Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase-Mediated Antiviral Response

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The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity

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Integrative proteomics reveals an increase in non-degradative ubiquitylation in activated CD4+ T cells

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Insights into Ebola Virus VP35 and VP24 Interferon Inhibitory Functions and their Initial Exploitation as Drug Targets

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VAMP8 Contributes to the TRIM6-Mediated Type I Interferon Antiviral Response during West Nile Virus Infection

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TRIMming Type I Interferon-Mediated Innate Immune Response in Antiviral and Antitumor Defense

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Unanchored Ubiquitin Chains, Revisited

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Fish TRIM16L exerts negative regulation on antiviral immune response against grouper iridoviruses

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HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3

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K48-linked polyubiquitination of dengue virus NS1 protein inhibits its interaction with the viral partner NS4B

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Regulation of cGAS/STING signaling and corresponding immune escape strategies of viruses

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E3-ubiquitin ligase TRIM6 aggravates myocardial ischemia/reperfusion injury via promoting STAT1-dependent cardiomyocyte apoptosis

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TRIM6 Reduces Ferroptosis and Chemosensitivity by Targeting SLC1A5 in Lung Cancer

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Clinical potential of oligonucleotide-based therapeutics in the respiratory system

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Immune and non-immune responses to hepatitis C virus infection

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Global functional profiling of human ubiquitome identifies E3 ubiquitin ligase DCST1 as a novel negative regulator of Type-I interferon signaling

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Tripartite motif-containing protein 6 facilitates growth and migration of breast cancer through degradation of STUB1

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Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly

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Disease classification via gene network integrating modules and pathways

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Unconventional posttranslational modification in innate immunity

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Modulation of virus-induced neuroinflammation by the autophagy receptor SHISA9 in mice

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Type I and Type II Interferon Antagonism Strategies Used by Paramyxoviridae: Previous and New Discoveries, in Comparison

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TRIM6 ablation reverses ICB resistance in MSS gastric cancer by unleashing cGAS-STING-dependent antitumor immunity

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Tripartite Motif Protein 6 Promotes Colorectal Cancer Cell Migration and Metastasis via SOCS2-STAT3 Signaling

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Surveillance for Intracellular Antibody by Cytosolic Fc Receptor TRIM21

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Dictyostelium as model for studying ubiquitination and deubiquitination

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Roles of IκB kinase ε in the innate immune defense and beyond

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TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication

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Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication

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Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling

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Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation

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The E3 ubiquitin ligase MID1/TRIM18 promotes atypical ubiquitination of the BRCA2-associated factor 35, BRAF35

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SERPINB1 promotes Senecavirus A replication by degrading IKBKE and regulating the IFN pathway via autophagy

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TRIM6 facilitates SARS‐CoV‐2 proliferation by catalyzing the K29‐typed ubiquitination of NP to enhance the ability to bind viral genomes

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E2 conjugating enzymes: A silent but crucial player in ubiquitin biology

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IKKε isoform switching governs the immune response against EV71 infection

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DLG1 promotes the antiviral innate immune response by inhibiting p62-mediated autophagic degradation of IKKε

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Regulation of Tripartite Motif-Containing Proteins on Immune Response and Viral Evasion

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Analysis of Global Transcriptome Change in Mouse Embryonic Fibroblasts After dsDNA and dsRNA Viral Mimic Stimulation

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TRIM47 promotes HDM‐induced bronchial epithelial pyroptosis by regulating NEMO ubiquitination to activate NF‐κB/NLRP3 signaling

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Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases

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Exploration of drug repurposing for Mpox outbreaks targeting gene signatures and host-pathogen interactions

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UbcD4, an ortholog of E2-25K/Ube2K, is essential for activation of the immune deficiency pathway in Drosophila

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Unanchored Lysine48-linked polyubiquitin chains positively regulate the type I IFN-mediated antiviral response (P1391)

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A novel role for TRIM6 and unanchored ubiquitin in inflammatory disease during virus infection via the PI3K-AKT signaling pathway

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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

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Unanchored Polyubiquitin Chains and Innate Immune Sensing of Influenza Virus Infection

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