Augmentation of Treatment As Usual with online Cognitive Bias Modification of Interpretation training in adolescents with Obsessive Compulsive Disorder: A pilot study
Abstract
Background and objectives Cognitive Behavioral Therapy for children and adolescents with Obsessive Compulsive Disorder (OCD) is effective. However, since almost half of patients remain symptomatic after treatment, there remains room for improvement. Cognitive Bias Modification training of Interpretations (CBM-I) is a promising new intervention, as it targets misinterpretation of intrusions, which is seen as an important characteristic in OCD. To date, there have been no published studies of CBM-I in adolescents with OCD. The aim of the current pilot study was to examine the added value of online CBM-I training as an adjunctive treatment to the Treatment As Usual (TAU; that included CBT and pharmacotherapy) in adolescents with OCD.Methods Patients receiving TAU were randomly assigned to either an additional CBM-I training (n = 9), or to an additional placebo variant of this procedure (n = 7).Results Immediate, on-line interpretations changed in response to the CBM-I training, while no such effects were observed on slower retrospective off-line interpretations. Patients in the CBM-I training condition reported fewer obsessive compulsive symptoms after training, and clinicians rated them as having fewer obsessive symptoms (corresponding to medium-large effect sizes). No such changes were observed in the placebo group.Limitations The small sample size precludes strong conclusions and replication is necessary to test the robustness of the findings.Conclusions This small randomized controlled trial is suggestive, although not conclusive, regarding the promising additive value of OC-related CBM-I training as an adjunctive intervention to TAU in an adolescent clinical population.
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To the authors' knowledge there has been one other study where the effect of combining attention bias modification with regular treatment was investigated.
“To our knowledge there has been one other study where the effect of combining ABM with regular treatment was investigated.”
Salemink et al. conducted a small randomized study investigating the combination of cognitive-behavioral therapy with attention bias modification in adolescents with obsessive-compulsive disorder.
“Salemink et al. conducted a small randomized study, investigating the combination of cognitive-behavioral therapy (CBT) with ABM, finding that ABM-augmented CBT treatment in adolescents with obsessive-compulsive disorder (OCD) [73].”
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- Authors
- Salemink, E., Wolters, L., & de Haan, E.
- Affiliations
- De Bascule (NL)
- Amsterdam UMC Location University of Amsterdam (NL)
- Corresponding author
- Salemink, Elske
- Venue
- Journal of Behavior Therapy and Experimental Psychiatry
- Publisher
- Elsevier BV
- Published
- 2015-12
- Volume
- 49
- Issue
- Pt A
- Pages
- 112-119
- ISSN
- 0005-7916 (ISSN-L)
- OpenAlex
- W2005201699
- Cited by
- 54
- References
- 37
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 6 · 2022: 5 · 2021: 5 · 2020: 8 · 2019: 4 · 2018: 9 · 2017: 5 · 2016: 4 · 2015: 3
- FWCI
- 8.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Behavior Therapy and Experimental Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- UvA-DARE (University of Amsterdam) (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- Dutch Scientific Foundation (NWO VENI 451-10-029)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- obsessive-compulsive disorder, adolescents, online training, adjunctive therapy, cognitive behavioral therapy, intrusive thoughts, misinterpretation, usual care, placebo comparison
- MeSH terms
- Adolescent, Analysis of Variance, Cognition, Female, Humans, Male, Obsessive-Compulsive Disorder, Online Systems, Pilot Projects, Psychiatric Status Rating Scales, Reaction Time, Cognitive Behavioral Therapy, Bias, Treatment Outcome, Recognition, Psychology, Feedback, Psychological, Self Report
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