Vernonia cinerea leaves as the source of phenolic compounds, antioxidants, and anti-diabetic activity using microwave-assisted extraction technique
Abstract
Diabetes mellitus is a metabolic disorder disease emanating from the inability of body’s response to high glucose levels in the blood. However, the side-effects from consuming synthetic drugs have reduced the effectiveness, thus, the potential of purple fleabane (Vernonia cinerea) leaf was investigated using microwave-assisted extraction (MAE) in this study. The influences of extraction factors such as irradiation time, microwave power level, feed/solvent, and ethanol concentration on the recovery yields of polyphenol and flavonoids were as well studied. Thirty experimental runs using a face-centered central composite design (FCCCD) with six centre points were employed and optimal yields were obtained by generating quadratic models based on response surface methodology. The obtained optimal MAE conditions were as follows: irradiation time, 2 min; microwave power level, 444 W; feed/solvent, 1:14 g/mL; and ethanol concentration, 47% v/v. There was an insignificant difference between the predicted and experimental data (p > 0.05), showing good predictive models for the extraction of phenolic compounds from V. cinerea leaves using MAE. Also, the results confirmed that MAE can recover higher phenolic compounds, antioxidant, and anti-diabetic activities from V. cinerea leaves in shorter extraction time. In addition, the phenolic compounds in V. cinerea leaf extract were identified using liquid chromatography-mass spectrometry quadrupole time of flight (LC–MS-Q-TOF) and Fourier tran…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Longer irradiation time generally increases the extraction of essential oil and/or secondary metabolite and thus increases yield.
“It is expected that the longer the irradiation time, the higher the extraction of the essential oil and/or secondary metabolite and thus the higher the yield”
From Optimized microwave-assisted azadirachtin extraction using response surface methodology (2024) · cites this paper as [45]
In some situations, prolonged extraction times may decrease yield.
“however, in some situations, the yield may decrease when having prolonged extraction times [45].”
From Optimized microwave-assisted azadirachtin extraction using response surface methodology (2024) · cites this paper as [45]
Cites
Thaipong, K., Boonprakob, U., Crosby, K. M., Cisneros‐Zevallos, L., & Byrne, D. (2006) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2006.01.003 · Cited by 3,649 · see citing works
Khuri, A. I., & Mukhopadhyay, S. (2010) · Wiley Interdisciplinary Reviews Computational Statistics · doi:10.1002/wics.73 · Cited by 2,137 · see citing works
Review on in vivo and in vitro methods evaluation of antioxidant activity
Alam, M. N., Bristi, N. J., & Rafiquzzaman, M. (2012) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2012.05.002 · Cited by 1,769 · see citing works
Adesegun, S., Ayoola, G. A., Coker, H., Adepoju-Bello, A. A., Obaweya, K., Ezennia, E., & Atangbayila, T. (2008) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v7i3.14686 · Cited by 851 · see citing works
Tundis, R., Loizzo, M. R., & Menichini, F. (2010) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955710791331007 · Cited by 851 · see citing works
Optimization of extraction of phenolic compounds from wheat using response surface methodology
LIYANAPATHIRANA, C., & SHAHIDI, F. (2005) · Food Chemistry · doi:10.1016/j.foodchem.2004.08.050 · Cited by 809 · see citing works
Microwave-assisted extractions of active ingredients from plants
Chan, C.-H., Yusoff, R., Ngoh, G.-C., & Kung, F. W.-L. (2011) · Journal of Chromatography A · doi:10.1016/j.chroma.2011.07.040 · Cited by 687 · see citing works
Optimization of microwave-assisted extraction of polyphenols from Myrtus communis L. leaves
Dahmoune, F., Nayak, B., Moussi, K., Remini, H., & Madani, K. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2014.06.066 · Cited by 539 · see citing works
Oliveira, R. N., Mancini, M. C., de Oliveira, F. C. S., Passos, T. M., Quilty, B., Thiré, R. M. D. S. M., & McGuinness, G. B. (2016) · Matéria (Rio de Janeiro) · doi:10.1590/s1517-707620160003.0072 · Cited by 489 · see citing works
α-Glucosidase inhibitors isolated from medicinal plants
Yin, Z., Zhang, W., Feng, F., Zhang, Y., & Kang, W. (2014) · Food Science and Human Wellness · doi:10.1016/j.fshw.2014.11.003 · Cited by 397 · see citing works
In-vitro alpha amylase inhibitory activity of the leaf extracts of Adenanthera pavonina
Wickramaratne, M. N., Punchihewa, J. C., & Wickramaratne, D. B. M. (2016) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-016-1452-y · Cited by 341 · see citing works
PRIMARY PREVENTION OF DIABETES: What Can Be Done and How Much Can Be Prevented?
