Therapeutic glycoprotein production in mammalian cells

Cites (257)

Items 201–259 of 259

1. The combined effect of sodium butyrate and low culture temperature on the production, sialylation, and biological activity of an antibody produced in CHO cells
   Fei Chen, Tian-Ci Kou, Fan Li, Yan Zhou, Zhaoyang Ye, Liang Zhao, Wen‐Song Tan · 2011 · Biotechnology and Bioprocess Engineering
2. Generation of stable Chinese hamster ovary pools yielding antibody titers of up to 7. 6 g/L using the piggyBac transposon system
   Rajendra, Yashas, Peery, Robert B., Barnard, Gavin C. · 2016 · Biotechnology Progress
3. Autophagy and its implication in Chinese hamster ovary cell culture
   Kim, Yeon Jung, Baek, Eric, Lee, Jae Seong, Lee, Gyun Min · 2013 · Biotechnology Letters
4. Over-expression of Hsp70 in BHK-21 cells engineered to produce recombinant factor VIII promotes resistance to apoptosis and enhances secretion
   Ishaque, Adiba, Thrift, John, Murphy, John E., Konstantinov, Konstantin · 2007 · Biotechnology and Bioengineering
5. Anti-apoptotic genes Aven and E1B-19K enhance performance of BHK cells engineered to express recombinant factor VIII in batch and low perfusion cell culture
   Nivitchanyong, Toey, Martinez, Amanda, Ishaque, Adiba, Murphy, John E., Konstantinov, Konstantin, Betenbaugh, Michael J., Thrift, John · 2007 · Biotechnology and Bioengineering
6. Molecular characterization of a human matrix attachment region epigenetic regulator
   Arope, Salina, Harraghy, Niamh, Pjanic, Milos, Mermod, Nicolas · 2013 · PLoS ONE
7. Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases
   Carlage, Tyler, Kshirsagar, Rashmi, Zang, Li, Janakiraman, Vijay, Hincapie, Marina, Lyubarskaya, Yelena, Weiskopf, Andy, Hancock, William S. · 2012 · Biotechnology Progress
8. Profiling conserved microRNA expression in recombinant CHO cell lines using illumina sequencing
   Stephanie Hammond, Jeffrey C. Swanberg, Shawn W. Polson, Kelvin H. Lee · 2011 · Biotechnology and Bioengineering
9. Identification of a potent MAR element from the mouse genome and assessment of its activity in stable and transient transfections
   Harraghy, Niamh, Regamey, Alexandre, Girod, Pierre-Alain, Mermod, Nicolas · 2011 · Journal of Biotechnology
10. E2F-1 overexpression increases viable cell density in batch cultures of Chinese hamster ovary cells
    Majors, Brian S., Arden, Nilou, Oyler, George A., Chiang, Gisela G., Pederson, Nels E., Betenbaugh, Michael J. · 2008 · Journal of Biotechnology
11. Meganuclease-driven targeted integration in CHO-K1 cells for the fast generation of HTS-compatible cell-based assays
    Cabaniols, Jean-Pierre, Ouvry, Christine, Lamamy, Véronique, Fery, Isabelle, Craplet, Marie-Laure, Moulharat, Natacha, Guenin, Sophie-Pénélope, Bedut, Stéphane, Nosjean, Olivier, Ferry, Gilles et al. · 2010 · SLAS Discovery
12. The use of glutamine synthetase as a selection marker: recent advances in Chinese hamster ovary cell line generation processes
    Fan, Lianchun, Frye, Christopher C, Racher, Andrew J · 2013 · Pharmaceutical Bioprocessing
13. MAR elements regulate the probability of epigenetic switching between active and inactive gene expression
    Luis Galbete, José, Buceta, Montserrat, Mermod, Nicolas · 2008 · Molecular BioSystems
14. Expression of factor VIII in recombinant and transgenic systems
    Soukharev, Serguei, Hammond, David, Ananyeva, Natalya M, Anderson, Julia A.M, Hauser, Charlotte A.E, Pipe, Steven, Saenko, Evgueni L · 2002 · Blood Cells, Molecules, and Diseases
