Cited by 56Diabetes Management and EducationDiabetes Management and ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Comorbid elevated symptoms of anxiety and depression in adults with type 1 or type 2 diabetes: Results from the International Diabetes MILES Study

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Nefs, Giesje, Hendrieckx, Christel, Reddy, Prasuna, Browne, Jessica L., Bot, Mariska, Dixon, John, Kyrios, Michael, Speight, Jane +1 more·2019·Journal of Diabetes and its Complications

Abstract

Aims We examined: (a) the prevalence of comorbid elevated symptoms of anxiety/depression; (b) its demographic/clinical correlates; (c) associations with self-care behaviors, by diabetes type. Methods Cross-sectional self-report data of 6590 adults with diabetes (42% type 1; 58% type 2) from the Australian and Dutch Diabetes MILES studies were used. Elevated symptoms of anxiety/depression were defined as GAD-7 ≥ 10/PHQ-9 ≥ 10. Results In both diabetes types, comorbid elevated symptoms of anxiety/depression were present in 9% and symptoms of anxiety alone in 2%; symptoms of depression alone were present in 8% of adults with type 1 diabetes and 11% with type 2 diabetes. Shorter diabetes duration (type 1 only) was the only characteristic that distinguished those with comorbid elevated symptoms of anxiety/depression but not those with symptoms of anxiety/depression alone from the reference group (no/minimal symptoms of anxiety/depression). Those with comorbid elevated symptoms of anxiety/depression had increased odds of sub-optimal diabetes self-care behaviors compared with the reference group, with higher odds than those with symptoms of anxiety or depression alone. Conclusions Comorbid elevated symptoms of anxiety/depression affected one in ten respondents, who also had increased odds of suboptimal diabetes self-care. Those with shorter type 1 diabetes duration may be at increased risk.

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Authors
Nefs, G., Hendrieckx, C., Reddy, P., Browne, J. L., Bot, M., Dixon, J., Kyrios, M., Speight, J., & Pouwer, F.
Affiliations
  • Tilburg University (NL)
  • Deakin University (AU)
  • University of Technology Sydney (AU)
  • Amsterdam Public Health (NL)
  • Baker Heart and Diabetes Institute (AU)
  • Flinders University (AU)
Corresponding author
Nefs, Giesje
Venue
Journal of Diabetes and its Complications
Publisher
Elsevier BV
Published
2019-08
Volume
33
Issue
8
Pages
523-529
ISSN
  • 0891-6632 (ISSN-L)
  • 1056-8727
OpenAlex
W2940824667
Cited by
56
References
36
Citations by year
2026: 6 · 2025: 3 · 2024: 6 · 2023: 4 · 2022: 16 · 2021: 9 · 2020: 10 · 2019: 2
FWCI
7.51
Type
journal article
Language
en
Open access
Locations
  • Journal of Diabetes and its Complications (publishedVersion)
  • Research portal (Tilburg University) (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion, other-oa)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Figshare (submittedVersion, cc-by)
  • UTS ePRESS (University of Technology Sydney) (submittedVersion)
  • Radboud Repository (Radboud University) (submittedVersion)
  • Swinburne figshare (Swinburne University of Technology) (submittedVersion)
  • University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion, cc-by-nc-nd)
Funders
  • National Diabetes Services Scheme
  • sanofi-aventis
  • Dutch Association for Diabetes Research
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
anxiety, depression, comorbidities, type 1 diabetes, type 2 diabetes, diabetes self-care, diabetes duration, prevalence, GAD-7, PHQ-9, mental health in diabetes
MeSH terms
Adult, Anxiety, Australia, Cross-Sectional Studies, Depression, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Humans, Male, Middle Aged, Netherlands, Surveys and Questionnaires, Self Care, Comorbidity, Self Report

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