Schulze, M. B., & Hu, F. B. (2004) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.26.021304.144532 · Cited by 330 · see citing works
Microwave-assisted extraction of tea phenols: A phenomenological study
Spigno, G., & Faveri, D. M. D. (2009) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2009.01.006 · Cited by 322 · see citing works
Modes of Inhibition of α -Amylase and α -Glucosidase by Aqueous Extract of Morinda lucida Benth Leaf
Kazeem, M. I., Adamson, J. O., & Ogunwande, I. A. (2013) · BioMed Research International · doi:10.1155/2013/527570 · Cited by 320 · see citing works
Hayat, K., Hussain, S., Abbas, S., Farooq, U., Ding, B., Xia, S., Jia, C., Zhang, X., & Xia, W. (2009) · Separation and Purification Technology · doi:10.1016/j.seppur.2009.08.012 · Cited by 288 · see citing works
Dahmoune, F., Spigno, G., Moussi, K., Remini, H., Cherbal, A., & Madani, K. (2014) · Industrial Crops and Products · doi:10.1016/j.indcrop.2014.06.035 · Cited by 285 · see citing works
Optimization of ethanol–water extraction of lignans from flaxseed
Zhang, Z. S., Li, D., Wang, L.-J., Özkan, N., Chen, X. D., Mao, Z. H., & Yang, H.-Z. (2007) · Separation and Purification Technology · doi:10.1016/j.seppur.2007.03.006 · Cited by 248 · see citing works
Optimization of microwave-assisted extraction of polyphenols from Quercus bark
Bouras, M., Chadni, M., Barba, F. J., Grimi, N., Bals, O., & Vorobiev, E. (2015) · Industrial Crops and Products · doi:10.1016/j.indcrop.2015.09.018 · Cited by 215 · see citing works
Márquez, D. B. M., Martínez-Ávila, G. C. G., Wong‐Paz, J. E., Belmares, R. E., Rodrı́guez-Herrera, R., & Aguilar, C. N. (2013) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2013.02.008 · Cited by 209 · see citing works
Alara, O. R., Nour, A. H., & Olalere, O. A. (2017) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2017.10.007 · Cited by 184 · see citing works
Self-citationRamaswamy, M. (2014) · Cited by 176 · see citing works
van den Worm, E., Beukelman, C. J., van den Berg, A. J. J., Kroes, B. H., Labadie, R. P., & van Dijk, H. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01516-3 · Cited by 170 · see citing works
Alara, O. R., Abdurahman, N. H., & Olalere, O. A. (2017) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2017.08.001 · Cited by 155 · see citing works
Self-citationKarabegović, I., Stojičević, S. S., Veličković, D. T., Todorović, Z. B., Nikolić, N., & Lazić, M. (2014) · Industrial Crops and Products · doi:10.1016/j.indcrop.2013.12.047 · Cited by 153 · see citing works
Saravanan, S., & Thangaraj, P. (2014) · Food Science and Human Wellness · doi:10.1016/j.fshw.2014.05.001 · Cited by 150 · see citing works
Bhuyan, D. J., Vuong, Q. V., Chalmers, A., van Altena, I. A., Bowyer, M. C., & Scarlett, C. J. (2015) · Industrial Crops and Products · doi:10.1016/j.indcrop.2015.02.044 · Cited by 137 · see citing works
Chen, J., Mangelinckx, S., Ma, L., Wang, Z., Li, W., & KIMPE, N. D. (2014) · Fitoterapia · doi:10.1016/j.fitote.2014.08.015 · Cited by 125 · see citing works
Hydrogen Peroxide Radical Scavenging and Total Antioxidant Activity of Hawthorn
Keser, S., Çeli̇k, S., Türkoğlu, S., Yılmaz, Ö., & Türkoğlu, İ. (2012) · Cited by 104 · see citing works
Uddin, N., Hasan, M. R., Hossain, M. M., Sarker, A., Hasan, A. H. M. N., Islam, A. F. M. M., Chowdhury, M. M. H., & Rana, M. S. (2014) · Asian Pacific Journal of Tropical Biomedicine · doi:10.12980/apjtb.4.2014c1173 · Cited by 96 · see citing works
Trans-, cis-, and dihydro-resveratrol: a comparative study
Anisimova, N. Y., Kiselevsky, M. V., Sosnov, A. V., Sadovnikov, S. V., Stankov, I. N., & Gakh, A. A. (2011) · Chemistry Central Journal · doi:10.1186/1752-153x-5-88 · Cited by 85 · see citing works
Shah, S. R., Ukaegbu, C. I., Hamid, H. A., & Alara, O. R. (2018) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-018-9810-8 · Cited by 81 · see citing works
