Mesenteric revascularization: management and outcomes in the United States, 1988-2006
Open accessAbstract
Background Recent reports have suggested that angioplasty, with and without stenting (PTA/S), may have a lower perioperative mortality rate than open surgery for revascularization of acute (AMI) and chronic mesenteric ischemia (CMI). It is unclear if there has been nationwide adoption of this methodology or whether there is actually a mortality benefit.Methods We identified all patients undergoing surgical (bypass, endarterectomy, or embolectomy) or PTA/S mesenteric revascularization from the Nationwide Inpatient Sample from 1988 to 2006. A diagnosis by International Classification of Diseases, 9th Revisioncoding of AMI or CMI was required for inclusion. We evaluated trends in management during this period and compared in-hospital death and complications between surgical bypass and PTA/S for the years 2000 to 2006.Results From 1988 to 2006, there were 6342 PTA/S and 16,071 open surgical repairs overall. PTA/S increased steadily, surpassing all surgery for CMI in 2002. PTA/S for AMI has also increased and surpassed bypass in 2002 but has not surpassed all surgical procedures for AMI even in 2006. The mortality rate was lower after PTA/S than after bypass for CMI (3.7% vs 13%, P < .01) and AMI (16% vs 28%, P < .01). Bowel resection was more common after bypass than PTA/S for CMI (7% vs 3%, P < .01). This subgroup showed an increased in-hospital mortality rate for both repair types (54% and 25%, respectively).Conclusion PTA/S is being used with increasing frequency for revascularization of CMI and AMI. The lower in-hospital mortality rate for patients, as they are currently being selected, shows that PTA/S is appropriate therapy for selected patients with CMI. Longitudinal data are needed to determine the durability of this benefit. The greater proportion of patients undergoing bowel resection with bypass for AMI suggests a more advanced level of ischemia in this group, making comparison with PTA/S difficult. However, PTA/S may be useful in selected patients with AMI and appropriate anatomy. Further data with greater detail regarding symptomatology and anatomy will clarify appropriate patient selection.
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- Findingown data
AMI revascularization patients were typically older women with multiple comorbidities.
“Patients undergoing revascularization for AMI also tended to be older women with multiple comorbidities.”
Quote in the paperNot a substantial claim - Findingown data
In-hospital mortality after mesenteric revascularization was lower for PTA/S than bypass for AMI (16% vs 28%, P<0.01).
“Mortality was lower after PTA/S than bypass for both CMI (3.7% vs 13%, P<0.01) and AMI (16% vs 28%, P<0.01).”
- Also stated in: § AMI 2000–2006 · plain
“When limiting the comparison of PTA/S to bypass, mortality was still significantly lower with PTA/S (P <.001).”
Quote in the paperSubstantial claim - Also stated in: § AMI 2000–2006 · plain
- Findingown data
For CMI, median hospital stay was shorter with PTA/S than bypass (5 vs 11 days, P<0.001).
“Length of stay was shorter after PTA/S than bypass (Median (range) 5 (0–94) vs 11 (1–135) days, P <.001).”
Quote in the paperSubstantial claim - Findingown data
In CMI multivariate analysis, bypass carried a 5- to 6-fold higher mortality risk than PTA/S.
“On multivariate analysis, mortality was still 5 to 6-fold higher with bypass compared to PTA/S (Table IV).”
Quote in the paperSubstantial claim - Findingown data
For CMI, bowel resection occurred more often with bypass than with PTA/S (7% vs 3%, P<0.01).
“Bowel resection was more common after bypass than PTA/S for CMI (7% vs 3%, P<0.01)”
Quote in the paperNot a substantial claim
- Findingown data
In CMI, hypertension was protective against mortality.
“Hypertension was protective.”
Quote in the paperNot a substantial claim - Findingown data
In CMI, each additional decade of age raised mortality risk by 50%.
“Increasing age was also a predictor of mortality with a 50% increased risk per decade of life.”
Quote in the paperNot a substantial claim - Findingown data
In AMI, bowel resection predicted mortality more strongly than whether PTA/S or bypass was used.
“We found that the need for bowel resection was the primary predictor of mortality with AMI more so than the use of PTA/S versus bypass.”
Quote in the paperSubstantial claim- The authors state this as an assumption: For AMI, bowel resection was assumed to indicate pre-existing ischemic extent rather than a revascularization complication.
- Findingown data
For AMI, in-hospital death occurred in 16% of PTA/S patients and 39% of surgical patients (P<0.001).
“In-hospital mortality was 16% after PTA/S and 39% after surgical repair for AMI (P <.001).”
Quote in the paperSubstantial claim - Findingown data
Gender was not a significant predictor of mortality in AMI.
“Gender was not a significant predictor of mortality.”
Quote in the paperNot a substantial claim - Findingown data
Atrial fibrillation/flutter was more common for AMI than CMI (33% vs 16%, P<0.001).
“Atrial fibrillation and flutter were more common for AMI than CMI as expected (33% vs 16%, P <.001).”
Quote in the paperNot a substantial claim - Findingown data
For CMI, the rates of acute renal failure and bowel resection were about 50% lower with PTA/S than with bypass.
“PTA/S had approximately half the rate of acute renal failure and need for bowel resection.”
Quote in the paperSubstantial claim - Findingown data
In CMI, gender did not significantly affect mortality after PTA/S or open repair.
“There were no significant mortality differences for gender for PTA/S (Male vs Female 4% vs 4%, P =.72) or open repairs (14% vs 16%, P =.66).”
Quote in the paperNot a substantial claim - Findingown data
The NIS contained 6,342 PTA/S and 16,071 open surgical mesenteric revascularizations from 1988 through 2006.
“From 1988 to 2006 there were 6,342 PTA/S and 16,071 open surgical repairs overall.”
Quote in the paperSubstantial claim - Findingown data
For AMI, median hospital stay was shorter with PTA/S than bypass (9 vs 14 days, P<0.001).
“Length of stay was shorter after PTA/S than bypass (Median (range) 9 (0–104) vs 14 (1–127) days, P <.001).”
Quote in the paperNot a substantial claim - Findingown data
For CMI, home discharge occurred more often after PTA/S than bypass (87% vs 79%, P<0.01).
“Discharge to home was more common after PTA/S vs bypass (87% vs 79%, P <.01).”
Quote in the paperNot a substantial claim - Findingown data
For AMI, bowel resection was performed in 28% of PTA/S cases and 37% of bypass cases (P<0.05).
“Bowel resection occurred in 28% of patients undergoing PTA/S and 37% of those undergoing bypass ( P <.05).”
Quote in the paperNot a substantial claim - Findingown data
When limiting AMI comparison to PTA/S vs bypass, mortality was still significantly lower with PTA/S (P<0.001).
“When limiting the comparison of PTA/S to bypass, mortality was still significantly lower with PTA/S (P <.001).”
