Cells in Wound Healing and Scarring

Vinaik, R., & Jeschke, M. G. (2022) · Springer eBooks · doi:10.1007/978-981-19-2655-6_4 · Cited by 1

Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPARγ

Cheng, W., Chao, S.-P., Zhao, F., Cai, H., Zeng, Z., Cao, J., Jin, Z., Deng, K., Hu, X., Wang, H., et al. (2024) · Inflammation Research · doi:10.1007/s00011-024-01875-8 · Cited by 1

Probiotic properties of Bacillus licheniformis HN318 and comparison of the effects of its bacterial cells and cultures on growth, immunity and disease resistance of hybrid grouper (Epinephelus polyphekadion♂ × Epinephelus fuscoguttatus♀)

Cao, Z., Yang, Q., Kang, A., Wang, G., Li, P., Qiu, G., Wang, J., Liu, C., & Sun, Y. (2025) · Frontiers in Marine Science · doi:10.3389/fmars.2025.1548955 · Cited by 1

Atrazine alters nitric oxide secretion and cytokines production in LPS-stimulated BalB/c mice, RAW264.7 macrophage and THP-1 cell lines

Abarikwu, S. O., Ezim, O. E., Costa, G. M. J., Lacerda, S. M. D. S. N., Valverde, T. M., Costa, V. V., Aruoren, O., Monye, V. E., Ndufeiya-Kumasi, L. C., & Charles, I. A. (2025) · Chemosphere · doi:10.1016/j.chemosphere.2025.144749 · Cited by 1

Mangiferin and oleocanthal in the modulation of oxidative stress in monocytes and macrophages

Sharma, R., Anthikapalli, N. V. A., Kushwaha, R., Ovsii, A., Rác, M., Pospı́šil, P., Tamasi, G., Magnani, A., Rossi, C., & Prasad, A. (2026) · RSC Advances · doi:10.1039/d6ra01563h · Cited by 1

Fructus Sophorae Enhances the Production of Prostaglandin E2and Tumor Necrosis Factor-α through Activation of MAPKs and PI3K/AKT Signaling Pathways in Murine Macrophages

Kang, Y., Han, M. H., Lee, M. H., Hong, S. H., Park, H., Jung, J., Lee, J., Lee, E., Kang, K. H., Kim, C. M., et al. (2013) · Journal of Life Science · doi:10.5352/jls.2013.23.11.1397 · Cited by 1

W zdrowiu i chorobie – mikroRNA w funkcjonowaniu mięśni szkieletowych

Romańczuk, K., Mierzejewski, B., Michalska, Z., & Florkowska, A. (2022) · Postępy Biochemii · doi:10.18388/pb.2021_419 · Cited by 1

Innate origins of multiple sclerosis pathogenesis: Implications for computer‐assisted design of disease‐modifying therapies

Stoy, N. S. (2011) · Drug Development Research · doi:10.1002/ddr.20477 · Cited by 1

Schistosomula

Gobert, G. N., & Nawaratna, S. S. K. (2016) · CRC Press eBooks · doi:10.1201/9781315368900-10 · Cited by 1

Generation of Multinucleated Giant Cells due to Leishmania (V.) braziliensis Infection

Rojas‐Jaimes, J., & Pelaez, L. M. C. (2023) · Pharmacognosy Journal · doi:10.5530/pj.2023.15.172

Inflammation and immune-mediated neurobehavioral alterations : a critical role for microglia

Lacabanne, C. (2018) · theses.fr (ABES) · doi:10.70675/41a4e2a3zdbb7z4aa0z899dz9553bb07954b · Cited by 1

SHIP and Tumour-Associated Macrophages

Ho, V. W., Hamilton, M. J., Kuroda, E., Rüschmann, J., Antignano, F., Lam, V., & Krystal, G. (2011) · Springer eBooks · doi:10.1007/978-1-4614-0662-4_10

Elucidating the Role of the Humoral Response in Mycobacterium tuberculosis infected Cynomolgus Macaques

