Anxiety and depression as risk factors for mortality after coronary artery bypass surgery
Abstract
Objective This retrospective study examined the association between symptoms of depression, anxiety, and mortality risk following coronary artery bypass graft (CABG) surgery.Methods We assessed 440 CABG surgery patients' scores on the Depression Anxiety and Stress Scale (DASS) and followed up mortality status for a median of 5 years, 10 months.Results There were 67 (15%) deaths overall during the follow-up period. Adjusted survival analysis showed that preoperative depressive symptoms were not associated with a significantly higher risk of mortality. Survival analysis with preoperative anxiety adjusted for covariates showed a significantly increased mortality risk [hazard ratio (HR)=1.88 (95% CI=1.12-3.17), P=.02].Conclusion Preoperative anxiety symptoms were significantly associated with increased mortality risk after adjustment for known mortality risk factors. Future research should further explore the simultaneous role of anxiety and depression on mortality following CABG.
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Anxiety disorders are associated with worsened physical health, including a higher risk for cardiovascular diseases and premature mortality.
“In addition to the profound negative impact on individuals’ wellbeing and functioning, they are associated with worsened physical health, including a higher risk for cardiovascular diseases and premature mortality.”
From Moving to Beat Anxiety: Epidemiology and Therapeutic Issues with Physical Activity for Anxiety (2018) · cites this paper as [14]
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- Authors
- Tully, P. J., Baker, R. A., & Knight, J. L.
- Affiliations
- Flinders Medical Centre (AU)
- Flinders University (AU)
- Corresponding author
- Baker, Robert A.
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2008-03
- Volume
- 64
- Issue
- 3
- Pages
- 285-290
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W1964619777
- Cited by
- 211
- References
- 40
- Citations by year
- 2026: 4 · 2025: 10 · 2024: 7 · 2023: 10 · 2022: 13 · 2021: 26 · 2020: 11 · 2019: 6 · 2018: 8 · 2017: 11 · 2016: 14 · 2015: 13 · 2014: 6 · 2013: 11 · 2012: 15
- FWCI
- 11.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Flinders Academic Commons (Flinders University) (submittedVersion)
- Figshare (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Surgery › Cardiac and Coronary Surgery Techniques
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- anxiety, depression, coronary artery bypass grafting, postoperative mortality, preoperative anxiety, depressive symptoms, risk factors, survival analysis, DASS
- MeSH terms
- Adult, Aged, Anxiety Disorders, Coronary Artery Bypass, Demography, Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Middle Aged, Postoperative Complications, Risk Factors
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