The short-term effects of graded activity versus physiotherapy in patients with chronic low back pain: A randomized controlled trial
Open accessAbstract
Background Chronic low back pain is one of the most common problematic health conditions worldwide and is highly associated with disability, quality of life, emotional changes, and work absenteeism. Graded activity programs, based on cognitive behavioral therapy, and exercises are common treatments for patients with low back pain. However, recent evidence has shown that there is no evidence to support graded activity for patients with chronic nonspecific low back pain.Aim to compare the effectiveness of graded activity and physiotherapy in patients with chronic nonspecific low back pain.Methods A total of 66 patients with chronic nonspecific low back pain were randomized to perform either graded activity (moderate intensity treadmill walking, brief education and strength exercises) or physiotherapy (strengthening, stretching and motor control). These patients received individual sessions twice a week for six weeks. The primary measures were intensity of pain (Pain Numerical Rating Scale) and disability (Rolland Morris Disability Questionnaire).Results After six weeks, significant improvements have been observed in all outcome measures of both groups, with a non-significant difference between the groups. For intensity of pain (mean difference = 0.1 points, 95% confidence interval [CI] = -1.1-1.3) and disability (mean difference = 0.8 points, 95% confidence interval [CI] = -2.6-4.2). No differences were found in the remaining outcomes.Conclusion The results of this study suggest that graded activity and physiotherapy showed to be effective and have similar effects for patients with chronic nonspecific low back pain.
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Physiotherapy has a beneficial effect on pain intensity and physical function for musculoskeletal pain.
“For musculoskeletal pain, current research confirms the beneficial effect of physiotherapy on both pain intensity and on physical function [53].”
From Identification and Management of Chronic Pain in Primary Care: a Review (2016) · cites this paper as [53]
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Wolf, U. (2016) · Springer eBooks · doi:10.1007/978-3-642-29775-5_19
Managing chronic pain in primary care
Mills, S. E. E., & Smith, B. H. (2022) · Wiley eBooks · doi:10.1002/9781119701170.ch13
Khan, M. A., Aljohani, N. M., Alsehemi, S. A., Altohami, A. Y., Hakami, M., & Alahmadi, O. A. (2026) · Physiotherapy - The Journal of Indian Association of Physiotherapists · doi:10.4103/pjiap.pjiap_63_25
Ceulemans, D., Goudman, L., Reneman, M. F., Moens, M., Smedt, A. D., Godderis, L., Lavreysen, O., Callens, J., de Velde, V. V., & VELDE, D. V. D. (2026) · Journal of Occupational Rehabilitation · doi:10.1007/s10926-026-10445-0
- Authors
- Magalhães, M. O., Muzi, L. H., Comachio, J., Burke, T. N., Renovato França, F. J., Vidal Ramos, L. A., Leão Almeida, G. P., de Moura Campos Carvalho-e-Silva, A. P., & Marques, A. P.
- Affiliations
- Universidade de São Paulo (BR)
- Venue
- Manual Therapy
- Publisher
- Elsevier BV
- Published
- 2015-08
- Volume
- 20
- Issue
- 4
- Pages
- 603-609
- ISSN
- 1356-689X (ISSN-L)
- OpenAlex
- W2003441451
- Cited by
- 50
- References
- 52
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 3 · 2023: 3 · 2022: 5 · 2021: 8 · 2020: 6 · 2019: 5 · 2018: 4 · 2017: 4 · 2016: 7
- FWCI
- 3.60
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Manual Therapy (publishedVersion)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Funders
- Fundação de Amparo a Pesquisa do Estado de São Paulo (FAPESP), Brazil (2012/18182-5)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Pathology and Forensic Medicine › Spine and Intervertebral Disc Pathology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- chronic non-specific low back pain, graded activity, physiotherapy, treadmill walking, resistance training, stretching, motor control, pain intensity, disability, cognitive behavioral therapy
- MeSH terms
- Adult, Exercise Therapy, Female, Health Education, Health Status, Humans, Male, Middle Aged, Pain Measurement, Quality of Life, Exercise, Low Back Pain, Behavior Control
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