Magnoflorine Prevent the Skeletal Muscle Atrophy Via Akt/mTOR/FoxO Signal Pathway and Increase Slow-MyHC Production in Streptozotocin-Induced Diabetic Rats

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

Ohkawa, H., Ohishi, N., & Yagi, K. (1979) · Analytical Biochemistry · doi:10.1016/0003-2697(79)90738-3 · Cited by 29,460 · see citing works

Selenium: Biochemical Role as a Component of Glutathione Peroxidase

Rotruck, J. T., Pope, A. L., Ganther, H. E., Swanson, A. B., Hafeman, D. G., & Hoekstra, W. G. (1973) · Science · doi:10.1126/science.179.4073.588 · Cited by 7,815 · see citing works

Colorimetric assay of catalase

Sinha, A. K. (1972) · Analytical Biochemistry · doi:10.1016/0003-2697(72)90132-7 · Cited by 5,574 · see citing works

First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid

Ighodaro, O. M., & Akinloye, O. A. (2017) · Alexandria Journal of Medicine · doi:10.1016/j.ajme.2017.09.001 · Cited by 3,970 · see citing works

The Loss of Skeletal Muscle Strength, Mass, and Quality in Older Adults: The Health, Aging and Body Composition Study

Goodpaster, B. H., Park, S. W., Harris, T. B., Kritchevsky, S. B., Nevitt, M., Schwartz, A. V., Simonsick, E. M., Tylavsky, F. A., Visser, M., Newman, A. B., et al. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.10.1059 · Cited by 3,083 · see citing works

Type 2 diabetes mellitus

DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, J. J., Hu, F. B., Kahn, C. R., Raz, I., Shulman, G. I., et al. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.19 · Cited by 2,611 · see citing works

Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase

Kono, Y. (1978) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(78)90479-4 · Cited by 1,787 · see citing works

The PI3K/AKT Pathway in Obesity and Type 2 Diabetes

Huang, X., Liu, G., Guo, J., & Su, Z. (2018) · International Journal of Biological Sciences · doi:10.7150/ijbs.27173 · Cited by 1,673 · see citing works

Mechanisms regulating skeletal muscle growth and atrophy

Schiaffino, S., Dyar, K. A., Ciciliot, S., Blaauw, B., & Sandri, M. (2013) · The FEBS Journal · doi:10.1111/febs.12253 · Cited by 1,492 · see citing works

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Lee, Y. S., Kim, W. S., Kim, K. H., Yoon, M. J., Cho, H. J., Shen, Y., Ye, J.-M., Lee, C. H., Oh, W. K., Kim, C. T., et al. (2006) · Diabetes · doi:10.2337/db06-0006 · Cited by 1,054 · see citing works

Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models

Schiaffino, S., & Mammucari, C. (2011) · Skeletal Muscle · doi:10.1186/2044-5040-1-4 · Cited by 816 · see citing works

Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes

Park, S. W., Goodpaster, B. H., Lee, J. S., Kuller, L. H., Boudreau, R., de Rekeneire, N., Harris, T. B., Kritchevsky, S., Tylavsky, F. A., Nevitt, M., et al. (2009) · Diabetes Care · doi:10.2337/dc09-0264 · Cited by 778 · see citing works

Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions

Du, J., Wang, X., Miereles, C., Bailey, J. L., Debigaré, R., Zheng, B., Price, S. R., & Mitch, W. E. (2004) · Journal of Clinical Investigation · doi:10.1172/jci18330 · Cited by 730 · see citing works

Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy

Milan, G., Romanello, V., Pescatore, F., Armani, A., Paik, J.-H., Frasson, L., Seydel, A., Zhao, J., Abraham, R., Goldberg, A. L., et al. (2015) · Nature Communications · doi:10.1038/ncomms7670 · Cited by 709 · see citing works

The pathogenesis and pathophysiology of type 1 and type 2 diabetes mellitus

Ozougwu, O. (2013) · Journal of Physiology and Pathophysiology · doi:10.5897/jpap2013.0001 · Cited by 654 · see citing works

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

Bernet, J. D., Doles, J. D., Hall, J. K., Kelly Tanaka, K., Carter, T. A., & Olwin, B. B. (2014) · Nature Medicine · doi:10.1038/nm.3465 · Cited by 573 · see citing works

Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension

Lan, J., Zhao, Y., Dong, F., Yan, Z., Zheng, W., Fan, J., & Sun, G. (2015) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2014.09.049 · Cited by 458 · see citing works

Role of Myokines in Regulating Skeletal Muscle Mass and Function

Lee, J. H., & Jun, H.-S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00042 · Cited by 432 · see citing works

