A systematic review and meta-analysis of endovascular versus open surgical revascularization for chronic mesenteric ischemia
Open accessAbstract
Background Despite the enthusiasm for endovascular revascularization for chronic mesenteric ischemia (CMI), it is not clear if early benefits offset long-term patency rates. This systematic review aimed to provide an up-to-date comprehensive evidence synthesis evaluating the two approaches. Methods We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus through July 15, 2016, for studies that compared the endovascular with the open surgical approach for revascularization in CMI patients. We conducted a random-effects meta-analysis to pool outcomes of interest across studies. Results We included 100 observational studies (22 comparative, 78 noncomparative; 18,726 patients; mean age, 69 years). Open surgery was associated with a statistically significant increase in the risk of in-hospital complications (relative risk [RR], 2.2; 95% confidence interval [CI], 1.8-2.6) and a nonsignificant increase in mortality at 30 days (RR, 1.57; 95% CI, 0.84-2.93). Open surgery was associated with lower risk of 3-year recurrence rates (RR, 0.47; 95% CI, 0.34-0.66) and a similar 3-year survival. Data from noncomparative studies provided similar inferences. The quality of evidence was low. Conclusions Observational evidence suggests that the endovascular approach for revascularization in patients with CMI may offer better early outcomes than open surgery, although this effect may not be durable. Long-term mortality appears to be similar.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In a meta-analysis the crude early mortality rate following mesenteric bypass surgery was estimated to be 5.5% (95% CI 4.8-6.3%), which according to the authors may be an underestimate due to publication bias.
“However, in a meta-analysis the crude early mortality rate was estimated to be 5.5% (95% CI 4.8 e 6.3%), which according to the authors may be an underestimate due to publication bias.”
Open surgery was associated with an increased risk of in hospital complications compared with endovascular revascularisation (RR 2.19, 95% CI 1.84-2.60).
“A systematic review including 100 observational studies (18 726 patients) demonstrated that open surgery was associated with an increased risk of in hospital complications compared with endovascular revascularisation (relative risk [RR] 2.19, 95% CI 1.84 e 2.60), but not with 30 day mortality (RR 1.57, 95% CI 0.84 e 2.93).”
Open surgery was not associated with 30 day mortality compared with endovascular revascularisation (RR 1.57, 95% CI 0.84-2.93).
“A systematic review including 100 observational studies (18 726 patients) demonstrated that open surgery was associated with an increased risk of in hospital complications compared with endovascular revascularisation (relative risk [RR] 2.19, 95% CI 1.84 e 2.60), but not with 30 day mortality (RR 1.57, 95% CI 0.84 e 2.93).”
Compared with open surgical bypass, endovascular revascularisation is associated with decreased morbidity and mortality rates, length of stay, and convalescence time.
“Compared with open surgical bypass, endovascular revascularisation is associated with decreased morbidity and mortality rates, length of stay, and convalescence time.”
Open surgery was associated with a lower risk of three year symptom recurrence (RR 0.47, 95% CI 0.34-0.66).
“Open surgery was associated with a lower risk of three year symptom recurrence (RR 0.47, 95% CI 0.34 e 0.66) and a similar three year survival (RR 0.96, 95% CI 0.86 e 1.07).”
Open surgery was associated with a similar three year survival (RR 0.96, 95% CI 0.86-1.07).
“Open surgery was associated with a lower risk of three year symptom recurrence (RR 0.47, 95% CI 0.34 e 0.66) and a similar three year survival (RR 0.96, 95% CI 0.86 e 1.07).”
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859 · see citing works
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552 · see citing works
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763 · see citing works
(2014) · Medical Entomology and Zoology · Cited by 17,633 · see citing works
Closing the Gap between Methodologists and End-Users: <i>R</i> as a Computational Back-End
Wallace, B. C., Dahabreh, I. J., Trikalinos, T. A., Lau, J., Trow, P., & Schmid, C. H. (2012) · Journal of Statistical Software · doi:10.18637/jss.v049.i05 · Cited by 1,125 · cited 2× · see citing works
“Statistical analyses were conducted using OpenMeta[Analyst].(14) All values were two tailed, and a P < .”
