The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Harnessing nanoparticles for immune modulation
Open accessAbstract
Recent approaches using nanoparticles engineered for immune regulation have yielded promising results in preclinical models of disease. The number of nanoparticle therapies is growing, fueled by innovations in nanotechnology and advances in understanding of the underlying pathogenesis of immune-mediated diseases. In particular, recent mechanistic insight into the ways in which nanoparticles interact with the mononuclear phagocyte system and impact its function during homeostasis and inflammation have highlighted the potential of nanoparticle-based therapies for controlling severe inflammation while concurrently restoring peripheral immune tolerance in autoimmune disease. Here we review recent advances in nanoparticle-based approaches aimed at immune-modulation, and discuss these in the context of concepts in polymeric nanoparticle development, including particle modification, delivery and the factors associated with successful clinical deployment.
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Cites
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The effect of particle design on cellular internalization pathways
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Self-citationGetts, D. R., Terry, R. L., Getts, M. T., Müller, M., Rana, S., Shrestha, B., Radford, J., Van Rooijen, N., Campbell, I. L., & King, N. J. C. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20080421 · Cited by 360
Self-citationGetts, D. R., Terry, R. L., Getts, M. T., Müller, M., Rana, S., Deffrasnes, C., Ashhurst, T. M., Radford, J., Hofer, M., Thomas, S., et al. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-246 · Cited by 95
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Niculescu, A.-G., Chircov, C., Bîrcă, A. C., & Grumezescu, A. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042011 · Cited by 678
Effects of engineered nanoparticles on the innate immune system
Liu, Y., Hardie, J., Zhang, X., & Rotello, V. M. (2017) · Seminars in Immunology · doi:10.1016/j.smim.2017.09.011 · Cited by 315
Nanoparticle-Based Vaccines Against Respiratory Viruses
Al-Halifa, S., Gauthier, L., Arpin, D., Bourgault, S., & Archambault, D. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00022 · Cited by 299
Nanoparticle–hydrogel superstructures for biomedical applications
Jiang, Y., Krishnan, N., Heo, J., Fang, R. H., & Zhang, L. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.05.041 · Cited by 266
Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation
Silva, A. L., Peres, C., Conniot, J., Matos, A. I., Moura, L., Carreira, B., Sainz, V., Scomparin, A., Satchi-Fainaro, R., Préat, V., et al. (2017) · Seminars in Immunology · doi:10.1016/j.smim.2017.09.003 · Cited by 95
Metadata
- Authors
- Getts, D. R., Shea, L. D., Miller, S. D., & King, N. J. C.
- Venue
- Trends in Immunology
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 36
- Issue
- 7
- Pages
- 419-427
- ISSN
- 1471-4906 (ISSN-L)
- OpenAlex
- W1649418318
- Cited by
- 233
- References
- 8
- FWCI
- 1.10
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Getts, D. R., Shea, L. D., Miller, S. D., & King, N. J. C. (2015). Harnessing nanoparticles for immune modulation. Trends in Immunology. https://doi.org/10.1016/j.it.2015.05.007
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