The Role of Skeletal Muscle Glycogen Breakdown for Regulation of Insulin Sensitivity by Exercise

Jensen, J., Rustad, P. I., Kolnes, A. J., & Lai, Y.-C. (2011) · Frontiers in Physiology · doi:10.3389/fphys.2011.00112 · Cited by 412 · see citing works

Akt signalling through GSK‐3β, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy

Léger, B., Cartoni, R., Praz, M., Lamon, S., Dériaz, O., Crettenand, A., Gobelet, C., Rohmer, P., Konzelmann, M., Lüthi, F., et al. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.116715 · Cited by 381 · see citing works

Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) - validation of the Ayurvedic pharmacology through experimental and clinical studies

Upadhyay, A. K., Kumar, K., Kumar, A., & Mishra, H. S. (2010) · International Journal of Ayurveda Research · doi:10.4103/0974-7788.64405 · Cited by 369 · see citing works

Streptozotocin-nicotinamide-induced rat model of type 2 diabetes (review)

Ghasemi, A., Khalifi, S., & Jeddi, S. (2014) · Acta Physiologica Hungarica · doi:10.1556/aphysiol.101.2014.4.2 · Cited by 282 · see citing works

Muscle Atrophy Induced by Mechanical Unloading: Mechanisms and Potential Countermeasures

Gao, Y., Arfat, Y., Wang, H., & Goswami, N. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00235 · Cited by 275 · see citing works

The TWEAK–Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice

Mittal, A., Bhatnagar, S., Kumar, A., Lach-Trifilieff, E., Wauters, S., Li, H., Makonchuk, D. Y., Glass, D. J., & Kumar, A. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200909117 · Cited by 250 · see citing works

Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK

Cheng, Z., Pang, T., Gu, M., Gao, A., Xie, C., Li, J.-Y., Nan, F., & Li, J. X. (2006) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2006.09.007 · Cited by 240 · see citing works

Muscle atrophy in patients with Type 2 Diabetes Mellitus: roles of inflammatory pathways, physical activity and exercise.

Perry, B. D., Caldow, M. K., Brennan‐Speranza, T. C., Sbaraglia, M., Jerums, G., GARNHAM, A. P., Wong, C. Y., Levinger, P., Haq, M. A. U., Hare, D. L., et al. (2016) · PubMed · Cited by 239 · see citing works

Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy

Reed, S. A., Sandesara, P. B., Judge, S. M., & Judge, A. R. (2011) · The FASEB Journal · doi:10.1096/fj.11-189977 · Cited by 224 · see citing works

Myokines in insulin resistance and type 2 diabetes

Eckardt, K., Görgens, S. W., Raschke, S., & Eckel, J. (2014) · Diabetologia · doi:10.1007/s00125-014-3224-x · Cited by 223 · see citing works

Diabetic myopathy: impact of diabetes mellitus on skeletal muscle progenitor cells

D’Souza, D. M., Al‐Sajee, D., & Hawke, T. J. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00379 · Cited by 223 · see citing works

Role of Oxidative Stress as Key Regulator of Muscle Wasting during Cachexia

Ábrigo, J., Elorza, Á. A., Riedel, C. A., Vilos, C., Simón, F., Cabrera, D., Estrada, L. D., & Cabello‐Verrugio, C. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/2063179 · Cited by 221 · see citing works

Hypoglycemic activity of alkaloidal fraction of Tinospora cordifolia

Patel, M. B., & Mishra, S. (2011) · Phytomedicine · doi:10.1016/j.phymed.2011.05.006 · Cited by 220 · see citing works

Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to Suppress Th17 and Th1 T Cell Differentiation in Type 1 Diabetic Mice

Cui, G., Qin, X., Zhang, Y., Gong, Z., Ge, B., & Zang, Y. Q. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.012674 · Cited by 197 · see citing works

The ubiquitin-proteasome system and autophagy: Coordinated and independent activities

Cohen‐Kaplan, V., Livneh, I., Avni, N., Cohen-Rosenzweig, C., & Ciechanover, A. J. (2016) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2016.07.019 · Cited by 196 · see citing works

Mucopolysaccharide-degrading enzymes from the liver of the squid, Ommastrephes sloani pacificus I. Hyaluronidase

Kawai, Y., & Anno, K. (1971) · Biochimica et Biophysica Acta (BBA) - Enzymology · doi:10.1016/0005-2744(71)90234-8 · Cited by 183 · see citing works

Muscle dysfunction in type 2 diabetes: a major threat to patient’s mobility and independence

