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Cited by 119Personality Traits and PsychologyPersonality Disorders and PsychopathologyAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Association of five-factor model personality domains and facets with presence, onset, and treatment outcomes of major depression in older adults

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Hayward, R. David, Taylor, Warren D., Smoski, Moria J., Steffens, David C., Payne, Martha E.·2013·The American Journal of Geriatric Psychiatry
DOI 10.1016/j.jagp.2012.11.012PMC PMC3382026
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Abstract

Objectives To assess the relationship of multiple domains and facets of the five-factor model of personality with presence, onset, and severity of late-life depression.Design Cross-sectional analysis of depression status, and age of onset. Retrospective analysis of baseline severity. Longitudinal analysis of severity after 3 and 12 months of psychiatric treatment.Setting Private university-affiliated medical center in the Southeastern United States.Participants One hundred twelve psychiatric patients with a current episode of unipolar major depression, and 104 nondepressed comparison subjects, age 60 and older (mean: 70, SD: 6).Measurements Revised NEO Personality Inventory, Diagnostic Interview Schedule, and Montgomery-Åsberg Depression Rating Scale.Results Binary logistic regression found that depression was related to higher neuroticism (and all its facets) and to lower extraversion (and facets of assertiveness, activity, and positive emotionality) and conscientiousness (and facets of competence, order, dutifulness, and self-discipline). Multinomial logistic regression found some of these relationships held only for depression with onset before age 50 (hostility, self-consciousness, extraversion, assertiveness, positive emotions, order, and dutifulness). Linear regression found that personality was unrelated to depression severity at the beginning of treatment, but improvement after 3 months was related to lower neuroticism (and facets depressiveness and stress-vulnerability) and higher warmth and competence. Improvement after 12 months was related to lower neuroticism, depressiveness, and stress-vulnerability.Conclusions Specific personality facets are related with depression and treatment outcomes. Screening for certain personality traits at the start of treatment may help identify patients at risk of worse response to treatment after 3 months.

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  • The present findings replicate and extend existing evidence that neuroticism, and vulnerability to stress specifically, affects both treatment response and cognitive decline in late-life major depression.

    “The present findings replicate and extend existing evidence for the impact of neuroticism, and VS specifically, on both treatment response and cognitive decline in LLD (18, 19).”

    From Neuroticism Traits Selectively Impact Long Term Illness Course and Cognitive Decline in Late-Life Depression (2017) · cites this paper as [19]

  • Preliminary evidence indicated that high total neuroticism and the vulnerability to stress trait were the only neuroticism scores associated with worse one-year antidepressant treatment response and two-year decline in global cognitive functioning in late-life major depression.

    “Our preliminary evidence indicated high total neuroticism and the VS trait were the only neuroticism scores associated with both a worse one-year antidepressant treatment response and a two-year decline in global cognitive functioning in LLD (18, 19).”

    From Neuroticism Traits Selectively Impact Long Term Illness Course and Cognitive Decline in Late-Life Depression (2017) · cites this paper as [19]

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Authors
Hayward, R. D., Taylor, W. D., Smoski, M. J., Steffens, D. C., & Payne, M. E.
Affiliations
  • University of Michigan (US)
  • Duke Medical Center (US)
Corresponding author
Hayward, R. David
ORCID
Venue
The American Journal of Geriatric Psychiatry
Publisher
Elsevier BV
Published
2013-01
Volume
21
Issue
1
Pages
88-96
ISSN
1064-7481 (ISSN-L)
DOI
10.1016/j.jagp.2012.11.012
PMC
PMC3382026
OpenAlex
W1965180119
Cited by
119
References
41
Citations by year
2026: 2 · 2025: 7 · 2024: 15 · 2023: 12 · 2022: 9 · 2021: 7 · 2020: 11 · 2019: 11 · 2018: 8 · 2017: 7 · 2016: 8 · 2015: 8 · 2014: 6 · 2013: 8
FWCI
11.13
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • American Journal of Geriatric Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (MH60451, K24MH070027, MH70027, R01MH054846, MH-54846, K23MH087754, P50MH060451)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
Big Five personality traits, personality facets, geriatric depression, major depressive disorder, neuroticism, extraversion, conscientiousness, depression onset, depression severity, treatment response, personality screening, older adults
MeSH terms
Aged, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Longitudinal Studies, Male, Models, Psychological, Personality, Personality Inventory, Retrospective Studies, Severity of Illness Index, Treatment Outcome, Age of Onset

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