Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders

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Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework

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Astrocyte-endothelial interactions at the blood-brain barrier

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Astrocytes: Biology and pathology

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Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*

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Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

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Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

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Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

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Long Noncoding RNAs: Cellular Address Codes in Development and Disease

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Neuroglial Advances: New Roles for Established Players

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Extracellular Vesicles and HIV-Associated Neurocognitive Disorders: Implications in Neuropathogenesis and Disease Diagnosis

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Perspective insights into hydrogels and nanomaterials for ischemic stroke

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Exo-hydrogel therapy: a revolutionary approach to managing diabetic complications

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Simvastatin Prevents Neurodegeneration in the MPTP Mouse Model of Parkinson’s Disease via Inhibition of A1 Reactive Astrocytes

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Brain Tissue-Derived Extracellular Vesicle Mediated Therapy in the Neonatal Ischemic Brain

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The role of exosomes in central nervous system tissue regeneration and repair

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The role of neuroglial cells communication in ischemic stroke

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Astrocyte-derived sEVs alleviate fibrosis and promote functional recovery after spinal cord injury in rats

Lu, Y., Chen, C., Wang, H., Du, R., Ji, J., Xu, T., Yang, C., & Chen, X. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109322 · Cited by 17

Sodium Butyrate Supplementation Modulates Neuroinflammatory Response Aggravated by Antibiotic Treatment in a Mouse Model of Binge-like Ethanol Drinking

Gao, L., Davies, D. L., & Asatryan, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415688 · Cited by 16

Ultrasound and neuroinflammation: immune modulation via the heat shock response

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Alzheimer’s Disease, Obesity, and Type 2 Diabetes: Focus on Common Neuroglial Dysfunctions (Critical Review and New Data on Human Brain and Models)

Tolédano, A., Rodríguez‐Casado, A., Álvarez, M., & Toledano‐Díaz, A. (2024) · Brain Sciences · doi:10.3390/brainsci14111101 · Cited by 19

Intranasal delivery of hMSC-derived supernatant for treatment of ischemic stroke by inhibiting the pro-inflammatory polarization of neutrophils

Jiang, Y., Wang, N., Liu, J., Ren, H., Jiang, W., Lei, Y., Fu, X., Hao, M., Lang, X., Liu, Y., et al. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04172-1 · Cited by 16

Engineering Extracellular Vesicles Secreted by Human Brain Organoids with Different Regional Identity

Liu, C., Chen, X., Ene, J., Esmonde, C., Kanekiyo, T., Zeng, C., Sun, L. J., & Li, Y. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c22692 · Cited by 17

Antinociceptive Effects of Aaptamine, a Sponge Component, on Peripheral Neuropathy in Rats

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Exercise alleviates cisplatin-induced toxicity in the hippocampus of mice by inhibiting neuroinflammation and improving synaptic plasticity

Park, S. H., Ko, J. R., & Han, J. (2024) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2024.28.2.145 · Cited by 16

Exosomes: The endogenous nanomaterials packed with potential for diagnosis and treatment of neurologic disorders

Tang, X., He, Y., Liu, J., Xu, J., & Peng, Q. (2024) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2024.113938 · Cited by 17

Neural and Glial Regulation of Angiogenesis in CNS in Ischemic Stroke

Grinchevskaya, L. R., Salikhova, D. I., Silachev, D. N., & Goldshtein, D. V. (2024) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-024-06219-4 · Cited by 16

Mesenchymal Stem Cell-Derived Extracellular Vesicles: Emerging Therapies for Neurodegenerative Diseases

Chen, P., Wang, F., Ling, B., Zhu, Y., Lin, H., Huang, J., & Wang, X.-L. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s526945 · Cited by 16

iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles

Gordillo-Sampedro, S., Antounians, L., Wei, W., Mufteev, M., Lendemeijer, B., Kushner, S. A., de Vrij, F. M. S., Zani, A., & Ellis, J. (2024) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2024.103933 · Cited by 15

Research progress on astrocyte-derived extracellular vesicles in the pathogenesis and treatment of neurodegenerative diseases

Zhu, Y., Wang, F., Xia, Y., Wang, L., Lin, H., Zhong, T., & Wang, X. (2024) · Reviews in the Neurosciences · doi:10.1515/revneuro-2024-0043 · Cited by 15

