An association study of the m6A genes with major depressive disorder in Chinese Han population

Haploview: analysis and visualization of LD and haplotype maps

Barrett, J., Fry, B., Maller, J., & Daly, M. (2005) · Bioinform. · doi:10.1093/bioinformatics/bth457 · Cited by 15,086 · see citing works

The Epidemiology of Major Depressive Disorder: Results From the National Comorbidity Survey Replication (NCS-R)

Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., Rush, A. J., Walters, E. E., & Wang, P. S. (2003) · JAMA · doi:10.1001/jama.289.23.3095 · Cited by 7,988 · see citing works

The Structure of Haplotype Blocks in the Human Genome

Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. (2002) · Science · doi:10.1126/science.1069424 · Cited by 5,863 · see citing works

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Dominissini, D., Moshitch-Moshkovitz, S., Schwartz, S., Salmon-Divon, M., Ungar, L., Osenberg, S., Cesarkas, K., Jacob-Hirsch, J., Amariglio, N., Kupiec, M., et al. (2012) · Nature · doi:10.1038/nature11112 · Cited by 4,884 · see citing works

A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Frayling, T. M., Timpson, N. J., Weedon, M. N., Zeggini, E., Freathy, R. M., Lindgren, C. M., Perry, J. R. B., Elliott, K. S., Lango, H., Rayner, N. W., et al. (2007) · Science · doi:10.1126/science.1141634 · Cited by 4,531 · see citing works

Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study

Murray, C. J., & Lopez, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07495-8 · Cited by 4,492 · cited 1× · see citing works

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

Meyer, K. D., Saletore, Y., Zumbo, P., Elemento, O., Mason, C. E., & Jaffrey, S. R. (2012) · Cell · doi:10.1016/j.cell.2012.05.003 · Cited by 4,223 · see citing works

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

Jia, G., Fu, Y., Zhao, X., Dai, Q., Zheng, G., Yang, Y., Yi, C., Lindahl, T., Pan, T., Yang, Y.-G., et al. (2011) · Nature Chemical Biology · doi:10.1038/nchembio.687 · Cited by 4,106 · see citing works

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

Zheng, G., Dahl, J. A., Niu, Y., Fedorcsak, P., Huang, C.-M., Li, C. J., Vågbø, C. B., Shi, Y., Wang, W.-L., Song, S.-H., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2012.10.015 · Cited by 3,550 · see citing works

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

Liu, J., Yue, Y., Han, D., Wang, X., Fu, Y., Zhang, L., Jia, G., Yu, M., Lu, Z., Deng, X., et al. (2014) · Nature Chemical Biology · doi:10.1038/nchembio.1432 · Cited by 3,433 · see citing works

Genetic Epidemiology of Major Depression: Review and Meta-Analysis

Sullivan, P. F., Neale, M. C., & Kendler, K. S. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.10.1552 · Cited by 3,431 · see citing works

The molecular neurobiology of depression

Krishnan, V., & Nestler, E. J. (2008) · Nature · doi:10.1038/nature07455 · Cited by 2,889 · see citing works

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

Ping, X.-L., Sun, B.-F., Wang, L., Xiao, W., Yang, X., Wang, W.-J., Adhikari, S., Shi, Y., Lv, Y., Chen, Y.-S., et al. (2014) · Cell Research · doi:10.1038/cr.2014.3 · Cited by 2,375 · see citing works

Gene expression regulation mediated through reversible m6A RNA methylation

Fu, Y., Dominissini, D., Rechavi, G., & He, C. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3724 · Cited by 1,925 · see citing works

Excess mortality of mental disorder

Harris, C., & Barraclough, B. (1998) · British Journal of Psychiatry · doi:10.1192/bjp.173.1.11 · Cited by 1,881 · see citing works

Identification of Methylated Nucleosides in Messenger RNA from Novikoff Hepatoma Cells

Desrosiers, R. C., Friderici, K. H., & ROTTMAN, F. M. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.10.3971 · Cited by 1,761 · see citing works

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

Scuteri, A., Sanna, S., Chen, W.-M., Uda, M., Albai, G., Strait, J., Najjar, S., Nagaraja, R., Orrú, M., Usala, G., et al. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030115 · Cited by 1,724 · see citing works

Variation in FTO contributes to childhood obesity and severe adult obesity

Christian Dina, C., Meyre, D., Gallina, S., Durand, E., Körner, A., Jacobson, P., Carlsson, L. M. S., Kieß, W., Vatin, V., Lecœur, C., et al. (2007) · Nature Genetics · doi:10.1038/ng2048 · Cited by 1,620 · see citing works

m 6 A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

Geula, S., Moshitch-Moshkovitz, S., Dominissini, D., Mansour, A. A., Kol, N., Salmon‐Divon, M., Hershkovitz, V., Peer, E., Mor, N., Manor, Y. S., et al. (2015) · Science · doi:10.1126/science.1261417 · Cited by 1,560 · see citing works

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

Wang, Y., Li, Y., Toth, J. I., Petroski, M. D., Zhang, Z., & Zhao, J. C. (2014) · Nature Cell Biology · doi:10.1038/ncb2902 · Cited by 1,281 · see citing works

m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

Batista, P. J., Molinié, B., Wang, J., Qu, K., Zhang, J., Li, L., Bouley, D. M., Lujan, E., Haddad, B., Daneshvar, K., et al. (2014) · Cell stem cell · doi:10.1016/j.stem.2014.09.019 · Cited by 1,276 · see citing works

Pedigree disequilibrium tests for multilocus haplotypes.