Bianchi, L., & Volpato, S. (2016) · Acta Diabetologica · doi:10.1007/s00592-016-0880-y · Cited by 175 · see citing works

Advanced glycation end‐products induce skeletal muscle atrophy and dysfunction in diabetic mice via a RAGE ‐mediated, AMPK ‐down‐regulated, Akt pathway

Chiu, C., Yang, R., Sheu, M., Chan, D., Yang, T., Tsai, K., Chiang, C., & Liu, S. (2015) · The Journal of Pathology · doi:10.1002/path.4674 · Cited by 161 · see citing works

Magnoflorine: A review of its pharmacology, pharmacokinetics and toxicity

Xu, T. C., Kuang, T., Du, H., Li, Q., Feng, T., Zhang, Y., & Fan, G. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104632 · Cited by 159 · see citing works

Increased Proteolysis, Myosin Depletion, and Atrophic AKT-FOXO Signaling in Human Diaphragm Disuse

Levine, S., Biswas, C., Dierov, J. K., Barsotti, R., Shrager, J. B., Nguyen, T., Sonnad, S. S., Kucharchzuk, J. C., Kaiser, L. R., Singhal, S. K., et al. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200910-1487oc · Cited by 157 · see citing works

Trim32 reduces PI3K–Akt–FoxO signaling in muscle atrophy by promoting plakoglobin–PI3K dissociation

Cohen, S., Lee, D., Zhai, B., Gygi, S. P., & Goldberg, A. L. (2014) · Journal of Cell Biology · doi:10.1083/jcb.201304167 · Cited by 103 · see citing works

Tumor necrosis factor alpha (TNF-α) inactivates the PI3-kinase/PKB pathway and induces atrophy and apoptosis in L6 myotubes

Sishi, B., & Engelbrecht, A. (2011) · Cytokine · doi:10.1016/j.cyto.2011.01.009 · Cited by 99 · see citing works

Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes

Perry, R. J., Peng, L., Cline, G. W., Wang, Y., Rabin-Court, A., Song, J. D., Zhang, D., Zhang, X., Nozaki, Y., Dufour, S., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.10.004 · Cited by 89 · see citing works

The Molecular Mechanisms of Calpains Action on Skeletal Muscle Atrophy

HUANG, J., & Zhu, X. (2016) · Physiological Research · doi:10.33549/physiolres.933087 · Cited by 84 · see citing works

Composition and Function of the Extracellular Matrix in the Human Body

Travascio, F. (2016) · InTech eBooks · doi:10.5772/61601 · Cited by 75 · see citing works

Apoptosis of pancreatic β-cells in Type 1 diabetes

Tomita, T. (2017) · Biomolecules and Biomedicine · doi:10.17305/bjbms.2017.1961 · Cited by 72 · see citing works

Advances in Chemistry and Bioactivity of Magnoflorine and Magnoflorine-Containing Extracts

Okoń, E., Kukula-Koch, W. A., Jarząb, A., Hałasa, M., Stepulak, A., & Wawruszak, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21041330 · Cited by 71 · see citing works

TNF-Like Weak Inducer of Apoptosis (TWEAK) Activates Proinflammatory Signaling Pathways and Gene Expression through the Activation of TGF-β-Activated Kinase 1

Kumar, M., Makonchuk, D. Y., Li, H., Mittal, A., & Kumar, A. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803357 · Cited by 70 · see citing works

Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation

Wilhelm, A., Shepherd, E. L., Amatucci, A., Munir, M., Reynolds, G. M., Humphreys, E. H., Resheq, Y. J., Adams, D., Hübscher, S. G., Burkly, L. C., et al. (2016) · The Journal of Pathology · doi:10.1002/path.4707 · Cited by 68 · see citing works

Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetes

Kruse, R., Vind, B. F., Petersson, S. J., Kristensen, J. M., & Højlund, K. (2015) · Diabetologia · doi:10.1007/s00125-015-3654-0 · Cited by 67 · see citing works

Calpain-dependent regulation of the skeletal muscle atrophy following unloading

Shenkman, B. S., Belova, S. P., Lomonosova, Y. N., Kostrominova, T. Y., & Nemirovskaya, T. L. (2015) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2015.07.011 · Cited by 62 · see citing works

Lack of caspase‐3 attenuates immobilization‐induced muscle atrophy and loss of tension generation along with mitigation of apoptosis and inflammation

Zhu, S., Nagashima, M., Khan, M. A. S., Yasuhara, S., Kaneki, M., & Martyn, J. A. J. (2012) · Muscle & Nerve · doi:10.1002/mus.23642 · Cited by 58 · see citing works

