Macrophage Polarization Comes of Age

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    Kelly, Jennifer, Khan, Aslam Ali, Yin, Jiyi, Ferguson, Thomas A., Apte, Rajendra S. · 2007 · Journal of Clinical Investigation
  2. Macrophages and Immunologic Inflammation of the Kidney
    Jeremy S. Duffield · 2010 · Seminars in Nephrology
  3. Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function
    Claire S. Whyte, Eileen Bishop, Dominik Rückerl, Silvia Gaspar-Pereira, Robert N. Barker, Judith E. Allen, Andrew Jackson Rees, Heather M. Wilson · 2011 · Journal of Leukocyte Biology
  4. Macrophage-Osteoclast Associations: Origin, Polarization, and Subgroups
    Yang Sun, Jiangbi Li, Xiaoping Xie, Feng Gu, Zhenjiang Sui, Ke Zhang, Tiecheng Yu · 2021 · Frontiers in Immunology
  5. M1 Means Kill; M2 Means Heal
    Klaus F. Ley · 2017 · The Journal of Immunology
  6. Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues
    Christopher D. Gregory, John D. Pound · 2010 · The Journal of Pathology
  7. Control and dysregulation of redox signalling in the gastrointestinal tract
    Eric L. Campbell, Sean P. Colgan · 2018 · Nature Reviews Gastroenterology & Hepatology
  8. The Role of Decidual Macrophages During Normal and Pathological Pregnancy
    Fen Ning, Huishu Liu, Gendie E. Lash · 2016 · American Journal of Reproductive Immunology
  9. Aging is not a disease: Distinguishing age-related macular degeneration from aging
    Daniel Ardeljan, Chi‐Chao Chan · 2013 · Progress in Retinal and Eye Research
  10. Neutrophils: important contributors to tumor progression and metastasis
    Swierczak, Agnieszka, Mouchemore, Kellie A., Hamilton, John A., Anderson, Robin L. · 2015 · Cancer and Metastasis Reviews
  11. Innate immune cell–epithelial crosstalk during wound repair
    Jennifer Catherine Brazil, Miguel Quirós, Asma Nusrat, Charles A. Parkos · 2019 · Journal of Clinical Investigation
  12. Integrin‐Mediated Interactions Control Macrophage Polarization in 3D Hydrogels
    Byung‐Hyun Cha, Su Ryon Shin, Jeroen Leijten, Yi‐Chen Li, Sonali Singh, Julie C. Liu, Nasim Annabi, Reza Abdi, Mehmet R. Dokmeci, Nihal Engin Vrana et al. · 2017 · Advanced Healthcare Materials
  13. Taming cancer by inducing immunity via dendritic cells
    Anna Karolina Palucka, Hideki Ueno, Joseph W. Fay, Jacques Banchereau · 2007 · Immunological Reviews
  14. Toll-Like Receptor-3-Activated Human Mesenchymal Stromal Cells Significantly Prolong the Survival and Function of Neutrophils
    Marco Antonio Cassatella, Federico Mosna, Alessandra Micheletti, Veronica Lisi, Nicola Tamassia, Caterina Cont, Federica Calzetti, Martin Pelletier, Giovanni Pizzolo, Mauro Krampera · 2011 · Stem Cells
  15. Tumor-associated macrophage, angiogenesis and lymphangiogenesis markers predict prognosis of non-small cell lung cancer patients
    Ilseon Hwang, Jeong Won Kim, Kris Ylaya, Eun Joo Chung, Haruhisa Kitano, Candice D. Perry, Jun Hanaoka, Junya Fukuoka, Joon‐Yong Chung, Stephen M. Hewitt · 2020 · Journal of Translational Medicine
  16. Microglial activation and progressive brain changes in schizophrenia