MethodEditor's Choice – Management of the Diseases of Mesenteric Arteries and Veins
Björck, M., Koelemay, M., Acosta, S., Bastos Goncalves, F., Kölbel, T., Kolkman, J. J., Lees, T., Lefevre, J. H., Menyhei, G., Oderich, G., et al. (2017) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2017.01.010 · Cited by 658 · see citing works
Self-citationMesenteric revascularization: management and outcomes in the United States, 1988-2006
Schermerhorn, M. L., Giles, K. A., Hamdan, A. D., Wyers, M. C., & Pomposelli, F. B. (2009) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2009.03.004 · Cited by 311 · cited 2× · see citing works
“The advances in visceral imaging have been associated with a dramatic increase in the endovascular treatment of CMI, presumably because of earlier diagnosis, better understanding of the underlying disease process, and the less invasive nature of the endovascular approach.(3,4) Zettervall et al(4) reported from the Nat…”
BackgroundMethodMesenteric duplex scanning: A blinded prospective study
Moneta, G. L., Lee, R. W., Yeager, R. A., Taylor, L. M., & Porter, J. M. (1993) · Journal of Vascular Surgery · doi:10.1016/0741-5214(93)90011-a · Cited by 283 · see citing works
ACR appropriateness criteria® imaging of mesenteric ischemia
Oliva, I. B., Davarpanah, A. H., Rybicki, F. J., Desjardins, B., Flamm, S. D., Francois, C. J., Gerhard-Herman, M. D., Kalva, S. P., Ashraf Mansour, M., Mohler, E. R., et al. (2013) · Abdominal Imaging · doi:10.1007/s00261-012-9975-2 · Cited by 200 · see citing works
Open versus endovascular revascularization for chronic mesenteric ischemia: Risk-stratified outcomes
Oderich, G. S., Bower, T. C., Sullivan, T. M., Bjarnason, H., Cha, S., & Gloviczki, P. (2009) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2009.02.006 · Cited by 186 · see citing works
Endovascular treatment of stenotic and occluded visceral arteries for chronic mesenteric ischemia
Sarac, T. P., Altinel, O., Kashyap, V., Bena, J., Lyden, S., Sruvastava, S., Eagleton, M., & Clair, D. (2008) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2007.11.046 · Cited by 145 · see citing works
Chronic Mesenteric Ischemia: Critical Review and Guidelines for Management
Pecoraro, F., Rančić, Z., Lachat, M. L., Mayer, D., Amann-Vesti, B. R., Pfammatter, T., Bajardi, G., & Veith, F. J. (2012) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2012.05.012 · Cited by 127 · see citing works
Trends in treatment and mortality for mesenteric ischemia in the United States from 2000 to 2012
Zettervall, S. L., Lo, R. C., Soden, P. A., Deery, S. E., Ultee, K. H., Pinto, D. S., Wyers, M. C., & Schermerhorn, M. L. (2017) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2017.01.007 · Cited by 88 · see citing works
Tallarita, T., Oderich, G. S., Gloviczki, P., Duncan, A. A., Kalra, M., Cha, S., Misra, S., & Bower, T. C. (2013) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2012.09.047 · Cited by 83 · see citing works
Chronic Mesenteric Ischemia: Endovascular Versus Open Revascularization
Gupta, P. K., Horan, S. M., Turaga, K. K., Miller, W. J., & Pipinos, I. I. (2010) · Journal of Endovascular Therapy · doi:10.1583/09-2935.1 · Cited by 63 · see citing works
Cai, W., Li, X., Shu, C., Qiu, J. H., Fang, K., Li, M., Chen, Y., & Liu, D. (2015) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2015.01.010 · Cited by 55 · see citing works
Hogendoorn, W., Hunink, M. G. M., Schlösser, F. J. V., Moll, F. L., Muhs, B. E., & Sumpio, B. E. (2014) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2014.03.009 · Cited by 46 · see citing works
Outcomes of Endovascular and Open Treatment for Chronic Mesenteric Ischemia
Indes, J., Giacovelli, J. K., Muhs, B. E., Sosa, J. A., & Dardik, A. (2009) · Journal of Endovascular Therapy · doi:10.1583/09-2797.1 · Cited by 46 · see citing works
ACR Appropriateness Criteria ® Radiologic Management of Mesenteric Ischemia
Fidelman, N. A., AbuRahma, A. F., Cash, B. D., Kapoor, B. S., Knuttinen, M. G., Minocha, J., Rochon, P. J., Shaw, C. M., Ray, C. E., & Lorenz, J. M. (2017) · Journal of the American College of Radiology · doi:10.1016/j.jacr.2017.02.014 · Cited by 37 · see citing works
Chronic mesenteric ischemia outcome analysis and predictors of endovascular failure
Zacharias, N., Eghbalieh, S. D., Chang, B. B., Kreienberg, P. B., Roddy, S. P., Taggert, J. B., Sternbach, Y., & Darling, R. C. (2016) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2016.02.051 · Cited by 35 · see citing works
Endovascular Versus Surgical Revascularization for the Management of Chronic Mesenteric Ischemia
Saedon, M. H., Saratzis, A. N., Karim, A., & Goodyear, S. (2015) · Vascular and Endovascular Surgery · doi:10.1177/1538574415585127 · Cited by 29 · see citing works
Arya, S., Kingman, S., Knepper, J. P., Eliason, J. L., Henke, P. K., & Rectenwald, J. E. (2015) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2015.07.038 · Cited by 26 · see citing works
Ferro, C., Rossi, U. G., Seitun, S., Bovio, G., & Fornaro, R. (2012) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-012-0469-y · Cited by 12 · see citing works
Jain, G., Pandit, B. N., Goyal, M., & Trehan, V. (2013) · Cardiovascular Intervention and Therapeutics · doi:10.1007/s12928-013-0167-y · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
2024 ESC Guidelines for the management of peripheral arterial and aortic diseases
