Cited by 273Nutritional Studies and DietDietary Effects on HealthNutrition and Health Studies

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Healthy aging diets other than the Mediterranean: A focus on the Okinawan diet

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Willcox, Donald Craig, Scapagnini, Giovanni, Willcox, Bradley J.·2014·Mechanisms of Ageing and Development

DOI 10.1016/j.mad.2014.01.002PMC PMC5403516

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Abstract

The traditional diet in Okinawa is anchored by root vegetables (principally sweet potatoes), green and yellow vegetables, soybean-based foods, and medicinal plants. Marine foods, lean meats, fruit, medicinal garnishes and spices, tea, alcohol are also moderately consumed. Many characteristics of the traditional Okinawan diet are shared with other healthy dietary patterns, including the traditional Mediterranean diet, DASH diet, and Portfolio diet. All these dietary patterns are associated with reduced risk for cardiovascular disease, among other age-associated diseases. Overall, the important shared features of these healthy dietary patterns include: high intake of unrefined carbohydrates, moderate protein intake with emphasis on vegetables/legumes, fish, and lean meats as sources, and a healthy fat profile (higher in mono/polyunsaturated fats, lower in saturated fat; rich in omega-3). The healthy fat intake is likely one mechanism for reducing inflammation, optimizing cholesterol, and other risk factors. Additionally, the lower caloric density of plant-rich diets results in lower caloric intake with concomitant high intake of phytonutrients and antioxidants. Other shared features include low glycemic load, less inflammation and oxidative stress, and potential modulation of aging-related biological pathways. This may reduce risk for chronic age-associated diseases and promote healthy aging and longevity.

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Authors: Willcox, D. C., Scapagnini, G., & Willcox, B. J.
Affiliations: University of Hawaiʻi at Mānoa (US)
University of Molise (IT)
Corresponding author: Willcox, Donald Craig
ORCID: Scapagnini, Giovanni
Willcox, Bradley J.
Venue: Mechanisms of Ageing and Development
Publisher: Elsevier BV
Published: 2014-03
Volume: 136-137
Pages: 148-162
ISSN: 0047-6374 (ISSN-L)
DOI: 10.1016/j.mad.2014.01.002
PMC: PMC5403516
OpenAlex: W1991295722
Cited by: 273
References: 178
Citations by year: 2026: 15 · 2025: 34 · 2024: 17 · 2023: 33 · 2022: 24 · 2021: 27 · 2020: 27 · 2019: 22 · 2018: 24 · 2017: 22 · 2016: 13 · 2015: 11 · 2014: 4
FWCI: 2.55
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Mechanisms of Ageing and Development (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Archivio Istituzionale della Ricerca - Università degli Studi del Molise (submittedVersion)
Funders: National Institutes of Health (5r01ag038707-04)
National Institute on Aging (R01-AG-038707, R01AG027060)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
Keywords: Okinawan diet, healthy aging, Mediterranean diet, DASH diet, Portfolio diet, traditional diet, cardiovascular disease, omega-3 fatty acids, plant-based diet, phytochemicals, antioxidants, inflammation, oxidative stress, longevity, age-related diseases, root vegetables, Ipomoea batatas, medicinal plants
MeSH terms: Aging, Diet, Dietary Fats, Feeding Behavior, Fish Products, Fruit, Humans, Inflammation, Insulin, Japan, Longevity, Risk Factors, Seaweed, Vegetables, Biomarkers, Free Radical Scavengers, Spices, Cucurbitaceae, Curcuma, Diet, Mediterranean, Soy Foods, Nutritional Sciences, Diet, Western

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Healthy aging diets other than the Mediterranean: A focus on the Okinawan diet

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