Cited by 93Thyroid Disorders and TreatmentsPotassium and Related DisordersThyroid and Parathyroid Surgery

The pitfalls of potassium replacement in thyrotoxic periodic paralysis: a case report and review of the literature

Tassone, Heather, Moulin, Aimee, Henderson, Sean O·2004·The Journal of Emergency Medicine

Abstract

Thyrotoxic Periodic Paralysis is an uncommon disorder seen primarily in Asian males and caused by excessive thyroid hormones. This is an endocrine emergency that can lead to respiratory failure, dysrhythmia, and death. The mainstay of therapy has been potassium replacement, however, recent evidence suggests propranolol is a more effective therapy. We present a severe case of TPP in a 22-year-old Latino male with rapidly progressive ascending paralysis and hypokalemia severe enough to lead to cardiac arrest.

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Crossref · 10.1016/j.jemermed.2003.05.004

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40 of 40 references verified0 citation errors · 0 not checkable

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  • There may be a delayed response of a few hours following potassium administration in TPP.

    “There may be a delayed response of a few hours following potassium administration [44].”

    From Thyrotoxic Periodic Paralysis: Clinical Challenges (2014) · cites this paper as [44]

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Authors
Tassone, H., Moulin, A., & Henderson, S. O.
Affiliations
University of Southern California (US)
Corresponding author
Henderson, Sean O
Venue
The Journal of Emergency Medicine
Publisher
Elsevier BV
Published
2004-02
Volume
26
Issue
2
Pages
157-161
ISSN
0736-4679 (ISSN-L)
OpenAlex
W2167214245
Cited by
93
References
40
Citations by year
2026: 2 · 2025: 2 · 2023: 2 · 2022: 7 · 2021: 4 · 2020: 4 · 2019: 2 · 2018: 5 · 2017: 1 · 2016: 4 · 2015: 4 · 2014: 13 · 2013: 3 · 2012: 5
FWCI
4.87
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Emergency Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Potassium and Related Disorders
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
Keywords
thyrotoxic periodic paralysis, potassium supplementation, hypokalemia, propranolol, hyperthyroidism, ascending paralysis, cardiac arrest, endocrine emergencies
MeSH terms
Adult, Anti-Arrhythmia Agents, Emergency Medical Services, Humans, Hyperkalemia, Hyperthyroidism, Infusions, Intravenous, Male, Potassium, Propranolol, Thyrotoxicosis, Treatment Outcome, Tachycardia, Ventricular, Hypokalemic Periodic Paralysis

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