Quote in the paperNot a substantial claim - Findingown data
For AMI, home discharge rates were similar after PTA/S and bypass (72% vs 68%, P=0.37).
“Discharge disposition was similar for PTA/S and bypass (Home 72% vs 68%, P =.37).”
Quote in the paperNot a substantial claim - Findingown data
In-hospital mortality after mesenteric revascularization was lower for PTA/S than bypass for CMI (3.7% vs 13%, P<0.01).
“Mortality was lower after PTA/S than bypass for both CMI (3.7% vs 13%, P<0.01) and AMI (16% vs 28%, P<0.01).”
- Also stated in: § CMI 2000–2006 · plain
“Mortality after PTA/S was significantly lower when limiting the comparison to bypass (13% P <.001)”
Quote in the paperSubstantial claim - Also stated in: § CMI 2000–2006 · plain
- Interpretationreasoning
The fall in AMI operations was mainly among embolectomy cases.
“The decline in surgical procedures for AMI appears to be primarily in those undergoing embolectomy.”
Quote in the paperNot a substantial claim - Interpretationcitation
This embolectomy decline is probably explained by greater anticoagulation use for arrhythmias like atrial fibrillation.
“This is likely due to an increasing utilization of anticoagulation for dysrhythmias such as atrial fibrillation.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [24] Miyasaka, 2005, Time trends of ischemic stroke incidence and mortality in patients diagnosed with first atrial fibrillation in 1980 to 2000: report of a community-based study, Stroke source
Not checked in the free run.
- Study design and conductown data
This bias was clearest in AMI, where advanced ischemia was more common among bypass patients than PTA/S patients.
“This is most evident in AMI where more patients with advanced ischemia underwent bypass than PTA/S.”
Quote in the paperSubstantial claim- The authors state this as an assumption: For AMI, bowel resection was assumed to indicate pre-existing ischemic extent rather than a revascularization complication.
- Study design and conductown data
The data lack anatomic information such as vessel count, lesion length, and stenosis versus occlusion, which could affect strategy and outcomes.
“We do not have anatomic details about number of vessels treated, lesion length, or stenosis versus occlusion which are likely to impact revascularization strategy and could impact outcome.”
Quote in the paperNot a substantial claim - Study design and conductown data
A strength is the study's large sample, drawn from a 20% sample of non-federal hospitals via discharge data.
“The large numbers in this study (20% sample of non-federal hospitals) obtained from hospital discharge data are the strength of the study.”
Quote in the paperSubstantial claim - Interpretationcitation
In AMI, bowel resection probably indicates ischemic severity at presentation, not a revascularization complication.
“Unlike CMI, the need for bowel resection with AMI likely reflects the severity of ischemia at the time of vascular consultation rather than a complication of revascularization.9, 10”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [9] Kougias, 2007, Determinants of mortality and treatment outcome following surgical interventions for acute mesenteric ischemia, J Vasc Surg source
Not checked in the free run.
- cites [10] Oldenburg, 2004, Acute mesenteric ischemia: a clinical review, Arch Intern Med source
Not checked in the free run.
- The authors state this as an assumption: For AMI, bowel resection was assumed to indicate pre-existing ischemic extent rather than a revascularization complication.
- Interpretationreasoning
Embolectomy's high mortality probably stems from absent collateral circulation in embolic disease.
“This is likely due to the lack of an established collateral circulation with embolization.”
Quote in the paperSubstantial claim - Interpretationown data
In AMI, PTA/S was associated with lower mortality even after adjustment for bowel resection.
“However, after controlling for the need for bowel resection, there was a lower mortality with PTA/S.”
Quote in the paperSubstantial claim- The authors state this as an assumption: For AMI, bowel resection was assumed to indicate pre-existing ischemic extent rather than a revascularization complication.
- Study design and conductreasoning
The data cannot establish the timing of bowel resection-whether at operation, second look, before revascularization, or as a complication.
“The inability to definitively state whether a bowel resection is done at the time of mesenteric operation, during a “second look” procedure, before revascularization, or as a complication of the mesenteric operation is one more limitation of the NIS database.”
Quote in the paperSubstantial claim - Premisecitation
Kougias et al's review of the largest CMI PTA/S series reported 3% 30-day mortality.
“They found a 30-day mortality rate of 3%, and a restenosis rate of 28% at a mean follow up of 2 years with 27% undergoing repeat PTA/S.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [15] Kougias, 2007, Management of chronic mesenteric ischemia, J Endovasc Ther source
Not checked in the free run.
- Premisecitation
AMI revascularization usually carries mortality above 50%.
“Revascularization for AMI is typically associated with mortality rates over 50%.1, 9–11”
- Also stated in: § Discussion · plain
“Mortality with revascularization for AMI is typically >50%. 1, 5, 9, 10”
Quote in the paperSubstantial claim0 of 4 sources checked- cites [1] Cho, 2002, Long-term outcome after mesenteric artery reconstruction: a 37-year experience, J Vasc Surg source
Not checked in the free run.
- cites [9] Kougias, 2007, Determinants of mortality and treatment outcome following surgical interventions for acute mesenteric ischemia, J Vasc Surg source
Not checked in the free run.
- cites [10] Oldenburg, 2004, Acute mesenteric ischemia: a clinical review, Arch Intern Med source
Not checked in the free run.
- cites [11] Park, 2002, Contemporary management of acute mesenteric ischemia: factors associated with survival, J Vasc Surg source
Not checked in the free run.
- Also stated in: § Discussion · plain
- Premisecitation
Derrow and colleagues, using the NIS, found in-hospital mortality of about 15% for CMI surgical revascularization.
“Derrow et al reported national outcomes for surgical revascularization of CMI from the Nationwide Inpatient Sample (NIS) revealing an in-hospital mortality of 15%.8”
- Also stated in: § Discussion · plain
“Derrow et al reviewed the NIS database for surgical revascularization of CMI from 1993–1997 and found a mortality rate of 14.7% which corresponds to our findings from a broader period using the same database.8”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [8] Derrow, 2001, The outcome in the United States after thoracoabdominal aortic aneurysm repair, renal artery bypass, and mesenteric revascularization, J Vasc Surg source
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- Also stated in: § Discussion · plain
- Premisecitation
A few small case series have reported PTA/S use in AMI.
“Several small case series have described using PTA/S for treatment of AMI.18–22”
Quote in the paperNot a substantial claim0 of 5 sources checked- cites [18] Wyers, 2007, Retrograde mesenteric stenting during laparotomy for acute occlusive mesenteric ischemia, J Vasc Surg source
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- cites [19] Demirpolat, 2007, Acute mesenteric ischemia: endovascular therapy, Abdom Imaging source
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- cites [20] Gartenschlaeger, 2008, Successful percutaneous transluminal angioplasty and stenting in acute mesenteric ischemia, Cardiovasc Intervent Radiol source
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- cites [21] Moyes, 2008, Intraoperative retrograde mesenteric angioplasty for acute occlusive mesenteric ischaemia: a case series, Eur J Vasc Endovasc Surg source
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- cites [22] Sonesson, 2008, Hybrid recanalization of superior mesenteric artery occlusion in acute mesenteric ischemia, J Endovasc Ther source
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- Premisecitation
At high-volume centers, CMI surgical revascularization has had operative mortality as high as 12%.
