Cited by 209Digital Mental Health InterventionsDiabetes Management and EducationAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Web-Based Depression Treatment for Type 1 and Type 2 Diabetic Patients

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van Bastelaar, Kim M.P., Pouwer, François, Cuijpers, Pim, Riper, Heleen, Snoek, Frank J.·2011·Diabetes Care

Abstract

OBJECTIVE: Comorbid depression is common in patients with type 1 and type 2 diabetes, adversely affecting quality of life, diabetes outcomes, and mortality. Depression can be effectively treated with cognitive behavior therapy (CBT). The Internet is a new and attractive method for delivering CBT intervention on a large scale at relatively low costs. This study evaluated the effectiveness of Web-based CBT for depression treatment in adults with type 1 or type 2 diabetes, with minimal guidance. RESEARCH DESIGN AND METHODS: A randomized controlled trial was conducted in the Netherlands in 255 adult diabetic patients with elevated depressive symptoms. Primary outcomes were depressive symptoms. Secondary outcomes were diabetes-specific emotional distress and glycemic control. Assessments were at baseline, after treatment, and at the 1-month follow-up. RESULTS: The Web-based CBT was effective in reducing depressive symptoms by intention-to-treat analyses (P = 0.04, d = 0.29; clinical improvement 41% vs. 24% P < 0.001) and by per-protocol analyses (P < 0.001, d = 0.70; clinical improvement, 56% vs. 24% P < 0.001). The intervention reduced diabetes-specific emotional distress (P = 0.03) but had no beneficial effect on glycemic control (P > 0.05). CONCLUSIONS: Web-based CBT depression treatment is effective in reducing depressive symptoms in adults with type 1 and type 2 diabetes. In addition, the intervention reduces diabetes-specific emotional distress in depressed patients.

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Authors
van Bastelaar, K. M. P., Pouwer, F., Cuijpers, P., Riper, H., & Snoek, F. J.
Affiliations
  • Department of Medical Psychology, VU University Medical Center, Amsterdam, the Netherlands
  • Department of Medical Psychology & Neuropsychology, Center of Research on Psychology in Somatic diseases (CoRPS), Tilburg University, Tilburg, the Netherlands
  • Amsterdam Public Health (NL)
  • Trimbos Institute (NL)
Venue
Diabetes Care
Published
2011-01-20
Volume
34
Issue
2
Pages
320-325
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
OpenAlex
W2152049259
Cited by
209
References
26
Citations by year
2026: 5 · 2025: 5 · 2024: 9 · 2023: 8 · 2022: 16 · 2021: 12 · 2020: 16 · 2019: 10 · 2018: 16 · 2017: 13 · 2016: 16 · 2015: 25 · 2014: 14 · 2013: 17 · 2012: 20
FWCI
24.81
Type
journal article
Language
en
Open access
Locations
  • Diabetes Care (publishedVersion, cc-by-nc-nd)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • Research portal (Tilburg University) (publishedVersion)
  • PubMed (publishedVersion)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
  • VU Research Portal (publishedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Pure Amsterdam UMC (submittedVersion)
  • Multilingual Matters (Channel View Publications) (submittedVersion, cc-by-nc-nd)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
depression, type 1 diabetes, type 2 diabetes, online intervention, depressive symptoms, glycemic control, diabetes comorbidity
MeSH terms
Adult, Affective Symptoms, Depression, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Follow-Up Studies, Humans, Male, Middle Aged, Psychotherapy, Comorbidity, Treatment Outcome, Telemedicine, Internet

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