15. Glyco-Engineering of Human IgG-Fc to Modulate Biologic Activities
    Roy Jefferis · 2016 · Current Pharmaceutical Biotechnology
16. Large-Scale Transfection of Mammalian Cells
    Lucia Baldi, David L. Hacker, Carine Meerschman, Florian Maria Wurm · 2011 · Methods in molecular biology
17. Production of recombinant therapeutic proteins in human cells: current achievements and future perspectives
    Picanco-Castro, Virgínia, Biaggio, Rafael, Cova, Dimas, Swiech, Kamilla · 2013 · Protein & Peptide Letters
18. Profiling highly conserved microrna expression in recombinant IgG-producing and parental Chinese hamster ovary cells
    Lin, Nan, Davis, Angela, Bahr, Scott, Borgschulte, Trissa, Achtien, Katherine, Kayser, Kevin · 2011 · Biotechnology Progress
19. Reaching the depth of the Chinese hamster ovary cell transcriptome
    Jacob, Nitya M., Kantardjieff, Anne, Yusufi, Faraaz Noor Khan, Retzel, Ernest F., Mulukutla, Bhanu Chandra, Chuah, Song Hui, Yap, Miranda, Hu, Wei‐Shou · 2010 · Biotechnology and Bioengineering
20. Validation of the manufacturing process used to produce long‐acting recombinant factor IX Fc fusion protein
    Justin T. McCue, D. Osborne, J. Dumont, Robert Peters, Baisong Mei, Glenn F. Pierce, K. Kobayashi, Don Euwart · 2014 · Haemophilia
21. cMyc increases cell number through uncoupling of cell division from cell size in CHO cells
    Kuystermans, Darrin, Al-Rubeai, Mohamed · 2009 · BMC Biotechnology
22. Epigenetic regulatory elements: recent advances in understanding their mode of action and use for recombinant protein production in mammalian cells
    Harraghy, Niamh, Calabrese, David, Fisch, Igor, Girod, Pierre‐Alain, LeFourn, Valérie, Regamey, Alexandre, Mermod, Nicolas · 2015 · Biotechnology Journal
23. Structural analysis of recombinant von Willebrand factor produced at industrial scale fermentation of transformed CHO cells co-expressing recombinant furin
    Fischer, Bernhard E., Schlokat, Uwe, Mitterer, Artur, Reiter, Manfred, Mundt, Wolfgang, Turecek, Peter L., Schwarz, Hans P., Dorner, Friedrich · 1995 · FEBS Letters
24. Industrial production of clotting factors: challenges of expression, and choice of host cells
    Kumar, Sampath R. · 2015 · Biotechnology Journal
25. Engineering the Cellular Protein Secretory Pathway for Enhancement of Recombinant Tissue Plasminogen Activator Expression in Chinese Hamster Ovary Cells: Effects of CERT and XBP1s Genes
    Rahimpour, Azam · 2013 · Journal of Microbiology and Biotechnology
26. Using matrix attachment regions to improve recombinant protein production
    Harraghy, Niamh, Buceta, Montserrat, Regamey, Alexandre, Girod, Pierre-Alain, Mermod, Nicolas · 2012 · Methods in Molecular Biology
27. Specific inhibition of caspase-8 and −9 in CHO cells enhances cell viability in batch and fed-batch cultures
    Yun, Chee Yong, Liu, Sen, Lim, Sing Fee, Wang, Tianhua, Chung, Beatrice Y.F., Jiat Teo, Joong, Chuan, Kok Hwee, Soon, Allyson S.C., Goh, Keng Siong, Song, Zhiwei · 2007 · Metabolic Engineering
28. Deletion of a telomeric region on chromosome 8 correlates with higher productivity and stability of CHO cell lines
    Anett Ritter, Bernd Voedisch, Johannes Wienberg, Burkhard Wilms, Sabine Geisse, Thomas Jostock, Holger Laux · 2015 · Biotechnology and Bioengineering