Dudbridge, F. (2003) · Genetic Epidemiology · doi:10.1002/gepi.10252 · Cited by 1,135 · see citing works

A mega-analysis of genome-wide association studies for major depressive disorder

Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Byrne, E. M., Blackwood, D. H. R., Boomsma, D. I., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.21 · Cited by 1,120 · see citing works

RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

Fustin, J., Doi, M., Yamaguchi, Y., Hayashi, H., Nishimura, S., Yoshida, M., Isagawa, T., Morioka, M. S., Kakeya, H., Manabe, I., et al. (2013) · Cell · doi:10.1016/j.cell.2013.10.026 · Cited by 980 · see citing works

Economic burden of depression

Greenberg, P. E., Stiglin, L. E., Finkelstein, S. N., & Berndt, E. R. (1994) · PharmacoResources · doi:10.1007/bf03289581 · Cited by 974 · see citing works

Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase.

Bokar, J. A., Shambaugh, M. E., Polayes, D. A., Matera, A. G., & ROTTMAN, F. M. (1997) · PubMed Central · Cited by 961 · see citing works

Inactivation of the Fto gene protects from obesity

Fischer, J., Koch, L., Emmerling, C., Vierkotten, J., Peters, T., Brüning, J. C., & Rüther, U. (2009) · Nature · doi:10.1038/nature07848 · Cited by 943 · see citing works

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium (2015) · Nature Neuroscience · doi:10.1038/nn.3922 · Cited by 755 · see citing works

Likelihood-Based Association Analysis for Nuclear Families and Unrelated Subjects with Missing Genotype Data

Dudbridge, F. (2008) · Human Heredity · doi:10.1159/000119108 · Cited by 607 · see citing works

The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry

Hess, M. E., Heß, S., Meyer, K. D., Verhagen, L. A. W., Koch, L., Brönneke, H. S., Dietrich, M. O., Jordan, S. D., Saletore, Y., Elemento, O., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3449 · Cited by 546 · see citing works

A Population-Based Twin Study of Lifetime Major Depression in Men and Women

Kendler, K. S., & Prescott, C. A. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.1.39 · Cited by 512 · see citing works

The economic burden of depression

Stoudemire, A., Frank, R. W., Hedemark, N., Kamlet, M. S., & Blazer, D. G. (1986) · General Hospital Psychiatry · doi:10.1016/0163-8343(86)90018-6 · Cited by 480 · see citing works

Life Stress, Genes, and Depression: Multiple Pathways Lead to Increased Risk and New Opportunities for Intervention

Charney, D. S., & Manji, H. K. (2004) · Science s STKE · doi:10.1126/stke.2252004re5 · Cited by 426 · see citing works

Reversible RNA adenosine methylation in biological regulation

Jia, G., Fu, Y., & He, C. (2012) · Trends in Genetics · doi:10.1016/j.tig.2012.11.003 · Cited by 425 · see citing works

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

Boissel, S., Reish, O., Proulx, K., Kawagoe-Takaki, H., Sedgwick, B., Yeo, G. S. H., Meyre, D., Golzio, C., Molinari, F., Kadhom, N., et al. (2009) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2009.06.002 · Cited by 393 · see citing works

Emerging Roles of RNA Modification: m6A and U-Tail

Lee, M., Kim, B., & Kim, V. N. (2014) · Cell · doi:10.1016/j.cell.2014.08.005 · Cited by 331 · see citing works

Poor replication of candidate genes for major depressive disorder using genome-wide association data

Bosker, F. J., Hartman, C. A., Nolte, I. M., Prins, B. P., Terpstra, P., Posthuma, D., van Veen, T., Willemsen, G., DeRijk, R. H., de Geus, E. J., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.38 · Cited by 309 · see citing works

Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing

Mostafavi, S., Battle, A., Zhu, X., Potash, J. B., Weissman, M. M., Shi, J., Beckman, K., Haudenschild, C., McCormick, C., Mei, R., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.161 · Cited by 187 · see citing works

Wilms' tumor 1-associating protein regulates G 2 /M transition through stabilization of cyclin A2 mRNA

Horiuchi, K., Umetani, M., Minami, T., Okayama, H., Takada, S., Yamamoto, M. P., Aburatani, H., Reid, P., Housman, D. E., Hamakubo, T., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608357103 · Cited by 160 · see citing works

Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)

Thalhammer, A., Bencokova, Z., Poole, R., Loenarz, C., Adam, J., O′Flaherty, L., Schödel, J., Mole, D. R., Giaslakiotis, K., Schofield, C. J., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016210 · Cited by 151 · see citing works

RNA epigenetics

Liu, N., & Pan, T. (2014) · Translational research · doi:10.1016/j.trsl.2014.04.003 · Cited by 142 · see citing works