Self-citationThe neuroprotective effects of apocynin
Simonyi, Á. (2012) · Frontiers in Bioscience-Elite · doi:10.2741/e535 · Cited by 71 · see citing works
The neuroprotective effects of apocynin
Simonyi, Á. (2011) · Frontiers in Bioscience-Elite · doi:10.2741/535 · Cited by 62 · see citing works
1,2,3,4,6-penta-O-galloyl-β-d-glucose: A cholinesterase inhibitor from Terminalia chebula
Sancheti, S., Sancheti, S., Um, B., & Seo, S. (2009) · South African Journal of Botany · doi:10.1016/j.sajb.2009.11.006 · Cited by 62 · see citing works
Wang, Q., Li, H., Sun, Z., Dong, L., Gao, L., Liu, C., & Wang, X. (2016) · Scientific Reports · doi:10.1038/srep36543 · Cited by 62 · see citing works
Bioactive sesquiterpene lactones and other compounds isolated from Vernonia cinerea
Youn, U. J., Miklóssy, G., Chai, X., Wongwiwatthananukit, S., Toyama, O., Songsak, T., Turkson, J., & Chang, L. C. (2013) · Fitoterapia · doi:10.1016/j.fitote.2013.12.013 · Cited by 59 · see citing works
A novel management of diabetes by means of strong antioxidants’ combination
Tabatabaei‐Malazy, O., Larijani, B. A., & Abdollahi, M. R. (2013) · Journal of Medical Hypotheses and Ideas · doi:10.1016/j.jmhi.2012.12.002 · Cited by 56 · see citing works
Balan, K., Ratha, P., Prakash, G., Viswanathamurthi, P., Adisakwattana, S., & Palvannan, T. (2014) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2014.07.002 · Cited by 54 · see citing works
Review on diabetes, synthetic drugs and glycemic effects of medicinal plants
Mohammed, S. A., Yaqub, A., Nicholas, A. O., Arastus, W., Muhammad, M., & Abdullahi, S. A. (2013) · Journal of Medicinal Plants Research · doi:10.5897/jmpr2013.5169 · Cited by 42 · see citing works
Alara, O. R., Mudalip, S. K. A., & Olalere, O. A. (2017) · Journal of Applied Research on Medicinal and Aromatic Plants · doi:10.1016/j.jarmap.2017.02.002 · Cited by 40 · see citing works
Self-citationDeo, S., Janghel, A., Raut, P., Bhosle, D., Verma, C. K., Kumar, S. S., Agrawal, M., Amit, N., Sharma, M. K., Giri, T. K., et al. (2015) · Research Journal of Pharmacy and Technology · doi:10.5958/0974-360x.2015.00104.3 · Cited by 38 · see citing works
Bouterfas, K., Mehdadi, Z., Benmansour, D., Khaled, M. B., Bouterfas, M., & Latrèche, A. (2014) · International Journal of Organic Chemistry · doi:10.4236/ijoc.2014.45032 · Cited by 33 · see citing works
Prasopthum, A., Pouyfung, P., Sarapusit, S., Srisook, E., & Rongnoparut, P. (2015) · Drug Metabolism and Pharmacokinetics · doi:10.1016/j.dmpk.2014.12.005 · Cited by 32 · see citing works
Toxicity study ofVernonia cinerea
Latha, L. Y., Darah, I., Jain, K. K., & Sasidharan, S. (2009) · Pharmaceutical Biology · doi:10.3109/13880200903046203 · Cited by 32 · see citing works
Ramachandran, S., Rajasekaran, A., & Adhirajan, N. (2013) · ISRN Pharmacology · doi:10.1155/2013/484675 · Cited by 29 · see citing works
Semwal, D. K., Rawat, U., Semwal, R., Singh, R., Krishan, P., Singh, M., & Singh, G. J. P. (2009) · Journal of Asian Natural Products Research · doi:10.1080/10286020903352526 · Cited by 28 · see citing works
Ketsuwan, N., Leelarungrayub, J., Kothan, S., & Singhatong, S. (2017) · Drug Design Development and Therapy · doi:10.2147/dddt.s126882 · Cited by 24 · see citing works
Effects of Vernonia cinerea on reproductive performance in streptozotocin-induced diabetic rats
POMJUNYA, A., RATTHANOPHART, J., & Fungfuang, W. (2017) · Journal of Veterinary Medical Science · doi:10.1292/jvms.16-0466 · Cited by 23 · see citing works
Peng, F., Cheng, C., Xie, Y., & Yang, Y. (2015) · Food Science and Technology Research · doi:10.3136/fstr.21.463 · Cited by 21 · see citing works
PHARMACOGNOSTICAL AND PHYTOCHEMICAL STUDIES OF THE PLANT SAHADEVI [VERNONIA CINEREA (L.) LESS.]