The Importance of Extracellular Matrix in Skeletal Muscle Development and Function

Grzelkowska‐Kowalczyk, K. (2016) · InTech eBooks · doi:10.5772/62230 · Cited by 52 · see citing works

Intact initiation of autophagy and mitochondrial fission by acute exercise in skeletal muscle of patients with Type 2 diabetes

Kruse, R., Pedersen, A. J. T., Kristensen, J. M., Petersson, S. J., Wojtaszewski, J. F. P., & Højlund, K. (2016) · Clinical Science · doi:10.1042/cs20160736 · Cited by 48 · see citing works

hmSOD1 gene mutation‐induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway

Hałoń, M., Borkowska, A., Kaczor, J. J., Ziółkowski, W., Flis, D. J., Knap, N., Kasperuk, K., & Antosiewicz, J. (2018) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12283 · Cited by 47 · see citing works

Magnoflorine Enhances LPS-Activated Pro-Inflammatory Responses via MyD88-Dependent Pathways in U937 Macrophages

Haque, M. A., Jantan, I., Harikrishnan, H., & Wahab, S. M. A. (2018) · Planta Medica · doi:10.1055/a-0637-9936 · Cited by 45 · see citing works

Inactivation of glycogen synthase kinase 3β (GSK-3β) enhances mitochondrial biogenesis during myogenesis

Theeuwes, W. F., Gosker, H. R., LANGEN, R. C. J., Pansters, N., Schols, A. M. W. J., & Remels, A. H. V. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.06.002 · Cited by 43 · see citing works

Protective Effects ofTinospora cordifoliaon Hepatic and Gastrointestinal Toxicity Induced by Chronic and Moderate Alcoholism

Sharma, B., & Dabur, R. (2015) · Alcohol and Alcoholism · doi:10.1093/alcalc/agv130 · Cited by 35 · see citing works

Tinospora Cordifolia Protects from Skeletal Muscle Atrophy by Alleviating Oxidative Stress and Inflammation Induced by Sciatic Denervation

Sharma, B., Dutt, V., Kaur, N., Mittal, A., & Dabur, R. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.112720 · Cited by 34 · see citing works

Moderate alcohol consumption in chronic form enhances the synthesis of cholesterol and C-21 steroid hormones, while treatment with Tinospora cordifolia modulate these events in men

Kumari, S., Mittal, A., & Dabur, R. (2016) · Steroids · doi:10.1016/j.steroids.2016.03.016 · Cited by 31 · see citing works

Dysregulation of muscle glycogen synthase in recovery from exercise in type 2 diabetes.

Pedersen, A. J. T., Hingst, J. R., Friedrichsen, M., Kristensen, J. M., Højlund, K., & Wojtaszewski, J. F. P. (2015) · Diabetologia · doi:10.1007/s00125-015-3582-z · Cited by 28 · see citing works

Magnoflorine from Coptis chinese has the potential to treat DNCB-induced Atopic dermatits by inhibiting apoptosis of keratinocyte

Wu, S., Yu, D., Liu, W., Zhang, J., Liu, X., Wang, J., Yu, M., Li, Z., Chen, Q., Li, X., et al. (2019) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2019.115093 · Cited by 28 · see citing works

Phytochemical composition changes in untreated stem juice of Tinospora cordifolia (W) Mier during refrigerated storage

Shirolkar, A. R., Gahlaut, A., Hooda, V., & Dabur, R. (2013) · Journal of Pharmacy Research · doi:10.1016/j.jopr.2013.01.018 · Cited by 21 · see citing works

Isoquinoline Alkaloids from Coptis Japonica Stimulate the Myoblast Differentiation Via P38 MAP-Kinase and Akt Signaling Pathway

Lee, H., Tuong, L. T., Jeong, J. H., Lee, S.-J., Bae, G.-U., & Ryu, J.-H. (2017) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2017.02.003 · Cited by 19 · see citing works

Rasayana effect of Guduchi Churna on the life span of Drosophila melanogaster

Pankaj, P., Vyas, M. K., Vyas, H., & Naria, M. (2016) · AYU (An International Quarterly Journal of Research in Ayurveda) · doi:10.4103/ayu.ayu_11_16 · Cited by 18 · see citing works

Effect of Pleurotus citrinopileatus on blood glucose, insulin and catalase of streptozotocin-induced type 2 diabetes mellitus rats.

