The DOI matches its Crossref record; 173 of the 178 references it cites were found in a registry or an index.
Healthy aging diets other than the Mediterranean: A focus on the Okinawan diet
Open accessAbstract
The traditional diet in Okinawa is anchored by root vegetables (principally sweet potatoes), green and yellow vegetables, soybean-based foods, and medicinal plants. Marine foods, lean meats, fruit, medicinal garnishes and spices, tea, alcohol are also moderately consumed. Many characteristics of the traditional Okinawan diet are shared with other healthy dietary patterns, including the traditional Mediterranean diet, DASH diet, and Portfolio diet. All these dietary patterns are associated with reduced risk for cardiovascular disease, among other age-associated diseases. Overall, the important shared features of these healthy dietary patterns include: high intake of unrefined carbohydrates, moderate protein intake with emphasis on vegetables/legumes, fish, and lean meats as sources, and a healthy fat profile (higher in mono/polyunsaturated fats, lower in saturated fat; rich in omega-3). The healthy fat intake is likely one mechanism for reducing inflammation, optimizing cholesterol, and other risk factors. Additionally, the lower caloric density of plant-rich diets results in lower caloric intake with concomitant high intake of phytonutrients and antioxidants. Other shared features include low glycemic load, less inflammation and oxidative stress, and potential modulation of aging-related biological pathways. This may reduce risk for chronic age-associated diseases and promote healthy aging and longevity.
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“The Okinawans’ diet, characterized by a substantial consumption of vegetables, legumes, and sweet potatoes, is inherently plant-based and low in calories [7,156,157,158,159,160,161].”
From The Power of Environment: A Comprehensive Review of the Exposome's Role in Healthy Aging, Longevity, and Preventive Medicine-Lessons from Blue Zones and Cilento (2025) · cites this paper as [158]
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Flagged first, then by citations
5 of the 178 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- FDA, 1999, Food labeling: health claims; soy protein and coronary heart disease, Fed. Regist., 64, 57699
- Willcox, 2012, Gender gap in healthspan and life expectancy in Okinawa: health behaviours, Asian J. Gerontol. Geriatr., 7, 49
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Aiello, A., Caruso, C., & Accardi, G. (2019) · Encyclopedia of Gerontology and Population Aging · doi:10.1007/978-3-319-69892-2_134-1 · Cited by 8
Metadata
- Authors
- Willcox, D. C., Scapagnini, G., & Willcox, B. J.
- Affiliations
- University of Hawaiʻi at Mānoa (US)
- University of Molise (IT)
- Corresponding author
- Willcox, Donald Craig
- Venue
- Mechanisms of Ageing and Development
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 136-137
- Pages
- 148-162
- ISSN
- 0047-6374 (ISSN-L)
- PMC
- PMC5403516
- OpenAlex
- W1991295722
- Cited by
- 273
- References
- 178
- Citations by year
- 2026: 15 · 2025: 34 · 2024: 17 · 2023: 33 · 2022: 24 · 2021: 27 · 2020: 27 · 2019: 22 · 2018: 24 · 2017: 22 · 2016: 13 · 2015: 11 · 2014: 4
- FWCI
- 2.55
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Mechanisms of Ageing and Development (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Archivio Istituzionale della Ricerca - Università degli Studi del Molise (submittedVersion)
- Funders
- National Institutes of Health (5r01ag038707-04)
- National Institute on Aging (R01-AG-038707, R01AG027060)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Keywords
- Okinawan diet, healthy aging, Mediterranean diet, DASH diet, Portfolio diet, traditional diet, cardiovascular disease, omega-3 fatty acids, plant-based diet, phytochemicals, antioxidants, inflammation, oxidative stress, longevity, age-related diseases, root vegetables, Ipomoea batatas, medicinal plants
- MeSH terms
- Aging, Diet, Dietary Fats, Feeding Behavior, Fish Products, Fruit, Humans, Inflammation, Insulin, Japan, Longevity, Risk Factors, Seaweed, Vegetables, Biomarkers, Free Radical Scavengers, Spices, Cucurbitaceae, Curcuma, Diet, Mediterranean, Soy Foods, Nutritional Sciences, Diet, Western
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