    Liliana Laskaris, Maria Angelique Di Biase, Ian Everall, Gursharan Chana, Arthur Christopoulos, Efstratios Stan Skafidas, Vanessa Cropley, Christos Pantelis · 2015 · British Journal of Pharmacology
  17. Serum Amyloid P Inhibits Fibrosis Through FcγR-Dependent Monocyte-Macrophage Regulation in Vivo
    A. Castano, Shuei-Liong Lin, T. Surowy, Brian T. Nowlin, Swathi A. Turlapati, T. Patel, A. Singh, Shawn S. Li, M. Lupher, J. Duffield · 2009 · Science Translational Medicine
  18. M1 and M2a Polarization of Human Monocyte-Derived Macrophages Inhibits HIV-1 Replication by Distinct Mechanisms
    Edana Cassol, Luca Cassetta, Chiara Rizzi, Massimo Alfano, Guido Poli · 2009 · The Journal of Immunology
  19. Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways
    Lolmede, Karine, Campana, Lara, Vezzoli, Michela, Bosurgi, Lidia, Tonlorenzi, Rossana, Clementi, Emilio, Bianchi, Marco E, Cossu, Giulio, Manfredi, Angelo A, Brunelli, Silvia et al. · 2009 · Journal of Leukocyte Biology
  20. Diverse Roles of Macrophages in Atherosclerosis: From Inflammatory Biology to Biomarker Discovery
    Ting Gui, Aiko Shimokado, Yujing Sun, Takashi Akasaka, Yasuteru Muragaki · 2012 · Mediators of Inflammation
  21. Modulating neurotoxicity through CX3CL1/CX3CR1 signaling
    Limatola, Cristina, Ransohoff, Richard M. · 2014 · Frontiers in Cellular Neuroscience
  22. Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages
    Jinglian Yan, Guodong Tie, Shouying Wang, Amanda A. Tutto, Natale DeMarco, Lyne Khair, Thomas G. Fazzio, Louis M. Messina · 2017 · Nature Communications
  23. Extracellular matrix scaffold devices for rotator cuff repair
    Kathleen A. Derwin, Stephen F. Badylak, Scott P. Steinmann, Joseph P. Iannotti · 2010 · Journal of Shoulder and Elbow Surgery
  24. Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study
    Elysia M. Hollams, Prue H. Hart, Barbara J. Holt, Michael Serralha, Faith Parsons, Nicholas Hubert de Klerk, Guicheng Zhang, Peter David Sly, Patrick G. Holt · 2011 · European Respiratory Journal
  25. Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of colorectal cancer
    Penglei Ge, Weiwei Wang, Lin Li, Gong Zhang, Zhiqiang Gao, Zhe Tang, Xiaowei Dang, Yang Wu · 2019 · Biomedicine & Pharmacotherapy
  26. Differential Macrophage Polarization in Male and Female BALB/c Mice Infected With Coxsackievirus B3 Defines Susceptibility to Viral Myocarditis
    Kang Li, Wei Xu, Qiang Guo, Zhenggang Jiang, Ping Wang, Yan Yue, Sidong Xiong · 2009 · Circulation Research
  27. The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity
    Sag, Duygu, Cekic, Caglar, Wu, Runpei, Linden, Joel, Hedrick, Catherine C. · 2015 · Nature Communications
  28. Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r–EGFP transgene reporter
    Fiona Rae, Kyra J. Woods, R. Tedjo Sasmono, Naomi Campanale, Darrin F. Taylor, Dmitry A. Ovchinnikov, Sean Michael Grimmond, David Arthur Hume, Sharon D. Ricardo, Melissa Helen Little · 2007 · Developmental Biology
  29. Pretreatment levels of peripheral neutrophils and leukocytes as independent predictors of overall survival in patients with American Joint Committee on Cancer Stage IV Melanoma: results of the EORTC 18951 Biochemotherapy Trial.
