Refractory ulcers: The role of tumor necrosis factor–α
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Elevation of TNFα leads to decreased production of granulation tissue, whereas low doses of TNFα promote collagen disposition.
“Elevation of TNFα leads to decreased production of granulation tissue, whereas low doses of TNFα promote collagen disposition,58–61 demonstrating the importance of accurate cytokine regulation during wound healing.”
From The Innate Immune System in Acute and Chronic Wounds (2016) · cites this paper as [61]
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- Authors
- Weinstein, D. A., & Kirsner, R. S.
- Affiliations
- University of Florida (US)
- University of Miami (US)
- Corresponding author
- Kirsner, Robert S.
- Venue
- Journal of the American Academy of Dermatology
- Publisher
- Elsevier BV
- Published
- 2010-07
- Volume
- 63
- Issue
- 1
- Pages
- 146-154
- ISSN
- 0190-9622 (ISSN-L)
- OpenAlex
- W2165900556
- Cited by
- 33
- References
- 132
- Citations by year
- 2024: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 3 · 2017: 1 · 2016: 5 · 2015: 6 · 2014: 1 · 2013: 4 · 2012: 6
- FWCI
- 0.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Academy of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Health Sciences › Medicine › Epidemiology › Autoimmune and Inflammatory Disorders
- Health Sciences › Medicine › Epidemiology › Nonmelanoma Skin Cancer Studies
- Keywords
- refractory ulcer, chronic wounds, TNF-α, wound healing, cytokines, growth factors, elastase activity, protease inhibitors
- MeSH terms
- Chronic Disease, Dermatitis, Humans, Inflammation, Leg Ulcer, Skin Ulcer, Tumor Necrosis Factor-alpha, Wound Healing
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