Daily pain variations among patients with hand, hip, and knee osteoarthritis
Open accessAbstract
Objective This study examined within-day osteoarthritis (OA)-related pain patterns and associated patient characteristics.Methods Participants with physician diagnoses and self-reported symptoms of hand (N=40), hip (N=32), and knee (N=85) OA recorded pain using a handheld computer on one weekday and one weekend day, with ratings beginning immediately after waking, then approximately every 2h following. Pain was rated on a sliding visual analog scale with hidden coding of 1-100. Multivariable linear mixed models examined associations of patient demographic characteristics, enrollment site (Durham VA Medical Center vs Duke University Medical Center), joint site, body mass index, and pain medication use with within-day pain range (maximum minus minimum pain rating) and area under the curve (AUC) of pain ratings, which incorporates the magnitude of all pain measurements.Results Pain patterns differed substantially across individuals. The sample means of the average, maximum, and minimum weekday pain scores were 35.3, 54.4, and 17.9, respectively. The mean pain range was 36.4, and the mean pain AUC was 564.3 (possible range: 16-1600). Pain scores were similar on weekends. In multivariable mixed models, both knee and hip OA were associated with a greater within-day pain range than hand OA. Only VA enrollment site was associated with a significantly greater pain AUC.Conclusion There is substantial within-day range in OA-related pain. Both pain range and overall within-day magnitude vary according to patient characteristics. Patients' records of within-day pain patterns could be used in clinical encounters to tailor recommendations for the timing of medication use and behavioral strategies.
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Pain-related variables such as pain intensity, mood, and fatigue can vary across and within days in patients with chronic pain.
“This is problematic because pain-related variables, such as pain intensity, mood, and fatigue can vary across and within days [22,23], even in patients with chronic pain such as osteoarthritis [24], rheumatic diseases [25], multiple sclerosis [23] and fibromyalgia [26].”
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Cites
Applied Longitudinal Data Analysis: Modeling Change and Event Occurrence
Singer, J. D., & Willett, J. B. (2003) · doi:10.1093/acprof:oso/9780195152968.001.0001 · Cited by 10,647 · see citing works
Applied Linear Statistical Models
Ziegel, E. R., Neter, J., Wasserman, W., & Kutner, M. (1992) · Technometrics · doi:10.2307/1269588 · Cited by 9,906 · see citing works
Littell, R. C., Milliken, G. A., Stroup, W. W., Wolfinger, R. D., & Schabenberger, O. (2006) · CERN Document Server (European Organization for Nuclear Research) · Cited by 2,924 · see citing works
Applied Linear Statistical Models
Senter, H. F. (2008) · Journal of the American Statistical Association · doi:10.1198/016214508000000300 · Cited by 1,394 · see citing works
Jensen, M. P. (2003) · Journal of Pain · doi:10.1016/s1526-5900(03)00716-8 · Cited by 1,318 · see citing works
Patient compliance with paper and electronic diaries
Stone, A. A., Shiffman, S., Schwartz, J. E., Broderick, J. E., & Hufford, M. R. (2003) · Controlled Clinical Trials · doi:10.1016/s0197-2456(02)00320-3 · Cited by 910 · see citing works
Applied Longitudinal Data Analysis: Modeling Change and Event Occurrence
Anderson, C. J. (2005) · Journal of the American Statistical Association · doi:10.1198/jasa.2005.s7 · Cited by 848 · see citing works
Are Patients at Veterans Affairs Medical Centers Sicker?
Agha, Z., Lofgren, R. P., VanRuiswyk, J. V., & Layde, P. M. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.21.3252 · Cited by 744 · see citing works
Increasing the reliability and validity of pain intensity measurement in chronic pain patients
Jensen, M. P., & McFarland, C. A. (1993) · Pain · doi:10.1016/0304-3959(93)90148-i · Cited by 720 · see citing works
Health-Related Quality of Life in Patients Served by the Department of Veterans Affairs
Kazis, L. E., Miller, D. R., Clark, J. A., Skinner, K. M., Lee, A. F., Rogers, W. H., Spiro, A., Payne, S. M. C., Fincke, B. G., Selim, A. J., et al. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.6.626 · Cited by 565 · see citing works
Palermo, T. M., Valenzuela, D., & Stork, P. P. (2003) · Pain · doi:10.1016/j.pain.2003.10.005 · Cited by 346 · see citing works
Creamer, P., Lethbridge‐Çejku, M., & Hochberg, M. C. (1999) · PubMed · Cited by 292 · see citing works
Straub, R. H., & Cutolo, M. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22368 · Cited by 262 · see citing works
Electronic diaries for monitoring chronic pain: 1-year validation study
Jamison, R. N., Raymond, S. A., Levine, J. G., Slawsby, E. A., Nedeljković, S. S., & Katz, N. P. (2001) · Pain · doi:10.1016/s0304-3959(00)00450-4 · Cited by 249 · see citing works
Stone, A. A., Broderick, J. E., Porter, L. S., & Kaell, A. T. (1997) · Arthritis & Rheumatism · doi:10.1002/art.1790100306 · Cited by 240 · see citing works
Affleck, G., Tennen, H., Keefe, F. J., Lefebvre, J. C., Kashikar-Zuck, S., Wright, K., Starr, K., & Caldwell, D. S. (1999) · Pain · doi:10.1016/s0304-3959(99)00167-0 · Cited by 218 · see citing works
Self-citationCircadian variation in disease activity in rheumatoid arthritis.
