Cited by 94Physical Activity and HealthContext-Aware Activity Recognition SystemsCardiovascular and exercise physiology

Accelerometer-measured sedentary time and physical activity—A 15 year follow-up of mortality in a Swedish population-based cohort

Dohrn, Ing-Mari, Sjöström, Michael, Kwak, Lydia, Oja, Pekka, Hagströmer, Maria·2018·Journal of Science and Medicine in Sport

Abstract

Objectives To investigate the associations of objectively assessed sedentary time, light intensity physical activity (PA), moderate to vigorous intensity PA (MVPA), and total PA with all-cause mortality and mortality from cardiovascular disease (CVD) or cancer in a Swedish population-based cohort with 15 years follow-up time.Design Longitudinal prospective cohort study.Methods Data from 851 persons (56% women) ≥35 years at baseline were included. Primary exposure variables were time (min/day) spent sedentary, in light intensity PA and in MVPA, and total counts from an Actigraph 7164 accelerometer. Data on all-cause mortality and mortality from CVD or cancer were obtained from Swedish registers. Cox proportional hazards models estimated hazard ratios (HR) of mortality with 95% confidence intervals (CI).Results Compared with the least sedentary participants, those in the most sedentary tertile had an increased risk of all-cause mortality, HR: 2.7 (1.4, 5.3), CVD mortality, HR: 5.5 (1.4, 21.2) and cancer mortality, HR: 4.3 (1.2, 16.0). For all-cause mortality, those in the highest light intensity PA tertile had a HR 0.34 (0.17, 0.67) compared with the lowest tertile. A similar pattern was found for CVD and cancer mortality. More time spent in MVPA was associated with the largest risk reduction for CVD mortality, with an almost 90% lower risk in the tertile with the most time in MVPA.Conclusions This study confirms a strong inverse relationship between MVPA and mortality, and adds new insight for the understanding of the associations between sedentary time and light intensity PA and mortality.

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Crossref · 10.1016/j.jsams.2017.10.035

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  • Objectively measured physical activity levels, categorized into sedentary behaviour, light PA and MVPA, can be used to assess the risk of cardiovascular and all-cause death.

    “Objectively measured PA levels, categorized into sedentary behaviour, light PA and MVPA, can be used to assess the risk of cardiovascular and all-cause death”
  • MVPA measured with triaxial accelerometers is associated with lower mortality than light physical activity or sedentary behaviour in several US cohorts and a Swedish population-based cohort.

    “Moderate-to-vigorous physical activity (MVPA), measured with the use of triaxial accelerometers, was associated with a lower mortality than light physical activity or sedentary behaviour in several US cohorts and in a Swedish population-based cohort34–38.”
  • Wearable-measured physical activity has an inverse dose-dependent relationship with all-cause mortality.

    “Several studies have shown wearable-measured physical activity to have an inverse dose-dependent relationship with all-cause mortality5,34–38.”

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Authors
Dohrn, I.-M., Sjöström, M., Kwak, L., Oja, P., & Hagströmer, M.
Affiliations
  • Karolinska Institutet (SE)
  • Urho Kaleva Kekkonen Institute (FI)
Corresponding author
Dohrn, Ing-Mari
Venue
Journal of Science and Medicine in Sport
Publisher
Elsevier BV
Published
2018-07
Volume
21
Issue
7
Pages
702-707
ISSN
1440-2440 (ISSN-L)
OpenAlex
W2767587572
Cited by
94
References
33
Citations by year
2026: 4 · 2025: 5 · 2024: 11 · 2023: 4 · 2022: 16 · 2021: 16 · 2020: 13 · 2019: 18 · 2018: 5 · 2017: 2
FWCI
7.69
Type
journal article
Language
en
Update notices
erratum (2019-03-01)
Open access
closed
Locations
  • Journal of science and medicine in sport (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Stockholm County Council
  • the Swedish National Centre for Research in Sports
  • the project ALPHA
  • European Union in the framework of the Public Health Programme
  • Folksam Research Foundation, Sweden
Topics
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Context-Aware Activity Recognition Systems
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
sedentary time, physical activity, light physical activity, moderate-to-vigorous physical activity, accelerometer-measured activity, all-cause mortality, cardiovascular mortality, cancer mortality, long-term follow-up, population-based cohort
MeSH terms
Aged, Cardiovascular Diseases, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Mortality, Neoplasms, Prospective Studies, Risk Factors, Sweden, Time Factors, Exercise, Proportional Hazards Models, Sedentary Behavior, Accelerometry

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