    H. Schmidt, S. Suciu, C. Punt, M. Gore, W. Kruit, P. Patel, D. Liénard, H. von der Maase, A. Eggermont, U. Keilholz · 2007 · Journal of Clinical Oncology
  30. Inflammatory bowel disease and intestinal cancer: a paradigm of the Yin–Yang interplay between inflammation and cancer
    Silvio Danese, Alberto Mantovani · 2010 · Oncogene
  31. M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis
    Jiwei Hou, Jingyan Shi, Ling Chen, Zhongyang Lv, Xiang Chen, Honghui Cao, Zou Xiang, Xiaodong Han · 2018 · Cell Communication and Signaling
  32. Generation and Characterization of Murine Alternatively Activated Macrophages
    Shelley B. Weisser, Keith W. McLarren, Etsushi Kuroda, Laura M. Sly · 2012 · Methods in molecular biology
  33. Macrophage Plasticity in Skeletal Muscle Repair
    Elena Rigamonti, Paola Zordan, Clara Sciorati, Patrizia Querini Rovere, Silvia Brunelli · 2014 · BioMed Research International
  34. The immunomodulatory properties of mesenchymal stem cells
    Ilaria Marigo, Francesco Dazzi · 2011 · Seminars in Immunopathology
  35. Solubilized extracellular matrix bioscaffolds derived from diverse source tissues differentially influence macrophage phenotype
    Dziki, Jenna L., Wang, Derek S., Pineda, Catalina, Sicari, Brian M., Rausch, Theresa, Badylak, Stephen F. · 2017 · Journal of Biomedical Materials Research Part A
  36. Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO
    Vidya Narayanaswami, Kenneth Dahl, Vadim Bernard‐Gauthier, Lee Josephson, Paul D. Cumming, Neil Vasdev · 2018 · Molecular Imaging
  37. Macrophage function in obesity-induced inflammation and insulin resistance
    Mario Lauterbach, Frank Thomas Wunderlich · 2017 · Pflügers Archiv - European Journal of Physiology
  38. Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages
    Bin Deng, Chin‐Wei Wang, Hildur H. Arnardottir, Yongsheng Li, Chien-Yee Cindy Cheng, Jesmond Dalli, Charles Nicholas Serhan · 2014 · PLoS ONE
  39. The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation
    Yaël Mamane, Chi‐Chung Chan, Geneviève Lavallée, Nicolas Morin, Lijing Xu, Jingqi Huang, Robert Gordon, Winston Thomas, John R. Lamb, Eric E. Schadt et al. · 2009 · Diabetes
  40. Anti-Infective Protective Properties of S100 Calgranulins
    Kenneth Hsu, Chantrakorn Champaiboon, Brian D. Guenther, Brent S. Sorenson, Ali Khammanivong, Karen F. Ross, Carolyn L. Geczy, Mark C. Herzberg · 2009 · Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
  41. Rapamycin unbalances the polarization of human macrophages to M 1
    Alessia Mercalli, Ines Calavita, Erica Dugnani, Antonio Citro, Elisa Cantarelli, Rita Nano, Raffaella Melzi, Paola Maffi, Antonio Secchi, Valeria Sordi et al. · 2013 · Immunology
  42. Expression profiles of miRNAs in polarized macrophages
    ZHANG, YINGYING, ZHANG, MENGYING, ZHONG, MIN, SUO, QIFENG, LV, KUN · 2013 · International Journal of Molecular Medicine
  43. Macrophage polarization to a unique phenotype driven by B cells
    Siew Cheng Wong, Anne‐Laure Puaux, Manesh Chittezhath, Irina N. Shalova, Tasneem Kajiji, Xiaojie Wang, Jean‐Pierre Abastado, Kong‐Peng Lam, Subhra Kumar Biswas · 2010 · European Journal of Immunology
  44. Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis
    Bernard Vandooren, Troy Noordenbos, Carmen A. Ambarus, Sarah Krausz, Tineke Cantaert, Nataliya G. Yeremenko, Maartje Boumans, René Lutter, Paul Peter Tak, Dominique Baeten · 2009 · Arthritis & Rheumatism
  45. New Lives Given by Cell Death: Macrophage Differentiation Following Their Encounter with Apoptotic Leukocytes during the Resolution of Inflammation
    Amiram Ariel, Charles Nicholas Serhan · 2012 · Frontiers in Immunology
  46. REVIEW ARTICLE: The Contribution of Macrophages to Normal and Pathological Pregnancies
