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Comparing Viral Vectors and Fate Mapping Approaches for Astrocyte-to-Neuron Reprogramming in the Injured Mouse Cerebral Cortex

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Interlaminar and varicose-projection astrocytes: toward a new understanding of the primate brain

Ciani, C., & Falcone, C. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1477753 · Cited by 11 · see citing works

Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage

Li, K., Liu, Y., Gong, J., Li, J., Zhao, M., Hong, C., Zhang, Y., He, M., Zhu, Z., Chen, Z., et al. (2025) · Fluids and Barriers of the CNS · doi:10.1186/s12987-025-00651-y · Cited by 11 · see citing works

Advancements in extracellular vesicle therapy for neurodegenerative diseases

Hu, N., Chen, L., Hu, G., & Ma, R. (2025) · Exploration of Neuroprotective Therapy · doi:10.37349/ent.2025.1004104 · Cited by 11 · see citing works

Contributing to Understand the Crosstalk between Brain and Periphery in Methylmercury Intoxication: Neurotoxicity and Extracellular Vesicles

Arrifano, G. D. P., Augusto‐Oliveira, M., Sealey-Bright, M., Zainal, J., Imbiriba, L. C., Fernandes, L. M. P., Maia, C. D. S. F., Anthony, D. C., & Lopez, M. E. C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910855 · Cited by 11 · see citing works

Extracellular Vesicles in Alzheimer’s Disease: Dual Roles in Pathogenesis, Promising Avenues for Diagnosis and Therapy

Li, F., Wu, L., Feng, X., Li, Y., & Fan, H. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18010070 · Cited by 10 · see citing works

Emerging roles of extracellular vesicles in mediating RNA virus infection

Xia, X., Wang, Y., & Zheng, J. (2021) · Fundamental Research · doi:10.1016/j.fmre.2021.02.005 · Cited by 10 · see citing works

Expression analysis and targets prediction of microRNAs in OGD/R treated astrocyte-derived exosomes by smallRNA sequencing

Wang, Z., Xu, F., Zhao, X., Zhang, Y., Wang, X., Zhang, Z., Yang, L. Z., Badshah, J. S., Xu, B., Xie, R., et al. (2023) · Genomics · doi:10.1016/j.ygeno.2023.110594 · Cited by 8 · see citing works

Membrane Charge Drives the Aggregation of TDP-43 Pathological Fragments

Corucci, G., Vadukul, D. M., Paracini, N., Laux, V., Batchu, K. C., Aprile, F. A., & Pastore, A. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c00594 · Cited by 7 · see citing works

Lysyl oxidase like-1 deficiency in optic nerve head astrocytes elicits reactive astrocytosis and alters functional effects of astrocyte derived exosomes

Hariani, H. N., Ghosh, A. K., Rosen, S., Tso, H., Kessinger, C., Zhang, C., Jones, W. K., Sappington, R. M., Mitchell, C. H., Stubbs, E. B., et al. (2024) · Experimental Eye Research · doi:10.1016/j.exer.2024.109813 · Cited by 7 · see citing works

New insights on targeting extracellular vesicle release by GW4869 to modulate lipopolysaccharide-induced neuroinflammation in mice model

Liu, X., Meng, P., Liu, Z., Tian, X., Xi, J., Du, M., Yang, H., & Long, Q. (2024) · Nanomedicine · doi:10.1080/17435889.2024.2422811 · Cited by 7 · see citing works

Neuroprotective Effects of Astrocyte Extracellular Vesicles in Stroke

Yakovlev, A. A. (2022) · Neurochemical Journal · doi:10.1134/s1819712422020143 · Cited by 7 · see citing works

Microfluidic nanomagnetically isolated neuron- and astrocyte-derived extracellular vesicles to differentiate Lewy body and Alzheimer’s disease

Yang, S. J., Lin, A. A., Shen, H., Pappalardo, L. W., Spychalski, G. B., Rosario, J. G., Forsberg, L. K., Grant, K. M., Buser, J. R., Savica, R., et al. (2026) · npj Biosensing · doi:10.1038/s44328-026-00086-x · Cited by 6 · see citing works

Single step capture and assessment of multiple plasma extracellular vesicle biomarkers in Alzheimer's disease detection

