Accelerometer-measured sedentary time and physical activity—A 15 year follow-up of mortality in a Swedish population-based cohort
Abstract
Objectives To investigate the associations of objectively assessed sedentary time, light intensity physical activity (PA), moderate to vigorous intensity PA (MVPA), and total PA with all-cause mortality and mortality from cardiovascular disease (CVD) or cancer in a Swedish population-based cohort with 15 years follow-up time.Design Longitudinal prospective cohort study.Methods Data from 851 persons (56% women) ≥35 years at baseline were included. Primary exposure variables were time (min/day) spent sedentary, in light intensity PA and in MVPA, and total counts from an Actigraph 7164 accelerometer. Data on all-cause mortality and mortality from CVD or cancer were obtained from Swedish registers. Cox proportional hazards models estimated hazard ratios (HR) of mortality with 95% confidence intervals (CI).Results Compared with the least sedentary participants, those in the most sedentary tertile had an increased risk of all-cause mortality, HR: 2.7 (1.4, 5.3), CVD mortality, HR: 5.5 (1.4, 21.2) and cancer mortality, HR: 4.3 (1.2, 16.0). For all-cause mortality, those in the highest light intensity PA tertile had a HR 0.34 (0.17, 0.67) compared with the lowest tertile. A similar pattern was found for CVD and cancer mortality. More time spent in MVPA was associated with the largest risk reduction for CVD mortality, with an almost 90% lower risk in the tertile with the most time in MVPA.Conclusions This study confirms a strong inverse relationship between MVPA and mortality, and adds new insight for the understanding of the associations between sedentary time and light intensity PA and mortality.
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Objectively measured physical activity levels, categorized into sedentary behaviour, light PA and MVPA, can be used to assess the risk of cardiovascular and all-cause death.
“Objectively measured PA levels, categorized into sedentary behaviour, light PA and MVPA, can be used to assess the risk of cardiovascular and all-cause death”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [35]
MVPA measured with triaxial accelerometers is associated with lower mortality than light physical activity or sedentary behaviour in several US cohorts and a Swedish population-based cohort.
“Moderate-to-vigorous physical activity (MVPA), measured with the use of triaxial accelerometers, was associated with a lower mortality than light physical activity or sedentary behaviour in several US cohorts and in a Swedish population-based cohort34–38.”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [35]
Wearable-measured physical activity has an inverse dose-dependent relationship with all-cause mortality.
“Several studies have shown wearable-measured physical activity to have an inverse dose-dependent relationship with all-cause mortality5,34–38.”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [35]
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- Authors
- Dohrn, I.-M., Sjöström, M., Kwak, L., Oja, P., & Hagströmer, M.
- Affiliations
- Karolinska Institutet (SE)
- Urho Kaleva Kekkonen Institute (FI)
- Corresponding author
- Dohrn, Ing-Mari
- Venue
- Journal of Science and Medicine in Sport
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 21
- Issue
- 7
- Pages
- 702-707
- ISSN
- 1440-2440 (ISSN-L)
- OpenAlex
- W2767587572
- Cited by
- 94
- References
- 33
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 11 · 2023: 4 · 2022: 16 · 2021: 16 · 2020: 13 · 2019: 18 · 2018: 5 · 2017: 2
- FWCI
- 7.69
- Type
- journal article
- Language
- en
- Update notices
- erratum (2019-03-01)
- Open access
- closed
- Locations
- Journal of science and medicine in sport (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Stockholm County Council
- the Swedish National Centre for Research in Sports
- the project ALPHA
- European Union in the framework of the Public Health Programme
- Folksam Research Foundation, Sweden
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Context-Aware Activity Recognition Systems
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- sedentary time, physical activity, light physical activity, moderate-to-vigorous physical activity, accelerometer-measured activity, all-cause mortality, cardiovascular mortality, cancer mortality, long-term follow-up, population-based cohort
- MeSH terms
- Aged, Cardiovascular Diseases, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Mortality, Neoplasms, Prospective Studies, Risk Factors, Sweden, Time Factors, Exercise, Proportional Hazards Models, Sedentary Behavior, Accelerometry
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