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p53 Requires an Intact C-Terminal Domain for DNA Binding and Transactivation

Kim, Hyunjung, Kim, Kyunghwan, Choi, Jongkyu, Heo, Kyu, Baek, Hwa Jin, Roeder, Robert G., An, Woojin·2012·Journal of Molecular Biology

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Citations

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Research works printed but not linked: 24

  1. Speidel, 2006, Dissection of transcriptional and non-transcriptional p53 activities in the response to genotoxic stress, Oncogene, 25, 940, 10.1038/sj.onc.1209126 · DOI
  2. Murray-Zmijewski, 2008, A complex barcode underlies the heterogeneous response of p53 to stress, Nat. Rev. Mol. Cell Biol., 9, 702, 10.1038/nrm2451 · DOI · Paper page
  3. Boehme, 2009, Regulation of p53—insights into a complex process, Crit. Rev. Biochem. Mol. Biol., 44, 367, 10.3109/10409230903401507 · DOI
  4. Zambetti, 1992, Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element, Genes Dev., 6, 1143, 10.1101/gad.6.7.1143 · DOI · Paper page
  5. Espinosa, 2001, Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment, Mol. Cell, 8, 57, 10.1016/S1097-2765(01)00283-0 · DOI · Paper page
  6. Joerger, 2007, Structural biology of the tumor suppressor p53 and cancer-associated mutants, Adv. Cancer Res., 97, 1, 10.1016/S0065-230X(06)97001-8 · DOI · Paper page
  7. Wang, 1994, p53 domains: structure, oligomerization, and transformation, Mol. Cell. Biol., 14, 5182, 10.1128/MCB.14.8.5182 · DOI · Paper page
  8. Ahn, 2001, The C-terminus of p53: the more you learn the less you know, Nat. Struct. Biol., 8, 730, 10.1038/nsb0901-730 · DOI
  9. Hupp, 1992, Regulation of the specific DNA binding function of p53, Cell, 71, 875, 10.1016/0092-8674(92)90562-Q · DOI · Paper page
  10. Abarzua, 1995, Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53, Cancer Res., 55, 3490
  11. Hupp, 1995, Small peptides activate the latent sequence-specific DNA binding function of p53, Cell, 83, 237, 10.1016/0092-8674(95)90165-5 · DOI · Paper page
  12. Selivanova, 1997, Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain, Nat. Med., 3, 632, 10.1038/nm0697-632 · DOI · Paper page
  13. Selivanova, 1999, Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain, Mol. Cell. Biol., 19, 3395, 10.1128/MCB.19.5.3395 · DOI · Paper page
  14. Ayed, 2001, Latent and active p53 are identical in conformation, Nat. Struct. Biol., 8, 756, 10.1038/nsb0901-756 · DOI
  15. Kaeser, 2002, Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo, Proc. Natl Acad. Sci. USA, 99, 95, 10.1073/pnas.012283399 · DOI · Paper page
  16. McKinney, 2002, Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein, Mol. Cell. Biol., 22, 6797, 10.1128/MCB.22.19.6797-6808.2002 · DOI
  17. Gohler, 2002, Specific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain, J. Biol. Chem., 277, 41192, 10.1074/jbc.M202344200 · DOI
  18. Tafvizi, 2010, A single-molecule characterization of p53 search on DNA, Proc. Natl Acad. Sci. USA, 108, 563, 10.1073/pnas.1016020107 · DOI · Paper page
  19. McKinney, 2004, p53 linear diffusion along DNA requires its C terminus, Mol. Cell, 16, 413, 10.1016/j.molcel.2004.09.032 · DOI · Paper page
  20. An, 2004, Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53, Cell, 117, 735, 10.1016/j.cell.2004.05.009 · DOI · Paper page
  21. Gu, 1997, Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain, Cell, 90, 595, 10.1016/S0092-8674(00)80521-8 · DOI · Paper page
  22. Hupp, 1994, Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases, Cold Spring Harbor Symp. Quant. Biol., 59, 195, 10.1101/SQB.1994.059.01.024 · DOI
  23. Jayaraman, 1995, Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus, Cell, 81, 1021, 10.1016/S0092-8674(05)80007-8 · DOI · Paper page
  24. An, 2004, Reconstitution and transcriptional analysis of chromatin in vitro, Methods Enzymol., 377, 460, 10.1016/S0076-6879(03)77030-X · DOI

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Metadata

Authors
Kim, H., Kim, K., Choi, J., Heo, K., Baek, H. J., Roeder, R. G., & An, W.
Venue
Journal of Molecular Biology
Publisher
Elsevier BV
Published
2012-02
Volume
415
Issue
5
Pages
843-854
ISSN
0022-2836
Cited by
50
References
5
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
  • National Institutes of Health (GM84209, DMC-1005001, CA129325)
  • ACS research scholar

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CoChat. (2026). Citation check: p53 Requires an Intact C-Terminal Domain for DNA Binding and Transactivation. https://app.cochat.ai/papers/10.1016/j.jmb.2011.12.001
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Kim, H., Kim, K., Choi, J., Heo, K., Baek, H. J., Roeder, R. G., & An, W. (2012). p53 Requires an Intact C-Terminal Domain for DNA Binding and Transactivation. Journal of Molecular Biology. https://doi.org/10.1016/j.jmb.2011.12.001

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.