Mazzolai, L., Teixidó‐Turà, G., Lanzi, S., Boc, V., Bossone, E., Brodmann, M., Bura-Rivière, A., Backer, J. F. A. D., Déglise, S., Corte, A. D., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae179 · Cited by 1,222 · see citing works
Terlouw, L. G., Moelker, A. D., Abrahamsen, J., Acosta, S., Bakker, O. J., Baumgärtner, I., Boyer, L., Corcos, O., van Dijk, L. J. D., Duran, M., et al. (2020) · United European Gastroenterology Journal · doi:10.1177/2050640620916681 · Cited by 186 · see citing works
Chronic mesenteric ischemia: Clinical practice guidelines from the Society for Vascular Surgery
Huber, T. S., Björck, M., Chandra, A., Clouse, W. D., Dalsing, M. C., Oderich, G. S., Smeds, M. R., & Murad, M. H. (2021) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2020.10.029 · Cited by 152 · see citing works
Self-citationKoelemay, M. J., Geelkerken, R. H., Kärkkäinen, J., Leone, N., Antoniou, G. A., de Bruin, J. L., Gombert, A., Gottsätter, A., Iborra, E., Ronchey, S., et al. (2025) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2025.06.010 · Cited by 123 · see citing works
Self-citationReview Article: Mesenteric Ischemia
Gnanapandithan, K., & Feuerstadt, P. (2020) · Current Gastroenterology Reports · doi:10.1007/s11894-020-0754-x · Cited by 103 · see citing works
Miller, A. S., Boyce, K. M., Box, B., Clarke, M. D., Duff, S., Foley, N. M., Guy, R., Massey, L. H., Ramsay, G., Slade, D. A. J., et al. (2021) · Colorectal Disease · doi:10.1111/codi.15503 · Cited by 81 · see citing works
Clinical management of chronic mesenteric ischemia
van Dijk, L. J. D., van Noord, D., de Vries, A. C., Kolkman, J. J., Geelkerken, R. H., Verhagen, H. J. M., Moelker, A. D., & Bruno, M. J. (2018) · United European Gastroenterology Journal · doi:10.1177/2050640618817698 · Cited by 82 · see citing works
“A recently published meta-analysis included 100 observational studies to compare endovascular revascularization (10,679 patients) and open surgical revascularization (8047 patients).(12) Risk of in-hospital complications was significantly increased in the open surgical revascularization group (relative risk (RR) 2.”
BackgroundMethodChronic mesenteric ischemia: Diagnosis and management
Sardar, P., & White, C. J. (2021) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2021.03.002 · Cited by 48 · see citing works
Terlouw, L. G., Verbeten, M., van Noord, D., Brusse-Keizer, M., Beumer, R. R., Geelkerken, R. H., Bruno, M. J., Kolkman, J. J., & Dutch Mesenteric Ischemia Study Group (2020) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000200 · Cited by 39 · see citing works
“This study reports a higher incidence of atherosclerotic CMI and MALS in female patients and con fi rms the female predisposition reported by other studies (1,17,18).”
Terlouw, L. G., van Dijk, L. J. D., van Noord, D., Bakker, O. J., Bijdevaate, D. C., Erler, N. S., Fioole, B., Harki, J., van den Heuvel, D. A. F., Hinnen, J. W., et al. (2024) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(23)00402-8 · Cited by 34 · see citing works
Altintas, Ü., Lawaetz, M., de la Motte, L., Riazi, H., Lönn, L., Lindh, M., Sillesen, H., & Eiberg, J. (2021) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2021.01.003 · Cited by 33 · see citing works
Locatelli, F., Nana, P., Houérou, T. L., Guirimand, A., Nader, M., Gaudin, A., Bosse, C., Fabre, D., & Haulon, S. (2023) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2023.06.002 · Cited by 30 · see citing works
ACR Appropriateness Criteria® radiologic management of mesenteric ischemia: 2022 update
Lam, A., Kim, Y.-J., Fidelman, N., Higgins, M., Cash, B. D., Charalel, R. A., Guimaraes, M. S., Kwan, S. W., Patel, P. J., Plett, S., et al. (2022) · Journal of the American College of Radiology · doi:10.1016/j.jacr.2022.09.006 · Cited by 29 · see citing works
on behalf of the Dutch Mesenteric Ischemia Study group (DMIS), van Dijk, L. J. D., Harki, J., van Noord, D., Verhagen, H. J. M., Kolkman, J. J., Geelkerken, R. H., Bruno, M. J., & Moelker, A. D. (2019) · Trials · doi:10.1186/s13063-019-3609-8 · Cited by 24 · see citing works
Bordet, M., Tresson, P., Huvelle, U., Long, A., Passot, G., Bergoin, C., Lermusiaux, P., Millon, A., & Della Schiava, N. (2021) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2021.03.003 · Cited by 23 · see citing works
Direct Retrograde Bypass is Preferable to Antegrade Bypass for Open Mesenteric Revascularization
Huerta, C. T., Orr, N. T., Tyagi, S. C., Badia, D. J., Richie, C. D., & Endean, E. D. (2020) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2020.01.019 · Cited by 19 · see citing works
Early and Midterm Outcomes of Open and Endovascular Revascularization of Chronic Mesenteric Ischemia
Menges, A., Reutersberg, B., Busch, A., Salvermoser, M., Feith, M., Trenner, M., Kallmayer, M. A., Zimmermann, A., & Eckstein, H. (2020) · World Journal of Surgery · doi:10.1007/s00268-020-05513-2 · Cited by 17 · see citing works
Advancements in Treatment Strategies for Chronic Mesenteric Ischemia: A Comprehensive Review
Xhepa, G., Vanzulli, A., Sciacqua, L. V., Inzerillo, A., Faerber, P., Ierardi, A. M., Carrafiello, G., Grande, F. D., & Ricoeur, A. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12227112 · Cited by 16 · see citing works
“The most comprehensive and rigorous study examining the perioperative and long-term outcomes of patients with CMI treated with either open or endovascular approaches is the systematic review and meta-analysis conducted by Alahdab et al. [70].”
