Comorbid elevated symptoms of anxiety and depression in adults with type 1 or type 2 diabetes: Results from the International Diabetes MILES Study
Open accessAbstract
Aims We examined: (a) the prevalence of comorbid elevated symptoms of anxiety/depression; (b) its demographic/clinical correlates; (c) associations with self-care behaviors, by diabetes type. Methods Cross-sectional self-report data of 6590 adults with diabetes (42% type 1; 58% type 2) from the Australian and Dutch Diabetes MILES studies were used. Elevated symptoms of anxiety/depression were defined as GAD-7 ≥ 10/PHQ-9 ≥ 10. Results In both diabetes types, comorbid elevated symptoms of anxiety/depression were present in 9% and symptoms of anxiety alone in 2%; symptoms of depression alone were present in 8% of adults with type 1 diabetes and 11% with type 2 diabetes. Shorter diabetes duration (type 1 only) was the only characteristic that distinguished those with comorbid elevated symptoms of anxiety/depression but not those with symptoms of anxiety/depression alone from the reference group (no/minimal symptoms of anxiety/depression). Those with comorbid elevated symptoms of anxiety/depression had increased odds of sub-optimal diabetes self-care behaviors compared with the reference group, with higher odds than those with symptoms of anxiety or depression alone. Conclusions Comorbid elevated symptoms of anxiety/depression affected one in ten respondents, who also had increased odds of suboptimal diabetes self-care. Those with shorter type 1 diabetes duration may be at increased risk.
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The association between generalized anxiety and suboptimal blood glucose levels is less clear.
“The association between generalized anxiety and suboptimal blood glucose levels is less clear (177,178).”
From The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (2021) · cites this paper as [178]
The available passages labeled Abstract contain bibliographic information but no findings about blood glucose levels. Searches for generalized anxiety, glycemic control, and HbA1c found no passage addressing whether that association is unclear. (LLM, conf=0.72)
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Мардиев, О., & Khayatov, R. B. (2023) · Eurasian Journal of Medical and Natural Sciences · doi:10.70413/ejmns-v03-i08-s9704
- Authors
- Nefs, G., Hendrieckx, C., Reddy, P., Browne, J. L., Bot, M., Dixon, J., Kyrios, M., Speight, J., & Pouwer, F.
- Affiliations
- Tilburg University (NL)
- Deakin University (AU)
- University of Technology Sydney (AU)
- Amsterdam Public Health (NL)
- Baker Heart and Diabetes Institute (AU)
- Flinders University (AU)
- Corresponding author
- Nefs, Giesje
- ORCID
- Venue
- Journal of Diabetes and its Complications
- Publisher
- Elsevier BV
- Published
- 2019-08
- Volume
- 33
- Issue
- 8
- Pages
- 523-529
- ISSN
- 0891-6632 (ISSN-L)
- 1056-8727
- OpenAlex
- W2940824667
- Cited by
- 56
- References
- 36
- Citations by year
- 2026: 6 · 2025: 3 · 2024: 6 · 2023: 4 · 2022: 16 · 2021: 9 · 2020: 10 · 2019: 2
- FWCI
- 7.51
- Type
- journal article
- Language
- en
- Open access
- green
- pure.amsterdamumc.nl
- Licence
- Locations
- Journal of Diabetes and its Complications (publishedVersion)
- Research portal (Tilburg University) (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion, other-oa)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- UTS ePRESS (University of Technology Sydney) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Swinburne figshare (Swinburne University of Technology) (submittedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion, cc-by-nc-nd)
- Funders
- National Diabetes Services Scheme
- sanofi-aventis
- Dutch Association for Diabetes Research
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- anxiety, depression, comorbidities, type 1 diabetes, type 2 diabetes, diabetes self-care, diabetes duration, prevalence, GAD-7, PHQ-9, mental health in diabetes
- MeSH terms
- Adult, Anxiety, Australia, Cross-Sectional Studies, Depression, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Humans, Male, Middle Aged, Netherlands, Surveys and Questionnaires, Self Care, Comorbidity, Self Report
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