“Results from these relatively high volume centers of excellence have operative mortality up to 12%.1–7”
- Also stated in: § Discussion · plain
“Mortality from large series of open revascularization for CMI range from 0% to 12%.1–7, 13, 14”
Quote in the paperNot a substantial claim0 of 7 sources checked- cites [1] Cho, 2002, Long-term outcome after mesenteric artery reconstruction: a 37-year experience, J Vasc Surg source
Not checked in the free run.
- cites [2] Park, 2002, Current results of open revascularization for chronic mesenteric ischemia: a standard for comparison, J Vasc Surg source
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- cites [3] Jimenez, 2002, Durability of antegrade synthetic aortomesenteric bypass for chronic mesenteric ischemia, J Vasc Surg source
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- cites [4] Cunningham, 1991, Chronic visceral ischemia, Ann Surg source
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- cites [5] Johnston, 1995, Mesenteric arterial bypass grafts: early and late results and suggested surgical approach for chronic and acute mesenteric ischemia, Surgery source
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- cites [6] McAfee, 1992, Influence of complete revascularization on chronic mesenteric ischemia, Am J Surg source
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- cites [7] Foley, 2000, Revascularization of the superior mesenteric artery alone for treatment of intestinal ischemia, J Vasc Surg source
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- Also stated in: § Discussion · plain
- May combine two claims. 33
- The quote only partly states this claim. 1
- Classified as probably not a substantial claim. 8
May combine two claims.
Findingown dataCMI revascularization patients were generally older women with multiple comorbidities.
“For CMI, from 2000–2006, patients undergoing revascularization in general were older women with multiple comorbidities.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataBetween 2000 and 2006, most AMI patients underwent open surgery (64.5%) rather than PTA/S (35.5%), while CMI patients more often underwent PTA/S (61.9% vs 38.1%).
“Between 2000–2006, the majority of patients diagnosed with AMI underwent open surgery (64.5%) versus PTA/S (35.5%), while patients with chronic mesenteric ischemia more often were treated with PTA/S (61.9% vs 38.1%).”
Quote in the paperNot a substantial claimMay combine two claims. The quote only partly states this claim.
Findingown dataFor CMI, CHF and atrial fibrillation/flutter each more than doubled mortality risk.
“Comorbidities that were predictive of mortality included congestive heart failure (CHF) and atrial fibrillation/flutter with a greater than 2-fold increased risk for both.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataMortality for both CMI and AMI declined over the study period (trend P<0.001).
“Over time, there was an overall decrease in mortality for both CMI and AMI (Test of trend, P <.001) (Figure 3 and 4).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor AMI, mortality was highest for embolectomy at 49%, 28% for bypass, and 35% for endarterectomy.
“Mortality was highest for embolectomy at 49% and was 28% for bypass and 35% for endarterectomy.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor AMI, PTA/S use rose and exceeded bypass by 2002, yet open surgery as a whole remained more common through 2006.
“PTA/S for AMI has also increased and surpassed bypass in 2002 but has not surpassed all surgical procedures for AMI even in 2006.”
- Also stated in: § OVERALL · plain
“For AMI, PTA/S has surpassed bypass and embolectomy individually, but surgical revascularization in general remains the predominant treatment.”
Quote in the paperNot a substantial claim- Also stated in: § OVERALL · plain
May combine two claims.
Findingown dataAmong CMI patients undergoing bowel resection, in-hospital mortality was higher than in those without bowel resection for both PTA/S and bypass (PTA/S 25% vs 3.1%, bypass 54% vs 10%, P<0.001).
“this subgroup showed an increased in-hospital mortality for both repair types (54% and 25%).”
- Also stated in: § CMI 2000–2006 · plain
“Mortality in those undergoing bowel resection was significantly increased for all patients regardless of revascularization method compared to those without a bowel operation (PTA/S 25% vs 3.1%, P <.001 and bypass 54% vs 10%, P <.001).”
Quote in the paperNot a substantial claim- Also stated in: § CMI 2000–2006 · plain
May combine two claims.
Findingown dataOverall morbidity was lower after PTA/S than bypass for CMI (20% vs 38%, P<0.001), with significant differences in cardiac and respiratory complications.
“Overall morbidity was also lower after PTA/S compared to bypass (20% vs. 38%, P <.001) with significant differences in cardiac and respiratory complications (Table III).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn AMI, bypass more than doubled mortality risk, and bowel resection increased it more than 3.5-fold.
“Bypass was associated with a greater than 2-fold increased risk of mortality while the need for a bowel resection carried a greater than 3.5-fold increased risk.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataOverall revascularization for CMI increased over time, whereas revascularization for AMI changed relatively little.
“Overall revascularization for CMI has increased over time (Figure 1) while for AMI there has been relatively little change (Figure 2).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn AMI, bypass was associated with greater overall morbidity than PTA/S, including more cardiac and respiratory complications.
“For AMI, overall morbidity was higher after bypass compared to PTA/S (Table III). Specifically, cardiac and respiratory complications were again significantly higher.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFrom 2000 onward, mortality for both CMI and AMI was lower than before 2000 (CMI 8% vs 15%; AMI 30% vs 49%; P<0.001).
“After the year 2000, when endovascular therapy was more commonly utilized, the mortality after repair for either indication was significantly lower than prior to this time period (CMI 8% vs 15%, P <.001; AMI 30 % vs 49 %, P <.001).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor AMI, PTA/S patients had more comorbidities than open-repair patients, including hypertension, PVD, CAD, AF/flutter, and chronic renal failure.
“Those undergoing PTA/S for AMI also had higher rates of comorbidities compared to those undergoing open surgical repair including hypertension, peripheral vascular disease, coronary artery disease, atrial fibrillation/flutter, and chronic renal failure (Table I).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataPTA/S use for CMI increased over time, surpassing all surgery for CMI by 2002 and more than doubling it by 2005.
“PTA/S increased steadily over time surpassing all surgery for CMI in 2002.”
- Also stated in: § OVERALL · plain
“PTA/S increased over time for both diagnoses and surpassed surgery for CMI by 2002 and more than doubled it by 2005.”
Quote in the paperSubstantial claim- Also stated in: § OVERALL · plain
May combine two claims.
Findingown dataAfter adding comorbidities to the AMI model, bowel resection and AF/flutter remained significant mortality predictors.
“With comorbidities included, the need for a bowel resection and atrial fibrillation/flutter were also significant predictors.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn CMI from 2000-2006, PTA/S patients were older, more often male, and had more comorbidities than surgical patients.