BackgroundRusso, M., Gurgoglione, F. L., Russo, A., Rinaldi, R., Triglia, L. T., Foschi, M., Vigna, C., Vergallo, R., Montone, R. A., Benedetto, U., et al. (2025) · Life · doi:10.3390/life15081226 · Cited by 20 · see citing works
“Along with sex, age, smoking, hypertension and dyslipidemia are the most important risk factors for mesenteric atherosclerosis [28].”
Brenner, D. M., Brandt, L. J., Fenster, M., Hamilton, M. J., Kamboj, A. K., Oxentenko, A. S., Wang, B., & Chey, W. D. (2022) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2022.09.022 · Cited by 14 · see citing works
A Systematic Review of Endovascular Repair Outcomes in Atherosclerotic Chronic Mesenteric Ischaemia
Nana, P., Koelemay, M. J. W., Leone, N., Brodis, A., van den Berg, J. C., de Bruin, J. L., Geelkerken, R. H., & Spanos, K. (2023) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2023.07.011 · Cited by 13 · see citing works
Mesenteric Artery Stenosis is a Risk Factor for Anastomotic Leakage in Colorectal Surgery
Harmankaya, D., Egberts, K. J. V., Metz, F. M., Vaassen, H. G. M., Petersman, S. S.-V. E., Brusse-Keizer, M. G. J., le Haen, P., Bruno, M. J., Geelkerken, B., & van Noord, D. (2024) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2024.11.013 · Cited by 12 · see citing works
Barnes, J. A., Columbo, J. A., Ponukumati, A. S., Zwolak, R. M., Olive, F. T., Goodney, P. P., Powell, R. J., & Zacharias, N. (2020) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2020.04.064 · Cited by 12 · see citing works
Surgical and endovascular revascularization of chronic mesenteric ischemia
Wolk, S., Kapalla, M., Ludwig, S., Radosa, C., Hoffmann, R.-T., Weitz, J., & Reeps, C. (2022) · Langenbeck's Archives of Surgery · doi:10.1007/s00423-022-02462-3 · Cited by 11 · see citing works
“Nevertheless, OT is still associated with higher morbidity, which could be expected owing to the extensive nature of the open procedure [7, 9, 21, 22].”
BackgroundInfluentialKrishnamurthy, G., Menon, A., Kannan, K., Prakash, S., Rajendran, A., & Philips, D. (2019) · Intractable & Rare Diseases Research · doi:10.5582/irdr.2019.01087 · Cited by 11 · see citing works
“Advances in endovascular techniques, expertise and stents have seen the gap between a morbid open revascularization and relatively safe endovascular revascularization being narrowed (18).”
BackgroundPatel, R. J., Cui, C., Khan, M. A., Willie-Permor, D., & Malas, M. B. (2023) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2023.02.013 · Cited by 9 · see citing works
Shavkuta, G. V. (2022) · South Russian Journal of Therapeutic Practice · doi:10.21886/2712-8156-2022-3-3-108-115 · Cited by 9 · see citing works
Obstructive Sleep Apnea and Cardiovascular Disease
Shitara, J., & Kasai, T. (2020) · Springer eBooks · doi:10.1007/978-3-030-42998-0_24 · Cited by 9 · see citing works
Mesenteric artery calcium scoring: a potential screening method for chronic mesenteric ischemia
Terlouw, L. G., van Noord, D., van Walsum, T., Bruno, M. J., & Moelker, A. D. (2020) · European Radiology · doi:10.1007/s00330-020-07530-0 · Cited by 8 · see citing works
Mitchell, E. L. (2020) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2020.11.018 · Cited by 9 · see citing works
Defining Duplex Ultrasound Criteria for In-Stent Restenosis of the Superior Mesenteric Artery
Green, J., Ryer, E. J., Borden, N., Ali, B., Garvin, R. P., Yang, A. E., Hashmi, A., Salzler, G. G., & Elmore, J. R. (2021) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2020.12.023 · Cited by 8 · see citing works
Terlouw, L. G., van Dijk, L. J. D., van Noord, D., Voogd, T., Bakker, B. J., Nikkessen, S., Bruno, M. J., & Moelker, A. D. (2022) · European Journal of Radiology · doi:10.1016/j.ejrad.2022.110316 · Cited by 8 · see citing works
Crawford, J. D., Scali, S. T., Khan, T., Back, M. R., Cooper, M. A., Arnaoutakis, D. K., Berceli, S. A., Upchurch, G. R., Huber, T. S., & Giles, K. A. (2021) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2021.03.039 · Cited by 8 · see citing works
Self-citationEarly Identification of Chronic Mesenteric Ischemia with Endoscopic Duplex Ultrasound
Safi, N., Ånonsen, K. V., Berge, S. T., Medhus, A. W., Sundhagen, J. O., Hisdal, J., & Kazmi, S. S. H. (2022) · Vascular Health and Risk Management · doi:10.2147/vhrm.s358570 · Cited by 7 · see citing works
“Other complaints may follow, such as diarrhea or constipation, nausea, vomiting, and in severe cases of ischemia, worsening abdominal pain even during exercise and activity.(7) However, these symptoms are poorly related to CMI.”