    Takeshi Nagamatsu, Danny Joseph Schust · 2010 · American Journal of Reproductive Immunology
  47. Unique Expression of Suppressor of Cytokine Signaling 3 Is Essential for Classical Macrophage Activation in Rodents In Vitro and In Vivo
    Yu Liu, Keith N. Stewart, Eileen Bishop, Carylyn J. Marek, David Kluth, Andrew Jackson Rees, Heather M. Wilson · 2008 · The Journal of Immunology
  48. Blockade of Notch1 Signaling Alleviates Murine Lupus via Blunting Macrophage Activation and M2b Polarization
    Zhang, Weijuan, Xu, Wei, Xiong, Sidong · 2010 · The Journal of Immunology
  49. Macrophage polarization and HIV-1 infection
    Edana Cassol, Luca Cassetta, Massimo Alfano, Guido Poli · 2009 · Journal of Leukocyte Biology
  50. Neuro-immune crosstalk in CNS diseases
    Martin Kerschensteiner, Edgar Meinl, Reinhard Hohlfeld · 2008 · Neuroscience
  51. Chitosan drives anti-inflammatory macrophage polarisation and pro-inflammatory dendritic cell stimulation
    Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre 823, 4150-180-Porto, Portugal, Oliveira, MI, Santos, SG, Oliveira, MJ, Torres, AL, Barbosa, MA · 2012 · European Cells and Materials
  52. Matricellular Protein CCN1 Activates a Proinflammatory Genetic Program in Murine Macrophages
    Bai, Tao, Chen, Chih-Chiun, Lau, Lester F · 2010 · The Journal of Immunology
  53. Cyclooxygenase-2 Inhibition Blocks M2 Macrophage Differentiation and Suppresses Metastasis in Murine Breast Cancer Model
    Yi-Rang Na, Yi-Na Yoon, Da-In Son, Seung Hyeok Seok · 2013 · PLoS ONE
  54. Hemodynamic Stress, Inflammation, and Intracranial Aneurysm Development and Rupture: A Systematic Review
    Francesco Signorelli, Sapir Sela, Loreto Gesualdo, Sophie Chevrel, Félix Tollet, Cyril Pailler-Mattei, Leonello Tacconi, Francis Turjman, Angelo Vacca, David B. Schul · 2018 · World Neurosurgery
  55. Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune Pathways
    Kai Li, Shuai Qu, Xi Chen, Qiong Wu, Ming Shi · 2017 · International Journal of Molecular Sciences
  56. Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results
    David M. Hasan, Nohra Chalouhi, Pascal M. Jabbour, Tomoki N Hashimoto · 2012 · Journal of Neuroinflammation
  57. Evolving immunosuppressive microenvironment during human cervical carcinogenesis
    Akiko Kobayashi, VIVIAN K. WEINBERG, Teresa M. Darragh, Karen Smith‐McCune · 2008 · Mucosal Immunology
  58. Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses
    Brown, Kelly L, Poon, Grace F T, Birkenhead, Darlene, Pena, Olga M, Falsafi, Reza, Dahlgren, Claes, Karlsson, Anna, Bylund, Johan, Hancock, Robert E W, Johnson, Pauline · 2011 · The Journal of Immunology
  59. Immune Cell Phenotype and Function in Sepsis
    Thomas R. Rimmele, Didier M. Payen, Vincenzo Cantaluppi, John C. Marshall, Hernando Gómez, Alonso Gómez, Patrick T. Murray, John A. Kellum · 2015 · Shock
  60. Engagement of the Mannose Receptor by Tumoral Mucins Activates an Immune Suppressive Phenotype in Human Tumor‐Associated Macrophages
    Paola Allavena, Marcello Chieppa, Giuseppe Bianchi, Graziella Solinas, Marco Fabbri, Gordana Laškarin, Alberto Mantovani · 2010 · Journal of Immunology Research
  61. Modulation of macrophage activation and programming in immunity
    Guangwei Liu, Hui Yang · 2012 · Journal of Cellular Physiology
  62. Targeting IL-1 in depression
    Michael H. J. Maes, Cai Song, Raz Yirmiya · 2012 · Expert Opinion on Therapeutic Targets
  63. Macrophages, Wound Healing, and Fibrosis: Recent Insights
    Kate S. Smigiel, William C. Parks · 2018 · Current Rheumatology Reports
  64. Disequilibrium of M1 and M2 Macrophages Correlates with the Development of Experimental Inflammatory Bowel Diseases