“However, those undergoing PTA/S were older, more likely male, and had higher rates of comorbidities (Table I).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataAF/flutter prevalence fell from a peak of 38% in 1994 to 24% in 2006.
“Of note, the proportion of patients with atrial fibrillation or atrial flutter decreased over time from a maximum or 38% in 1994 to 24% in 2006.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn AMI multivariate analysis, age and bypass (vs PTA/S) predicted mortality.
“Multivariate predictors of mortality for AMI included bypass vs PTA/S and age (Table IV).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn AMI, open repair showed a nonsignificant trend toward lower male mortality (34% vs 41%, P=0.07), while PTA/S mortality was similar by gender (16% vs 15%, P=0.85).
“There was a trend for males to have a lower mortality than females after open repair (34% vs 41%, P =.07), however mortality by gender was similar after PTA/S (16% vs 15%, P =.85).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataCMI surgery was mostly bypass (93%), with endarterectomy (4%) and embolectomy (3%) uncommon.
“The surgical procedure performed for CMI was overwhelmingly bypass (93%) compared to endarterectomy (4%) or embolectomy (3%).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor AMI, bowel resection during the admission raised mortality for both bypass (45% vs 17%) and PTA/S (29% vs 11%) (P<0.001).
“Mortality was again increased for both groups when bowel resection was performed during the same admission (Bypass 45% vs 17%, P <.001; PTA/S 29% vs 11%, P <.001).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataAmong AMI surgical cases in 2000-2006, embolectomy accounted for 49%, bypass 44%, and endarterectomy 7%.
“Surgical revascularization for AMI consisted of 49% embolectomy, 44% bypass, and 7% endarterectomy.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductreasoningUnmeasured variables besides bowel resection may have influenced whether bypass or PTA/S was chosen.
“There may have been other factors in addition to the need for bowel resection that were unmeasured that impacted the decision to choose bypass rather than PTA/S.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataAdministrative discharge databases like the NIS can contain coding errors.
“However, discharge databases such as NIS are subject to coding errors.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).
InterpretationreasoningPTA/S should not eliminate the need to assess bowel viability.
“However, PTA/S would not be expected to obviate the need to inspect bowel viability.”
Quote in the paperNot a substantial claim- Rests on an assumption: For most AMI cases, bowel viability must be assessed and resection performed if needed.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataRepeat mesenteric procedures could not be identified in the data.
“We also cannot identify patients undergoing repeat mesenteric procedures.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataBecause bypass patients much more often required resection, the groups differ and the comparison likely favors PTA/S.
“Given that resection was required in a much larger proportion of those undergoing bypass it is likely that the two cohorts are dissimilar and this biases the comparison in favor of PTA/S.”
Quote in the paperSubstantial claim- The authors state this as an assumption: For AMI, bowel resection was assumed to indicate pre-existing ischemic extent rather than a revascularization complication.
May combine two claims.
Study design and conductreasoningMore endovascular procedures may reflect repeats or incomplete workup, potentially biasing mortality toward PTA/S.
“The increasing number of endovascular procedures may be reflective of either of these and bias mortality in favor of PTA/S.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenCMI diagnosis is often challenging and may occur without full workup, especially before percutaneous treatment.
“Additionally, the diagnosis of CMI is often a difficult one and may be made without a complete workup particularly when percutaneous therapy is attempted.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataThis study's data more accurately represent the real risk of open CMI revascularization and show PTA/S's potential advantage.
“Therefore, the numbers from the current study better reflect the true risk of open surgical revascularization and demonstrate the potential benefit of PTA/S.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataThis was a retrospective analysis with obvious treatment-selection bias.
“This is a retrospective study with clear selection bias in the choice of therapy.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataFor AMI, the higher bowel-resection rate among bypass patients suggests more advanced ischemia in that group, complicating comparison with PTA/S.
“The greater proportion of patients undergoing bowel resection with bypass for AMI suggests a more advanced level of ischemia in this group making comparison with PTA/S difficult.”
Quote in the paperSubstantial claim- The authors state this as an assumption: For AMI, bowel resection was assumed to indicate pre-existing ischemic extent rather than a revascularization complication.
May combine two claims.
PremisecitationSmaller CMI PTA/S series have reported mortality sometimes similar to and sometimes lower than surgery.
“There has been an increasing number of small reports of the use of angioplasty with or without stenting (PTA/S) for treatment of CMI with mortality rates similar to surgery in some reports and lower than surgery in others.12–17”
Quote in the paperSubstantial claim0 of 6 sources checked- cites [12] Brown, 2005, Mesenteric stenting for chronic mesenteric ischemia, J Vasc Surg source
Not checked in the free run.
- cites [13] Atkins, 2007, Surgical revascularization versus endovascular therapy for chronic mesenteric ischemia: a comparative experience, J Vasc Surg source
Not checked in the free run.
- cites [14] Kasirajan, 2001, Chronic mesenteric ischemia: open surgery versus percutaneous angioplasty and stenting, J Vasc Surg source
Not checked in the free run.
- cites [15] Kougias, 2007, Management of chronic mesenteric ischemia, J Endovasc Ther source
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- cites [16] Lee, 2008, Long-term outcomes of endoluminal therapy for chronic atherosclerotic occlusive mesenteric disease, Ann Vasc Surg source
Not checked in the free run.
- cites [17] Sarac, 2008, Endovascular treatment of stenotic and occluded visceral arteries for chronic mesenteric ischemia, J Vasc Surg source
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
PremisecitationA Mayo Clinic study reported more anticoagulation and fewer embolic strokes in AF patients from 1980 to 2000.
“A recent study from the Mayo clinic found an increase in rates of anticoagulation and a decrease in embolic strokes in patients with atrial fibrillation between 1980–2000.24”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [24] Miyasaka, 2005, Time trends of ischemic stroke incidence and mortality in patients diagnosed with first atrial fibrillation in 1980 to 2000: report of a community-based study, Stroke source
Not checked in the free run.
May combine two claims.
Premiseown dataThe NIS samples 20% of all-payer hospital stays and includes weights for stratified national estimates.
“The database is a 20% all-payer sample of hospital stays and contains sampling weights to allow for stratified calculation of total population estimates.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataThe day-of-operation field was rarely recorded and could not reliably clarify resection timing.
“There is a variable for day of operation, but this was infrequently recorded and thus was an unreliable method to further clarify this.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationPTA/S is known to carry higher risks of restenosis and symptom recurrence.
“Finally, it is well documented that PTA/S is associated with a greater risk of restenosis and recurrent symptoms.15”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [15] Kougias, 2007, Management of chronic mesenteric ischemia, J Endovasc Ther source
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
PremisecitationThat review also reported 28% restenosis at 2 years and 27% repeat PTA/S.
“They found a 30-day mortality rate of 3%, and a restenosis rate of 28% at a mean follow up of 2 years with 27% undergoing repeat PTA/S.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [15] Kougias, 2007, Management of chronic mesenteric ischemia, J Endovasc Ther source
Not checked in the free run.