Profiling biomanufactured extracellular vesicles of human forebrain spheroids in a Vertical‐Wheel Bioreactor

Liu, C., Sun, L. J., Worden, H., Ene, J., Zeng, O. Z., Bhagu, J., Grant, S. C., Bao, X., Jung, S., & Li, Y. (2024) · Journal of Extracellular Biology · doi:10.1002/jex2.70002 · Cited by 16

Refining the interactions between microglia and astrocytes in Alzheimer’s disease pathology

Chen, J., Xu, S., Wang, L., Liu, X., Liu, G., Tan, Q., Li, W., Zhang, S., & Du, Y. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.03.033 · Cited by 17

Extracellular Vesicle-Encapsulated miR-183-5p from Rhynchophylline-Treated H9c2 Cells Protect against Methamphetamine-Induced Dependence in Mouse Brain by Targeting NRG1

Zhou, Y., Shilin, X., Li, C., Chen, Z., Chen, Z., Zhou, Q., Ou, J., Li, J., Chen, Y., Luo, C., et al. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/2136076 · Cited by 14

Complications of COVID-19 on the Central Nervous System: Mechanisms and Potential Treatment for Easing Long COVID

Wei, Z. D., Liang, K., & Shetty, A. K. (2023) · Aging and Disease · doi:10.14336/ad.2023.0312 · Cited by 17

Revolutionizing medicine: Harnessing plant-derived vesicles for therapy and drug transport

Li, L., Li, Z., Liu, X., Zhang, W., Zhang, Y., Liang, Y., Zhang, Z., Li, Y., Ding, M., Li, R., et al. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e40127 · Cited by 19

Astrocytes: Therapeutic targets for stroke

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The Multifaceted Role of LRRK2 in Parkinson’s Disease

Ho, D. H., Han, S. J., & Son, I. (2025) · Brain Sciences · doi:10.3390/brainsci15040407 · Cited by 14

Strategies to rescue mitochondria in Parkinson’s disease: The significance of mitochondrial transfer

Liang, J., Su, Z., Su, G., Rasheed, M., Tang, S., Sunniya, H., Maazouzi, M., Cui, Y., Wang, J., Wang, X., et al. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102856 · Cited by 14

Activity and Heterogeneity of Astrocytes in Neurological Diseases: Molecular Mechanisms and Therapeutic Targets

Mao, S., Qiao, R., Wang, Q., Shen, L., Li, D., Huo, X., Wang, J., Liu, K., Chen, W., Zhu, T., et al. (2025) · MedComm · doi:10.1002/mco2.70329 · Cited by 17

Exosomes in Vascular/Neurological Disorders and the Road Ahead

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Glial cells improve Parkinson’s disease by modulating neuronal function and regulating neuronal ferroptosis

Li, M., Chen, M., Li, H., Gao, D., Zhao, L., & Zhu, M. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1510897 · Cited by 17

Engineering extracellular vesicles for Alzheimer's disease: An emerging cell‐free approach for earlier diagnosis and treatment

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High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway

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Interactions between astrocytes and cerebral endothelial cells in central nervous system diseases

Sun, J., & He, Z. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118516 · Cited by 13

MiR-184 Mediated the Expression of ZNF865 in Exosome to Promote Procession in the PD Model

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Astrocyte-derived exosomes-transported miRNA-26a-5p ameliorates sevoflurane-induced cognitive dysfunction in aged mice

Li, J., Xu, H., Zhang, K., Liu, Y., Zeng, C., Fu, Y., & Li, Y. (2024) · Translational research · doi:10.1016/j.trsl.2024.01.007 · Cited by 13

Proteomic insights into extracellular vesicles in ALS for therapeutic potential of Ropinirole and biomarker discovery

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DICAM in the Extracellular Vesicles from Astrocytes Attenuates Microglia Activation and Neuroinflammation

Han, J., Cho, H.-J., Park, D., & Han, S. (2022) · Cells · doi:10.3390/cells11192977 · Cited by 13

The Dual Role of Astrocyte-Derived Exosomes and Their Contents in the Process of Alzheimer’s Disease

Liu, Z., Zhang, H., Liu, S., Hou, Y., & Chi, G. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-220698 · Cited by 14

Exosomal TAR DNA binding protein 43 profile in canine model of amyotrophic lateral sclerosis: a preliminary study in developing blood-based biomarker for neurodegenerative diseases