Giby, A. (2015) · International Journal of Research in Ayurveda and Pharmacy · doi:10.7897/2277-4343.06112 · Cited by 9 · see citing works
Flagged first, then by citations
2 of the 52 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Extraction of phenolic compounds: A review
Alara, O. R., Abdurahman, N. H., & Ukaegbu, C. I. (2021) · Current Research in Food Science · doi:10.1016/j.crfs.2021.03.011 · Cited by 1,209 · see citing works
Self-citationOsorio-Tobón, J. F. (2020) · Journal of Food Science and Technology · doi:10.1007/s13197-020-04433-2 · Cited by 407 · see citing works
Soxhlet extraction of phenolic compounds from Vernonia cinerea leaves and its antioxidant activity
Alara, O. R., Nour, A. H., & Ukaegbu, C. I. (2018) · Journal of Applied Research on Medicinal and Aromatic Plants · doi:10.1016/j.jarmap.2018.07.003 · Cited by 222 · see citing works
Self-citationGao, M.-Z., Cui, Q., Wang, L.-T., Meng, Y., Yu, L., Li, Y.-Y., & Fu, Y.-J. (2020) · Microchemical Journal · doi:10.1016/j.microc.2020.104598 · Cited by 171 · see citing works
Green and Sustainable Valorization of Bioactive Phenolic Compounds from Pinus By-Products
Ferreira‐Santos, P., Zanuso, E., Genisheva, Z. A., Rocha, C. M. R., & Teixeira, J. A. (2020) · Molecules · doi:10.3390/molecules25122931 · Cited by 160 · see citing works
Akbari, S., Nour, A. H., Yunus, R. M., Alara, O. R., & Abayomi, O. O. (2018) · Materials Science for Energy Technologies · doi:10.1016/j.mset.2018.12.001 · Cited by 150 · see citing works
Self-citationAlara, O. R., Nour, A. H., Ukaegbu, C. I., & Kabbashi, N. A. (2019) · Journal of Taibah University for Science · doi:10.1080/16583655.2019.1582460 · Cited by 127 · see citing works
Self-citationDeep eutectic solvents for the extraction of polyphenols from food plants
Aktaş, H., & Kurek, M. A. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.138629 · Cited by 132 · see citing works
Garrido, T., Gizdavic‐Nikolaidis, M. R., Leceta, I., Urdanpilleta, M., Guerrero, P., de la Caba, K., & Kilmartin, P. A. (2019) · Waste Management · doi:10.1016/j.wasman.2019.03.031 · Cited by 114 · see citing works
Fu, X., Belwal, T., He, Y., Xu, Y., Li, L., & Luo, Z. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.131042 · Cited by 109 · see citing works
Wang, Z., Wang, Z., Huang, W., 索吉明, Chen, X., Ding, K., Sun, Q., & Zhang, H. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.12.213 · Cited by 103 · see citing works
Alara, O. R., & Abdurahman, N. H. (2019) · Industrial Crops and Products · doi:10.1016/j.indcrop.2019.05.053 · Cited by 101 · see citing works
Self-citationNáthia-Neves, G., & Alonso, E. (2020) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2020.10.008 · Cited by 101 · see citing works
Doulabi, M., Golmakani, M., & Ansari, S. (2020) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.14853 · Cited by 89 · see citing works
Abeysinghe, T., Kumara, K. A. H., Kaushalya, K. A. D., Chandrika, U. G., & Alwis, D. D. D. H. (2021) · Heliyon · doi:10.1016/j.heliyon.2021.e07449 · Cited by 89 · see citing works
Wu, L., Chen, Z., Li, S., Wang, L., & Zhang, J. (2021) · Separation and Purification Technology · doi:10.1016/j.seppur.2021.118339 · Cited by 87 · see citing works
Qin, G., Zhang, F., Ren, M., Chen, X., Liu, C., Li, G., Gao, Q., Qiao, L., Jiang, Y., Zhu, L., et al. (2023) · Food Chemistry · doi:10.1016/j.foodchem.2023.136828 · Cited by 73 · see citing works
Wang, R., He, R., Li, Z., Li, S., Li, C., & Wang, L. (2021) · Separation and Purification Technology · doi:10.1016/j.seppur.2021.119159 · Cited by 72 · see citing works
Panigrahy, N., Barik, M. R., Sahoo, R. K., & Sahoo, N. K. (2019) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2019.104837 · Cited by 68 · see citing works
Vázquez-González, Y., Ragazzo‐Sánchez, J. A., & Calderón‐Santoyo, M. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.127211 · Cited by 67 · see citing works
