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Identification of commensal gut bacterial strains with lipogenic effects contributing to NAFLD in children

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Serum Fibrinogen-Like Protein 1 Levels in Obese Patients Before and After Laparoscopic Sleeve Gastrectomy: A Six-Month Longitudinal Study

Dilimulati, D., Du, L., Huang, X., Jayachandran, M., Cai, M., Zhang, Y., Zhou, D., Zhu, J., Su, L., Zhang, M., et al. (2022) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s374011 · Cited by 6 · see citing works

Metabolic Dysfunction-Associated Steatotic Liver Disease and Sarcopenia: Review of Literature

Nishikawa, H., Kim, S. K., Yoshio, S., & ASAI, A. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15041661 · Cited by 5 · see citing works

Serum fibrinogen-like protein 1 as a novel biomarker in polycystic ovary syndrome: a case–control study

Zhang, Y., Dilimulati, D., Chen, D., Cai, M., You, H., Sun, H., Gao, X., Shao, X., Zhang, M., & Qu, S. (2022) · Journal of Endocrinological Investigation · doi:10.1007/s40618-022-01844-0 · Cited by 6 · see citing works

Hepatic miR‑215 target Rictor and modulation of hepatic insulin signalling in rats

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Impacts of Different Modes of Bariatric Surgery on Plasma Levels of Hepassocin in Patients with Diabetes Mellitus

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Regulatory Role of FGL ‐1 in Interorgan Communication by Controlling T Cell Homeostasis During the Onset of Sjögren Disease

Otsuka, K., Ushio, A., Nagao, R., Matsuzawa, S., Arakaki, R., Fukuta, K., Mouri, Y., Tsunematsu, T., & Ishimaru, N. (2025) · Arthritis & Rheumatology · doi:10.1002/art.43236 · Cited by 3 · see citing works

The FGL-1/LAG-3 Axis is Associated With Disease Course in Alcohol-associated Hepatitis: A Preliminary Report

Pedersen, L., Eriksen, L. L., Brix, F. H., Vilstrup, H., Deleuran, B. W., Sandahl, T. D., & Støy, S. H. (2024) · Journal of Clinical and Experimental Hepatology · doi:10.1016/j.jceh.2024.102424 · Cited by 2 · see citing works

Fibrinogen superfamily proteins: Key regulators in hepatic disorders

Qu, R.-H., Rong, Y., Ni, W.-Z., Huang, X.-L., Chen, Y.-Z., & Li, H. (2025) · World Journal of Experimental Medicine · doi:10.5493/wjem.v15.i3.106677 · Cited by 2 · see citing works

Hepatokines modulation in obesity: which exercise training model is better in men with obesity?

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Unraveling fibrinogen-like protein 1’s role in immune regulation

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Lean metabolic dysfunction-associated steatotic liver disease: Current insights and knowledge gaps

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Inflammatory Overtones of Organokines in Metabolic Syndrome and Type 2 Diabetes

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Compensatory Increase of Serum Hepassocin Protects Hyperthyroidism-Induced Hepatic Dysfunction

Wang, C., Lin, C., Chou, H., Wang, C., Liang, Y.-C., Wu, H., & Ou, H. (2023) · Biomedicines · doi:10.3390/biomedicines11071936 · Cited by 1 · see citing works

Ablation of Hepatocyte Derived‐ FGL1 Does Not Aggravate Metabolic Dysfunction‐Associated Steatotic Liver Disease

Personnaz, J., Cannizzo, L., Martin, C. M. P., Desquesnes, A., Sotin, M., DaSilva, J., Perrier, P., Guillou, H., & Kautz, L. (2025) · The FASEB Journal · doi:10.1096/fj.202501997r · Cited by 1 · see citing works

Increased Serum Angiopoietin-like Peptide 4 in Impaired Glucose Tolerance and Diabetes Subjects with or Without Hepatic Steatosis

Lin, M., Li, C., Wu, H., Lee, C., Chen, H.-P., Ou, H., & Kuo, H. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14217599 · Cited by 1 · see citing works

The Association of Non Viral Liver Diseases from NAFLD to NASH to HCC with the Pandemic of Obesity, Type 2 Diabetes, or Diabesity & Metabolic Syndrome Etiopathogenetic Correlation along with Utilization for Diagnostic & Therapeutic Purposes-A Systematic Review