Lewis, J. M., Harris, D.-A., Kosmatka, J., Mikrut, E., Evenson, J., Balcer, H. I., Dhani, H., Hinestrosa, J. P., Rissman, R. A., & Billings, P. R. (2024) · Journal of Alzheimer s Disease · doi:10.1177/13872877241291964 · Cited by 6 · see citing works

Astrocyte Dysfunction Reflected in Ischemia-Induced Astrocyte-Derived Extracellular Vesicles: A Pilot Study on Acute Ischemic Stroke Patients

Forró, T., Manu, D. R., Barbu–Tudoran, L., & Bălașa, R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212471 · Cited by 6 · see citing works

The Potential Role of Exosomes in Communication Between Astrocytes and Endothelial Cells

Czpakowska, J., Glabinski, A. R., & Szpakowski, P. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26104676 · Cited by 7 · see citing works

Understanding the Intricate Role of Exosomes in Pathogenesis of Alzheimer’s Disease

Chauhan, S., Behl, T., Sehgal, A., Singh, S., Sharma, N., Gupta, S., Albratty, M., Najmi, A., Meraya, A. M., & Alhazmi, H. A. (2022) · Neurotoxicity Research · doi:10.1007/s12640-022-00621-4 · Cited by 6 · see citing works

Alteration of Neural Network and Hippocampal Slice Activation through Exosomes Derived from 5XFAD Nasal Lavage Fluid

Kim, S. S., Jeon, J. K., Ganbat, D., Kim, T.-W., Shin, K., Hong, S., & Hong, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814064 · Cited by 6 · see citing works

Synergism Between Hypothalamic Astrocytes and Neurons in Metabolic Control

Frago, L. M., Gómez-Romero, A., Collado‐Perez, R., Argente, J., & Chowen, J. A. (2024) · Physiology · doi:10.1152/physiol.00009.2024 · Cited by 5 · see citing works

Extracellular vesicles released by LPS-stimulated spinal organotypic slices spread neuroinflammation into naïve slices through connexin43 hemichannel opening and astrocyte aberrant calcium dynamics

Memo, C., Parisse, P., Amoriello, R., Pachetti, M., Palandri, A., Casalis, L., Ballerini, C., & Ballerini, L. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1433309 · Cited by 4 · see citing works

Gestational Diabetes Mellitus Rats Induce Anxiety-Depression-Like Behavior in Offspring: Association with Neuroinflammation and NF-κB Pathway

Han, J., Tan, X., Wei, Y., Hu, Z., Yang, Q., Zhu, Y., Chen, Z., Zhang, Y., Yu, H., Cai, X., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05033-x · Cited by 4 · see citing works

Protective effect of dexmedetomidine on neuronal hypoxic injury through inhibition of miR-134

Li, Y.-J., Zhang, D.-Z., Xi, Y., & Wu, C.-A. (2021) · Human & Experimental Toxicology · doi:10.1177/09603271211023784 · Cited by 4 · see citing works

A convenient model of serum-induced reactivity of human astrocytes to investigate astrocyte-derived extracellular vesicles

White, K. E., Bailey, H. L., Shaw, B., Geiszler, P. C., Mesquita-Ribeiro, R., Scott, D., Layfield, R., & Serres, S. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1414142 · Cited by 3 · see citing works

Extracellular Vesicles: A Promising Therapeutic Approach to Alzheimer's Disease

Mehrabadi, S. (2025) · Current Alzheimer Research · doi:10.2174/0115672050365314250112042136 · Cited by 3 · see citing works

Unpacking the role of exosomal proteins and nucleic acids in ischemic stroke: Insights from diverse cellular sources

Su, Y. Y. T., Du, F., & Liu, J. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.147081 · Cited by 3 · see citing works

Interpreting the rich dialogue between astrocytes and neurons: An overview in Rett syndrome

Postogna, F. M., Roggero, O. M., Biella, F., & Frasca, A. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111386 · Cited by 4 · see citing works

AstroGreen transgenic mouse illuminates the trafficking of astrocyte-derived extracellular vesicles

Nieland, L., Haidar, E. A., Rufino‐Ramos, D., Prabhakar, S., Samaha, Y., Breyne, K., Fordjour, F. K., Das, S., Broekman, M. L. D., Gould, S. J., et al. (2025) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2025.104051 · Cited by 3 · see citing works

