Brief intervention for women with risky drinking and medical diagnoses: a randomized controlled trial
Open accessAbstract
This is a randomized controlled trial of 511 eligible women treated for diabetes, hypertension, infertility, or osteoporosis on an outpatient basis to test the hypothesis that those randomized to a brief intervention (BI) will drink less than those in the control condition 12 months later. A secondary goal was to identify the characteristics associated with changes in drinking outcome. All 511 completed the initial alcohol assessment, and 96% completed the 12-month follow-up interview. Those receiving the BI also had 3- and 6-month interviews. Four outcomes were assessed: (a) mean drinks per drinking day, (b) percent drinking days, (c) binge episodes defined as four or more drinks per occasion, and (d) weeks of drinking exceeding the National Institute on Alcohol Abuse and Alcoholism sensible drinking limits. Overall, there were no differences in drinking outcome by treatment group. Characteristics associated with changes in drinking, however, were identified to provide possible direction for future investigation.
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In Chang 2011, blinding of participants and personnel was judged high risk because participants and study staff could not be blinded to treatment group assignment.
“Blinding of participants and personnel All outcomes High risk Quote:”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Chang 2011
In Chang 2011, blinding of outcome assessors for objective outcomes was judged low risk because live birth and miscarriage are observer-reported outcomes not involving judgement.
“Blinding of outcome as sessors Objective outcomes Low risk Comment: outcome assessors were not blinded.Live birth and miscarriage were not likely to be influenced, as they are observer-reported outcomes not involving judgement”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Chang 2011
In Chang 2011, blinding of outcome assessors for patient-reported outcomes was judged high risk because the outcome assessor is the participant and is not blinded, and reported behavioural changes regarding drinking are likely to be influenced.
“Blinding of outcome as sessors Patient reported outcome measures High risk Comment: outcome assessor is participant and is not blinded; reported behavioural changes regarding drinking are likely to be influenced, as less drinking is known to be socially desirable”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Chang 2011
In Chang 2011, other sources of bias were judged low risk because the study appeared free of other sources of bias.
“Other sources of bias Low risk Comment: study appears free of other sources of bias”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Chang 2011
In Chang 2011, incomplete outcome data was judged high risk because 161 out of 511 randomised participants were reported to have infertility, but outcome data were available only for 37 participants.
“Incomplete outcome data High risk Comment: in Chang 2011 (table 2), 161 out of 511 participants randomised are reported to have infertility.However outcome data are available only for 37 participants.Study authors were contacted twice for clarification, but no reply was received as of February 2021”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Chang 2011
In Chang 2011, sequence generation was judged low risk because a computer-generated random assignment list was used.
“Sequence generation Low risk Quote:”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Chang 2011
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- Authors
- Chang, G., Fisher, N. D. L., Hornstein, M. D., Jones, J. A., Hauke, S. H., Niamkey, N., Briegleb, C., & Orav, E. J.
- Affiliations
- Brigham and Women's Hospital (US)
- Corresponding author
- Chang, Grace
- Venue
- Journal of Substance Abuse Treatment
- Publisher
- Elsevier BV
- Published
- 2011-09
- Volume
- 41
- Issue
- 2
- Pages
- 105-114
- ISSN
- 0740-5472 (ISSN-L)
- PMC
- PMC3139715
- OpenAlex
- W1979484476
- Cited by
- 23
- References
- 56
- Citations by year
- 2025: 1 · 2021: 2 · 2020: 4 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 7
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Substance Abuse Treatment (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R01AA014678, K24AA000289)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Keywords
- brief intervention, hazardous drinking, women, alcohol consumption, diabetes mellitus, hypertension, infertility, osteoporosis, binge drinking, outpatient care
- MeSH terms
- Adult, Alcohol Drinking, Ethanol, Boston, Central Nervous System Depressants, Data Collection, Diabetes Mellitus, Female, Humans, Hypertension, Infertility, Interview, Psychological, Middle Aged, Osteoporosis, Psychotherapy, Brief, Risk-Taking, Time Factors, Comorbidity, Treatment Outcome
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