    Wei Zhu, Jianbo Yu, Ying Nie, XueKui Shi, Yang Liu, Fujuan Li, Xiaoli Zhang · 2014 · Immunological Investigations
  65. Effect of the αGal Epitope on the Response to Small Intestinal Submucosa Extracellular Matrix in a Nonhuman Primate Model
    Kerry A. Daly, Ann M. Stewart‐Akers, Hidetaka Hara, Mohamed B. Ezzelarab, Cassandra E. Long, Kevin E. Cordero, Scott A. Johnson, David Ayares, David K.C. Cooper, Stephen F. Badylak · 2009 · Tissue Engineering Part A
  66. The Tumor Microenvironment: The Making of a Paradigm
    Isaac P. Witz · 2009 · Cancer Microenvironment
  67. Intratumoral Myeloid Cells Regulate Responsiveness and Resistance to Antiangiogenic Therapy
    Lee B. Rivera, David Meyronet, Valérie Hervieu, Mitchell J. Frederick, Emily K. Bergsland, Gabriele Bergers · 2015 · Cell Reports
  68. Interleukin-10 Promotes Pathological Angiogenesis by Regulating Macrophage Response to Hypoxia during Development
    Dru S. Dace, Aslam Khan, Jennifer Kelly, Rajendra S. Apte · 2008 · PLoS ONE
  69. Effect of Culture Conditions on the Phenotype of THP ‐1 Monocyte Cell Line
    Paulomi Bole Aldo, Vinicius Craveiro, Seth M. Guller, Gil Mor · 2013 · American Journal of Reproductive Immunology
  70. The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases
    Peter J. Wermuth, Sergio A. Jiménez · 2015 · Clinical and Translational Medicine
  71. The number and microlocalization of tumor-associated immune cells are associated with patient's survival time in non-small cell lung cancer
    F. Dai, Lun-Xu Liu, G. Che, Nanbin Yu, Q. Pu, Shangfu Zhang, Junliang Ma, Lin Ma, Z. You · 2010 · BMC Cancer
  72. Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics
    Rita A. Mukhtar, Onouwem Nseyo, Michael J. Campbell, Laura J. Esserman · 2010 · Expert Review of Molecular Diagnostics
  73. Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis
    Filip K. Świrski, Ralph Weissleder, Mikaël J. Pittet · 2009 · Arteriosclerosis Thrombosis and Vascular Biology
  74. The Immunomodulatory Roles of Macrophages at the Maternal—Fetal Interface
    Takeshi Nagamatsu, Danny Joseph Schust · 2010 · Reproductive Sciences
  75. Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Rα, IL-13Rα1, and γc regulates relative cytokine sensitivity
    Ilkka Junttila, Kiyoshi Mizukami, Harold L. Dickensheets, Martin Meier‐Schellersheim, Hidehiro Yamane, Raymond P. Donnelly, William E. Paul · 2008 · The Journal of Experimental Medicine
  76. The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair
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  77. Non-neuronal cells in amyotrophic lateral sclerosis — from pathogenesis to biomarkers
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  78. Interleukin-10 protects against atherosclerosis by modulating multiple atherogenic macrophage function
    Xinbing Han, William A. Boisvert · 2014 · Thrombosis and Haemostasis
  79. Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models
    Cristina Belgiovine, Ezia Bello, Manuela Liguori, Ilaria Craparotta, Laura Mannarino, Lara Paracchini, Luca Beltrame, Sergio Marchini, Carlos María Galmarini, Alberto Mantovani et al. · 2017 · British Journal of Cancer
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  82. What Differentiates Normal Lung Repair and Fibrosis?: Inflammation, Resolution of Repair, and Fibrosis
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  83. Macrophage Depletion Abates Porphyromonas gingivalis–Induced Alveolar Bone Resorption in Mice
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  98. The immune system and the repair of skeletal muscle.
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  100. Chrysin attenuates inflammation by regulating M1/M2 status via activating PPARγ
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