Kaur, K. K., Allahbadia, G., & Singh, M. (2021) · Journal of Endocrinology Research · doi:10.30564/jer.v3i2.3520 · Cited by 1 · see citing works

The changes of serum fibrinogen-like protein 1 levels associated with improved liver function and uric acid after laparoscopic sleeve gastrectomyPreprint

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Treatment of non-alcoholic steatohepatitis with recombinant Orosomucoid 2, an acute phase protein that attenuates the Erk1/2-PPARγ-Cd36 signaling pathwayPreprint

Li, L., Sun, H., Chen, J., Ding, C., Yang, X., Han, H., & Sun, Q. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.22.513320 · Cited by 1 · see citing works

Immunological and molecular mechanisms in NAFLD

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Stéatose et résistance à l’insuline : implication des hépatokines

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Rôle des hépatokines dans le dialogue inter-organes en physiologie et physiopathologie

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Markers of Liver Function and Insulin Resistance

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Markers of Liver Function and Insulin Resistance

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Serum Cardiotrophin-1 Concentration Is Negatively Associated with Controlled Attenuation Parameters in Subjects with Non-Alcoholic Fatty Liver Disease

Liao, Y., Wu, J.-S., Chou, H., Kuo, H., Lee, C., Wu, H., Li, C., & Ou, H. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12072741

Investigation of maternal serum hepassocin concentrations in pregnant women with gestational diabetes mellitus: a prospective case-control study

Çakmak, A., Kale, İ., & Muhçu, M. (2023) · Zeitschrift für Geburtshilfe und Neonatologie · doi:10.1055/a-2096-6339

Ablation of hepatocyte derived-FGL1 does not aggravate metabolic dysfunction-associated steatotic liver disease and hepatocellular carcinomaPreprint

Personnaz, J., Cannizzo, L., Martin, C. M. P., Desquesnes, A., Sotin, M., DaSilva, J., Perrier, P., Guillou, H., & Kautz, L. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.23.628701

The FGL1-LAG-3 axis attenuates melanoma-induced cachexia in mice

Liu, W., Wang, L., Jin, S., Liu, T., Qian, Y., & Lin, P. (2026) · Cancer & Metabolism · doi:10.1186/s40170-025-00418-x

FGL1 modulates macrophage function and enhances liver repair through LAG3-TNFR1 axis

Wu, Y., Fang, Q., Chen, Y., Huang, L., Zhang, W., Huang, Y., Xu, X., Chen, X., Wu, F., & Xu, W. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.116209

Hepassocin drives EGFR-dependent endothelial atherogenic activation via NOX1/ROS amplification and p38 signaling

Pyo, M. K., Park, H. S., Ko, J. H., Lim, D. S., Gwon, H. J., EL-Aty, A. M. A., Yağan, R., Song, J.-H., Shin, Y. K., Jeong, J. H., et al. (2026) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2026.110820

Hepatokine FGL1 drives endothelial injury and atherogenesis via integrin β1-mediated endothelial–mesenchymal transition

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Unsaturated Fatty Acids Increase the Expression of Hepassocin through a Signal Transducer and Activator of Transcription 3‐Dependent Pathway in HepG2 Cells

Cheng, K., Ou, H., Hung, H., Li, C., Fan, K., Wu, J., Wu, H., & Chang, C. (2018) · Lipids · doi:10.1002/lipd.12099 · Cited by 26 · see citing works

Hepassocin: a novel hepatokine

Lyu, X. (2019) · Int J Endocrinol Metab · doi:10.3760/cma.j.issn.1673-4157.2019.05.011

HPS protects the liver against steatosis, cell death, inflammation, and fibrosis in mice with steatohepatitis

Yang, Y., Liu, X., Chen, H., Wang, P., Yao, S., Zhou, B., Yin, R., Li, C., Wu, C., Yang, X., et al. (2022) · FEBS Journal · doi:10.1111/febs.16430 · Cited by 14 · see citing works

Introduction

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Low doses of Bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver

Marmugi, A., Ducheix, M.-S., Lasserre, M.-F., Polizzi, M. A., Paris, A., Priymenko, N., Bertrand‐Michel, J., Pineau, T., Guillou, H., Martin, P. G. P., et al. (2012) · Annales d Endocrinologie · doi:10.1016/j.ando.2012.07.717 · Cited by 20 · see citing works