The paper relies on this without support.
Whether PTA/S has been widely adopted nationally for CMI and AMI is not known.
“The national adoption of PTA/S for CMI and AMI is largely unknown.”
The paper relies on this without support.
Whether PTA/S lowers short-term mortality relative to surgery remains uncertain.
“Additionally, it is unclear if there is a short term mortality benefit with PTA/S compared to surgery.”
The authors state this as an assumption.
For AMI, bowel resection was assumed to indicate pre-existing ischemic extent rather than a revascularization complication.
“The need for a bowel resection was included as an independent predictor variable in analysis of AMI (but not CMI) since this was felt more likely to be a reflection of the pre-existing extent of ischemia at the time of revascularization rather than a complication of the revascularization procedure.”
The paper relies on this without support.
Most practitioners regard PTA/S as unsuitable for most embolic cases.
“Since PTA/S is felt by most to be inappropriate treatment for most cases of embolism we focused on comparison of PTA/S with bypass.”
The paper relies on this without support.
For most AMI cases, bowel viability must be assessed and resection performed if needed.
“There is general agreement that in most cases of AMI there is a need to inspect the bowel viability and perform resection as needed.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
All studies have shown a benefit for endovascular therapy compared to open surgery in terms of lower bowel resection rates and lower 30-day mortality rates.
“All studies have shown a benefit for endovascular therapy compared to open surgery in terms of lower bowel resection rates and lower 30-day mortality rates.”
From Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery. (2022) · cites this paper as [107]
The Results report lower bowel-resection rates and lower in-hospital mortality after PTA/S than open surgery in this study. They do not report 30-day mortality. The Introduction also says earlier reports found mortality similar to surgery in some cases, so this paper does not support the claim that all studies showed a benefit. (LLM, conf=0.88)
Experimental — accuracy not yet measuredEndovascular therapy for acute mesenteric ischemia has escalated dramatically at most institutions and has been associated with lower mortality than traditional open surgery.
“Over the last decade, the use of endovascular therapy for treatment of patients with AMI has escalated dramatically at most institutions and has been associated with lower mortality than traditional open surgical therapy.4,5”
From Revascularization for acute mesenteric ischemia (2012) · cites this paper as [5]
Schermerhorn and associates reported that 35% of patients with acute mesenteric ischemia underwent angioplasty and stenting, while 65% were treated with open surgery, with mortality rates of 16% for endovascular versus 39% for traditional revascularization (P < .001).
“Schemmerhorn and associates evaluated the Nationwide Inpatient Sample from 1988 to 2006 and reported that 35% of patients presenting with AMI underwent angioplasty and stenting, while only 65% were treated with embolectomy, surgical bypass, or endarterectomy.5”
From Revascularization for acute mesenteric ischemia (2012) · cites this paper as [5]
Our findings in perioperative course associated with mortality are consistent with other published studies despite the fact that only patients in clinically advanced stages with indication for laparotomy were included.
“Our findings in perioperative course associated with mortality are consistent with other published studies despite the fact that only patients in clinically advanced stages with indication for laparotomy were included [8–11, 14, 25, 26].”
From Results after intraoperative open and endovascular revascularization of acute mesenteric ischemia requiring a laparotomy (2023) · cites this paper as [14]
Schermerhorn et al. found that mainly elderly patients with high comorbidities of cardiovascular diseases were affected by AMI and identified age and atrial fibrillation as predictors of poor survival.
“Consistent with our results, Schermerhorn et al. evaluated in the so far largest data analyses from the Nationwide Inpatient Sample (NIS), that mainly elderly patients with high comorbidities of cardiovascular diseases were affected by AMI and identified also age and atrial fibrillation as a predictor of poor survival [14].”
From Results after intraoperative open and endovascular revascularization of acute mesenteric ischemia requiring a laparotomy (2023) · cites this paper as [14]
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“3) 2 (1) 0 1 0 1 (5) 1 Pulmonary complications 2 (0.”
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“The advances in visceral imaging have been associated with a dramatic increase in the endovascular treatment of CMI, presumably because of earlier diagnosis, better understanding of the underlying disease process, and the less invasive nature of the endovascular approach.(3,4) Zettervall et al(4) reported from the Nat…”
BackgroundMethodAcosta, S. (2015) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000189 · Cited by 111 · see citing works
Oderich, G. S., Tallarita, T., Gloviczki, P., Duncan, A. A., Kalra, M., Misra, S., Cha, S., & Bower, T. C. (2012) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2011.10.122 · Cited by 102 · see citing works
ACR appropriateness criteria® imaging of mesenteric ischemia
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“many case series have been reported concerning surgical revascularisation for the treatment of CGI. Although many controversies remain on the choice of bypass route, antegrade versus retrograde, choice of conduit, use of vein versus prosthetic graft, and whether one or more vessels should be revascularised in the pres…”
BackgroundTrends in treatment and mortality for mesenteric ischemia in the United States from 2000 to 2012
Zettervall, S. L., Lo, R. C., Soden, P. A., Deery, S. E., Ultee, K. H., Pinto, D. S., Wyers, M. C., & Schermerhorn, M. L. (2017) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2017.01.007 · Cited by 88 · see citing works
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“Many groups have noted a reduced early mortality when endovascular techniques are used.(36,52) As with many endovascular techniques, the reduced early complication rate and mortality reduction comes with reduced longterm durability and increased need for reintervention.”
BackgroundContemporary Management of Acute Mesenteric Ischemia in the Endovascular Era
Lim, S., Halandras, P. M., Bechara, C. F., Aulivola, B., & Crisostomo, P. R. (2018) · Vascular and Endovascular Surgery · doi:10.1177/1538574418805228 · Cited by 92 · see citing works
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Hybrid Open Endovascular Technique for Aortic Thoracoabdominal Pathologies
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Open or percutaneous revascularization for chronic splanchnic syndrome
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Chronic Mesenteric Ischemia: Diagnosis and Management
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“Bar graph of mortality rates for surgery and endovascular treatmen of CMI taken from the National Inpatient Sample database.(7) LOS indicates length of stay.”
BackgroundMethodClinical management of chronic mesenteric ischemia
van Dijk, L. J. D., van Noord, D., de Vries, A. C., Kolkman, J. J., Geelkerken, R. H., Verhagen, H. J. M., Moelker, A. D., & Bruno, M. J. (2018) · United European Gastroenterology Journal · doi:10.1177/2050640618817698 · Cited by 82 · see citing works
Endovascular Therapy as a Primary Revascularization Modality in Acute Mesenteric Ischemia
Kärkkäinen, J. M., Lehtimäki, T. T., Saari, P., Hartikainen, J., Rantanen, T., Paajanen, H., & Manninen, H. (2015) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-015-1064-9 · Cited by 77 · see citing works
The importance of open emergency surgery in the treatment of acute mesenteric ischemia
Duran, M., Pohl, E., Grabitz, K., Schelzig, H., Sagban, T. A., & Simon, F. (2015) · World Journal of Emergency Surgery · doi:10.1186/s13017-015-0041-6 · Cited by 76 · see citing works
“Three other multicenter studies were national supra-regional studies: lower rates of bowel resection and lower mortality and morbidity were seen in these studies for the endovascular method [21, 22].”