BackgroundKazmi, S. S. H., Safi, N., Berge, S. T., Kazmi, M., Sundhagen, J. O., Julien, K., Thorsby, P. M., Ånonsen, K. V., Medhus, A. W., & Hisdal, J. (2022) · Vascular Health and Risk Management · doi:10.2147/vhrm.s365625 · Cited by 7 · see citing works
Chronic mesenteric ischemia-induced intestinal dysbiosis resolved after revascularization
Munley, J. A., Nagpal, R., Hanson, N. C., Mirzaie, A., Laquian, L., Mohr, A. M., Efron, P. A., Arnaoutakis, D. J., & Cooper, M. A. (2023) · Journal of Vascular Surgery Cases, Innovations and Techniques · doi:10.1016/j.jvscit.2022.101084 · Cited by 8 · see citing works
“CMI is a devastating disease for which the standard of care with open or endovascular mesenteric revascularization can result in systemic inflammation and a morbid postoperative course.(2,3) In our study, we found that CMI induces intestinal dysbiosis, characterized by decreased alpha-diversity and a unique microbial…”
Chronic mesenteric ischemia: Diagnosis & management
Anandan, A. S., & Silva, M. (2022) · Annals of Medicine & Surgery · doi:10.1016/j.amsu.2022.104138 · Cited by 6 · see citing works
“The recommended imaging modality is duplex ultrasound obtained at 3–6 monthly intervals [15].”
MethodNatural history of superior mesenteric artery in-stent restenosis
Sorour, A. A., Dehaini, H., Alnahhal, K. I., Khalifeh, A., Rowse, J. W., Quatromoni, J. G., Caputo, F. J., Lyden, S. P., & Kirksey, L. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2023.11.035 · Cited by 6 · see citing works
Endovascular Management of Acute and Chronic Mesenteric Ischemia
Alonso, A. G., de Macedo, K. M., & Siracuse, J. J. (2025) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2025.04.105 · Cited by 7 · see citing works
Pamulapati, V., Guitart, J. R., Helenowski, I. B., Resnick, S., & Ho, K. J. (2021) · Vascular Medicine · doi:10.1177/1358863x211025615 · Cited by 6 · see citing works
Sultan, S., Acharya, Y., Mustafa, M. A. R., & Hynes, N. (2021) · Cureus · doi:10.7759/cureus.20726 · Cited by 6 · see citing works
“However, long-term mortality was similar with both approaches, while symptoms recurrence and reintervention rates were higher with the endovascular intervention [25,26].”
Survival, Reintervention, and Value of Open and Endovascular Repair for Chronic Mesenteric Ischemia
Lehane, D. J., Geiger, J. T., Zottola, Z. R., Newhall, K. A., Mix, D. S., Doyle, A. J., & Stoner, M. C. (2023) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2023.08.003 · Cited by 5 · see citing works
Traitement endovasculaire des angors mésentériques
Hammamia, M. B., Mrad, M. B., Hadhri, S. E., Tarzi, M., Miri, R., Ghédira, F., Derbel, B., Omrane, S. B., Kalfat, T., Ziadi, J., et al. (2019) · JMV-Journal de Médecine Vasculaire · doi:10.1016/j.jdmv.2019.06.001 · Cited by 5 · see citing works
Terlouw, L. G., van Noord, D., van Walsum, T., van Dijk, L. J. D., Moelker, A. D., & Bruno, M. J. (2021) · United European Gastroenterology Journal · doi:10.1002/ueg2.12102 · Cited by 5 · see citing works
“Weight loss and postprandial abdominal pain are typical presenting symptoms of CMI and CMI should always be considered in patients with one or both of these symptoms.(1,2) The current study confirmed the association between CMI and weight loss and CMI and postprandial abdominal pain.”