Rushita, S., Vijayakumar, M., Noorlidah, A., Abdulla, M. A., & Sabaratnam, V. (2013) · The Journal of Animal and Plant Sciences · Cited by 17 · see citing works

Evaluation of metabolic and immunological changes in streptozotocin-nicotinamide induced diabetic rats

Mojani-Qomi, M. S., Sarmadi, V. H., Vellasamy, S., Sandrasaigaran, P., Rahmat, A. B., Peng, L. S., & Ramasamy, R. (2014) · Cellular Immunology · doi:10.1016/j.cellimm.2014.04.004 · Cited by 16 · see citing works

Guduchi Sawras (Tinospora cordifolia): An Ayurvedic drug treatment modulates the impaired lipid metabolism in alcoholics through dopaminergic neurotransmission and anti-oxidant defense system

Shirolkar, A. R., Sharma, B., Lata, S., & Dabur, R. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.08.051 · Cited by 16 · see citing works

Electrical Stimulation Based on Chronaxie Increases Fibrosis and Modulates TWEAK/Fn14, TGF-β/Myostatin, and MMP Pathways in Denervated Muscles

Pinheiro-Dardis, C. M., & Russo, T. L. (2016) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000000601 · Cited by 10 · see citing works

Tinospora cordifolia (Willd.) Miers ex Hook.f. & Thoms.- plant tissue culture and comparative chemo-profiling study as a function of different supporting trees

Bhalerao, B. M., Vishwakarma, K. S., & Maheshwari, V. L. (2013) · Cited by 9 · see citing works

Photobiomodulation therapy in diabetic wound healing

Ponnusamy, S., Mosca, R. C., Desai, K. M., & Arany, P. R. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816413-6.00015-0 · Cited by 5 · see citing works

Administration of Fresh Juice of Tinospora cordifolia Decreases Levels of Urinary Markers of Peroxisome Proliferator-Activated Receptors in Hyperlipidemic Patients

Shirolkar, A. R., & Dabur, R. (2016) · Indian Journal of Pharmaceutical Education and Research · doi:10.5530/ijper.50.3.19 · Cited by 2 · see citing works

Type 2 Diabetes Mellitus

Bhansali, A. K., & Gogate, Y. (2015) · Springer eBooks · doi:10.1007/978-81-322-2398-6_17 · Cited by 1 · see citing works

Sarcopenia, a condition shared by various diseases: can we alleviate or delay the progression?

Tarantino, G., Sinatti, G., Citro, V., Santini, S. J., & Balsano, C. (2023) · Internal and Emergency Medicine · doi:10.1007/s11739-023-03339-z · Cited by 104 · see citing works

Diabetic Muscular Atrophy: Molecular Mechanisms and Promising Therapies

Shen, Y., Li, M., Wang, K., Qi, G., Liu, H., Wang, W., Ji, Y., Chang, M., Deng, C., Xu, F., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.917113 · Cited by 103 · see citing works

Tinospora cordifolia (Willd.) Miers: Protection mechanisms and strategies against oxidative stress-related diseases

Arunachalam, K., Yang, X., & San, T. T. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114540 · Cited by 82 · see citing works

Berberis dictyophylla F. inhibits angiogenesis and apoptosis of diabetic retinopathy via suppressing HIF-1α/VEGF/DLL-4/Notch-1 pathway

Ai, X., Yu, P., Luo, L., Sun, J., Tao, H., Wang, X., & Meng, X. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115453 · Cited by 65 · see citing works

Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy

Wang, Y., Liu, Q., Quan, H., Kang, S.-G., Huang, K., & Tong, T. (2021) · Nutrients · doi:10.3390/nu13061914 · Cited by 61 · see citing works

Natural Aporphine Alkaloids with Potential to Impact Metabolic Syndrome

Wang, F., Zhu, N., Zhou, F., & Lin, D.-X. (2021) · Molecules · doi:10.3390/molecules26206117 · Cited by 52 · see citing works

The Multiple Roles of Lactate in the Skeletal Muscle

Bartoloni, B., Mannelli, M., Gamberi, T., & Fiaschi, T. (2024) · Cells · doi:10.3390/cells13141177 · Cited by 51 · see citing works

Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy.

