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Dog allergen (Can f 1) and cat allergen (Fel d 1) in US homes: results from the National Survey of Lead and Allergens in Housing.

Arbes, Samuel J, Cohn, Richard D, Yin, Ming, Muilenberg, Michael L, Friedman, Warren, Zeldin, Darryl C·2004·Journal of Allergy and Clinical Immunology
DOI 10.1016/j.jaci.2004.04.036
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Abstract

Background Exposures to dog and cat allergens are believed to play important roles in the etiology of asthma; however, the levels of these allergens have never been assessed in a representative sample of US homes. Objective The objective of this study was to estimate and characterize exposures to Can f 1 (dog allergen) and Fel d 1 (cat allergen) in US homes. Methods Data were obtained from the National Survey of Lead and Allergens in Housing, a nationally representative survey of 831 US homes. Vacuumed-collected dust samples from the bed, bedroom floor, living room floor, and living room sofa were analyzed for concentrations of Can f 1 and Fel d 1 (micrograms of allergen per gram of dust). Results Although a dog or cat had lived in only 49.1% of homes in the previous 6 months, Can f 1 and Fel d 1 were detected in 100% and 99.9% of homes, respectively. Averaged over the sampled sites, geometric mean concentrations (microg/g) were 4.69 for Can f 1 and 4.73 for Fel d 1. Among homes with an indoor dog and cat, respectively, geometric mean concentrations were 69 for Can f 1 and 200 for Fel d 1. Among homes without the indoor pet, geometric mean concentrations were above 1.0. The independent predictors of elevated concentrations in homes without pets were all demographic variables that were also linked to a higher prevalence of pet ownership. Conclusions Can f 1 and Fel d 1 are universally present in US homes. Levels that have been associated with an increased risk of allergic sens…

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Research works printed but not linked: 30

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Metadata

Authors
Arbes, S. J., Cohn, R. D., Yin, M., Muilenberg, M. L., Friedman, W., & Zeldin, D. C.
Venue
Journal of Allergy and Clinical Immunology
Publisher
Elsevier BV
Published
2004-07
Volume
114
Issue
1
Pages
111-117
ISSN
0091-6749
DOI
10.1016/j.jaci.2004.04.036
Cited by
155
References
1
Language
en
Licence

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