BackgroundOlson, K. A., & Teixeira, P. G. (2021) · Advances in Surgery · doi:10.1016/j.yasu.2021.05.006 · Cited by 6 · see citing works
Long-term value in open and endovascular repair of chronic mesenteric ischemia
Lehane, D. J., Geiger, J. T., Kedwai, B. J., Zottola, Z. R., Newhall, K. S., Mix, D., Doyle, A. J., & Stoner, M. C. (2023) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2023.09.003 · Cited by 4 · see citing works
Lai, C., Liu, H.-P., & Chang, W. (2024) · Medicine · doi:10.1097/md.0000000000041027 · Cited by 4 · see citing works
Bakoyiannis, C., Mylonas, K. S., Davakis, S., Tsaples, G., Karaolanis, G., & Liakakos, T. (2019) · Vascular · doi:10.1177/1708538119887567 · Cited by 4 · see citing works
“66) and similar three-year survival.(16) Importantly, the comparable long-term mortality rates likely imply that the perioperative survival benefit of the endovascular approach is negated by a higher mortality rate during follow-up (potentially because of the higher rate of recurrent symptoms and reinterventions in a…”
BackgroundResultIntravascular lithotripsy for the treatment of inferior mesenteric artery in-stent restenosis
Ratner, M., Muqri, F., & Garg, K. (2023) · Journal of Vascular Surgery Cases and Innovative Techniques · doi:10.1016/j.jvscit.2023.101254 · Cited by 4 · see citing works
Coco, D., & Leanza, S. (2020) · MAEDICA – a Journal of Clinical Medicine · doi:10.26574/maedica.2020.15.3.381 · Cited by 4 · see citing works
Jacobs, C. R., Scali, S. T., Jacobs, B. N., Filiberto, A. C., Anderson, E. M., Fazzone, B. J., Back, M. R., Upchurch, G. R., Giles, K. A., & Huber, T. S. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.03.028 · Cited by 3 · see citing works
Self-citationMesenteric ishemia: features of different methods of diagnosis and treatment
Kostenko, N. V., Isaeva, V. Y., Kushalakov, A. M., Mustafaev, Z. I., & Yanpolskiy, A. S. (2024) · ASTRAKHAN MEDICAL JOURNAL · doi:10.17021/1992-6499-2024-1-17-28 · Cited by 3 · see citing works
Management and outcomes of chronic mesenteric ischemia in older adults: A comprehensive review
Sudina, Y., Anan, H., Daher, J., & Chaer, R. A. (2025) · Seminars in Vascular Surgery · doi:10.1053/j.semvascsurg.2025.06.001 · Cited by 3 · see citing works
Surgical Intervention for Chronic Mesenteric Ischemia
Klein, A., Bennett, L. F., Ha, C. P., & Kirkwood, M. L. (2018) · Digestive Disease Interventions · doi:10.1055/s-0038-1668539 · Cited by 3 · see citing works
The gastric double-stripe sign of chronic mesenteric ischemia: A case report
Yamamoto, H., & Hashimoto, T. (2023) · Medicine · doi:10.1097/md.0000000000032842 · Cited by 3 · see citing works
“A large meta-analysis including 100 observational studies reported that an endovascular approach is associated with lower perioperative complication rates, shorter hospital stays, and lower costs compared to those of a surgical approach.[15] Although an endovascular approach has a higher restenosis rate, it has fewer…”
ResultSavlania, A., Vaddavalli, V. V., Abuji, K., Ravi, A., Maheshwari, N., Kaman, L., Behera, A., & Gorsi, U. (2023) · Indian Journal of Gastroenterology · doi:10.1007/s12664-023-01447-4 · Cited by 3 · see citing works
“Similarly, in a systemic review and meta-analysis, it was found that open revascularization was associated with an increased perioperative complication rate with no difference in 30-day mortality [18].”
Chronische mesenteriale Ischämie
Heiß, C. (2018) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/a-0585-8049 · Cited by 3 · see citing works
“[12] Alahdab F, Arwani R, Pasha AK et al.”
BackgroundChronic Mesenteric Ischemia in a Patient With Limited Systemic Sclerosis
Barasa, A., & Bader, G. A. (2023) · Cureus · doi:10.7759/cureus.34209 · Cited by 2 · see citing works
“Surgery is preferred for patients with a history of prior vascular complications, significant tortuosity or calcifications seen on imaging, or chronic mesenteric ischemia due to nonatherosclerotic causes or who have had a recurrence of stenosis despite multiple endovascular attempts at revascularization [13,14].”
BackgroundIncidence and predictors of gastrointestinal hemorrhage following mesenteric revascularization
Farazdaghi, A., Rodrigues, D. V. S., Cassianni, C. E., Colglazier, J. J., Oderich, G. S., Kalra, M., Shuja, F., Schaller, M. S., Rasmussen, T. E., DeMartino, R. R., et al. (2024) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2024.11.006 · Cited by 2 · see citing works
Fassler, M. J., Scali, S. T., Stinson, G. P., Fazzone, B. J., Jacobs, C. R., Jacobs, B. N., Neal, D., Back, M. R., & Huber, T. S. (2025) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2025.08.053 · Cited by 2 · see citing works
Self-citationFazzone, B. J., Scali, S. T., Albrecht, P., Anderson, E. M., Neal, D. W., Huber, T. S., & Endean, E. D. (2026) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2026.03.613 · Cited by 2 · see citing works
Self-citationZaitsev, O., Kopeykin, A. A., Surov, D. E., Surov, I., Yudin, V., Koshkina, A. V., & Kochetkov, F. (2024) · I P Pavlov Russian Medical Biological Herald · doi:10.17816/pavlovj303673
El-Qawaqzeh, K. W. M., Mateo, R. B., Chang, H., Goyal, A., Babu, S. C., & Ventarola, D. J. (2024) · Journal of Vascular Surgery Cases and Innovative Techniques · doi:10.1016/j.jvscit.2024.101699 · Cited by 2 · see citing works
How to manage chronic mesenteric ischemia? A deliberated strategy
Damme, H. V., Boesmans, E., Creemers, E., & Defraigne, J.-O. (2019) · Acta chirurgica Belgica · doi:10.1080/00015458.2019.1675971 · Cited by 2 · see citing works
“and 2016, revealed the rise of endovascular repair (57% of cases), with a better short-term outcome, but a worse long-term primary patency [4].”