Alara, O. R., Nour, A. H., Ali, H. A., & Zain, N. M. (2021) · Future Foods · doi:10.1016/j.fufo.2021.100035 · Cited by 67 · see citing works
Self-citationKashyap, P., Riar, C. S., & Jindal, N. (2020) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-020-00611-0 · Cited by 66 · see citing works
Andrade, C., Gomes, N. G. M., Duangsrisai, S., Andrade, P. B., Pereira, D. M., & Valentão, P. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.113177 · Cited by 68 · see citing works
Alara, O. R., & Abdurahman, N. H. (2018) · Journal of Food Science and Technology · doi:10.1007/s13197-018-3512-4 · Cited by 62 · see citing works
Self-citationMartinović, M., Krgović, N., Nešić, I., Žugić, A., & Tadić, V. (2022) · Antioxidants · doi:10.3390/antiox11112295 · Cited by 65 · see citing works
Extraction Techniques of Phenolic Compounds from Plants
Jahromi, S. G. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.84705 · Cited by 61 · see citing works
Garofulić, I. E., Malin, V., Repajić, M., Zorić, Z., Pedišić, S., Sterniša, M., Možina, S. S., & Dragović‐Uzelac, V. (2021) · Molecules · doi:10.3390/molecules26206153 · Cited by 58 · see citing works
Recent Advancements in Microwave-Assisted Extraction of Flavonoids: A Review
Wang, N., Zhu, H., Wang, M., Zhao, S., Sun, G., & Li, Z. (2024) · Food and Bioprocess Technology · doi:10.1007/s11947-024-03574-y · Cited by 57 · see citing works
Akbari, S., Nour, A. H., & Yunus, R. M. (2019) · Comptes Rendus Chimie · doi:10.1016/j.crci.2019.07.007 · Cited by 57 · see citing works
Chen, Q., Dong, W., Wei, C., Hu, R., & Long, Y. (2020) · Industrial Crops and Products · doi:10.1016/j.indcrop.2020.112405 · Cited by 57 · see citing works
Sonar, M. P., & Rathod, V. K. (2020) · Chemical Data Collections · doi:10.1016/j.cdc.2020.100545 · Cited by 55 · see citing works
Recovery of Chlorogenic Acids from Agri-Food Wastes: Updates on Green Extraction Techniques
Frosi, I., Montagna, I., Colombo, R., Milanese, C., & Papetti, A. (2021) · Molecules · doi:10.3390/molecules26154515 · Cited by 52 · see citing works
Phenolic compounds in mango fruit: a review
Tacias-Pascacio, V. G., Castañeda‐Valbuena, D., Fernández‐Lafuente, R., Berenguer‐Murcia, Á., Meza‐Gordillo, R., Gutiérrez, L., Pacheco, N., Cuevas-Bernardino, J. C., & Ayora‐Talavera, T. (2021) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-021-01192-2 · Cited by 52 · see citing works
Microwave-Assisted Extraction of Bioactive Compounds (Review)
Nour, A. H., Alara, O. R., Nour, A. H., Omer, M. S., & Noormazlinah, A. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.96092 · Cited by 50 · see citing works
Self-citationSolaberrieta, I., Jiménez, A., & Garrigós, M. C. (2022) · Antioxidants · doi:10.3390/antiox11061058 · Cited by 50 · see citing works
Kaur, P., Kumar Pandey, D., Gupta, R. C., & Dey, A. (2019) · Industrial Crops and Products · doi:10.1016/j.indcrop.2019.02.055 · Cited by 48 · see citing works
Singh, J., Rasane, P., Kaur, R., Kaur, H., Garg, R., Kaur, S., Erċışlı, S., Choudhary, R., Škrovánková, S., & Mlček, J. (2023) · Frontiers in Chemistry · doi:10.3389/fchem.2023.1290619 · Cited by 54 · see citing works
Cacique, A. P., Barbosa, É. S., de Pinho, G. P., & Silvério, F. O. (2020) · Ciência e Agrotecnologia · doi:10.1590/1413-7054202044017420 · Cited by 54 · see citing works
da Rosa, R. G., Sganzerla, W. G., Barroso, T. L. C. T., Buller, L. S., Berni, M. D., & Forster‐Carneiro, T. (2022) · Sustainable Chemistry and Pharmacy · doi:10.1016/j.scp.2022.100656 · Cited by 46 · see citing works
Wasilewski, T., Hordyjewicz-Baran, Z., Zarębska, M., Stanek, N., Zajszły-Turko, E., Tomaka, M., Bujak, T., & Nizioł-Łukaszewska, Z. (2022) · Molecules · doi:10.3390/molecules27082444 · Cited by 43 · see citing works
Mendes, M. K. D. A., Oliveira, C. B. D. S., Veras, M. D. A., Araujo, B. Q., Dantas, C., Chaves, M. H., Júnior, C. A. L., & Vieira, E. C. (2019) · Talanta · doi:10.1016/j.talanta.2019.06.100 · Cited by 41 · see citing works
