Cited by 165Cardiovascular Syncope and Autonomic DisordersBalance, Gait, and Falls PreventionHeart Rate Variability and Autonomic Control

Lower Limb and Abdominal Compression Bandages Prevent Progressive Orthostatic Hypotension in Elderly Persons

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Podoleanu, Cristian, Maggi, Roberto, Brignole, Michele, Croci, Francesco, Incze, Alexander, Solano, Alberto, Puggioni, Enrico, Carasca, Emilian·2006·Journal of the American College of Cardiology

Abstract

Objectives This study sought to assess the efficacy of compression bandage of legs and abdomen in preventing hypotension and symptoms.Background Progressive orthostatic hypotension can occur in elderly people during standing.Methods Twenty-one patients (70 +/- 11 years) affected by symptomatic progressive orthostatic hypotension underwent 2 tilt-test procedures, with and without elastic bandage of the legs (compression pressure 40 to 60 mm Hg) and of the abdomen (compression pressure 20 to 30 mm Hg) in a randomized crossover fashion. Leg bandage was administered for 10 min and was followed by an additional abdominal bandage for a further 10 min. Symptoms were evaluated by a 7-item Specific Symptom Score (SSS) questionnaire before and after 1 month of therapy with elastic compression stockings of the legs (prescribed in all patients irrespective of the results of the tilt study).Results In the control arm, systolic blood pressure decreased from 125 +/- 18 mm Hg immediately after tilting to 112 +/- 25 mm Hg after 10 min of sham leg bandage and to 106 +/- 25 mm Hg after 20 min despite the addition of sham abdominal bandage. The corresponding values with active therapy were 129 +/- 19 mm Hg, 127 +/- 17 mm Hg (p = 0.003 vs. control), and 127 +/- 21 mm Hg (p = 0.002 vs. control). In the active arm, 90% of patients remained asymptomatic, versus 53% in the control arm (p = 0.02). During the month before evaluation, the mean SSS score was 35.2 +/- 12.1 with dizziness, weakness, and palpitations accounting for 64% of the total score. The SSS score decreased to 22.5 +/- 11.3 after 1 month of therapy (p = 0.01).Conclusions Lower limb compression bandage is effective in avoiding orthostatic systolic blood pressure decrease and in reducing symptoms in elderly patients affected by progressive orthostatic hypotension.

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Crossref · 10.1016/j.jacc.2006.06.052

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  • Syncope due to OH is confirmed when syncope occurs while standing and there is concomitant significant OH.

    “Syncope due to OHis confirmed when syncope occurs while standing and there is concomitant significant OH. 18-24”

    From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [23]

    The paper describes blood pressure falling after a patient assumes an upright position and a patient becoming syncopal during testing (figure description; page unavailable). It also says progressive orthostatic hypotension is diagnosed by tilt testing (section labeled Results; page unavailable). It does not state the broader rule that syncope while standing with concomitant significant orthostatic hypotension confirms syncope due to OH. (LLM, conf=0.83)

    Experimental — accuracy not yet measured
  • Tilt testing may have value in distinguishing syncope from falls.

    “Tilt testing may have value in distinguishing syncope from falls. 23”

    From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [23]

    The Methods describe a diagnostic tilt test, and the Results state that tilt testing can diagnose progressive orthostatic hypotension in patients with syncope (page not provided). Our copy does not address using tilt testing to distinguish syncope from falls; searches for falls and that distinction found no such passage. (LLM, conf=0.82)

    Experimental — accuracy not yet measured

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1 of the 31 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

  1. Low PA, Gilden JL, Freeman R, et al. Efficacy of midrodrine vs. placebo in neurogenic orthostatic hypotension. JAMA 1997;13: 1046 -51.

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Authors
Podoleanu, C., Maggi, R., Brignole, M., Croci, F., Incze, A., Solano, A., Puggioni, E., & Carasca, E.
Affiliations
  • Spitalul Clinic Judetean de Urgenta Târgu Mureş (RO)
  • Presidio Ospedaliero (IT)
Corresponding author
Brignole, Michele
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2006-10
Volume
48
Issue
7
Pages
1425-1432
ISSN
0735-1097 (ISSN-L)
OpenAlex
W153798828
Cited by
165
References
31
Citations by year
2026: 3 · 2025: 11 · 2024: 8 · 2023: 3 · 2022: 7 · 2021: 9 · 2020: 10 · 2019: 12 · 2018: 10 · 2017: 17 · 2016: 9 · 2015: 9 · 2014: 11 · 2013: 12 · 2012: 7
FWCI
5.76
Type
journal article
Language
en
Open access
Locations
  • Journal of the American College of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Keywords
compression bandages, lower limb compression, abdominal compression, elastic compression stockings, elderly patients, tilt table test, systolic blood pressure, orthostatic symptoms, dizziness
MeSH terms
Abdomen, Age Factors, Aged, Bandages, Female, Humans, Hypotension, Orthostatic, Leg, Male, Pressure, Single-Blind Method, Treatment Outcome, Cross-Over Studies

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