BackgroundInfluentialIshida, N., Kumada, Y., Kawai, N., Nakamura, Y., Mori, A., & Kimura, M. (2023) · Annals of Vascular Diseases · doi:10.3400/avd.cr.22-00106 · Cited by 2 · see citing works
Chronic mesenteric ischemia: a case report and review of the literature
Akasheva, D. U., Zhigareva, E. I., Kuznetsova, I. V., Rudenko, B. A., & Drapkina, O. M. (2020) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2020-1-2379 · Cited by 2 · see citing works
Schmid, B., Gonçalves, V. A., Freire, L. M. D., Nasser, F., & Menezes, F. H. (2024) · Jornal Vascular Brasileiro · doi:10.1590/1677-5449.202301482 · Cited by 1 · see citing works
“8,11 Clinical risk stratification is the first step to guide the decision on treatment approach.”
BackgroundAdam, Y. A., & Nicholls, J. (2025) · Surgery (Oxford) · doi:10.1016/j.mpsur.2025.03.009 · Cited by 1 · see citing works
Current management of chronic mesenteric ischemia: A comprehensive review
Anand, U., Maheshwari, N., Khandelwal, V., Paladugu, S. V., Gorsi, U., & Savlania, A. (2025) · Indian Journal of Gastroenterology · doi:10.1007/s12664-025-01884-3 · Cited by 1 · see citing works
“A meta-analysis by Alahdab et al. [29] involving 18,726 patients found significantly higher in-hospital complication rates with open revascularization (relative risk [RR] 2.2, confidence interval [CI] 1.8–2.6), while endovascular therapy had higher three-year recurrence (RR 0.47, CI 0.34–0.66) but…”
InfluentialFrench Nationwide Outcomes after Revascularisation for Acute and Chronic Mesenteric Ischaemia
Lareyre, F., Chierici, A. P., & Raffort, J. (2026) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2026.05.038 · Cited by 1 · see citing works
Kasprzak, B. (2020) · Gefässchirurgie · doi:10.1007/s00772-019-00599-y · Cited by 1 · see citing works
Nicholls, J., & Brooks, M. J. (2022) · Surgery (Oxford) · doi:10.1016/j.mpsur.2022.05.023 · Cited by 1 · see citing works
Chronische mesenteriale Ischämie
Menges, A., Stoklasa, K., Meuli, L., Reutersberg, B., & Zimmermann, A. (2022) · Gefässchirurgie · doi:10.1007/s00772-022-00931-z · Cited by 1 · see citing works
Chronic mesenteric ischemia: causes, methods of diagnosis and treatment
Bugurov, S., Karpenko, A. A., Osipova, O. S., Гостев, А. А., Saaya, S. B., Cheban, A. V., Mochalova, A. B., Ignatenko, P. V., Rabtsun, A. A., Obedinskiy, A. A., et al. (2022) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2022-3183 · Cited by 1 · see citing works
Delmotte, P.-R., Fron, C., & Monsel, A. (2023) · EMC - Anestesia-Reanimación · doi:10.1016/s1280-4703(23)47652-9 · Cited by 1 · see citing works
Isquemia mesentérica e suas possibilidades diagnósticas: uma revisão integrativa da literatura
Augusto, L. B. X., Feres, M. L. A. D., Lemos, M. E. F., & Costa, J. S. P. (2023) · Brazilian Journal of Health Review · doi:10.34119/bjhrv6n4-223 · Cited by 1 · see citing works
Computed tomography diagnostics of acute and chronic mesenteric ischemia
Koshelev, E. G., Belyaev, G. Y., & Егоров, А. А. (2023) · Pirogov Russian Journal of Surgery · doi:10.17116/hirurgia202312167 · Cited by 1 · see citing works
Bastian, M. B., Wessendorf, J., Scheschenja, M., König, A. M., Nadjiri, J., & Mahnken, A. H. (2024) · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · doi:10.1055/a-2258-3437 · Cited by 1 · see citing works
“Current treatment modalities for CMI encompass a range of options, with endovascular interventions being of paramount importance in addition to open surgical procedures, due to their lower in-hospital mortality rate and lower complication profiles [3 – 5].”