Harkness, J. A., Richter, M. B., Panayi, G. S., de Pette, K. V., Unger, A., Pownall, R., & Geddawi, M. (1982) · BMJ · doi:10.1136/bmj.284.6315.551 · Cited by 171 · see citing works
Health‐related quality of life and health service use among older adults with osteoarthritis
Dominick, K. L., Ahern, F. M., Gold, C. H., & Heller, D. A. (2004) · Arthritis Care & Research · doi:10.1002/art.20390 · Cited by 153 · see citing works
Cutolo, M., SERIOLO, B., Craviotto, C., Pizzorni, C., & Sulli, A. (2003) · Annals of the Rheumatic Diseases · doi:10.1136/ard.62.7.593 · Cited by 135 · see citing works
The impact of momentary pain and fatigue on physical activity in women with osteoarthritis
Murphy, S. L., Smith, D. M., Clauw, D. J., & Alexander, N. B. (2008) · Arthritis Care & Research · doi:10.1002/art.23710 · Cited by 134 · see citing works
Stone, A. A., Broderick, J. E., Kaell, A. T., DelesPaul, P. A. E. G., & Porter, L. E. (2000) · The Journal of Pain · doi:10.1054/jpai.2000.7568 · Cited by 133 · see citing works
e-Ouch: Usability Testing of an Electronic Chronic Pain Diary for Adolescents With Arthritis
Stinson, J., Pétroz, G. C., Tait, G., Feldman, B. M., Streiner, D. L., McGrath, P. J., & Stevens, B. (2006) · Clinical Journal of Pain · doi:10.1097/01.ajp.0000173371.54579.31 · Cited by 131 · see citing works
Salaffi, F., Angelis, R. D., Stancati, A., & Grassi, W. (2005) · PubMed · Cited by 124 · see citing works
Keefe, F. J., Affleck, G. G., France, C. R., Emery, C. F., Waters, S. J., Caldwell, D. S., Stainbrook, D., Hackshaw, K. V., Fox, L. C., & Wilson, K. S. (2004) · Pain · doi:10.1016/j.pain.2004.03.028 · Cited by 120 · see citing works
Self-citationRhythmic variations in pain perception in osteoarthritis of the knee.
Bellamy, N., Sothern, R. B., & Campbell, J. (1990) · PubMed · Cited by 115 · see citing works
Rhythmic variations in pain, stiffness, and manual dexterity in hand osteoarthritis
Bellamy, N., Sothern, R. B., Campbell, J., et al. (2002) · Annals of the Rheumatic Diseases · doi:10.1136/ard.61.12.1075 · Cited by 109 · see citing works
Kowanko, I. C., Pownall, R., Knapp, M., Swannell, A. J., & Mahoney, P. (1981) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1981.tb01153.x · Cited by 103 · see citing works
Hutchings, A., Calloway, M. O., Choy, E., Hooper, M. M., Hunter, D. J., Jordan, J. M., Zhang, Y., Başer, O., Long, S. R., & Palmer, L. A. (2007) · PubMed · Cited by 99 · see citing works
Bellamy, N., Sothern, R. B., Campbell, J. A., et al. (1991) · Annals of the Rheumatic Diseases · doi:10.1136/ard.50.4.243 · Cited by 98 · see citing works
Validity of 24-h recall ratings of pain severity: Biasing effects of “Peak” and “End” pain
Jensen, M. P., Mardekian, J., Lakshminarayanan, M. Y., & Boye, M. E. (2007) · Pain · doi:10.1016/j.pain.2007.10.006 · Cited by 92 · see citing works
Focht, B. C., Ewing, V., Gauvin, L., & Rejeski, W. J. (2002) · Annals of Behavioral Medicine · doi:10.1207/s15324796abm2403_05 · Cited by 82 · see citing works
Kowanko, I. C., Knapp, M. S., Pownall, R., & Swannell, A. J. (1982) · Annals of the Rheumatic Diseases · doi:10.1136/ard.41.5.453 · Cited by 82 · see citing works
Dominick, K. L., Golightly, Y. M., & Jackson, G. L. (2006) · PubMed · Cited by 71 · see citing works
Self-citationSorbi, M. J., Peters, M. L., Kruise, D. A., Maas, C. J. M., Kerssens, J. J., Verhaak, P. F. M., & Bensing, J. M. (2005) · Clinical Journal of Pain · doi:10.1097/01.ajp.0000148624.46756.fa · Cited by 70 · see citing works
Paradowski, P. T., Englund, M., Lohmander, S. L., & Roos, E. M. (2005) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-3-59 · Cited by 67 · see citing works