Protein profiling of extracellular vesicles from iPSC-derived astrocytes of patients with ALS/PDC in Kii peninsula

Kobayashi, H., Ueda, K., Morimoto, S., Ishikawa, M., Leventoux, N., Sasaki, R., HIROKAWA, Y. S., Kokubo, Y., & Okano, H. (2023) · Neurological Sciences · doi:10.1007/s10072-023-07000-7 · Cited by 3 · see citing works

On Multicell-Interaction Chip: In Situ Observing the Interactions between the Astrocytes with Lysosomal Dysfunction and BBB Cells

Zhao, Y., Zhang, C., Liang, C., Lv, X., Zhou, D., Deng, Y., & Zhang, R. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c04893 · Cited by 2 · see citing works

Atypical antipsychotics alter microglial functions via astrocyte-derived extracellular vesicles

Yeh, H., Song, Y., Bowen, J. J., McCrea, L. T., Sheridan, S. D., & Perlis, R. H. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.106132 · Cited by 2 · see citing works

Extracellular vesicles: A new therapeutic drug for nerve injury repair

Cai, J., Ren, C., Wang, C., Shen, S., Xu, B., & Cui, C. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-25-00133 · Cited by 4 · see citing works

Extracellular vesicles in molecular crosstalk and disease pathogenesis: a comprehensive review on mechanisms and therapeutic prospects

Balachandran, S., Arumugam, M. K., Kandy, R. R. K., Boopathy, L. K., Gopal, T., Rajamanickam, R., Rasineni, K., & Kharbanda, K. K. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.118186 · Cited by 2 · see citing works

Neuropathological and functional impact of astrocyte-derived extracellular vesicles in an aged model of Alzheimer's disease

Quach, B., Salehi, S. N., Roufegarinejad, R., Guleria, V. S., Mante, M., Florio, J. B., Rissman, R. A., & Winston, C. N. (2026) · Experimental Neurology · doi:10.1016/j.expneurol.2026.115893 · Cited by 2 · see citing works

Alkaline loading of extracellular vesicles produced from human neural stem cell-derived neurospheres enables CNS drug delivery

Singh, A. M., White, C. M., Phillips, A., Crowe, L. P., Marti, R., Finnerty, M. C., Viana, M. P., Antoniades, W., Bartlett, M. G., Martinez, V., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-58290-8 · Cited by 2 · see citing works

Astrocyte-derived extracellular vesicle phosphorylated TDP-43 as a blood-based biomarker for amyotrophic lateral sclerosis

Butt, T. H., Strait, M., Marcinczyk, L., Katz, G., Kalia, V., Jaafar, C., Saxena, R., Divjan, A., Saglimbeni, B., Umanes, M. E. M., et al. (2026) · Neurobiology of Disease · doi:10.1016/j.nbd.2026.107601 · Cited by 1 · see citing works

Acute Genetic Damage Induced by Ethanol and Corticosterone Seems to Modulate Hippocampal Astrocyte Signaling

Reyes-Ábalos, A. L., Álvarez-Zabaleta, M., Olivera‐Bravo, S., & Tomaso, M. V. D. (2024) · International Journal of Cell Biology · doi:10.1155/2024/5524487 · Cited by 1 · see citing works

An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole bloodPreprint

Rodriguez, B. V., Wen, Y., Shirk, E. N., Vazquez, S., Gololobova, O. A., Maxwell, A., Plunkard, J. C. M., Castell, N., Carlson, B. W., Queen, S. E., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.11.540421

Additional file 1 of Oxygen glucose deprivation-pretreated astrocyte-derived exosomes attenuates intracerebral hemorrhage (ICH)-induced BBB disruption through miR-27a-3p /ARHGAP25/Wnt/β-catenin axis

Hou, Y., Xie, Y., Liu, X., Chen, Y., Zhou, F., & Yang, B. (2024) · Figshare · doi:10.6084/m9.figshare.26669778

Astrocyte-derived extracellular vesicles as antigen-specific therapy for neuromyelitis optica spectrum disorder in the mouse modelPreprint

Naziri, H., Azizi, G., Ćirić, B., Zhang, G., & Rostami, A. M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.24.696382