Mostofa, M. G., Reza, A. S. M. A., Khan, Z., Munira, M. S., Khatoon, M. M., Kabir, S. R., Sadik, G., Ağagündüz, D., Capasso, R., Kazi, M., et al. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e23400 · Cited by 40 · see citing works
Extraction as a Critical Step in Phytochemical Analysis
Mosić, M. D., Dramićanin, A., Ristivojević, P. M., & Milojković‐Opsenica, D. (2019) · Journal of AOAC International · doi:10.5740/jaoacint.19-0251 · Cited by 46 · see citing works
Benmoussa, H., Béchohra, I., He, S., Elfalleh, W., & Chawech, R. (2022) · Industrial Crops and Products · doi:10.1016/j.indcrop.2022.115995 · Cited by 40 · see citing works
Alara, O. R., & Nour, A. H. (2019) · Chemical Data Collections · doi:10.1016/j.cdc.2019.100200 · Cited by 39 · see citing works
Self-citationSarangi, P. K., Srivastava, R. K., Singh, A. K., Sahoo, U. K., Prus, P., & Dziekański, P. (2023) · Sustainability · doi:10.3390/su151612520 · Cited by 38 · see citing works
From Olive Oil Production to By-Products: Emergent Technologies to Extract Bioactive Compounds
Soares, T. F., Alves, R. C., & Oliveira, M. B. P. P. (2024) · Food Reviews International · doi:10.1080/87559129.2024.2354331 · Cited by 37 · see citing works
Gupta, R., Singh, A., Nema, P. K., Roy, T., Kumar, S., & Kumar, A. P. (2024) · ACS Omega · doi:10.1021/acsomega.4c04468 · Cited by 35 · see citing works
Das, B., Lou-Franco, J., Gilbride, B., Ellis, M. G., Stewart, L. D., Grant, I. R., Balasubramanian, P., & Cao, C. (2022) · ACS Applied Bio Materials · doi:10.1021/acsabm.2c00180 · Cited by 35 · see citing works
Akbari, S., Nour, A. H., Yunus, R. M., Alsaggaf, A. H. A., & Noormazlinah, A. (2021) · South African Journal of Botany · doi:10.1016/j.sajb.2021.02.027 · Cited by 33 · see citing works
Alara, O. R., Mudalip, S. K. A., Nour, A. H., Mahmoud, M. S., & Obanijesu, E. O. (2019) · Chemical Data Collections · doi:10.1016/j.cdc.2019.100277 · Cited by 33 · see citing works
Self-citationSantana, Á. L., & Macêdo, G. A. (2019) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2019.07.019 · Cited by 31 · see citing works
Alves, T. P., Triques, C. C., Palsikowski, P. A., da Silva, C., Fiorese, M. L., da Silva, E. A., & Fagundes‐Klen, M. R. (2021) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2021.105468 · Cited by 30 · see citing works
Bao, N., Wang, D., Fu, X., Xie, H., Gao, G., & Luo, Z. (2021) · Foods · doi:10.3390/foods10020239 · Cited by 27 · see citing works
Luetragoon, T., Sranujit, R. P., Noysang, C., Thongsri, Y., Potup, P., Somboonjun, J., Maichandi, N., Suphrom, N., Sangouam, S., & Usuwanthim, K. (2021) · Plants · doi:10.3390/plants10071336 · Cited by 27 · see citing works
Etxabide, A., Garrido, T., Uranga, J., Guerrero, P., & de la Caba, K. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.09.030 · Cited by 27 · see citing works
Alara, O. R., Nour, A. H., & Mudalip, S. K. A. (2019) · Chemical Engineering & Technology · doi:10.1002/ceat.201800462 · Cited by 26 · see citing works
Self-citationAlara, O. R., Nour, A. H., Obanijesu, E. O., Alara, J. A., & Mudalip, S. K. A. (2019) · Journal of Food Process Engineering · doi:10.1111/jfpe.13339 · Cited by 26 · see citing works
Self-citationGonzaga, L. J., Roa, M. E. P., Lavecchia, R., & Zuorro, A. (2025) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2025.116858 · Cited by 27 · see citing works
Kuhn, F., de Azevedo, E. S., & Noreña, C. P. Z. (2020) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.14834 · Cited by 24 · see citing works
Bhutani, M., Gaur, S. S., Shams, R., Dash, K. K., Shaikh, A. M., & Kovács, B. (2025) · Future Foods · doi:10.1016/j.fufo.2025.100710 · Cited by 23 · see citing works
Alara, O. R., Nour, A. H., Ukaegbu, C. I., Azhari, N. H., & Kabbashi, N. A. (2018) · Journal of Liquid Chromatography & Related Technologies · doi:10.1080/10826076.2018.1511995 · Cited by 23 · see citing works