Phuah, J. Y. (2013) · D-Scholarship@Pitt (University of Pittsburgh)

Regulación de la producción de citoquinas por patrones moleculares de la pared de hongos

Rueda, C. M. M. (2012) · UVaDOC UVaDOC University of Valladolid Documentary Repository (University of Valladolid) · doi:10.35376/10324/1024

Imunossenescência e Candida albicans: avaliação da capacidade fagocítica e produção intracelular de substâncias microbicidas por monócitos e macrófagos

Gardizani, T. P. (2014) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.25.2014.tde-14102014-092152

Aspectos inmunológicos de la gestación

Hanssens, S., Salzet, M., & Vinatier, D. (2013) · EMC - Ginecología-Obstetricia · doi:10.1016/s1283-081x(13)64079-5

Caracterització dels tipus d'activació de diferents poblacions de macròfags durant la pancreatitis aguda experimental i la seva relació amb la severitat del procés

Gea‐Sorlí, S. (2011) · DIGITAL.CSIC (Spanish National Research Council (CSIC))

Investigating Thiol-Dependent Processes in the Phagosome of Macrophages

Balce, D. R. (2014) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/26648

Increased sensitivity to ozone-induced injury and altered pulmonary mechanics in mice with chronic lung inflammation. effects of aging

Groves, A. M. (2013) · Rutgers University Community Repository (Rutgers University) · doi:10.7282/t3hh6hpc

Macrophage Activation and Differentiation with Cholesterol Crystals

Burrowes, H. M. (2012) · UC Research Repository (University of Canterbury) · doi:10.26021/7900

Novel insights in the physiological function of sialoadhesin as a downregulator of macrophage phagocytosis and its implications for viral infection

Baere, M. D. (2012) · Ghent University Academic Bibliography (Ghent University)

A Hybrid Approach for Separation of the Strong Adhesion Macrophages

Wang, P. (2013) · Journal of Information and Computational Science · doi:10.12733/jics20102542

Macrophage subpopulations in COPD

Dewhurst, J. A. (2015) · Research Explorer (The University of Manchester)

DEFINITION OF AN IN VITRO MODEL OF HUMAN MONOCYTE ACTIVATION REPRESENTATIVE OF THE DEFENSIVE INFLAMMATORY RESPONSE

Italiani, P. (2013) · Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · doi:10.13130/italiani-paola_phd2013-02-07

Consequences of IRF2BP2 Loss of Function in Mouse Development and Skeletal Muscle Regeneration

Ho, T. (2016) · uO Research (University of Ottawa) · doi:10.20381/ruor-5781

A Therapeutic Role for Galectins in Acute Inflammation?

Cooper, D. (2012) · ACS symposium series · doi:10.1021/bk-2012-1115.ch019

Human immunodeficiency virus -1 (HIV-1) –Transactivator of transcription protein (Tat) effects on Macrophage polarization

Sarwan, S. (2015) · Lu Zone Ul (Laurentian University)

Classical swine fever virus-Shimen infection upregulates SH3GLB1 expression in porcine alveolar macrophages

Hu, A., Li, X., He, J., Gong, X., Wu, Z., & Ning, P. (2019) · Biotechnology & Biotechnological Equipment · doi:10.1080/13102818.2018.1552839

The role of MSCS in immunoregulation of macrophages during osteogenesis

Huang, R. S. (2018) · Queensland University of Technology · doi:10.5204/thesis.eprints.123512

The Role of Interleukin-5 in Host Defense during Influenza Infection

Gorski, S. A. (2013) · doi:10.18130/v3wz35

Terapia génica anti-inflamatoria en el abordaje de la neurodegeneración dopaminérgica motora

Lockhart, E. F. (2020) · El Servicio de Difusión de la Creación Intelectual (National University of La Plata) · doi:10.35537/10915/97168

The role of endoplasmic reticulum stress in atherosclerosis

Ekta, M. B., Sukhorukov, V. N., Markin, A. M., Sobenin, I. A., & Orekhov, A. N. (2020) · Complex Issues of Cardiovascular Diseases · doi:10.17802/2306-1278-2020-9-4-88-94

