Web-Based Depression Treatment for Type 1 and Type 2 Diabetic Patients
Open accessAbstract
OBJECTIVE: Comorbid depression is common in patients with type 1 and type 2 diabetes, adversely affecting quality of life, diabetes outcomes, and mortality. Depression can be effectively treated with cognitive behavior therapy (CBT). The Internet is a new and attractive method for delivering CBT intervention on a large scale at relatively low costs. This study evaluated the effectiveness of Web-based CBT for depression treatment in adults with type 1 or type 2 diabetes, with minimal guidance. RESEARCH DESIGN AND METHODS: A randomized controlled trial was conducted in the Netherlands in 255 adult diabetic patients with elevated depressive symptoms. Primary outcomes were depressive symptoms. Secondary outcomes were diabetes-specific emotional distress and glycemic control. Assessments were at baseline, after treatment, and at the 1-month follow-up. RESULTS: The Web-based CBT was effective in reducing depressive symptoms by intention-to-treat analyses (P = 0.04, d = 0.29; clinical improvement 41% vs. 24% P < 0.001) and by per-protocol analyses (P < 0.001, d = 0.70; clinical improvement, 56% vs. 24% P < 0.001). The intervention reduced diabetes-specific emotional distress (P = 0.03) but had no beneficial effect on glycemic control (P > 0.05). CONCLUSIONS: Web-based CBT depression treatment is effective in reducing depressive symptoms in adults with type 1 and type 2 diabetes. In addition, the intervention reduces diabetes-specific emotional distress in depressed patients.
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CBT-based online support for adults with type 1 and type 2 diabetes who have depression was effective in reducing diabetes-related emotional stress.
“The intervention was effective in reducing depressive symptoms and diabetes-related emotional stress. However, no effect on metabolic control was observed.13”
From Acceptance and commitment therapy (ACT) for adult type 1 diabetes management: Study protocol for a randomised controlled trial (2018) · cites this paper as [13]
CBT-based online support for adults with type 1 and type 2 diabetes who have depression was effective in reducing depressive symptoms.
“The intervention was effective in reducing depressive symptoms and diabetes-related emotional stress. However, no effect on metabolic control was observed.13”
From Acceptance and commitment therapy (ACT) for adult type 1 diabetes management: Study protocol for a randomised controlled trial (2018) · cites this paper as [13]
CBT-based online support for adults with type 1 and type 2 diabetes who have depression had no effect on metabolic control.
“The intervention was effective in reducing depressive symptoms and diabetes-related emotional stress. However, no effect on metabolic control was observed.13”
From Acceptance and commitment therapy (ACT) for adult type 1 diabetes management: Study protocol for a randomised controlled trial (2018) · cites this paper as [13]
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“…depressive symptoms in patients with diabetes, such as cognitive behavior therapy (CBT; Gonzalez et al. 2010; Lamers et al. 2010; Lustman et al. 1998; Penckofer et al. 2012; van Bastelaar et al. 2011) and mindfulness-based cognitive therapy (MBCT; Schroevers et al. 2013; van Son et al. 2013).”
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- Authors
- van Bastelaar, K. M. P., Pouwer, F., Cuijpers, P., Riper, H., & Snoek, F. J.
- Affiliations
- Department of Medical Psychology, VU University Medical Center, Amsterdam, the Netherlands
- Department of Medical Psychology & Neuropsychology, Center of Research on Psychology in Somatic diseases (CoRPS), Tilburg University, Tilburg, the Netherlands
- Amsterdam Public Health (NL)
- Trimbos Institute (NL)
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2011-01-20
- Volume
- 34
- Issue
- 2
- Pages
- 320-325
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- PMC
- PMC3024341
- OpenAlex
- W2152049259
- Cited by
- 209
- References
- 26
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 9 · 2023: 8 · 2022: 16 · 2021: 12 · 2020: 16 · 2019: 10 · 2018: 16 · 2017: 13 · 2016: 16 · 2015: 25 · 2014: 14 · 2013: 17 · 2012: 20
- FWCI
- 24.81
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Diabetes Care (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- Research portal (Tilburg University) (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- VU Research Portal (publishedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Multilingual Matters (Channel View Publications) (submittedVersion, cc-by-nc-nd)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- depression, type 1 diabetes, type 2 diabetes, online intervention, depressive symptoms, glycemic control, diabetes comorbidity
- MeSH terms
- Adult, Affective Symptoms, Depression, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Follow-Up Studies, Humans, Male, Middle Aged, Psychotherapy, Comorbidity, Treatment Outcome, Telemedicine, Internet
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