Self-citationXue, H., Tan, J., Fan, L., Li, Q., & Cai, X. D. (2021) · Journal of Food Process Engineering · doi:10.1111/jfpe.13688 · Cited by 23 · see citing works
Study on the inhibition mechanism of eucalyptus tannins against Microcystis aeruginosa
Xie, L., Ma, Z., Yang, G., Huang, Y., Wen, T., Deng, Y., Sun, J., Zheng, S., Wu, F., Huang, K., et al. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.114452 · Cited by 21 · see citing works
Oke, E. O., Adeyi, O., Okolo, B. I., Adeyi, J. A., Ude, C. J., Okhale, S., Nnabodo, D., Okolie, J. A., Adeyanju, J. A., Ajala, O. O., et al. (2023) · Cleaner Engineering and Technology · doi:10.1016/j.clet.2023.100624 · Cited by 21 · see citing works
Alara, O. R., Nour, A. H., Ukaegbu, C. I., Hassan, Z., & Kabbashi, N. A. (2018) · Data in Brief · doi:10.1016/j.dib.2018.10.159 · Cited by 21 · see citing works
Self-citationRecent Advances in Extraction of Polyphenols by Advanced Extraction Methods
Yendurı, S., Venkatesh, K. V., & Prashant, K. N. (2025) · Phytochemical Analysis · doi:10.1002/pca.70012 · Cited by 20 · see citing works
Monton, C., Keawchay, P., Pokkrong, C., Kamnoedthapaya, P., Navabhatra, A., Suksaeree, J., Wunnakup, T., Chankana, N., & Songsak, T. (2023) · Scientia Pharmaceutica · doi:10.3390/scipharm91020017 · Cited by 18 · see citing works
Akbari, S., Nour, A. H., & Yunus, R. M. (2020) · IOP Conference Series Materials Science and Engineering · doi:10.1088/1757-899x/736/2/022024 · Cited by 18 · see citing works
Ganorkar, P. V., Jadeja, G. C., & Desai, M. A. (2022) · Journal of Environmental Management · doi:10.1016/j.jenvman.2021.114419 · Cited by 18 · see citing works
Boukerche, H., Malki, F., Saidji, N., Ghaliaoui, N., Bensalem, A., & Mokrane, H. (2023) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-023-04029-8 · Cited by 17 · see citing works
Mastellone, G., Pacheco‐Fernández, I., Rubiolo, P., Pino, V., & Cagliero, C. (2020) · Molecules · doi:10.3390/molecules25133072 · Cited by 17 · see citing works
Frosi, I., Balduzzi, A., Colombo, R., Milanese, C., & Papetti, A. (2023) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2023.11.009 · Cited by 16 · see citing works
Ly, L., & Sothornvit, R. (2024) · Food and Bioprocess Technology · doi:10.1007/s11947-024-03393-1 · Cited by 16 · see citing works
Liu, Y., Dar, B. N., Makroo, H. A., Aslam, R., Martí-Quijal, F. J., Castagnini, J. M., Amigo, J. M., & Barba, F. J. (2024) · Antioxidants · doi:10.3390/antiox13121510 · Cited by 16 · see citing works
Lin, S., Li, H., Wang, Z., Liu, X., Yang, Y., Cao, Z.-W., Du, G., Zhao, L., Zhang, Q. R., Wu, D., et al. (2019) · Antioxidants · doi:10.3390/antiox8080266 · Cited by 16 · see citing works
Yadav, R., Mohapatra, D., Subeesh, A., Shabeer, T. A., & Giri, S. K. (2023) · Process Biochemistry · doi:10.1016/j.procbio.2023.09.021 · Cited by 15 · see citing works
Zhang, Q., Peng, Y., Li, F., Xu, Y., Zhang, Q. R., Wu, D., Chen, M., Lin, S., & Qin, W. (2024) · eFood · doi:10.1002/efd2.154 · Cited by 15 · see citing works
Alara, O. R., Abdurahman, N. H., & Ali, H. A. (2023) · Chemical Papers · doi:10.1007/s11696-023-02771-x · Cited by 15 · see citing works
Self-citationMokaizh, A. A. B., Nour, A. H., & Ukaegbu, C. I. (2024) · Results in Engineering · doi:10.1016/j.rineng.2024.102892 · Cited by 14 · see citing works
Self-citationHossain, M. S., Hasnat, S., Akter, S., Mim, M. M., Tahcin, A., Hoque, M., Sutradhar, D., Keya, M. A. A., Sium, N. R., Hossain, S., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1465827 · Cited by 15 · see citing works
Özcan, F. Ş., Dikmen, H., Özcan, N., Çetin, Ö., Çelik, M., & Trendafilova, A. B. (2023) · Food Science & Nutrition · doi:10.1002/fsn3.3775 · Cited by 13 · see citing works
Yang, Y., Wang, C.-S., & Wei, M. (2019) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2019.09.004 · Cited by 13 · see citing works