Ultrasound‐enhanced delivery of donepezil and poly (β‐amino ester) nanoparticles via astrocyte‐derived exosomes in promoting amyloid‐β clearance and supporting neuronal regeneration

Li, X., Di, B., Niu, J., & Hou, H. (2026) · Journal of the Chinese Chemical Society · doi:10.1002/jccs.70132

Recent advances in the application of engineered extracellular vesicles from mesenchymal stem cells for traumatic central nervous system

Ahmadi, M., Saranjam, A., Hamidifar, M., Shoaran, M., & Rezaie, J. (2026) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2026.178536

Targeted isolation of astrocyte-derived extracellular vesicles using peptide-imprinted nanocomposites for neurological diagnostics

Lee, H. J., Roh, Y., Dao, T. N. T., Kim, J., Shin, W., Seo, D., Koo, B., Lee, E., & Shin, Y. (2026) · Nano Today · doi:10.1016/j.nantod.2026.103001

Amyloid precursor protein derivatives differentially alter the microRNA cargo of astrocyte-derived extracellular vesicles

Chu, A. J., Erlandsson, A., & Williams, J. M. (2026) · Neuroscience · doi:10.1016/j.neuroscience.2026.03.036

Identification du rôle des vésicules extracellulaires d’origine astrocytaire au cours de la transmission synaptique et de la plasticité synaptique à long terme

Hekking, R. (2024) · doi:10.70675/b21c4643z064az4200zadeaz4f800c84c3a7

Extracellular Vesicles in Stroke: Drivers of Brain–Body Network Crosstalk

Xu, Z. Y., Yu-Jia, J., Zhang, W., Ye, X.-H., & Gao, F. (2026) · Translational Stroke Research · doi:10.1007/s12975-026-01452-7

Deep learning segmentation with curvature consistency reveals astrocyte nanostructure across species

Fok, A. H. K., Wang, Y., Ng, M., Syed, T. A., Wong, T. L. H., Salmon, C. K., Salathiel, T., Grondin-Eddy, W., Fan, L., Kaleem Siddiqi, A., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117725

MgSO4 alleviates anxiety-like behaviours in mice after traumatic brain injury by inhibiting astrocytic TRPM7 in the amygdala

Xi, H., Miao, H., Zhao, N.-H., Liu, Y.-F., & Xue, L.-X. (2026) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2026.09.021

Astrocyte-Derived Extracellular Vesicles and the Evolution of Neural Complexity: Perspectives on Vesicle-Mediated Neuron–Glia Communication

Ciuba, K. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06214-y

Extracellular vesicles and Alzheimer’s disease: hotspots, trends, and future directions—a tri-database bibliometric analysis

Wang, X., & Zhang, B.-W. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1951959

Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders

Upadhya, R., Zingg, W., Shetty, S., & Shetty, A. K. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.04.017 · Cited by 282 · see citing works

Emerging Role of Astrocyte-Derived Extracellular Vesicles as Active Participants in CNS Neuroimmune Responses

Sutter, P. A., Lavoie, E. R., Lombardo, E. T., Pinter, M. K., & Crocker, S. J. (2023) · Immunological Investigations · doi:10.1080/08820139.2023.2281621 · Cited by 5 · see citing works

Research progress on astrocyte-derived extracellular vesicles in the pathogenesis and treatment of neurodegenerative diseases

Zhu, Y., Wang, F., Xia, Y., Wang, L., Lin, H., Zhong, T., & Wang, X. (2024) · Reviews in the Neurosciences · doi:10.1515/revneuro-2024-0043 · Cited by 15 · see citing works

Recent Advances on Extracellular Vesicles in Central Nervous System Diseases

Jin, T., Gu, J., Li, Z., Xu, Z., & Gui, Y. (2021) · Clinical Interventions in Aging · doi:10.2147/cia.s288415 · Cited by 44 · see citing works

Extracellular Vesicles: The Next Generation of Biomarkers and Treatment for Central Nervous System Diseases

Zanirati, G., dos Santos, P. G., Alcará, A. M., Bruzzo, F. T. K., Ghilardi, I. M., Wietholter, V., Xavier, F. A. C., Gonçalves, J. I. B., Marinowic, D. R., Shetty, A. K., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137371 · Cited by 46 · see citing works