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Dysbiotic oral microbiota-derived kynurenine, induced by chronic restraint stress, promotes head and neck squamous cell carcinoma by enhancing CD8 + T cell exhaustion

Lou, F., Yan, L., Luo, S., Dong, Y., Xu, J., Kang, N., Wang, H., Liu, Y., Pu, J., Yang, B., et al. (2025) · Gut · doi:10.1136/gutjnl-2024-333479 · Cited by 39

Decreased gut microbiome-derived indole-3-propionic acid mediates the exacerbation of myocardial ischemia/reperfusion injury following depression via the brain-gut-heart axis

Mu, X., Feng, L., Wang, Q., Li, H., Zhou, H., Yi, W., & Sun, Y. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103580 · Cited by 35

Microbial metabolite-driven immune reprogramming in tumor immunotherapy: mechanisms and therapeutic perspectives

Lu, Y., Yuan, H., Liang, S., Li, D., Jiang, P., Wang, X., Zhang, K., & Liu, D. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1603658 · Cited by 41

Frontline Science: Tryptophan restriction arrests B cell development and enhances microbial diversity in WT and prematurely aging Ercc1−/Δ7 mice

van Beek, A. A., Hugenholtz, F., Meijer, B., Sovran, B., Perdijk, O., Vermeij, W. P., Brandt, R. M. C., Barnhoorn, S., Hoeijmakers, J. H. J., de Vos, P., et al. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.1hi0216-062rr · Cited by 36

Gut REG3γ-Associated Lactobacillus Induces Anti-inflammatory Macrophages to Maintain Adipose Tissue Homeostasis

Huang, Y., Qi, H., Zhang, Z., Wang, E., Yun, H., Yan, H., Su, L., Liu, Y., Tang, Z., Gao, Y., et al. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01063 · Cited by 38

Gut Microbiota Dysbiosis Is Not Independently Associated With Neurocognitive Impairment in People Living With HIV

Zhang, F., Yang, J., Ji, Y., Sun, M., Shen, J., Sun, J., Wang, J., Liu, L., Shen, Y., Zhang, R., et al. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.03352 · Cited by 35

Role of Gut Microbiota in the Pharmacological Effects of Natural Products

Pan, C., Qing-long, G., & Lu, N. (2019) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2019/2682748 · Cited by 37

Regulation of mononuclear phagocyte function by the microbiota at mucosal sites

Scott, N. A., & Mann, E. R. (2019) · Immunology · doi:10.1111/imm.13155 · Cited by 35

Microbial metabolite indole-3-propionic acid supplementation does not protect mice from the cardiometabolic consequences of a Western diet

Lee, D. M., Ecton, K. E., Trikha, S. R. J., Wrigley, S. D., Thomas, K. N., Battson, M. L., Wei, Y., Johnson, S. A., Weir, T. L., & Gentile, C. L. (2020) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00375.2019 · Cited by 36

The Aryl Hydrocarbon Receptor in Chronic Kidney Disease: Friend or Foe?

Mo, Y., Lu, Z., Wang, L., Ji, C., Zou, C., & Liu, X. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.589752 · Cited by 36

Aryl Hydrocarbon Receptor Plasma Agonist Activity Correlates With Disease Activity in Progressive MS

Tsaktanis, T., Beyer, T., Nirschl, L., Linnerbauer, M., Grummel, V., Bussas, M., Tjon, E. C., Mühlau, M., Korn, T., Hemmer, B., et al. (2020) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000000933 · Cited by 36

The metabolic regulation of Fuzhuan brick tea in high-fat diet-induced obese mice and the potential contribution of gut microbiota

Liu, D., Wang, J., Zeng, H., Zhou, F., Wen, B., Zhang, X.-N., Luo, Y. L., Wu, W., Huang, J., & Liu, Z. (2021) · Food & Function · doi:10.1039/d1fo02181h · Cited by 35

Tissue-Dependent Adaptations and Functions of Innate Lymphoid Cells

Murphy, J. M., Ngai, L., Mortha, A., & Crome, S. Q. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.836999 · Cited by 36

Molecular properties of postbiotics and their role in controlling aquaculture diseases

Sudhakaran, G., Guru, A., Haridevamuthu, B., Murugan, R., Arshad, A., & Arockiaraj, J. (2022) · Aquaculture Research · doi:10.1111/are.15846 · Cited by 41

Protective effects of konjac glucomannan on gut microbiome with antibiotic perturbation in mice

Mao, Y.-H., Xu, Y., Song, F., Wang, Z., Li, Y., Zhao, M., He, F., Tian, Z., & Yang, Y. (2022) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2022.119476 · Cited by 36

Butyrate, a typical product of gut microbiome, affects function of the AhR gene, being a possible agent of crosstalk between gut microbiome, and hepatic drug metabolism

Jourová, L., Anzenbacherová, E., Dostál, Z., Anzenbacher, P., Briolotti, P., Rigal, É., Daujat‐Chavanieu, M., & Gerbal‐Chaloin, S. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.109042 · Cited by 36

Recent Trends of Microbiota-Based Microbial Metabolites Metabolism in Liver Disease

Ganesan, R., Jeong, J., Kim, D. J., & Suk, K. T. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.841281 · Cited by 38

Immunomodulation by foods and microbes: Unravelling the molecular tango

Forde, B. M., Yao, L., Shaha, R., Murphy, S., Lunjani, N., & O’Mahony, L. (2022) · Allergy · doi:10.1111/all.15455 · Cited by 35

Additional file 1 of IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans

Mar, J. S., Ota, N., Pokorzynski, N. D., Peng, Y., Jaochico, A., Sangaraju, D., Skippington, E., Lekkerkerker, A., Rothenberg, M. E., Tan, M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22619468

Microbiota‐Derived Tryptophan Metabolites Activate Aryl Hydrocarbon Receptor and Induce IL‐10 Receptor Expression in Intestinal Epithelia

Alexeev, E. E., Lanis, J. M., Schwisow, K. D., Kominsky, D. J., & Colgan, S. P. (2016) · The FASEB Journal · doi:10.1096/fasebj.30.1_supplement.57.2 · Cited by 6

A42 MICROBIAL METABOLISM OF DIETARY TRYPTOPHAN ENHANCES ARYL HYDROCARBON RECEPTOR ACTIVATION: IMPLICATIONS FOR IBD

Rondeau, L. E., Clarizio, A. V., Jury, J., Gibson, D. L., Bercik, P., Sokol, H., & Fernández, A. C. (2020) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwz047.041 · Cited by 3

The relationship between tryptophan metabolism and gut microbiota: Interaction mechanism and potential effects in infection treatment

Pei, T., Li, W., Zhou, Z., Zhang, Q., Yu, G., Yin, S., Chen, H., & Tang, J. (2025) · Microbiological Research · doi:10.1016/j.micres.2025.128211 · Cited by 40

Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity

Dong, F., Hao, F., Murray, I. A., Smith, P. B. W., Koo, I., Tindall, A. M., Kris‐Etherton, P. M., Gowda, K., Amin, S., Patterson, A. D., et al. (2020) · Gut Microbes · doi:10.1080/19490976.2020.1788899 · Cited by 252