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MCP-1 levels in astrocyte-derived exosomes are changed in preclinical stage of Alzheimer's disease

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The Interplay Between Exosomes and Gut Microbiota in Neuroinflammation: A New Frontier in Alzheimer’s Disease

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Differential expression of miR‐1249‐3p and miR‐34b‐5p between vulnerable and resilient phenotypes of cocaine addiction

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Modulating Lineage Specification in Stem Cell Differentiation via Bioelectrical Stimulation Intensity Matching

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A novel function and mechanism of ischemia-induced retinal astrocyte-derived exosomes for RGC apoptosis of ischemic retinopathy

Ye, X., Liu, Y., Chen, C., Sun, Y., Li, F., Fu, Y., Luo, J., Su, L., & Chi, W. (2024) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2024.102209 · Cited by 13

Astrocyte-derived apolipoprotein D is required for neuronal survival in Parkinson’s disease

Dai, Y., Bi, M., Jiao, Q., Du, X., Yan, C., & Jiang, H. F. (2024) · npj Parkinson s Disease · doi:10.1038/s41531-024-00753-8 · Cited by 11

Exploring the role of brain-derived extracellular vesicles in viral infections: from pathological insights to biomarker potential

Oberholster, L., Pasquier, R. D., & Mathias, A. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1423394 · Cited by 11

Recent Advances in the miRNA-Mediated Regulation of Neuronal Differentiation and Death

Patranabis, S. (2024) · NeuroMolecular Medicine · doi:10.1007/s12017-024-08820-2 · Cited by 12

Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage

Li, K., Liu, Y., Gong, J., Li, J., Zhao, M., Hong, C., Zhang, Y., He, M., Zhu, Z., Chen, Z., et al. (2025) · Fluids and Barriers of the CNS · doi:10.1186/s12987-025-00651-y · Cited by 11

Prospects of engineered exosomes in clinical applications: a review

Li, Y., Meng, D., Cheng, Y., Sun, Y., Dong, Y., Shi, J., Wan, G., & Deng, C. (2025) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2025.2541789 · Cited by 11

A novel regulator in Alzheimer's disease progression: The astrocyte-derived extracellular vesicles

Li, B., Ma, Z., & Li, Z. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101871 · Cited by 11

Extracellular Vesicles: Therapeutic Potential in Central Nervous System Trauma by Regulating Cell Death

Chen, Y., Zhang, H., Hu, X., Cai, W., Jiang, L., Wang, Y., Wu, Y., Wang, X., Ni, W., & Zhou, K. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03501-w · Cited by 12

Astrocyte-derived extracellular vesicles inhibit the abnormal activation of immune function in neonatal mice with hypoxic-ischemic brain damage by carrying miR-124-3p

Li, L., & Li, M. (2023) · Neurological Research · doi:10.1080/01616412.2023.2257416 · Cited by 11

Extracellular Vesicles in Alzheimer’s Disease: Dual Roles in Pathogenesis, Promising Avenues for Diagnosis and Therapy

Li, F., Wu, L., Feng, X., Li, Y., & Fan, H. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18010070 · Cited by 10

Promise of mesenchymal stem cell-derived extracellular vesicles for alleviating subarachnoid hemorrhage-induced brain dysfunction by neuroprotective and antiinflammatory effects

Sankarappan, K. K., & Shetty, A. K. (2024) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2024.100835 · Cited by 10

Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix‐Dependent Manner for Spinal Cord Repair Applications

O’Connor, C., Woods, I., McComish, S. F., Kerr, S., McGrath, M., Chávez, J. C. P., Maughan, J., McGuire, T. K., Caldwell, M. A., Dervan, A. G., et al. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202500830 · Cited by 9

The age-associated decline in neuroplasticity and its implications for post-stroke recovery in animal models of cerebral ischemia: The therapeutic role of extracellular vesicles

Popa‐Wagner, A., Hermann, D. M., Doeppner, T. R., Surugiu, R., & Pîrșcoveanu, D. F. V. (2025) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x251365020 · Cited by 15

IL-6-Mediated Upregulated miRNAs in Extracellular Vesicles Derived from Lund Human Mesencephalic (LUHMES) Cells: Effects on Astrocytes and Microglia

Nishi, K., Izumi, H., Tomonaga, T., Nagano, C., Morimoto, Y., & Horie, S. (2023) · Biomolecules · doi:10.3390/biom13050718 · Cited by 10