Makkiyah, F. A., Rahmi, E. P., Susantiningsih, T., Marliani, N., Arista, R. A., & Nurcholis, W. (2023) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2023.117043 · Cited by 13 · see citing works
Alara, O. R., Nour, A. H., & Mudalip, S. K. A. (2019) · Indonesian Journal of Chemistry · doi:10.22146/ijc.40863 · Cited by 13 · see citing works
Self-citationRouhou, M. C., Douiri, S., Abdelmoumen, S., Ghorbal, A., Lung, A., Raynaud, C., & Ghorbel, D. (2023) · Analytical Biochemistry · doi:10.1016/j.ab.2023.115139 · Cited by 12 · see citing works
Bao, N., Rashed, M. M. A., Jiang, B., Zhai, K., & Luo, Z. (2021) · ACS Omega · doi:10.1021/acsomega.1c04190 · Cited by 12 · see citing works
Nateghi, L., & Hosseini, E. (2023) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-023-01961-1 · Cited by 12 · see citing works
Ukaegbu, C. I., Shah, S. R., Hamid, H. A., Alara, O. R., & Sarker, M. Z. I. (2020) · Pharmaceutical Chemistry Journal · doi:10.1007/s11094-020-02174-2 · Cited by 12 · see citing works
Self-citationOke, E. O., Adeyi, O., Okolo, B. I., Adeyi, J. A., Nnabodo, D., Ude, C. J., Ajala, O. O., Okhale, S., Okolie, J. A., Otolorin, J. A., et al. (2023) · Cleaner Chemical Engineering · doi:10.1016/j.clce.2023.100097 · Cited by 11 · see citing works
Oufighou, A., Brahmi, F., Achat, S., Slimani, S., Arroul, Y., Kadi, A., Saadi, S., Guemghar-Haddadi, H., Madani, K., & Boulekbache-Makhlouf, L. (2024) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-024-02396-y · Cited by 11 · see citing works
Kaur, S., Panesar, P. S., & Chopra, H. K. (2022) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.16395 · Cited by 11 · see citing works
Kian-Pour, N., Ceyhan, T., Özmen, D., & Toker, Ö. S. (2024) · International Journal of Food Engineering · doi:10.1515/ijfe-2023-0237 · Cited by 11 · see citing works
Monton, C., Kittiratpattana, P., Nakyai, S., Sutapakul, T., Navabhatra, A., Wunnakup, T., Chankana, N., & Suksaeree, J. (2021) · Oriental Pharmacy and Experimental Medicine · doi:10.1007/s13596-021-00581-8 · Cited by 11 · see citing works
El‐Zeftawy, M., & Ghareeb, D. A. (2023) · Scientific Reports · doi:10.1038/s41598-023-39034-4 · Cited by 11 · see citing works
Theja, D. D., & Nirmala, S. (2023) · Intelligent Pharmacy · doi:10.1016/j.ipha.2023.11.005 · Cited by 10 · see citing works
Suksaeree, J., Navabhatra, A., Wunnakup, T., & Monton, C. (2022) · Trends in Sciences · doi:10.48048/tis.2022.3265 · Cited by 10 · see citing works
Harun, M. U., Palma, M., & Setyaningsih, W. (2025) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2025.101754 · Cited by 8 · see citing works
Ovatlarnporn, C., Basit, A., Paliwal, H., Nalinbenjapun, S., Sripetthong, S., Suksuwan, A., Mahamud, N., & Olatunji, O. J. (2024) · Phytochemical Analysis · doi:10.1002/pca.3395 · Cited by 8 · see citing works
- Authors
- Alara, O. R., Abdurahman, N. H., Ukaegbu, C. I., & Azhari, N. H.
- Affiliations
- Universiti Malaysia Pahang Al-Sultan Abdullah (MY)
- International University of Africa (SD)
- Venue
- Industrial Crops and Products
- Publisher
- Elsevier BV
- Published
- 2018-10
- Volume
- 122
- Pages
- 533-544
- ISSN
- 0926-6690 (ISSN-L)
- OpenAlex
- W2808345003
- Cited by
- 176
- References
- 52
- Citations by year
- 2026: 9 · 2025: 20 · 2024: 23 · 2023: 29 · 2022: 17 · 2021: 29 · 2020: 21 · 2019: 21 · 2018: 7
- FWCI
- 15.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Industrial Crops and Products (publishedVersion)
- UMP Institutional Repository (Universiti Malaysia Pahang) (acceptedVersion)
- Funders
- Universiti Malaysia Pahang (RDU180329)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- Vernonia cinerea, microwave-assisted extraction, phenolic compounds, flavonoids, antioxidant activity, antidiabetic activity, diabetes mellitus, α-amylase inhibition, α-glycosidase inhibition, extraction optimization, response surface methodology, functional foods
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review