High Expression of eIF4E Regulates Immune Cell Infiltration and Leads to Poor Prognosis in Breast CancerPreprint

Li, F., Sun, H., Li, Y., Bai, X., Dong, X., Zhao, N., Meng, J., Sun, B., & Zhang, D. (2021) · Research Square · doi:10.21203/rs.3.rs-168436/v1

A sustainable regional economic growth strategy for Ireland's Mid West : targets and policies

Buckley, M. (2011) · University of Limerick Institutional Repository (University of Limerick) · doi:10.34961/141

ALTERED PORCINE ALVEOLAR MACROPHAGE PHENOTYPE BY ALL-TRANS RETINOIC ACID AND ASCARIS SUUM INFECTION

Perry, T. L. (2011) · University Libraries (University of Maryland)

Proteasome Inhibitor Immunotherapy for the Epithelial to Mesenchymal Transition: Assessing the A549 Lung Cancer Cell Microenvironment and the Role of M1, M2a and M2c ‘Hydrocortisone-Polarised’ MacrophagesPreprint

Engür, S., & Dikmen, M. (2022) · Research Square · doi:10.21203/rs.3.rs-1068010/v1

Ação do fenetil éster do ácido cafeico (CAPE) em Leishmania (Leishmania) amazonensis

Mesquita, A. (2021) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.74.2021.tde-16022022-085049

Stem Cells in Wound Healing and Scarring

Vinaik, R., & Jeschke, M. G. (2022) · Springer eBooks · doi:10.1007/978-981-16-6016-0_4-1

Aspects immunologiques de la gestation

Hanssens, S., Salzet, M., & Vinatier, D. (2012) · EMC - Obstétrique · doi:10.1016/s0246-0335(12)52458-0

Type II Activation of Macrophages and Microglia: Roles in T cell biasing and experimental autoimmune encephalomyelitis

Stone, S. (2013) · doi:10.26686/wgtn.17005993

High expression of eIF4E regulates immune cell infiltration and leads to poor prognosis in breast cancerPreprint

Li, F., Sun, H., Li, Y., Bai, X., Dong, X., Zhao, N., Meng, J., Sun, B., & Zhang, D. (2021) · Research Square · doi:10.21203/rs.3.rs-168436/v2

Supplementary Table 3 from Basal-like Breast Cancer Cells Induce Phenotypic and Genomic Changes in Macrophages

Stewart, D. A., Yang, Y., Makowski, L., & Troester, M. A. (2023) · doi:10.1158/1541-7786.22517352

Supplementary Table 3 from Basal-like Breast Cancer Cells Induce Phenotypic and Genomic Changes in Macrophages

Stewart, D. A., Yang, Y., Makowski, L., & Troester, M. A. (2023) · doi:10.1158/1541-7786.22517352.v1

Regulation of T Cell Response in Inflammation from Killing to Healing

Kumari, S., & Rai, A. K. (2024) · Springer eBooks · doi:10.1007/978-981-97-0157-5_4

Immunostimulatory Mechanisms of Water Extracts of Cirsium nipponicum Leaves and Roots: TLR2/4-ROS-p38 and JNK Signaling Pathways Mediating NO Production and iNOS Expression in RAW264.7 Cells

Lee, S. H., Choi, J. W., Chio, H. J., Park, S. J., Hwang, J. H., Kim, Y.-S., Hwang, K., & Jeong, J. B. (2025) · Microbiology and Biotechnology Letters · doi:10.48022/mbl.2412.12007

Apricot Pectin Polysaccharide: Structure, Rheological Properties and Macrophage Immune ActivationPreprint

Zheng, D., Li, T., Zhao, P., Lu, J., Zhang, W., Wang, Q., Zhao, J., Li, P., & Chen, P. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5698640

Mecanismos fisiopatogénicos involucrados en la patología ósea de la Enfermedad de Gaucher