5-Repurposed Drug Candidates Identified in Motor Neurons and Muscle Tissues with Amyotrophic Lateral Sclerosis by Network Biology and Machine Learning Based on Gene Expression

Temiz, K., Gül, A., & Göv, E. (2025) · NeuroMolecular Medicine · doi:10.1007/s12017-025-08847-z · Cited by 9

Glial and blood-brain barrier cell-derived exosomes: Implications in stroke

Mathias, K., Machado, R. S., Petronilho, T., Sulzbacher, V. A. R., de Rezende, V. L., Prophiro, J. S., & Petronilho, F. C. (2025) · Microvascular Research · doi:10.1016/j.mvr.2025.104812 · Cited by 10

Deciphering Molecular and Signaling Pathways of Extracellular Vesicles-Based Therapeutics for Alzheimer’s Disease

Dhapola, R., Kumari, S., Sharma, P., Paidlewar, M., Medhi, B., Vellingiri, B., & HariKrishnaReddy, D. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05216-6 · Cited by 9

The complement cascade in Alzheimer’s disease: modern implications of an ancient immune protagonist

Papavergi, M.-T., Bathini, P., Singh, B. B., & Lemere, C. A. (2025) · Molecular Neurodegeneration · doi:10.1186/s13024-025-00916-y · Cited by 12

The Dual Role of Extracellular Vesicles in Aging and Age-Related Diseases: Pathophysiology and Therapeutic Potential

Zhu, Y., Fang, X., Zhang, S., Liao, Y., Lin, H., Chen, P., Yang, M., Huang, J. J., & Wang, X. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s589123 · Cited by 14

Prominosomes - a particular class of extracellular vesicles containing prominin-1/CD133?

Karbanová, J., Thamm, K., Fargeas, C. A., Deniz, I. A., Lorico, A., & Corbeil, D. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03102-w · Cited by 10

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Salim, M. W., Zhang, W., Collins‐Praino, L. E., Wang, Y., & Care, A. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202504608 · Cited by 8

Brain-Derived Exosomal miRNA Profiles upon Experimental SAE Rats and Their Comparison with Peripheral Exosomes

Xiao, Q., Yan, X., Sun, Y., Tang, Y., Hou, R., Pan, X., & Zhu, X. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03569-4 · Cited by 9

Optimization, Characterization and In-Vitro Cellular Uptake of Donepezil-Loaded NanoCrystVesicles

Dhiman, A., Tandon, R., Ahirwar, K., Handa, M., Srivastava, N., & Shukla, R. (2024) · Journal of Cluster Science · doi:10.1007/s10876-024-02608-x · Cited by 8

Collagen I Microfiber Promotes Brain Capillary Network Formation in Three–Dimensional Blood–Brain Barrier Microphysiological Systems

Nakayama-Kitamura, K., Shigemoto‐Mogami, Y., Piantino, M., Naka, Y., Yamada, A., Kitano, S., Furihata, T., Matsusaki, M., & Sato, K. (2024) · Biomedicines · doi:10.3390/biomedicines12112500 · Cited by 8

Astrocytes and Astrocyte-Derived Extracellular Conduits in Opiate-Mediated Neurological Disorders

Ray, S., Datta, S., Saha, A., & Sil, S. (2025) · Cells · doi:10.3390/cells14181454 · Cited by 9

Impact of Astrocytic Coverage of Synapses on the Short-Term Memory of a Computational Neuron-Astrocyte Network

Li, Z., Tsybina, Y., Gordleeva, S., & Zaikin, A. A. (2022) · Mathematics · doi:10.3390/math10183275 · Cited by 6

New insights on targeting extracellular vesicle release by GW4869 to modulate lipopolysaccharide-induced neuroinflammation in mice model

Liu, X., Meng, P., Liu, Z., Tian, X., Xi, J., Du, M., Yang, H., & Long, Q. (2024) · Nanomedicine · doi:10.1080/17435889.2024.2422811 · Cited by 7

Multiple roles of neuronal extracellular vesicles in neurological disorders

Jiao, Z., He, Z., Liu, N., Lai, Y., & Zhong, T. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.979856 · Cited by 7

Human hippocampal astrocytes: Computational dissection of their transcriptome, sexual differences and exosomes across ageing and mild‐cognitive impairment