Raupach, J., Lojík, M., Chovanec, V., Renc, O., Strýček, M., Dvorak, P., Hoffmann, P., Guňka, I., Ferko, A., Ryška, P., et al. (2015) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-015-1156-6 · Cited by 71 · see citing works
Chronic Mesenteric Ischemia: Endovascular Versus Open Revascularization
Gupta, P. K., Horan, S. M., Turaga, K. K., Miller, W. J., & Pipinos, I. I. (2010) · Journal of Endovascular Therapy · doi:10.1583/09-2935.1 · Cited by 63 · see citing works
Surgical management of peritonitis secondary to acute superior mesenteric artery occlusion
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Pillai, A. K., Kalva, S. P., Hsu, S. L., Walker, T. G., Silberzweig, J. E., Annamalai, G., Baerlocher, M. O., Mitchell, J. W., Midia, M., Nikolic, B., et al. (2018) · Journal of Vascular and Interventional Radiology · doi:10.1016/j.jvir.2017.11.024 · Cited by 58 · see citing works
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Results of Single- and Two-Vessel Mesenteric Artery Stents for Chronic Mesenteric Ischemia
Malgor, R. D., Oderich, G. S., McKusick, M. A., Misra, S., Kalra, M., Duncan, A. A., Bower, T. C., & Gloviczki, P. (2010) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2010.07.001 · Cited by 58 · see citing works
Duplex velocity criteria for native celiac/superior mesenteric artery stenosis vs in-stent stenosis
AbuRahma, A. F., Mousa, A. Y., Stone, P. A., Hass, S. M., Dean, L. S., & Keiffer, T. (2012) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2011.10.086 · Cited by 55 · see citing works
AbuRahma, A. F., Campbell, J. E., Stone, P. A., Hass, S. M., Mousa, A. Y., Srivastava, M., Nanjundappa, A., Dean, L. S., & Keiffer, T. (2013) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2012.10.082 · Cited by 56 · see citing works
Evolution in the Presentation, Treatment, and Outcomes of Patients with Acute Mesenteric Ischemia
Chou, E. L., Wang, L. J., McLellan, R. M., Feldman, Z. M., Latz, C. A., LaMuraglia, G. M., Clouse, W. D., Eagleton, M. J., & Conrad, M. F. (2021) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2021.01.116 · Cited by 51 · see citing works
Eslami, M. H., Rybin, D. V., Doros, G. D., McPhee, J. T., & Farber, A. M. (2015) · Vascular · doi:10.1177/1708538115577730 · Cited by 54 · see citing works
“In this regard, this study strives to evaluate if higher utilization of endovascular technology corresponded to a trend in decreasing mortality as it was previously suggested.(8)”
BackgroundResultInfluentialSurgical or Endovascular Treatment for Chronic Mesenteric Ischemia: A Multicenter Study
Rawat, N., & Gibbons, C. P. (2010) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2010.05.007 · Cited by 52 · see citing works
Outcomes of antegrade and retrograde open mesenteric bypass for acute mesenteric ischemia
Scali, S. T., Ayo, D., Giles, K. A., Gray, S. E., Kubilis, P. S., Back, M. R., Fatima, J., Arnaoutakis, D. J., Berceli, S. A., Beck, A. W., et al. (2018) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2018.04.063 · Cited by 52 · see citing works
“Although there are a variety of causes of AMI, the optimal revascularization strategy is unclear and several reports document increasing adoption of endovascular strategies (including hybrid repair; eg, retrograde open mesenteric stent) owing to the significant mortality of open mesenteric bypass (OMB).(3,8,9,12-15) H…”
BackgroundSelf-citationSalsano, G., Salsano, A., Sportelli, E., Petrocelli, F., Dahmane, M., Spinella, G., Pane, B., Mambrini, S., Palombo, D., & Santini, F. (2018) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-017-1749-3 · Cited by 52 · see citing works
“[7] that compared SG versus EV for treatment of acute and chronic mesenteric ischemia was excluded from the present review because of critical points that suggest problems in patients selection via ICD9-CM: (1) The number of patients included in the study is incongruous compared with the two other papers derived from…”
Pisimisis, G. T., & Oderich, G. S. (2010) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2010.04.004 · Cited by 49 · see citing works
Moulakakis, K. G., Mylonas, S., Antonopoulos, C. N., et al. (2012) · PubMed · doi:10.3978/j.issn.2225-319x.2012.08.02 · Cited by 48 · see citing works
“Because fewer than 40% of patients with large untreated TAAAs survive beyond three years, an operative approach is indicated with an encouraging life expectancy (1,2).”
BackgroundAcute mesenteric ischemia (Part II) – Vascular and endovascular surgical approaches
Kärkkäinen, J. M., & Acosta, S. (2017) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2016.11.003 · Cited by 48 · see citing works
Hogendoorn, W., Hunink, M. G. M., Schlösser, F. J. V., Moll, F. L., Muhs, B. E., & Sumpio, B. E. (2014) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2014.03.009 · Cited by 46 · see citing works
Bulut, T., Oosterhof-Berktas, R., Geelkerken, R. H., Brusse-Keizer, M., Stassen, E. J., & Kolkman, J. J. (2017) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2016.12.036 · Cited by 46 · see citing works
Systematic review and meta-analysis of endovascular treatment for acute mesenteric ischaemia
El Farargy, M., Abdel Hadi, A., Abou Eisha, M., Bashaeb, K., & Antoniou, G. A. (2017) · Vascular · doi:10.1177/1708538116689353 · Cited by 43 · see citing works
“9%, respectively.(3,4,17) Heterogeneity in study populations may account for such discrepancies in mortality rates.”
BackgroundMethodResultInfluentialChronic Mesenteric Ischemia: 20 Year Experience of Open Surgical Treatment
Lejay, A., Georg, Y., Tartaglia, E., Creton, O., Lucereau, B., Thaveau, F., Geny, B., & Chakfe, N. (2015) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2015.01.004 · Cited by 43 · see citing works
Mid-term outcome of endovascular revascularization for chronic mesenteric ischaemia
Dias, N. V., Acosta, S., Resch, T., Sonesson, B., Alhadad, A., Malina, M., & Ivancev, K. (2010) · Journal of British Surgery · doi:10.1002/bjs.6819 · Cited by 43 · see citing works
Endovascular therapy for acute mesenteric ischemia: an NSQIP analysis
Branco, B. C., Montero-Baker, M. F., Aziz, H., Taylor, Z., & Mills, J. L. (2015) · The American Surgeon™ · doi:10.1177/000313481508101131 · Cited by 43 · see citing works
Chronic mesenteric ischaemia: 28-year experience of endovascular treatment
Turba, U. C., Saad, W. E. A., Arslan, B., Sabri, S. S., Trotter, S. A., Angle, J. F., Hagspiel, K. D., Kern, J. A., Cherry, K. J., & Matsumoto, A. H. (2012) · European Radiology · doi:10.1007/s00330-011-2376-z · Cited by 40 · see citing works
“However, the use of endovascular treatment has rapidly grown and is now being used more often than open surgery [1].”