Yadav, A., Yadav, S., Singh, S., & Dabur, R. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.174995 · Cited by 45 · see citing works

Skeletal muscle atrophy after sciatic nerve damage: Mechanistic insights

Yadav, A., & Dabur, R. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176506 · Cited by 38 · see citing works

Molecular mechanisms of skeletal muscle atrophy: clinical challenges and future therapeutic strategies

Gong, J., Yao, X., Shang, T., Li, X., Chen, B., & Sun, H. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.117913 · Cited by 35 · see citing works

Fermented ginseng leaf enriched with rare ginsenosides relieves exercise-induced fatigue via regulating metabolites of muscular interstitial fluid, satellite cells-mediated muscle repair and gut microbiota

Zheng, Z.-Y., Xie, G., Liu, H., Tan, G., Li, L., Liu, W., & Li, M. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104509 · Cited by 22 · see citing works

The role and mechanisms of myokines in sarcopenia: new intervention strategies for the challenges of aging

Cui, X., Liu, H., Liu, Y., Yu, Z., Wang, D., Wei, W., & Wang, S. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1665708 · Cited by 22 · see citing works

Magnoflorine Attenuates Cerebral Ischemia-Induced Neuronal Injury via Autophagy/Sirt1/AMPK Signaling Pathway

Liang, H., Chang, X., Xia, R., Wei, W., Guo, H., & Yang, M. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/2131561 · Cited by 21 · see citing works

Simiao Wan and its ingredients alleviate type 2 diabetes mellitus via IRS1/AKT2/FOXO1/GLUT2 signaling

Xia, T., Xu, W.-J., Hu, Y., Luo, Z., He, W., Liu, C., & Tan, X. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1012961 · Cited by 18 · see citing works

Bitter yet beneficial: The dual role of dietary alkaloids in managing diabetes and enhancing cognitive function

Alkanad, M. A., Hani, U., Annegowda, H. V., Ghazwani, M., Haider, N., Osmani, R. A. M., Pandareesh, M. D., Hamsalakshmi, & Bhat, R. (2024) · BioFactors · doi:10.1002/biof.2034 · Cited by 17 · see citing works

Epigenetics of Skeletal Muscle Atrophy

Du, J., Wu, Q., & Bae, E. J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158362 · Cited by 15 · see citing works

Administration of tauroursodeoxycholic acid attenuates dexamethasone-induced skeletal muscle atrophy

Chen, H., Ma, J., & Ma, X. (2021) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2021.06.102 · Cited by 14 · see citing works

Diabetes-induced muscle wasting: molecular mechanisms and promising therapeutic targets

Qiao, R., Guo, J., Zhang, C., Wang, S., Fang, J., Geng, R., Kang, S., Huang, K., & Tong, T. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2024.2382348 · Cited by 13 · see citing works

Alkaloids as Promising Agents for the Management of Insulin Resistance: A Review

Amssayef, A., & Eddouks, M. (2023) · Current Pharmaceutical Design · doi:10.2174/0113816128270340231121043038 · Cited by 12 · see citing works

The Therapeutic Potential of Four Main Compounds of Zanthoxylum nitidum (Roxb.) DC: A Comprehensive Study on Biological Processes, Anti-Inflammatory Effects, and Myocardial Toxicity

Li, X., Wang, Q., Liu, L., Shi, Y., Hong, Y., Xu, W., Xu, H., Feng, J., Xie, M., Li, Y., et al. (2024) · Pharmaceuticals · doi:10.3390/ph17040524 · Cited by 11 · see citing works

North American pawpaw (Asimina triloba L.) fruit: A critical review of bioactive compounds and their bioactivities

Adainoo, B. (2024) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2024.104530 · Cited by 10 · see citing works

Amelioration of diabetic retinopathy in db/db mice by treatment with different proportional three active ingredients from Tibetan medicine Berberis dictyophylla F

Li, R., Ai, X., Hou, Y., Lai, X., Meng, X., & Wang, X. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114190 · Cited by 10 · see citing works

Magnoflorine attenuates Ang II-induced cardiac remodeling via promoting AMPK-regulated autophagy

Zhu, M., Hu, J., Pan, Y., Jiang, Q., & Shu, C. (2024) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-24-130 · Cited by 9 · see citing works

Salbutamol Attenuates Diabetic Skeletal Muscle Atrophy by Reducing Oxidative Stress, Myostatin/GDF-8, and Pro-Inflammatory Cytokines in Rats

Kumar, A., Prajapati, P., Singh, G., Kumar, D., Mishra, V., Kim, S., Raorane, C. J., Raj, V., & Kushwaha, S. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15082101 · Cited by 9 · see citing works

Salbutamol ameliorates skeletal muscle wasting and inflammatory markers in streptozotocin (STZ)-induced diabetic rats

Kumar, A., Prajapati, P., Raj, V., Kim, S., Mishra, V., Raorane, C. J., Raj, R., Kumar, D., & Kushwaha, S. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110883 · Cited by 8 · see citing works

Allantoin reduces glucotoxicity and lipotoxicity in a type 2 diabetes rat model by modulating the PI3K and MAPK signaling pathways