29. Human hepatoma cell line HuH-7 is an effective cellular system to produce recombinant factor IX with improved post-translational modifications
    Enjolras, Nathalie, Dargaud, Yesim, Pérot, Eloïse, Guillaume, Florine, Becchi, Michel, Négrier, Claude · 2012 · Thrombosis Research
30. Increased in vivo effector function of human IgG4 isotype antibodies through afucosylation
    Gong, Qian, Hazen, Meredith, Marshall, Brett, Crowell, Susan R., Ou, Qinglin, Wong, Athena W., Phung, Wilson, Vernes, Jean-Michel, Meng, Y. Gloria, Tejada, Max et al. · 2016 · mAbs
31. Effect of XIAP overexpression on sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells producing erythropoietin
    Yeon‐Gu Kim, Jee Yon Kim, Gyun Min Lee · 2009 · Journal of Biotechnology
32. Disruption of the gene C12orf35 leads to increased productivities in recombinant CHO cell lines
    Anett Ritter, Tatjana Rauschert, Mevion Oertli, D. Piehlmaier, Panagiotis Mantas, Kuntzelmann Genevieve, Nadine Lageyre, Barbara Brannetti, Bernd Voedisch, Sabine Geisse et al. · 2016 · Biotechnology and Bioengineering
33. Production of Highly Sialylated Monoclonal Antibodies
    Raymond, Celine, Robotham, Anna, Kelly, John, Lattova, Erika, Perreault, Helene, Durocher, Yves · 2012 · Glycosylation
34. Improved expression of recombinant human factor IX by co-expression of GGCX, VKOR and furin
    Liu, Jianming, Jonebring, Anna, Hagström, Jonas, Nyström, Ann-Christin, Lövgren, Ann · 2014 · The Protein Journal
35. A small-scale method for the preparation of plant N-linked glycans from soluble proteins for analysis by MALDI-TOF mass spectrometry
    Karg, Saskia R., Frey, Alexander D., Ferrara, Claudia, Streich, Daniel K., Umaña, Pablo, Kallio, Pauli T. · 2009 · Plant Physiology and Biochemistry
36. Shire's replacement enzymes validate gene activation
    Nuala Moran · 2010 · Nature Biotechnology
37. Chemical manipulation of the mTORC1 pathway in industrially relevant CHOK1 cells enhances production of therapeutic proteins
    Dadehbeigi, Nazanin, Dickson, Alan J. · 2015 · Biotechnology Journal
38. Methods to create a stringent selection system for mammalian cell lines
    H. J. M. Van Blokland, Femke Hoeksema, Michel Siep, Arie P. Otte, John Verhees · 2011 · Cytotechnology
39. The use of a stringent selection system allows the identification of DNA elements that augment gene expression
    Hoeksema, Femke, van Blokland, Rik, Siep, Michel, Hamer, Karien, Siersma, Tjalling, den Blaauwen, Jan, Verhees, John, Otte, Arie P. · 2011 · Molecular Biotechnology
40. Evaluation of the OSCAR™ system for the production of monoclonal antibodies by CHO-K1 cells
    Costa, Ana Rita, Rodrigues, Maria Elisa, Henriques, Mariana, Melton, David, Cunnah, Philip, Oliveira, Rosário, Azeredo, Joana · 2012 · International Journal of Pharmaceutics
41. A one-step gene amplification system for use in cultured mammalian cells and transgenic animals
    Melton, David W., Ketchen, Ann-Marie, Kind, Alexander J., McEwan, Carolanne, Paisley, Derek, Selfridge, Jim · 2001 · Transgenic Research
42. Characterization and expression of proprotein convertases in CHO cells: efficient proteolytic maturation of human bone morphogenetic protein-7
    Sathyamurthy, Madhavi, Kim, Che Lin, Bang, You Lim, Kim, Young Sik, Jang, Ju Woong, Lee, Gyun Min · 2015 · Biotechnology and Bioengineering
43. Next-generation sequencing technologies and their potential impact on CHO cell-based biomanufacturing
    Benjamin G. Kremkow, Kelvin H. Lee · 2013 · Pharmaceutical Bioprocessing