Mucci, J. M. (2014) · doi:10.35537/10915/44681

Additional file 2 of Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX1

Peng, J., Pan, J., Wang, H., Mo, J., Lan, L., & Peng, Y. (2022) · Figshare · doi:10.6084/m9.figshare.19589154

Additional file 1 of Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX1

Peng, J., Pan, J., Wang, H., Mo, J., Lan, L., & Peng, Y. (2022) · Figshare · doi:10.6084/m9.figshare.19589148

Additional file 3 of Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX1

Peng, J., Pan, J., Wang, H., Mo, J., Lan, L., & Peng, Y. (2022) · Figshare · doi:10.6084/m9.figshare.19589160

Additional file 4 of Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX1

Peng, J., Pan, J., Wang, H., Mo, J., Lan, L., & Peng, Y. (2022) · Figshare · doi:10.6084/m9.figshare.19589169

Characterization of the activation status of T lymphocyte subpopulations in peripheral blood from localized and diffused cutaneous leishmaniasis patients at the University of Gondar Hospital, Ethiopia

Dubie, T., Chanyalew, M., Deressa, T., Atnafu, A., Debebe, D. G., Wondmagegn, T., Adem, M., Tsehay, D., Woldemariam, M., Zewdie, M., et al. (2026) · BMC Infectious Diseases · doi:10.1186/s12879-026-13050-x

Rôle des mastocytes dans le développement de la rectite radique in vivo et la réponse endothéliale à l’irradiation in vitro

Blirando, K. (2011) · theses.fr (ABES) · doi:10.70675/cb854efaza561z40abzb004z0655152c38c4

Molecular thermodynamic aspects of dissipative structures in oncology, inflammatory and degenerative processes of Central Nervous System diseases

Vallée, A. (2017) · theses.fr (ABES) · doi:10.70675/e07edff7z4f56z4165z8ee2z475c4aafb600

Impact cérébral précoce de l'inhalation chez le rat, le tungstène comme contaminant émergent

Macé, L. (2021) · theses.fr (ABES) · doi:10.70675/c7da5a7czefe9z4aa7zaa25z91a53cbb43b9

Mechanisms of Microglial NLRP3 Inflammasome Activation by Methylmalonic Acid in Methylmalonic Acidemia

Sun, S., Sun, L., Su, Y., Li, A., Hu, L., & Li, Q. (2026) · Mediators of Inflammation · doi:10.1155/mi/1635641

Structural Characterization of Acidic Polysaccharides from Scutellaria baicalensis Georgi and Its Protection Against Acute Lung Injury

Liu, S., Li, J., Li, M., Mi, Y., Ke, J., Wang, J., Dong, H., & Wang, X. D. (2026) · Antioxidants · doi:10.3390/antiox15091056

Extended IL-4 priming of macrophages induces an antiviral state that restricts lymphocytic choriomeningitis virus replication

Banete, A., Barilo, J., Rauh, M. J., Banfield, B. W., & Basta, S. (2026) · Cytokine · doi:10.1016/j.cyto.2026.157215

Exploring Research Progress on Traditional Chinese Medicine Regulating the Lung Cancer Immune Microenvironment Based on the Theory of “Strengthening the Healthy Qi and Eliminating the Pathogenic Qi”

李, 昕. (2026) · Advances in Clinical Medicine · doi:10.12677/acm.2026.16103564

Structure of the IL4 receptor and signal transduction mechanism of IL4

Izuhara, K., Yang, G., Miyajima, A., Howard, M., & Harada, N. (1993) · Research in Immunology · doi:10.1016/s0923-2494(05)80007-0 · Cited by 13

Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease

Dyken, S. J. V., & Locksley, R. M. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-095906 · Cited by 743

Alternative Activation of Macrophages: An Immunologic Functional Perspective

Martinez, F. O., Helming, L., & Gordon, S. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132532 · Cited by 2,745

Alternative activation of macrophages: mechanism and functions

Gordon, S., & Martinez, F. O. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.007 · Cited by 4,197

Alternative activation of macrophages

Gordon, S. (2003) · Nature Reviews Immunology · doi:10.1038/nri978 · Cited by 6,189