Zhao, Y., Qiao, M., Wang, X.-M., Luo, X., Yang, J.-H., & Hu, J.-P. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e34716 · Cited by 8 · see citing works

Molecules and targets of antidiabetic interest

Gawli, K., & Bojja, K. S. (2023) · Phytomedicine Plus · doi:10.1016/j.phyplu.2023.100506 · Cited by 7 · see citing works

Phytonutrients as Potential Dietary Supplements to Ameliorate Sarcopenia via the Involvement of Autophagic Pathway

Sun, Y., Zheng, Q., Sun, J., Wang, L., & Li, Y. (2023) · Food Reviews International · doi:10.1080/87559129.2023.2274487 · Cited by 6 · see citing works

Phytochemical analysis and in vitro and in vivo antioxidant properties of Plagiorhegma dubia Maxim as a medicinal crop for diabetes treatment

Sun, H., Chen, M., He, X., Sun, Y., Feng, J., Guo, X., Li, L., Zhu, J., Xia, G., & Zang, H. (2023) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2023.104788 · Cited by 6 · see citing works

Plant‐Derived Treatments for Different Types of Muscle Atrophy

Wang, X., Tang, X., Wang, Y., Zhao, S., Xu, N., Wang, H., Kuang, M., Han, S., Jiang, Z., & Zhang, W. (2025) · Phytotherapy Research · doi:10.1002/ptr.8420 · Cited by 5 · see citing works

The Critical Role of Autophagy in the Pathogenesis of Diabetic Osteoporosis: Mechanisms and Therapeutic Measures

Hou, K., Shi, W., Xu, K., Wang, T., & Zhang, Y. (2025) · Drug Design Development and Therapy · doi:10.2147/dddt.s554555 · Cited by 5 · see citing works

Resistance Exercise Counteracts Skeletal Muscle Atrophy in T2DM Mice by Upregulating FGF21 and Activating PI3K/Akt Pathway

Ma, X., Rao, Z., Jin, Z., Lu, Y., Sun, Z., & Zheng, L. (2025) · Biomolecules · doi:10.3390/biom16010003 · Cited by 5 · see citing works

Effects of Geniposide and Geniposidic Acid on Fluoxetine-Induced Muscle Atrophy in C2C12 Cells

Huang, S., Lin, S.-Y., Chen, M., Peng, C., & Hsieh, C.-L. (2021) · Processes · doi:10.3390/pr9091649 · Cited by 5 · see citing works

A Plantaginis Semen-Coptidis Rhizoma compound alleviates type 2 diabetic mellitus in mice via modulating AGEs-RAGE pathway.

Liu, P., Yan, X., Pu, J., Liao, Q., Wang, K., Lan, J., Wang, R., Wang, Z.-T., Ding, L.-L., & Yang, L. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116290 · Cited by 5 · see citing works

Magnoflorine inhibits cisplatin-induced protective autophagy by down-regulating HMGB1 and increases drug sensitivity in drug-resistant ovarian cancer cells

(2024) · European Journal of Gynaecological Oncology · doi:10.22514/ejgo.2024.018 · Cited by 3 · see citing works

Effects and mechanisms of phytochemicals on skeletal muscle atrophy in glucolipid metabolic disorders: current evidence and future perspectives

Li, M., Qin, Y., Geng, R., Fang, J., Kang, S., Huang, K., & Tong, T. (2025) · Food Innovation and Advances · doi:10.48130/fia-0025-0009 · Cited by 2 · see citing works

Magnoflorine presents an antifatigue effect in acute exercise-treated fatigued mice via protecting against hepatic oxidative and inflammatory damage

Zhang, L., Wang, P., Sun, Z., Su, D., & Maiwulanjiang, M. (2025) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923973.2025.2567326 · Cited by 2 · see citing works

Coffee intake (Coffea arabica L.) reduces advanced glycation end product (AGEs) formation and platelet aggregation in diabetic rats

Silvério, A. D. S. D., Pereira, R. G. F. A., Duarte, S. M. D. S., Figueiredo, S. A., Paula, F. B. D. A., Araújo, T. H., Ferreira, C. D. S., Salles, B. C. C., Viana, A. L. M., Ferreira, E. B., et al. (2021) · Revista de ciencias farmaceuticas · doi:10.4322/2179-443x.0711 · Cited by 2 · see citing works

Mechanism of Bile‐Processed Coptidis Rhizoma to Treat Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus Based on UPLC‐Q‐TOF/MS and Network Pharmacology