Diabetes in Nonveterans, Veterans, and Veterans Receiving Department of Veterans Affairs Health Care
Reiber, G. E., Koepsell, T. D., Maynard, C. C., Haas, L. B., & Boyko, E. J. (2004) · Diabetes Care · doi:10.2337/diacare.27.suppl_2.b3 · Cited by 65 · see citing works
Racial variations in self-reported osteoarthritis symptom severity among veterans
Golightly, Y. M., & Dominick, K. L. (2005) · Aging Clinical and Experimental Research · doi:10.1007/bf03324608 · Cited by 63 · see citing works
Self-citationDemographic Variables and Chronic Pain
Hunter, J. P. (2001) · Clinical Journal of Pain · doi:10.1097/00002508-200112001-00006 · Cited by 32 · see citing works
Pilot Study of Pain and Coping Among Patients With Osteoarthritis
Allen, K. D., Golightly, Y. M., & Olsen, M. K. (2006) · JCR Journal of Clinical Rheumatology · doi:10.1097/01.rhu.0000221801.63880.3f · Cited by 29 · see citing works
Self-citationCircadian variation in biochemical assessments used to monitor rheumatoid arthritis.
Sitton, N. G., Taggart, A. J., Dixon, J. S., et al. (1984) · Annals of the Rheumatic Diseases · doi:10.1136/ard.43.3.444 · Cited by 18 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- O'Reilly S, Doherty M. Clinical features of osteoarthritis and standard ap- proaches to the diagnosis. In: Brandt KD, Doherty M, Lohmander LS, Eds. Osteoarthritis. Oxford: Oxford University Press; 1998
- Dominick KL, Golightly YM, Jackson GL. Arthritis prevalence and symp- toms among U.S. non-veterans, veterans, and veterans receiving De- partment of Veterans Affairs health care. J Rheumatol 2006;33: 348e54.
- Yeh S-T. Using trapezoidal rule for area under the curve calculation. In: SAS Users Group International Conference 27, 2002, Orlando, FL, 2002, pp. 229e32.
Cited by
Sorted by citations
The epidemiology and impact of pain in osteoarthritis
Neogi, T. (2013) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2013.03.018 · Cited by 1,730 · see citing works
Ecological momentary assessment methodology in chronic pain research: a systematic review
May, M., Junghaenel, D. U., Ono, M., Stone, A. A., & Schneider, S. (2018) · The Journal of Pain · doi:10.1016/j.jpain.2018.01.006 · Cited by 247 · see citing works
Pain and fatigue variability patterns distinguish subgroups of Fibromyalgia patients
Bartley, E. J., Robinson, M. E., & Staud, R. (2018) · The Journal of Pain · doi:10.1016/j.jpain.2017.11.014 · Cited by 83 · see citing works
Suso-Ribera, C., Castilla, D., Zaragozá, I., Mesas, Á., Server, A., Medel, J., & García-Palacios, A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186568 · Cited by 38 · see citing works
- Authors
- Allen, K. D., Coffman, C. J., Golightly, Y. M., Stechuchak, K. M., & Keefe, F. J.
- Affiliations
- Duke University (US)
- Durham VA Medical Center (US)
- Duke Medical Center (US)
- Corresponding author
- Allen, K.D.
- Venue
- Osteoarthritis and Cartilage
- Publisher
- Elsevier BV
- Published
- 2009-10
- Volume
- 17
- Issue
- 10
- Pages
- 1275-1282
- ISSN
- 1063-4584 (ISSN-L)
- OpenAlex
- W1972763487
- Cited by
- 92
- References
- 40
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 6 · 2023: 5 · 2022: 7 · 2021: 11 · 2020: 5 · 2019: 6 · 2018: 6 · 2017: 3 · 2016: 1 · 2015: 4 · 2014: 9 · 2013: 5 · 2012: 5
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Osteoarthritis and Cartilage (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- osteoarthritis, pain patterns, hand osteoarthritis, hip osteoarthritis, knee osteoarthritis, body mass index, analgesic use, veterans
- MeSH terms
- Aged, Female, Hand, Hip, Humans, Knee, Male, Middle Aged, Osteoarthritis, Pain, Pain Measurement, Multivariate Analysis, Area Under Curve, Computers, Handheld
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