Guebel, D. V. (2023) · European Journal of Neuroscience · doi:10.1111/ejn.16081 · Cited by 7

Ubiquinone Metabolism and Transcription HIF-1 Targets Pathway Are Toxicity Signature Pathways Present in Extracellular Vesicles of Paraquat-Exposed Human Brain Microvascular Endothelial Cells

Vujić, T., Schvartz, D., Iliuk, A. B., & Sanchez, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105065 · Cited by 7

The Essential Role of Astrocytes in Neurodegeneration and Neuroprotection

Couselo, F. L., Saba, J., Carniglia, L., Durand, D., Lasaga, M., & Caruso, C. M. (2023) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/0118715273269881231012062255 · Cited by 6

Extracellular Vesicles in Chronic Demyelinating Diseases: Prospects in Treatment and Diagnosis of Autoimmune Neurological Disorders

Ovchinnikova, L. A., Zalevsky, A. O., & Lomakin, Y. A. (2022) · Life · doi:10.3390/life12111943 · Cited by 6

Rab11A Depletion in Microglia-Derived Extracellular Vesicle Proteome upon Beta-Amyloid Treatment

Mignogna, G., Fabrizi, C., Correani, V., Giorgi, A., & Maras, B. (2023) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-023-01133-4 · Cited by 6

Human Adult Astrocyte Extracellular Vesicle Transcriptomics Study Identifies Specific RNAs Which Are Preferentially Secreted as EV Luminal Cargo

Shanthi, K., Fischer, D., Sharma, A., Kiviniemi, A., Kaakinen, M., Vainio, S., & Bart, G. (2023) · Genes · doi:10.3390/genes14040853 · Cited by 5

Nanoscale Glutathione-Functionalized Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Loaded with Metformin for the Treatment of Spinal Cord Injury

Zou, Z., Wen, S., Yu, Q., Li, Y., An, J., Xiong, Y., Wu, Q., Tong, L., Wu, C., Mei, X., et al. (2023) · ACS Applied Nano Materials · doi:10.1021/acsanm.3c03712 · Cited by 5

Update on the roles and applications of extracellular vesicles in depression

Wu, J., Lu, J. L., Pan, M.-Z., Gu, X., Dai, L., Wang, Y., Shen, B., & Zhang, X.-B. (2025) · World Journal of Psychiatry · doi:10.5498/wjp.v15.i3.102643 · Cited by 5

Extracellular vesicles as multiorgan crosstalk mediators in cardiovascular diseases: emerging biomarkers and therapeutic targets

Meng, F., Lixia, Z., Zhang, B., Wang, Y., Bai, Y., Han, Y., Wang, L., & Xu, J. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177976 · Cited by 5

Human Stem Cell-Derived Extracellular Vesicles: A Pioneering Path from Biogenesis to Cerebral Ischemic Stroke Therapy

Roy, A., Driscoll, T. P., Grant, S. C., & Li, Y. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262110550 · Cited by 5

Pharmacological modulation of the blood-brain barrier: Mechanisms, therapeutic strategies, and emerging technologies

Pediaditakis, I., Tsakali, S., Lemieux, M. R., Brennan, M., Robinson, W. H., Papapetropoulos, S., & Papapetropoulos, A. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100118 · Cited by 8

The identification of a Distinct Astrocyte Subtype that Diminishes in Alzheimer’s Disease

Wei, H., Withrow, J. S., Rakshit, J., Amin, F. U., Nahm, J., Mowry, F. E., Mao, Z., Bhattacharjee, M. B., Zhu, J., Yang, Y., et al. (2024) · Aging and Disease · doi:10.14336/ad.2024.0205-1 · Cited by 7

Non-Invasive Assessment of Neurogenesis Dysfunction in Fetuses with Early-Onset Growth Restriction Using Fetal Neuronal Exosomes Isolating from Maternal Blood: A Pilot Study

Gusar, V. A., Кан, Н. Е., Leonova, A., Chagovets, V., Tyutyunnik, V., Khachatryan, Z. V., Львовна, Я. Е., & Sukhikh, G. T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26041497 · Cited by 5

Astrocyte-derived extracellular vesicular NFIA mediates obesity-associated cognitive impairment

Wu, L., Deng, L., Xu, X., Chang, H., Liu, C., Wu, J., Zhang, C., Wang, R., Gao, R., Chen, H., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03473-9 · Cited by 5