Dong, Z., Yang, J., Tian, M., Wang, X., Qin, X., Huang, Q., & Wang, J. (2023) · ChemistrySelect · doi:10.1002/slct.202204236 · Cited by 2 · see citing works

Antioxidative and Anti-inflammatory Effects of Plant-derived Hypoglycemic Medicines: An In vivo/In vitro Systematic Review

Adel-Mehraban, M. S., Tabatabaei‐Malazy, O., Manayi, A., Alatab, S., Mohseni, S., Fana, S. E., Asili, P., Bahramsoltani, R., Esmaeili, F., & Azizi, B. (2024) · Current Topics in Medicinal Chemistry · doi:10.2174/0115680266295032240415064750 · Cited by 1 · see citing works

FOXO transcription factors - a potential therapeutic target in civilization diseases.

Przezak, A., Sroczyński, T., & Bielka, W. (2021) · Farmacja Polska · doi:10.32383/farmpol/132182 · Cited by 1 · see citing works

[Mibefradil improves skeletal muscle mass, function and structure in obese mice].

Wu, J., Wu, Y., Yang, Y., Yu, J., Fu, R., Sun, Y., & Xiao, Q. (2022) · PubMed Central · doi:10.12122/j.issn.1673-4254.2022.07.10 · Cited by 1 · see citing works

Study The Mechanism of Huangdi Anxiao Capsules In The Treatment of T2DM of Using UPLC-Q-TOF-MSE Combined With Network PharmacologicalPreprint

Zhang, W., Li, S., Zhu, M., Fang, Z. H., Liu, X. C., & Gao, J. (2022) · Research Square · doi:10.21203/rs.3.rs-1199441/v1

Transcriptome sequencing reveals candidate genes and signaling pathways for skeletal muscle development in Ningxiang pigPreprint

Yu, Z., Xu, X., Ai, N., Zhang, P., Zhao, J., Li, X., Tang, S., & Ma, H. (2023) · Research Square · doi:10.21203/rs.3.rs-3320910/v1

Biomolecular Mechanism of Herbal Medicine on Muscle Atrophy in Type 2 Diabetes Mellitus Rats: Systematic Review

Kuswandi, A., Ikram, N. K. K., & Muchtaridi, M. (2024) · Indonesian Journal of Pharmaceutical Science and Technology · doi:10.24198/ijpst.v11i1.50895

Magnoflorine and its structural diversity: mechanisms, and drug discovery opportunities a review

Nazir, M. M., Mustafa, G., Saeed, S., Ghaffar, W., Farzeen, I., Masood, A., & Ashraf, A. S. (2026) · Molecular Diversity · doi:10.1007/s11030-025-11440-y

Brain-muscle axis regulation of neuroinflammation and sarcopenia in Parkinson’s disease: the bridging role of lactylation

Wang, M., Huang, H., Lan, X., Yin, A., Deng, Q., Zhong, Y., & Wang, M. (2026) · Neurological Sciences · doi:10.1007/s10072-026-09199-7

Emerging Promise of Sulforaphane in Autism: A Comprehensive Review of Its Therapeutic Potential and Mechanisms

Zhang, X., He, Q., Zhu, Y. Y., Lorimer, G. H., Bayram, H., Ghiladi, R. A., & Wang, J. (2026) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.6c00282

Tinospora Cordifolia Protects from Skeletal Muscle Atrophy by Alleviating Oxidative Stress and Inflammation Induced by Sciatic Denervation

Sharma, B., Dutt, V., Kaur, N., Mittal, A., & Dabur, R. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.112720 · Cited by 34 · see citing works

Effect of Tinospora cordifolia on Skeletal Muscle Atrophy in Mice Model

Sharma, B. (2019) · Shodhganga

Influence of dietary cobalt on nutrient digestibility and serum cobalt concentrations in horses

LeCompte, R. A., Nielsen, B. D., Robison, C. I., Schott, H. C., Herdt, T. H., & Larson, C. K. (2017) · Journal of Equine Veterinary Science · doi:10.1016/j.jevs.2017.03.116

Modulation of morphology and some gluconeogenic enzymes ac-tivity by Tinospora cordifolia (Willd.) in diabetic rat kidney

Nagaraja Puranik., K., Kammar, K. F., & Devi, S. (2007) · Biomedical Research-tokyo · Cited by 19 · see citing works

Codonopsis lanceolata and its active component Tangshenoside I ameliorate skeletal muscle atrophy via regulating the PI3K/Akt and SIRT1/PGC-1α pathways

Kim, T.-Y., Park, K.-T., & Choung, S. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154058 · Cited by 33 · see citing works