BackgroundNewton, W. B., Sagransky, M. J., Andrews, J. S., Hansen, K. J., Corriere, M. A., Goodney, P. P., & Edwards, M. S. (2011) · The American Surgeon · doi:10.1177/000313481107700715 · Cited by 40 · see citing works
Erben, Y., Protack, C. D., Jean, R. A., Sumpio, B. J., Miller, S. M., Liu, S., Trejo, G., & Sumpio, B. E. (2018) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2017.11.078 · Cited by 40 · see citing works
“This correlates with the significant improvement also noted by other colleagues in the United States and in Europe since the introduction of endovascular techniques, from a survival of <50% up to 67%.(16,29,30) Our study takes it a step further and investigates the LOS and the health care costs of this population of p…”
ResultChronic atherosclerotic mesenteric ischemia (CMI)
Zeller, T., Rastan, A., & Sixt, S. (2010) · Vascular Medicine · doi:10.1177/1358863x10372437 · Cited by 38 · see citing works
“001; Table 3).(31) In addition, bowel resection was less frequently encountered in the endovascular group than in the surgical group treated for CMI (3% vs 7%, p < 0.”
BackgroundNajdawi, M., Garzelli, L., Nuzzo, A., Huguet, A., Raynaud, L., Paulatto, L., Panis, Y., Ben Abdallah, I., Castier, Y., Sibert, A., et al. (2022) · European Radiology · doi:10.1007/s00330-022-08660-3 · Cited by 38 · see citing works
“This study even suggests that the number of surgical revascularizations is slowly decreasing over time [20].”
BackgroundACR Appropriateness Criteria ® Radiologic Management of Mesenteric Ischemia
Fidelman, N. A., AbuRahma, A. F., Cash, B. D., Kapoor, B. S., Knuttinen, M. G., Minocha, J., Rochon, P. J., Shaw, C. M., Ray, C. E., & Lorenz, J. M. (2017) · Journal of the American College of Radiology · doi:10.1016/j.jacr.2017.02.014 · Cited by 37 · see citing works
Ryer, E. J., Oderich, G. S., Bower, T. C., Macedo, T. A., Vrtiska, T. J., Duncan, A. A., Kalra, M., & Gloviczki, P. (2011) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2011.01.054 · Cited by 36 · see citing works
Sana, A., Vergouwe, Y., van Noord, D., Moons, L. M. G., Pattynama, P. M. T., Verhagen, H. J. M., Kuipers, E. J., & Mensink, P. (2010) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2010.11.006 · Cited by 36 · see citing works
The role of endovascular therapy in acute mesenteric ischemia
Ierardi, A. M. (2017) · Annals of Gastroenterology · doi:10.20524/aog.2017.0164 · Cited by 37 · see citing works
Chronic Mesenteric Ischemia: How to Select Patients for Invasive Treatment
Chandra, A., & Quiñones‐Baldrich, W. J. (2010) · Seminars in Vascular Surgery · doi:10.1053/j.semvascsurg.2009.12.003 · Cited by 36 · see citing works
Results of retrograde open mesenteric stenting for acute thrombotic mesenteric ischemia
Roussel, A., Schiava, N. D., Coscas, R., Pellenc, Q., Boudjelit, T., Goëau-Brissonnière, O., Corcos, O., Lermusiaux, P., Coggia, M., & Castier, Y. (2019) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2018.07.058 · Cited by 38 · see citing works
Mesenteric vascular treatment 2016: from open surgical repair to endovascular revascularization
Blauw, J. T. M., Bulut, T., Oderich, G. S., & Geelkerken, B. R. H. (2017) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2017.01.002 · Cited by 36 · see citing works
Hou, L., Wang, T., Wang, J., Zhao, J., & Yuan, D. (2022) · Vascular · doi:10.1177/17085381211024503 · Cited by 32 · see citing works
Management of Chronic Mesenteric Vascular Insufficiency: An Endovascular Approach
Schoch, D. M., LeSar, C. J., Joels, C. S., Erdoes, L. S., Sprouse, L. R., Fugate, M. W., Greer, M. S., Fisher, D. F., Mixon, H., Hogan, M. B., et al. (2011) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2010.12.043 · Cited by 31 · see citing works
Altintas, Ü., Lawaetz, M., de la Motte, L., Riazi, H., Lönn, L., Lindh, M., Sillesen, H., & Eiberg, J. (2021) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2021.01.003 · Cited by 33 · see citing works
Lemma, A. N., Tolonen, M., Vikatmaa, P., Mentula, P., Vikatmaa, L., Kantonen, I., Leppäniemi, A., & Sallinen, V. (2019) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2019.01.002 · Cited by 31 · see citing works
Lima, F. V., Kolte, D., Kennedy, K., Louis, D. W., Abbott, J., Soukas, P., Hyder, O., Mamdani, S. T., & Aronow, H. (2017) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2017.09.033 · Cited by 59 · see citing works
Ding, W., Wang, K., Liu, B., Fan, X., Wang, S., Cao, J., Wu, X., & Li, J. (2017) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000000799 · Cited by 31 · see citing works
“Duration of symptoms onset to treatment (h) 19 (3-37) 21 (6-41) 0.”