BackgroundAxillary to Superior Mesenteric Artery Bypass as a Viable Solution for Chronic Mesenteric Ischemia
Almatroud, L., Billiar, I., Chess, B. A., & Elrakhawy, M. (2024) · Cureus · doi:10.7759/cureus.75524 · Cited by 1 · see citing works
Harish, K. B., Chervonski, E., Rokosh, R. S., Garg, K., Berland, T. L., Sadek, M., Teter, K., Rockman, C. R., Jacobowitz, G. R., & Maldonado, T. S. (2025) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2025.04.022 · Cited by 1 · see citing works
Pedersoli, F., Zimmermann, M., Schulze-Hagen, M. F., Sieben, P., Barzakova, E., Goerg, F., Keil, S., Gombert, A., Kuhl, C. K., Isfort, P., et al. (2020) · Vascular and Endovascular Surgery · doi:10.1177/1538574420927132 · Cited by 1 · see citing works
Ara, S. M., Fueyo, M. J. G., del Barrio-Fernández, M., Arias, C. N., & Samos, R. F. (2021) · Angiología · doi:10.20960/angiologia.00293
Protocolo diagnóstico y terapéutico de las lesiones de las arterias mesentéricas
García, S. V., Cortés, R. P., Hernández, J. A. T., & Sánchez, F. S. L. (2021) · Medicine - Programa de Formación Médica Continuada Acreditado · doi:10.1016/j.med.2021.08.005
Treatment of chronic mesenteric ischemia using ROMS technique and reentry catheter
Rodríguez, R. G., & Fajardo, E. (2021) · Angiología · doi:10.20960/angiologia.00354
92 Chronische mesenteriale Ischämie
de Bucourt, M. (2020) · Referenz Radiologie – Gefäße · doi:10.1055/b-0040-179569
Intestinal ischemia and vasculitides
Malagelada, J., & Malagelada, C. (2022) · Yamada's Textbook of Gastroenterology · doi:10.1002/9781119600206.ch114
Gupta, A. A., Bansal, A., & Patel, R. A. G. (2022) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2022.101164
Acute and Chronic Mesenteric Ischemia
Conway, A. M., Carroccio, A., & Rosen, R. J. (2022) · Interventional Cardiology · doi:10.1002/9781119697367.ch78
van Dijk, L. J. D., & Verhagen, H. J. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65687-8
Delmotte, P.-R., Fron, C., & Monsel, A. (2023) · EMC - Anestesia-Rianimazione · doi:10.1016/s1283-0771(23)47674-8
Hirschl, D. A. (2023) · Wiley eBooks · doi:10.1002/9781119467779.ch7
Григорьевна, Ш. А., Lisitsa, A. A., Вячеславович, Д. Д., & Komlev, A. E. (2024) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-217-9-75-84
Grewal, S., Kansagra, K., Stone, J. R., & Vatakencherry, G. (2024) · Springer eBooks · doi:10.1007/978-3-031-52546-9_27
Mesenteric ischemia caused by chronic occlusion of multiple mesenteric arteries: a case report
Zhao, Q.-M., Xu, Z.-Y., & Wang, H. (2024) · Surgical Case Reports · doi:10.1186/s40792-024-02013-6
Ying, G., Hill, A., Taylor, S., & Dean, A. (2024) · EJVES Vascular Forum · doi:10.1016/j.ejvsvf.2024.10.002
“3,4 There is minimal literature describing the management of AMI secondary to mesenteric angioplasty and stenting.”
BackgroundChronic Ischemic Gastritis in a Patient With a History of Cancer and Atherosclerotic Disease
Parisi, I. M., Vattiato, C., Caramia, V., Sottotetti, F., Ciarfella, A., & Vjero, K. (2024) · ACG Case Reports Journal · doi:10.14309/crj.0000000000001542
Galyfos, G. C., Chamzin, A., Moisidis, I., Chatzopoulou, D., Kravari, I., Kapoutsi, M.-C., Palaios, A., Sigala, F., & Filis, K. (2025) · Journal of Endovascular Therapy · doi:10.1177/15266028251333627
“22 However, in the present review, ER was associated with a higher survival up to 3 years, but a lower survival within 5 years after treatment.”
InfluentialEndovascular management of mesenteric ischemia
Raupach, J., Fejfar, T., Hudák, A., Dvorak, P., Ryška, P., Vajda, M., Čabelková, P., Renc, O., Krajina, A., & Malý, R. (2021) · Česká radiologie · doi:10.55095/cesradiol2021/015
A Narrative Review of Endovascular Approaches for Chronic Mesenteric Ischemia
Nagatomi, S., Kanamori, D., & Yamamoto, H. (2025) · Interventional Radiology · doi:10.22575/interventionalradiology.2024-0057
“Revascularization is indicated in symptomatic patients with CMI to prevent progression to acute mesenteric ischemia and improve quality of life [26].”
InfluentialApproach to Mesenteric Ischemia in the ICU
Mishra, S. B., Samal, S., & Panda, S. (2025) · Springer eBooks · doi:10.1007/978-981-95-0179-3_36
- Authors
- Alahdab, F., Arwani, R., Pasha, A. K., Razouki, Z. A., Prokop, L. J., Huber, T. S., & Murad, M. H.
- Affiliations
- Mayo Clinic (US)
- Ain Shams University (EG)
- University of Florida Health (US)
- Corresponding author
- Murad, M. Hassan
- ORCID
- Venue
- Journal of Vascular Surgery
- Publisher
- Elsevier BV
- Published
- 2018-05
- Volume
- 67
- Issue
- 5
- Pages
- 1598-1605
- ISSN
- 0741-5214 (ISSN-L)
- OpenAlex
- W2791789420
- Cited by
- 114
- References
- 26
- Citations by year
- 2026: 15 · 2025: 12 · 2024: 17 · 2023: 17 · 2022: 15 · 2021: 14 · 2020: 15 · 2019: 6 · 2018: 3
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Vascular Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
- Health Sciences › Medicine › Surgery › Vascular anomalies and interventions
- Keywords
- chronic mesenteric ischemia, endovascular revascularization, open surgical revascularization, mesenteric artery stenosis, in-hospital complications, 30-day mortality, recurrence, long-term survival, graft patency
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Chronic Disease, Female, Humans, Male, Mesenteric Vascular Occlusion, Middle Aged, Recurrence, Risk Factors, Splanchnic Circulation, Time Factors, Vascular Patency, Vascular Surgical Procedures, Odds Ratio, Treatment Outcome, Young Adult, Endovascular Procedures, Mesenteric Ischemia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