Research Progress on Exosomes and MicroRNAs in the Microenvironment of Postoperative Neurocognitive Disorders

Huang, Q., Zhou, Y., He, H., Lin, S., & Chen, X. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03785-9 · Cited by 5

Tissue Engineering as a Promising Treatment for Glottic Insufficiency: A Review on Biomolecules and Cell-Laden Hydrogel

Ng, W.-C., Lokanathan, Y., Baki, M. M., Fauzi, M. B., Zainuddin, A. A., & Azman, M. B. (2022) · Biomedicines · doi:10.3390/biomedicines10123082 · Cited by 5

Synergism Between Hypothalamic Astrocytes and Neurons in Metabolic Control

Frago, L. M., Gómez-Romero, A., Collado‐Perez, R., Argente, J., & Chowen, J. A. (2024) · Physiology · doi:10.1152/physiol.00009.2024 · Cited by 5

Rab8a/SNARE complex activation promotes vesicle anchoring and transport in spinal astrocytes to drive neuropathic pain

Xiao, Y., Wang, G., He, G., Qin, W., & Shi, Y. (2024) · Biomolecules and Biomedicine · doi:10.17305/bb.2024.10441 · Cited by 5

The Application of MicroRNAs in Traumatic Brain Injury: Mechanism Elucidation and Clinical Translation

Wang, H., Fan, X., Zhang, Y., Ma, N., Li, L., Lü, Q., Wang, Q., Yu, B., Li, X., & Gao, J. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04737-4 · Cited by 5

Astrocyte-derived extracellular vesicles mediate intercellular communications of the neurogliovascular unit

Pivoriūnas, A., & Verkhratsky, A. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.300994 · Cited by 5

Lab-on-a-chip for biomarker detection: advances, practical applications, and future perspectives

Xu, T., Bai, H., Hu, J., Zhang, L., Zhuang, W., Zou, C., Yao, Y., Hu, W. W., & Huang, J. (2026) · Lab on a Chip · doi:10.1039/d5lc00986c · Cited by 7

Glial Plasticity and Dysfunction: Mechanistic Insights and Therapeutic Opportunities in Neurodegeneration

Correale, J. D. (2026) · Journal of Neurochemistry · doi:10.1111/jnc.70414 · Cited by 4

Extracellular vesicles—Mediators of opioid use disorder?

Morris, D. C., Zacharek, A., Zhang, Z. G., & Chopp, M. (2023) · Addiction Biology · doi:10.1111/adb.13353 · Cited by 3

Ginsenoside reprogramming microglia through the FGF/FGFR1 inhibits post traumatic stress disorder

Zhou, H., Pan, H., Li, X., Huang, L., Zhang, R., Yan, X., & Xu, J. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113763 · Cited by 4

Dual role of extracellular vesicles in neurodegenerative diseases

Scuteri, A., & Donzelli, E. (2024) · World Journal of Stem Cells · doi:10.4252/wjsc.v16.i12.1002 · Cited by 5

Astrocyte-derived extracellular vesicles: A double-edged sword in central nervous system disorders

Zhao, S., Sheng, S., Wang, Y., Ding, L., Xu, X., Xia, X., & Zheng, J. C. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.027 · Cited by 90

Neuroprotective Effects of Astrocyte Extracellular Vesicles in Stroke

Yakovlev, A. A. (2022) · Neurochemical Journal · doi:10.1134/s1819712422020143 · Cited by 7

Research progress on astrocyte-derived extracellular vesicles in the pathogenesis and treatment of neurodegenerative diseases

Zhu, Y., Wang, F., Xia, Y., Wang, L., Lin, H., Zhong, T., & Wang, X. (2024) · Reviews in the Neurosciences · doi:10.1515/revneuro-2024-0043 · Cited by 15

Therapeutic potential of astrocyte-derived extracellular vesicles in mitigating cytotoxicity and transcriptome changes in human brain endothelial cells

Stewart, R., Hutson, K. H., & Nestorova, G. G. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.09.040 · Cited by 6

Activated human astrocyte‐derived extracellular vesicles modulate neuronal uptake, differentiation and firing

You, Y., Borgmann, K., Edara, V. V., Stacy, S., Ghorpade, A., & Ikezu, T. (2020) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2019.1706801 · Cited by 176