Role of RNA methyltransferases in tissue renewal and pathology

Blanco, S., & Frye, M. (2014) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2014.06.006 · Cited by 138 · see citing works

Genome-wide Methylomic Analysis of Monozygotic Twins Discordant for Adolescent Depression

Dempster, E. L., Wong, C. C. Y., Lester, K. J., Burrage, J., Gregory, A. M., Mill, J. S., & Eley, T. C. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.04.013 · Cited by 132 · see citing works

The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression

Samaan, Z., Anand, S., Zhang, X., Desai, D., Rivera, M., Pare, G., Thabane, L., Xie, C., Gerstein, H., Engert, J. C., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.160 · Cited by 129 · see citing works

Lifetime risk of depression: restricted to a minority or waiting for most?

Andrews, G., Poulton, R., & Skoog, I. G. (2005) · The British Journal of Psychiatry · doi:10.1192/bjp.187.6.495 · Cited by 90 · see citing works

Depressive disorder moderates the effect of the FTO gene on body mass index

Rivera, M., Cohen‐Woods, S., Kapur, K., Breen, G. D., Ng, M. Y., Butler, A. W., Craddock, N. J., Gill, M., Korszun, A., Maier, W., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.45 · Cited by 85 · see citing works

The effect of FTO rs9939609 on major depression differs across MDD subtypes

Milaneschi, Y., Lamers, F., Mbarek, H., Hottenga, J.-J., Boomsma, D. I., & Penninx, B. W. J. H. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.4 · Cited by 78 · see citing works

Fat mass and obesity-associated (FTO) protein interacts with CaMKII and modulates the activity of CREB signaling pathway

Li, L., Hales, C. M., Garber, K., & Jin, P. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu043 · Cited by 53 · see citing works

A cis-Phase Interaction Study of Genetic Variants Within the MAOA Gene in Major Depressive Disorder

Zhang, J., Chen, Y., Zhang, K., Yang, H., Sun, Y., Fang, Y., Shen, Y., & Xu, Q. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.06.004 · Cited by 45 · see citing works

Gender-specific role of the protein tyrosine phosphatase receptor type R gene in major depressive disorder

Shi, C., Zhang, K., & Xu, Q. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.10.026 · Cited by 18 · see citing works

Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01519-z · Cited by 246 · see citing works

Neuropathology of suicide: Recent findings and future directions

Lutz, P.-E., Mechawar, N., & Turecki, G. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.141 · Cited by 158 · see citing works

N6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1–Regulated Astrocyte Dysfunction and Depressive-like Behaviors

Huang, R., Zhang, Y., Bai, Y., Han, B., Ju, M., Chen, B., Yang, L., Wang, Y., Zhang, H., Zhang, H., et al. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.02.018 · Cited by 159 · see citing works

m6A RNA Methylation Controls Neural Development and Is Involved in Human Diseases

Du, K., Zhang, L., Lee, T., & Sun, T. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1138-1 · Cited by 153 · see citing works

Physical Exercise Prevented Stress‐Induced Anxiety via Improving Brain RNA Methylation

Yan, L., Wei, J., Yang, F., Wang, M., Wang, S., Cheng, T., Liu, X., Jia, Y., So, K., & Zhang, L. (2022) · Advanced Science · doi:10.1002/advs.202105731 · Cited by 83 · see citing works

Role of RNA modifications in brain and behavior

Jung, Y., & Goldman, D. (2018) · Genes, Brain and Behavior · doi:10.1111/gbb.12444 · Cited by 66 · see citing works

Epitranscriptome of the ventral tegmental area in a deep brain-stimulated chronic unpredictable mild stress mouse model

Song, N., Du, J., Gao, Y., & Yang, S. (2020) · Translational Neuroscience · doi:10.1515/tnsci-2020-0146 · Cited by 15 · see citing works

Association of Single Nucleotide Polymorphisms with Periodontitis in the Japanese Population.

Suzuki, A., Numabe, Y., & Kamoi, K. (2002) · 日本歯周病学会会誌 · doi:10.2329/perio.44.159 · Cited by 1 · see citing works

Clinically Defined Subtypes of Bipolar Disorder Are Reflected in Genomic Architecture

Werling, D. M. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.05.010 · Cited by 1 · see citing works

Identification of SNPs Affecting Porcine Carcass Weight with the 60K SNP Chip

Kang, K., Seo, D., Lee, J.-B., et al. (2013) · Journal of Animal Science and Technology · doi:10.5187/jast.2013.55.4.231 · Cited by 3 · see citing works

Association between the position-654G/A and-1429T/A single nucleotide polymorphisms(SNP) existing in 5′-regulatory region of β_2-adrenoceptor(β_2-AR) gene and risk of essential hypertension in Uighur of Xinjiang

Cheng, J. (2010) · Journal of Nongken Medicine

Are there different genotypes in Bipolar II and Bipolar I disorder and if so, why then do we tend to observe Unipolar Depression converting to Bipolar II and then converting to Bipolar I?

Fawcett, M., & Agius, M. A. (2015) · PubMed · Cited by 2 · see citing works