BackgroundBaker, A. C., Chew, V. W., Li, C., Lin, T.-C., Dawson, D. L., Pevec, W. C., & Hedayati, N. (2012) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2012.03.283 · Cited by 30 · see citing works
Mendes, B. C., Oderich, G. S., Tallarita, T., Kanamori, K. S., Kalra, M., DeMartino, R. R., Shuja, F., & Johnstone, J. K. (2018) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2017.12.076 · Cited by 32 · see citing works
Endovascular Versus Surgical Revascularization for the Management of Chronic Mesenteric Ischemia
Saedon, M. H., Saratzis, A. N., Karim, A., & Goodyear, S. (2015) · Vascular and Endovascular Surgery · doi:10.1177/1538574415585127 · Cited by 29 · see citing works
“Subsequently, 1 study was excluded because it provided outcomes for revascularization of patients presenting with acute ischemia, rather than chronic ischemia,(21) and 1 more study was excluded because it provided data on 17 patients treated between 1985 and 1990(22); 12 studies were subsequently included in the final…”
BackgroundChronic Mesenteric Ischemia: A Rare Cause of Chronic Abdominal Pain
Barret, M., Martineau, C., Rahmi, G., Pellerin, O., Sapoval, M. R., Alsac, J.-M., Fabiani, J., Malamut, G., Samaha, E., & Cellier, C. (2015) · The American Journal of Medicine · doi:10.1016/j.amjmed.2015.07.029 · Cited by 26 · see citing works
Median Arcuate Ligament Compression of the Mesenteric Vasculature
Tracci, M. C. (2014) · Techniques in vascular and interventional radiology · doi:10.1053/j.tvir.2014.12.007 · Cited by 29 · see citing works
Mesenteric ischemia: a radiologic perspective
Sinha, D., Kale, S. K., Kundaragi, N. G., & Sharma, S. (2020) · Abdominal Radiology · doi:10.1007/s00261-020-02867-y · Cited by 26 · see citing works
Acute mesenteric ischemia in elderly patients
Kärkkäinen, J. M. (2016) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2016.1212657 · Cited by 28 · see citing works
Open and endovascular management of acute mesenteric ischaemia: a systematic review
Murphy, B., Dejong, C. H. C., & Winter, D. C. (2019) · World Journal of Surgery · doi:10.1007/s00268-019-05149-x · Cited by 27 · see citing works
Modern Fixed Imaging Systems Reduce Radiation Exposure to Patients and Providers
Stangenberg, L., Shuja, F., van der Bom, I. M. J., van Alfen, M., Hamdan, A. D., Wyers, M. C., Guzman, R. J., & Schermerhorn, M. L. (2017) · Vascular and Endovascular Surgery · doi:10.1177/1538574417742211 · Cited by 27 · see citing works
“Virtually, every analysis of trends in utilization shows that the endovascular approach has become the dominant one.(2-4,13,14) This shift comes with increased use of fluoroscopic imaging as a requirement for endovascular diagnosis and therapy.”
BackgroundSelf-citationArya, S., Kingman, S., Knepper, J. P., Eliason, J. L., Henke, P. K., & Rectenwald, J. E. (2015) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2015.07.038 · Cited by 26 · see citing works
Chronic mesenteric ischemia: Time to remember open revascularization
Keese, M. A. (2013) · World Journal of Gastroenterology · doi:10.3748/wjg.v19.i9.1333 · Cited by 26 · see citing works
Current Concepts in the Management of Chronic Mesenteric Ischemia
Oderich, G. S. (2010) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-010-0061-1 · Cited by 26 · see citing works
Zhou, Y., Ryer, E. J., Garvin, R. P., Pham, A., Irvan, J. L., Orlova, K. A., & Elmore, J. R. (2018) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2018.08.166 · Cited by 26 · see citing works
Endovascular Treatment of Chronic Arterial Mesenteric Ischemia: A changing perspective?
Gibbons, C. P., & Roberts, D. E. (2010) · Seminars in Vascular Surgery · doi:10.1053/j.semvascsurg.2009.12.006 · Cited by 25 · see citing works
A Shifting Trend Towards Endovascular Intervention in the Treatment of Acute Mesenteric Ischemia
Naazar, A. A., Omair, A., Chu, S. H., Keane, K. G., & Weber, D. G. (2021) · Cureus · doi:10.7759/cureus.18544 · Cited by 24 · see citing works
Acute Thrombotic Mesenteric Ischemia: Primary Endovascular Treatment in Eight Patients
Gagnière, J., Favrolt, G., Alfidja, A., Kastler, A., Chabrot, P., Cassagnes, L., Buc, E., Pezet, D., & Boyer, L. (2011) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-011-0212-0 · Cited by 24 · see citing works
“[34] suggested in a recent article that the mortality rate was lower after PTA than after surgical bypass for AMI (16 vs.”
BackgroundErben, Y., Jean, R. A., Protack, C. D., Chiu, A. S., Liu, S., Sumpio, B. J., Miller, S. M., & Sumpio, B. E. (2018) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2017.10.071 · Cited by 23 · see citing works
“0001 Median (IQR) 4 (2-8) 9 (6-16) 6 (3-10) <.”
Swerdlow, N. J., Varkevisser, R. R. B., Soden, P. A., Zettervall, S. L., McCallum, J. C., Li, C., Wyers, M. C., & Schermerhorn, M. L. (2019) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2019.05.024 · Cited by 22 · see citing works
Self-citationTendera, M., Aboyans, V., Bartelink, M.-L. E. L., Baumgärtner, I., Clement, D. L., Collet, J., Cremonesi, A., Carlo, M. D., Erbel, R. M., Fowkes, F. G. R., et al. (2012) · Revista Española de Cardiología · doi:10.1016/j.recesp.2011.11.007 · Cited by 22 · see citing works
Endovascular treatment of mesenteric ischemia
Hawkins, B. M., Khan, Z., Abu-Fadel, M. S., EXAIRE, J. E., Saucedo, J. F., & Hennebry, T. A. (2011) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.23098 · Cited by 21 · see citing works
“In patients with chronic mesenteric ischemia, nonrandomized data suggest that endovascular therapy reduces in-hospital complications and mortality while symptom relief and long-term patency are maintained [3,12].”
BackgroundShi, Y., Zhao, B., Zhou, Y., Chen, L., Su, H., & Gu, J. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.07.084 · Cited by 21 · see citing works
- Authors
- Schermerhorn, M. L., Giles, K. A., Hamdan, A. D., Wyers, M. C., & Pomposelli, F. B.
- Affiliations
- Beth Israel Deaconess Medical Center (US)
- Corresponding author
- Schermerhorn, Marc L.
- Venue
- Journal of Vascular Surgery
- Publisher
- Elsevier BV
- Published
- 2009-08
- Volume
- 50
- Issue
- 2
- Pages
- 341-348.e1
- ISSN
- 0741-5214 (ISSN-L)
- PMC
- PMC2716426
- OpenAlex
- W1995716148
- Cited by
- 311
- References
- 24
- Citations by year
- 2026: 5 · 2025: 12 · 2024: 10 · 2023: 13 · 2022: 16 · 2021: 15 · 2020: 21 · 2019: 23 · 2018: 20 · 2017: 41 · 2016: 17 · 2015: 26 · 2014: 21 · 2013: 19 · 2012: 14
- FWCI
- 17.53
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Vascular Surgery (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5t32hl007734-30)
- National Heart, Lung, and Blood Institute (T-32HL007734, T-32#5T32HL007734)
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
- Keywords
- mesenteric revascularization, chronic mesenteric ischemia, acute mesenteric ischemia, percutaneous transluminal angioplasty, stenting, bypass surgery, endarterectomy, embolectomy, in-hospital mortality, bowel resection, treatment trends, patient selection
- MeSH terms
- Endarterectomy, Humans, Mesenteric Vascular Occlusion, Outcome and Process Assessment, Health Care, United States, Vascular Surgical Procedures, Stents, Chi-Square Distribution, Logistic Models, Embolectomy, Angioplasty, Statistics, Nonparametric
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