44. CAP-T cell expression system: a novel rapid and versatile human cell expression system for fast and high yield transient protein expression
    Wölfel, Jens, Essers, Ruth, Bialek, Corinna, Hertel, Sabine, Scholz-Neumann, Nadine, Schiedner, Gudrun · 2011 · BMC Proceedings
45. Engineered mammalian chromosomes in cellular protein production: future prospects
    Kennard, Malcolm L. · 2011 · Methods in Molecular Biology
46. In vivo anti-tumor efficacy of afucosylated anti-CS1 monoclonal antibody produced in glycoengineered Pichia pastoris
    Gomathinayagam, Sujatha, Laface, Drake, Houston-Cummings, Nga Rewa, Mangadu, Ruban, Moore, Renee, Shandil, Ishaan, Sharkey, Nathan, Li, Huijuan, Stadheim, Terrance A., Zha, Dongxing · 2015 · Journal of Biotechnology
47. Fed-batch bioreactor performance and cell line stability evaluation of the artificial chromosome expression technology expressing an IgG1 in Chinese hamster ovary cells
    Combs, Rodney G., Yu, Erwin, Roe, Susanna, Piatchek, Michele Bailey, Jones, Heather L., Mott, John, Kennard, Malcolm L., Goosney, Danika L., Monteith, Diane · 2011 · Biotechnology Progress
48. Influence of the culprit lesion on clinical symptoms of coronary artery disease, with special emphasis on exercise data
    Kaufmann, Philipp, Mandinov, Lazar, Frielingsdorf, Juergen, Hess, Otto M. · 1998 · Coronary Artery Disease
49. Expression of glycoproteins with excellent glycosylation profile and serum half-life in CAP-Go cells
    Silke Wissing, Jens Wölfel, Helmut Kewes, Christian Niehus, Corinna Bialek, Sabine Hertel, Nicole Faust · 2015 · BMC Proceedings
50. Enhanced Proteolytic Processing of Recombinant Human Coagulation Factor VIII B-Domain Variants by Recombinant Furins
    Marcos Angelo Almeida Demasi, Erika de Simone Molina, Christian Bowman-Colin, Fernando Henrique Lojudice, Angelita G. Muras, Mari Cleide Sogayar · 2016 · Molecular Biotechnology
51. Protein Glycosylation: Analysis, Characterization, and Engineering
    Mikael Rørdam Andersen, Jong Hyun Nam, Susan T. Sharfstein · 2011 · Wiley eBooks
52. Cell Transfection
    Parminder S. Chahal, Yves Durocher, Amine Kamen · 2011 · Elsevier eBooks
53. Untitled work
    Ferrari · 1998 · 10.1002/(sici)1097-0290(19981205)60:5
54. Improvement of interferon-γ sialylation in Chinese hamster ovary cell culture by feeding ofN-acetylmannosamine
    Gu, Xuejun, Wang, Daniel I. C. · 1998 · Biotechnology and Bioengineering
55. Untitled work
    Rasheed · 1974 · 10.1002/1097-0142(197404)33:4
56. Untitled work
    Kim · 2000 · 10.1002/1097-0290(2000)71:3
57. Three-dimensional engineered heart tissue from neonatal rat cardiac myocytes
    Zimmermann, Wolfram H., Fink, Christine, Kralisch, Dirk, Remmers, Ute, Weil, Joachim, Eschenhagen, Thomas · 2000 · Biotechnology and Bioengineering
58. Addendum: Chinese hamster ovary cells can produce galactose-α-1, 3-galactose antigens on proteins
    Carlos J Bosques, Brian E Collins, James W Meador, Hetal Sarvaiya, Jennifer L Murphy, Guy DelloRusso, Dorota A Bulik, I-Hsuan Hsu, Nathaniel Washburn, Sandra F Sipsey et al. · 2011 · Nature Biotechnology
59. The Use of UCOE Vectors in Combination with a Preadapted Serum Free, Suspension Cell Line Allows for Rapid Production of Large Quantities of Protein
    Trish Benton, T. Chen, M. Mcentee, B. Fox, D. King, R. Crombie, T. Thomas, C. Bebbington · 2001 · Animal Cell Technology: From Target to Market