Burden of allergic rhinitis: Results from the Pediatric Allergies in America survey
Open accessAbstract
Allergic rhinitis (AR), a chronic inflammatory disease of the upper airway, is one of the most common chronic diseases in the United States and is estimated to affect up to 60 million people. Pediatric Allergies in America is the largest and most comprehensive survey to date of pediatric patients and parents of patients with allergy, as well as health care providers (HCPs), regarding AR in children and its treatment. The goals of the survey were to determine the prevalence of AR in the US pediatric population and to collect information on what effect the condition has on patients in terms of symptom burden, quality of life, productivity, disease management, and pharmacologic treatment. This national survey screened 35,757 households to identify 500 children with HCP-diagnosed nasal allergies and 504 children without nasal allergies who were between the ages of 4 and 17 years. Parents of young children, as well as children 10 to 17 years of age, were questioned about the condition and its treatment. In parallel, 501 HCPs were interviewed. This survey has captured previously unavailable data on the prevalence of nasal allergies and their most common and most bothersome symptoms, on the effect of nasal allergies on the quality of life of children, and on medication use, including both over-the-counter and prescription medications, and has identified factors affecting satisfaction with treatment. The Pediatric Allergies in America survey also identifies distinct areas for improvement in the management of AR in children. In fact, based on the results of this survey, it appears that HCPs overestimate patients' and parents' satisfaction with disease management and the benefit of medications used for the treatment of nasal allergies in children. Findings from this national survey have identified important challenges to the management of AR, suggesting that its burden on children in the United States has been significantly underestimated.
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One population-based survey study of children with allergic rhinitis identified sleep disturbance due to allergic rhinitis as a significant factor affecting health-related quality of life.
“One population-based survey study of children with AR identified sleep disturbance due to AR as a significant factor affecting health-related QOL.2027”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [2027]
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- Authors
- Meltzer, E. O., Blaiss, M. S., Derebery, M. J., Mahr, T. A., Gordon, B. R., Sheth, K. K., Simmons, A. L., Wingertzahn, M. A., & Boyle, J. M.
- Affiliations
- Allergy and Asthma Medical Group and Research Center (US)
- University of Tennessee Health Science Center (US)
- House Clinic (US)
- Gundersen Lutheran Hospital (US)
- Arkansas Children's Hospital (US)
- Schulman, Ronca & Bucuvalas (US)
- Corresponding author
- Meltzer, Eli O.
- Venue
- Journal of Allergy and Clinical Immunology
- Publisher
- Elsevier BV
- Published
- 2009-09
- Volume
- 124
- Issue
- 3
- Pages
- S43-S70
- ISSN
- 0091-6749 (ISSN-L)
- OpenAlex
- W2049540404
- Cited by
- 553
- References
- 65
- Citations by year
- 2026: 15 · 2025: 28 · 2024: 36 · 2023: 50 · 2022: 35 · 2021: 43 · 2020: 38 · 2019: 29 · 2018: 26 · 2017: 28 · 2016: 41 · 2015: 36 · 2014: 37 · 2013: 35 · 2012: 24
- FWCI
- 19.24
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Allergy and Clinical Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
- Keywords
- allergic rhinitis, pediatric allergic rhinitis, symptom burden, quality of life, productivity, disease management, over-the-counter drugs, treatment satisfaction, prevalence, nasal allergy, healthcare provider perspectives
- MeSH terms
- Adolescent, Child, Child, Preschool, Female, Rhinitis, Allergic, Seasonal, Health Status, Humans, Male, Parents, Rhinitis, Allergic, Perennial, Sleep Wake Disorders, United States, Comorbidity, Prevalence, Patient Satisfaction, Cost of Illness
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