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Cited by 224Cardiovascular and exercise physiologyPhysical Activity and HealthSports Performance and Training

The DOI matches its Crossref record; 18 of the 19 references it cites were found in a registry or an index.

Separate effects of intensity and amount of exercise on interindividual cardiorespiratory fitness response.

Ross, Robert, de Lannoy, Louise, Stotz, Paula J.·2015·Mayo Clinic Proceedings
DOI 10.1016/j.mayocp.2015.07.024
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Abstract

Objective To determine the separate effects of exercise intensity and amount on interindividual cardiorespiratory fitness (CRF) response.Participants and methods Participants were 121 (75 females, 62%) sedentary, middle-aged (mean [SD] age, 53.2 [7.5] years), abdominally obese adults who completed at least 90% of 5 weekly exercise sessions prescribed over a 24-week intervention. Participants were randomly assigned to (1) low-amount, low-intensity exercise (LALI) (180 and 300 kcal per session for women and men, respectively, at 50% of CRF [VO 2peak]; n=39), (2) high-amount, low-intensity exercise (HALI) (360 and 600 kcal per session for women and men, respectively, at 50% of CRF; n=51), or high-amount, high-intensity exercise (HAHI) (360 and 600 kcal per session for women and men, respectively, at 75% of CRF; n=31). Cardiorespiratory fitness was measured using a treadmill test at 4, 8, 16, and 24 weeks. The study duration was September 1, 2009, through May 31, 2013.Results Cardiorespiratory fitness increased within all 3 groups at 24 weeks (P<.001). At 24 weeks, 38.5% (15 of 39), 17.6% (9 of 51), and 0% (0 of 31) of the participants within the LALI, HALI, and HAHI groups, respectively, were CRF nonresponders. At a fixed exercise intensity, increasing exercise amount reduced the rate of nonresponse by 50% (P=.02). At a fixed amount of exercise, increasing the exercise intensity eliminated nonresponse (P=.001). Exposure to exercise decreased the number of CRF nonresponders between 4 and 8 weeks for LALI and by 16 weeks for HALI but plateaued thereafter. For HAHI, the number of CRF nonresponders decreased continually over the 24 weeks.Conclusion For a fixed amount of exercise, increasing exercise intensity consistent with consensus recommendations eliminated CRF nonresponse. Low-intensity exercise may not be sufficient to improve CRF for a substantial proportion of sedentary obese adults.

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Metadata

Authors
Ross, R., de Lannoy, L., & Stotz, P. J.
Affiliations
Queen's University (CA)
Corresponding author
Ross, Robert
ORCID
Venue
Mayo Clinic Proceedings
Publisher
Elsevier BV
Published
2015-11
Volume
90
Issue
11
Pages
1506-1514
ISSN
0025-6196 (ISSN-L)
DOI
10.1016/j.mayocp.2015.07.024
OpenAlex
W2100550631
Cited by
224
References
19
Citations by year
2026: 13 · 2025: 17 · 2024: 26 · 2023: 19 · 2022: 23 · 2021: 24 · 2020: 23 · 2019: 31 · 2018: 22 · 2017: 15 · 2016: 11
FWCI
31.28
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Mayo Clinic Proceedings (publishedVersion)
  • PubMed (publishedVersion)
Funders
Canadian Institutes of Health Research
Topics
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
Keywords
cardiorespiratory fitness, exercise intensity, high-intensity interval training, sedentary adults, abdominal obesity, middle-aged adults, peak oxygen uptake, exercise prescription, sex differences in exercise response, exercise frequency, training duration
MeSH terms
Adult, Exercise Test, Exercise Therapy, Physical Exertion, Female, Humans, Male, Middle Aged, Monitoring, Physiologic, Physical Fitness, Treatment Outcome, Obesity, Abdominal, Sedentary Behavior

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